| Compound ID |
Compound Name |
Compound Formula |
|
CP0007430
|
IBRUTINIB
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|
C25H24N6O2
|
2
|
| 1 |
EC50 = 49 nM
|
|
|
| 2 |
IC50 = 101 nM
|
|
|
|
CP0033646
|
AZD-9291
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|
C28H33N7O2
|
5
|
| 1 |
EC50 = 667 nM
|
|
|
| 2 |
IC50 = 141 nM
|
|
|
| 3 |
IC50 = 322 nM
|
|
|
| 4 |
IC50 = 911 nM
|
|
|
| 5 |
IC50 = 2823 nM
|
|
|
|
CP0389770
|
N-[2-[2-(dimethylamino)ethyl-methylamino]-4-methoxy-5-[(5-naphthalen-2-yl-1H-indazol-3-yl)amino]phenyl]prop-2-enamide
Show/Hide
|
C32H34N6O2
|
2
|
| 1 |
EC50 = 1000 nM
|
|
|
| 2 |
EC50 = 1765 nM
|
|
|
|
CP0378732
|
N-[2-[2-(dimethylamino)ethyl-methylamino]-5-[[6-[4-(dimethylamino)phenyl]-1H-indazol-3-yl]amino]-4-methoxyphenyl]prop-2-enamide
Show/Hide
|
C30H37N7O2
|
1
|
| 1 |
EC50 = 1411 nM
|
|
|
|
CP0547085
|
N-[2-[2-(dimethylamino)ethyl-methylamino]-4-methoxy-5-[(6-naphthalen-2-yl-1H-indazol-3-yl)amino]phenyl]prop-2-enamide
Show/Hide
|
C32H34N6O2
|
1
|
| 1 |
EC50 = 1652 nM
|
|
|
|
CP0065286
|
AVL-301
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|
C27H28F3N7O3
|
1
|
| 1 |
EC50 = 1655 nM
|
|
|
|
CP0378734
|
N-[2-[2-(dimethylamino)ethyl-methylamino]-5-[[5-(4-fluorophenyl)-1H-indazol-3-yl]amino]-4-methoxyphenyl]prop-2-enamide
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|
C28H31FN6O2
|
1
|
| 1 |
EC50 = 2070 nM
|
|
|
|
CP0036082
|
N-(3-chloro-4-fluorophenyl)-7-methoxy-6-(3-morpholin-4-ylpropoxy)quinazolin-4-amine
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|
C22H24ClFN4O3
|
4
|
| 1 |
EC50 = 2162 nM
|
|
|
| 2 |
IC50 < 15 nM
|
|
|
| 3 |
IC50 = 23 nM
|
|
|
| 4 |
IC50 = 1080 nM
|
|
|
|
CP0410181
|
N-[2-[2-(dimethylamino)ethyl-methylamino]-5-[[6-(4-fluorophenyl)-1H-indazol-3-yl]amino]-4-methoxyphenyl]prop-2-enamide
Show/Hide
|
C28H31FN6O2
|
1
|
| 1 |
EC50 = 2165 nM
|
|
|
|
CP0397862
|
N-[2-[2-(dimethylamino)ethyl-methylamino]-4-methoxy-5-[[6-(1-methylindol-3-yl)-1H-indazol-3-yl]amino]phenyl]prop-2-enamide
Show/Hide
|
C31H35N7O2
|
1
|
| 1 |
EC50 = 2206 nM
|
|
|
|
CP0378733
|
N-[2-[2-(dimethylamino)ethyl-methylamino]-5-[[6-(3-fluorophenyl)-1H-indazol-3-yl]amino]-4-methoxyphenyl]prop-2-enamide
Show/Hide
|
C28H31FN6O2
|
1
|
| 1 |
EC50 = 2277 nM
|
|
|
|
CP0476427
|
N-[2-[2-(dimethylamino)ethyl-methylamino]-4-methoxy-5-[(5-naphthalen-1-yl-1H-indazol-3-yl)amino]phenyl]prop-2-enamide
Show/Hide
|
C32H34N6O2
|
1
|
| 1 |
EC50 = 2780 nM
|
|
|
|
CP0548778
|
N-[2-[2-(dimethylamino)ethyl-methylamino]-5-[(6-isoquinolin-4-yl-1H-indazol-3-yl)amino]-4-methoxyphenyl]prop-2-enamide
Show/Hide
|
C31H33N7O2
|
1
|
| 1 |
EC50 = 2822 nM
|
|
|
|
CP0169994
|
N-[2-[2-(dimethylamino)ethyl-methylamino]-5-[[6-(3-fluoroanilino)-1H-indazol-3-yl]amino]-4-methoxyphenyl]prop-2-enamide
Show/Hide
|
C28H32FN7O2
|
1
|
| 1 |
EC50 = 3103 nM
|
|
|
|
CP0378731
|
N-[2-[2-(dimethylamino)ethyl-methylamino]-4-methoxy-5-[(6-naphthalen-1-yl-1H-indazol-3-yl)amino]phenyl]prop-2-enamide
Show/Hide
|
C32H34N6O2
|
1
|
| 1 |
EC50 = 3175 nM
|
|
|
|
CP0476426
|
N-[2-[2-(dimethylamino)ethyl-methylamino]-5-[[6-[3-(dimethylamino)phenyl]-1H-indazol-3-yl]amino]-4-methoxyphenyl]prop-2-enamide
Show/Hide
|
C30H37N7O2
|
1
|
| 1 |
EC50 = 3472 nM
|
|
|
|
CP0544220
|
N-[2-[2-(dimethylamino)ethyl-methylamino]-4-methoxy-5-[[6-[3-(trifluoromethyl)phenyl]-1H-indazol-3-yl]amino]phenyl]prop-2-enamide
Show/Hide
|
C29H31F3N6O2
|
1
|
| 1 |
EC50 = 3539 nM
|
|
|
|
CP0497883
|
N-[2-[2-(dimethylamino)ethyl-methylamino]-4-methoxy-5-[(6-pyridin-4-yl-1H-indazol-3-yl)amino]phenyl]prop-2-enamide
Show/Hide
|
C27H31N7O2
|
1
|
| 1 |
EC50 = 3943 nM
|
|
|
|
CP0492071
|
N-[2-[2-(dimethylamino)ethyl-methylamino]-4-methoxy-5-[(6-pyridin-3-yl-1H-indazol-3-yl)amino]phenyl]prop-2-enamide
Show/Hide
|
C27H31N7O2
|
1
|
| 1 |
EC50 = 5671 nM
|
|
|
|
CP0547871
|
N-[2-[2-(dimethylamino)ethyl-methylamino]-5-(1H-indazol-3-ylamino)phenyl]prop-2-enamide
Show/Hide
|
C21H26N6O
|
1
|
| 1 |
EC50 = 5971 nM
|
|
|
|
CP0441188
|
N-[2-[2-(dimethylamino)ethyl-methylamino]-5-(1H-indazol-3-ylamino)-4-methoxyphenyl]prop-2-enamide
Show/Hide
|
C22H28N6O2
|
1
|
| 1 |
EC50 = 10412 nM
|
|
|
|
CP0476424
|
N-[2-[2-(dimethylamino)ethyl-methylamino]-5-(1H-indazol-3-ylamino)-4-methoxyphenyl]propanamide
Show/Hide
|
C22H30N6O2
|
1
|
| 1 |
EC50 > 30000 nM
|
|
|
|
CP0476425
|
N-[2-[2-(dimethylamino)ethyl-methylamino]-5-(1H-indazol-3-ylamino)phenyl]propanamide
Show/Hide
|
C21H28N6O
|
1
|
| 1 |
EC50 > 30000 nM
|
|
|
|
CP0086121
|
ACP-196
Show/Hide
|
C26H23N7O2
|
1
|
| 1 |
EC50 > 1000 nM
|
|
|
|
CP0538771
|
4-[6-(but-2-ynoylamino)-7-(2-morpholin-4-ylethoxy)quinolin-4-yl]oxy-N-pyridin-2-ylbenzamide
Show/Hide
|
C31H29N5O5
|
1
|
| 1 |
EC50 > 1000 nM
|
|
|
|
CP0548139
|
4-[7-methoxy-6-(5-morpholin-4-ylpent-2-ynoylamino)quinolin-4-yl]oxy-N-pyridin-2-ylbenzamide
Show/Hide
|
C31H29N5O5
|
1
|
| 1 |
EC50 > 1000 nM
|
|
|
|
CP0415016
|
8-[(3-Bromophenyl)amino]-1-methyl-1H-imidazo[4,5-g]-quinazoline
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|
C16H12BrN5
|
1
|
| 1 |
IC50 = 0.01 nM
|
|
|
|
CP0016034
|
8-[(3-Bromophenyl)amino]-3-methyl-3H-imidazo[4,5-g]-quinazoline
Show/Hide
|
C16H12BrN5
|
1
|
| 1 |
IC50 = 0.025 nM
|
|
|
|
CP0011998
|
N-(3-bromophenyl)-6,7-dimethoxyquinazolin-4-amine
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|
C16H14BrN3O2
|
6
|
| 1 |
IC50 = 0.029 nM
|
|
|
| 2 |
IC50 = 4 nM
|
|
|
| 3 |
IC50 < 15 nM
|
|
|
| 4 |
IC50 = 30 nM
|
|
|
| 5 |
IC50 = 200 nM
|
|
|
| 6 |
IC50 = 230 nM
|
|
|
|
CP0381066
|
N-(3,4-dibromophenyl)-6,7-dimethoxyquinazolin-4-amine
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|
C16H13Br2N3O2
|
1
|
| 1 |
IC50 = 0.072 nM
|
|
|
|
CP0365193
|
4-Anilinoquinazoline deriv. 48
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|
C14H11BrN4
|
1
|
| 1 |
IC50 = 0.1 nM
|
|
|
|
CP0375334
|
quinazolin-7-amine
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|
C8H7N3
|
1
|
| 1 |
IC50 = 0.1 nM
|
|
|
|
CP0058543
|
4-Anilinoquinazoline deriv. 54
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|
C14H12BrN5
|
2
|
| 1 |
IC50 = 0.12 nM
|
|
|
| 2 |
IC50 > 1000 nM
|
|
|
|
CP0034847
|
4-Anilinoquinazoline deriv. 53
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|
C14H10BrN3O2
|
1
|
| 1 |
IC50 = 0.17 nM
|
|
|
|
CP0364245
|
N-(3-bromophenyl)-6,7-dipropoxyquinazolin-4-amine
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|
C20H22BrN3O2
|
1
|
| 1 |
IC50 = 0.17 nM
|
|
|
|
CP0033751
|
6,7-dimethoxy-N-[3-(trifluoromethyl)phenyl]quinazolin-4-amine
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|
C17H14F3N3O2
|
1
|
| 1 |
IC50 = 0.24 nM
|
|
|
|
CP0453847
|
4-N-(3-chlorophenyl)quinazoline-4,7-diamine
Show/Hide
|
C14H11ClN4
|
1
|
| 1 |
IC50 = 0.25 nM
|
|
|
|
CP0480572
|
8-[(3-Bromophenyl)amino]-2-methyl-1H-imidazo[4,5-g]-quinazoline
Show/Hide
|
C16H12BrN5
|
1
|
| 1 |
IC50 = 0.29 nM
|
|
|
|
CP0378419
|
EXEL-7647
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|
C24H25Cl2FN4O2
|
1
|
| 1 |
IC50 = 0.3 nM
|
|
|
|
CP0016076
|
N-(3-chlorophenyl)-6,7-dimethoxyquinazolin-4-amine
Show/Hide
|
C16H14ClN3O2
|
1
|
| 1 |
IC50 = 0.31 nM
|
|
|
|
CP0404643
|
8-[(3-Bromophenyl)amino]-1H-pyrazolo[3,4-g]quinazoline
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|
C15H10BrN5
|
1
|
| 1 |
IC50 = 0.34 nM
|
|
|
|
CP0535296
|
4-N-(3-iodophenyl)quinazoline-4,7-diamine
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|
C14H11IN4
|
1
|
| 1 |
IC50 = 0.35 nM
|
|
|
|
CP0878521
|
4-(3'-chloroanilino)-6,7-diethoxyquinazoline hydrochloride
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|
C18H19Cl2N3O2
|
1
|
| 1 |
IC50 = 0.38 nM
|
|
|
|
CP0876121
|
4-(3'-bromoanilino)-6,7-diethoxyquinazoline hydrochloride
Show/Hide
|
C18H19BrClN3O2
|
1
|
| 1 |
IC50 = 0.41 nM
|
|
|
|
CP0064498
|
5-[(3-Bromophenyl)amino]-1H-pyrazolo[4,3-g]quinazoline
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|
C15H10BrN5
|
2
|
| 1 |
IC50 = 0.44 nM
|
|
|
| 2 |
IC50 = 20 nM
|
|
|
|
CP0290381
|
5-[(3-Bromophenyl)amino]-1H-pyrrolo[3,2-g]quinazoline
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|
C16H11BrN4
|
2
|
| 1 |
IC50 = 0.44 nM
|
|
|
| 2 |
IC50 = 22 nM
|
|
|
|
CP0064503
|
4-N-(3-bromophenyl)-7-N-[3-(1H-imidazol-1-yl)propyl]pyrido[4,3-d]pyrimidine-4,7-diamine
Show/Hide
|
C19H18BrN7
|
1
|
| 1 |
IC50 = 0.51 nM
|
|
|
|
CP0876120
|
4-(3'-iodoanilino)-6,7-diethoxyquinazoline hydrochloride
Show/Hide
|
C18H19ClIN3O2
|
1
|
| 1 |
IC50 = 0.64 nM
|
|
|
|
CP0876117
|
PD153035 (HYDROCHLORIDE)
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|
C16H15BrClN3O2
|
1
|
| 1 |
IC50 = 0.66 nM
|
|
|
|
CP0402575
|
4-[(3-Bromophenyl)amino]-5,6,7-trimethoxyquinazoline
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|
C17H16BrN3O3
|
1
|
| 1 |
IC50 = 0.67 nM
|
|
|
|
CP0263940
|
4-N-(3-bromophenyl)-7-N-methylquinazoline-4,6,7-triamine
Show/Hide
|
C15H14BrN5
|
1
|
| 1 |
IC50 = 0.69 nM
|
|
|
|
CP0138773
|
4-Anilinoquinazoline deriv. 45
Show/Hide
|
C14H11BrN4
|
4
|
| 1 |
IC50 = 0.78 nM
|
|
|
| 2 |
IC50 = 0.79 nM
|
|
|
| 3 |
IC50 = 30 nM
|
|
|
| 4 |
IC50 > 10000 nM
|
|
|
|
CP0492315
|
quinazolin-6-amine
Show/Hide
|
C8H7N3
|
1
|
| 1 |
IC50 = 0.79 nM
|
|
|
|
CP0263944
|
N-(3-iodophenyl)-6,7-dimethoxyquinazolin-4-amine
Show/Hide
|
C16H14IN3O2
|
1
|
| 1 |
IC50 = 0.89 nM
|
|
|
|
CP0137249
|
4-N-(3-bromophenyl)-7-N-[2-(1H-imidazol-4-yl)ethyl]pyrido[4,3-d]pyrimidine-4,7-diamine
Show/Hide
|
C18H16BrN7
|
1
|
| 1 |
IC50 = 0.91 nM
|
|
|
|
CP0092892
|
N-(4-bromophenyl)-6,7-dimethoxyquinazolin-4-amine
Show/Hide
|
C16H14BrN3O2
|
2
|
| 1 |
IC50 = 0.96 nM
|
|
|
| 2 |
IC50 = 3600 nM
|
|
|
|
CP0880581
|
4-(3'-iodoanilino)-6,7-dimethoxyquinazoline hydrochloride
Show/Hide
|
C16H15ClIN3O2
|
1
|
| 1 |
IC50 = 1.05 nM
|
|
|
|
CP0410331
|
7-benzyl-4-N-(4-methoxyphenyl)-4-N-methyl-5H-pyrrolo[3,2-d]pyrimidine-2,4-diamine
Show/Hide
|
C21H21N5O
|
1
|
| 1 |
IC50 = 1.1 nM
|
|
|
|
CP0037987
|
N-(3-ethynylphenyl)-6,7-bis(2-methoxyethoxy)quinazolin-4-amine
Show/Hide
|
C22H23N3O4
|
4
|
| 1 |
IC50 = 1.2 nM
|
|
|
| 2 |
IC50 = 30 nM
|
|
|
| 3 |
IC50 = 34 nM
|
|
|
| 4 |
IC50 = 92 nM
|
|
|
|
CP0223055
|
9-[(3-Bromophenyl)amino]-1H-pyrrolo[2,3-f]quinazoline
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|
C16H11BrN4
|
1
|
| 1 |
IC50 = 1.24 nM
|
|
|
|
CP0841359
|
(3-Chloro-phenyl)-(6,7-dimethoxy-quinazolin-4-yl)-amine hydrochloride
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|
C16H15Cl2N3O2
|
1
|
| 1 |
IC50 = 1.26 nM
|
|
|
|
CP0512124
|
8-[(3-Bromophenyl)amino]-1-[2-(dimethylamino)ethyl]-1H-imidazo[4,5-g]quinazoline
Show/Hide
|
C19H19BrN6
|
1
|
| 1 |
IC50 = 1.32 nM
|
|
|
|
CP0391397
|
4-[(3-Bromophenyl)amino]pyrazino[2,3-g]quinazoline
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|
C16H10BrN5
|
1
|
| 1 |
IC50 = 1.7 nM
|
|
|
|
CP0453846
|
4-N-(3-fluorophenyl)quinazoline-4,7-diamine
Show/Hide
|
C14H11FN4
|
1
|
| 1 |
IC50 = 2 nM
|
|
|
|
CP0500969
|
N-[2-[4-(3-chloro-4-fluoroanilino)-7-methoxyquinazolin-6-yl]oxyethyl]-N',N'-dimethylethane-1,2-diamine
Show/Hide
|
C21H25ClFN5O2
|
1
|
| 1 |
IC50 = 2 nM
|
|
|
|
CP0172144
|
N-[4-(3-bromo-4-fluoroanilino)pyrido[3,4-d]pyrimidin-6-yl]prop-2-enamide
Show/Hide
|
C16H11BrFN5O
|
1
|
| 1 |
IC50 = 2.1 nM
|
|
|
|
CP0501887
|
4-N-(3-bromophenyl)-6-N-[(4-methoxyphenyl)methyl]pyrido[3,4-d]pyrimidine-4,6-diamine
Show/Hide
|
C21H18BrN5O
|
1
|
| 1 |
IC50 = 2.3 nM
|
|
|
|
CP0140193
|
N-[4-(3-chloroanilino)quinazolin-6-yl]prop-2-enamide
Show/Hide
|
C17H13ClN4O
|
1
|
| 1 |
IC50 = 2.3 nM
|
|
|
|
CP0906523
|
7-Benzyl-N-(4-methoxyphenyl)-N,2,5-trimethyl-5H-pyrrolo[3,2-d]pyrimidin-4-amine hydrochloride
Show/Hide
|
C23H25ClN4O
|
1
|
| 1 |
IC50 = 2.3 nM
|
|
|
|
CP0309542
|
4-Anilinopyrido[3,4-d]pyrimidine 32
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|
C15H12BrN5O2S
|
1
|
| 1 |
IC50 = 2.4 nM
|
|
|
|
CP0877991
|
7-Benzyl-N-(4-methoxyphenyl)-2,5-dimethyl-5H-pyrrolo[3,2-d]pyrimidin-4-amine hydrochloride
Show/Hide
|
C22H23ClN4O
|
1
|
| 1 |
IC50 = 2.6 nM
|
|
|
|
CP0292283
|
N-[4-(3-bromo-4-fluoroanilino)quinazolin-6-yl]prop-2-enamide
Show/Hide
|
C17H12BrFN4O
|
1
|
| 1 |
IC50 = 2.7 nM
|
|
|
|
CP0035025
|
4-anilinoquinazoline deriv. 2
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|
C17H13BrN4O
|
4
|
| 1 |
IC50 = 2.7 nM
|
|
|
| 2 |
IC50 = 4.3 nM
|
|
|
| 3 |
IC50 = 12 nM
|
|
|
| 4 |
IC50 = 152 nM
|
|
|
|
CP0204726
|
6-Substituted 4-Anilinoquinazoline 33
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|
C16H13BrN4O2S
|
1
|
| 1 |
IC50 = 2.7 nM
|
|
|
|
CP0421667
|
Azixa
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|
C17H17N3O
|
1
|
| 1 |
IC50 = 2.8 nM
|
|
|
|
CP0009227
|
3-(Benzylamino)-4-((3-chlorophenyl)amino)-1H-pyrazolo[3,4-d]pyrimidine
Show/Hide
|
C18H15ClN6
|
1
|
| 1 |
IC50 = 3 nM
|
|
|
|
CP0277315
|
N-[4-(3-bromoanilino)-7-[3-(4-methylpiperazin-1-yl)propoxy]quinazolin-6-yl]prop-2-enamide
Show/Hide
|
C25H29BrN6O2
|
1
|
| 1 |
IC50 = 3 nM
|
|
|
|
CP0131285
|
US8901140, 2
Show/Hide
|
C31H29ClN6O3
|
1
|
| 1 |
IC50 = 3 nM
|
|
|
|
CP0953454
|
{4-[(Z)-3-Bromo-phenylimino]-3-methyl-3,4,4a,8a-tetrahydro-pyrido[4,3-d]pyrimidin-7-yl}-methyl-amine
Show/Hide
|
C15H16BrN5
|
1
|
| 1 |
IC50 = 3.1 nM
|
|
|
|
CP0289160
|
N-[4-(3-chloro-4-fluoroanilino)quinazolin-6-yl]prop-2-enamide
Show/Hide
|
C17H12ClFN4O
|
1
|
| 1 |
IC50 = 3.1 nM
|
|
|
|
CP0459165
|
1-N,1-N,4-N-trimethyl-4-N-(5-methylfuro[2,3-d]pyrimidin-4-yl)benzene-1,4-diamine
Show/Hide
|
C16H18N4O
|
1
|
| 1 |
IC50 = 3.1 nM
|
|
|
|
CP0350007
|
4-N-[3-(trifluoromethyl)phenyl]quinazoline-4,7-diamine
Show/Hide
|
C15H11F3N4
|
1
|
| 1 |
IC50 = 3.3 nM
|
|
|
|
CP0380565
|
N-[4-(3-chloro-4-fluoroanilino)pyrido[3,4-d]pyrimidin-6-yl]prop-2-enamide
Show/Hide
|
C16H11ClFN5O
|
1
|
| 1 |
IC50 = 3.3 nM
|
|
|
|
CP0041544
|
4-Anilinopyrido[3,4-d]pyrimidine 3
Show/Hide
|
C16H12BrN5O
|
1
|
| 1 |
IC50 = 3.4 nM
|
|
|
|
CP0504740
|
4-(6-methoxy-3,4-dihydro-2H-quinolin-1-yl)-2,6-dimethylfuro[2,3-d]pyrimidine
Show/Hide
|
C18H19N3O2
|
1
|
| 1 |
IC50 = 3.4 nM
|
|
|
|
CP0279021
|
7-N-[3-(1H-imidazol-1-yl)propyl]-4-N-(3-methylphenyl)pyrido[4,3-d]pyrimidine-4,7-diamine
Show/Hide
|
C20H21N7
|
1
|
| 1 |
IC50 = 3.5 nM
|
|
|
|
CP0303641
|
2-chloro-N-(4-methoxyphenyl)-N-methylquinazolin-4-amine
Show/Hide
|
C16H14ClN3O
|
1
|
| 1 |
IC50 = 3.6 nM
|
|
|
|
CP0276147
|
4-N-(3-bromophenyl)-7-methoxyquinazoline-4,6-diamine
Show/Hide
|
C15H13BrN4O
|
1
|
| 1 |
IC50 = 3.8 nM
|
|
|
|
CP0364248
|
N-(3-fluorophenyl)-6,7-dimethoxyquinazolin-4-amine
Show/Hide
|
C16H14FN3O2
|
1
|
| 1 |
IC50 = 3.8 nM
|
|
|
|
CP0276148
|
4-N-(3-bromophenyl)-6-N-methylquinazoline-4,6-diamine
Show/Hide
|
C15H13BrN4
|
2
|
| 1 |
IC50 = 4 nM
|
|
|
| 2 |
IC50 = 11 nM
|
|
|
|
CP0527744
|
N-methylquinazolin-7-amine
Show/Hide
|
C9H9N3
|
1
|
| 1 |
IC50 = 4 nM
|
|
|
|
CP0008214
|
3-((3-Hydroxyphenyl)amino)-4-((3-chlorophenyl)amino)-1H-pyrazolo[3,4-d]pyrimidine
Show/Hide
|
C17H13ClN6O
|
1
|
| 1 |
IC50 = 4 nM
|
|
|
|
CP0467756
|
N-(4-ethylphenyl)-N,5-dimethylfuro[2,3-d]pyrimidin-4-amine
Show/Hide
|
C16H17N3O
|
1
|
| 1 |
IC50 = 4 nM
|
|
|
|
CP0106900
|
2-[4-[4-(3-chloro-2-fluoroanilino)-7-methoxyquinazolin-6-yl]oxypiperidin-1-yl]-N-methylacetamide
Show/Hide
|
C23H25ClFN5O3
|
1
|
| 1 |
IC50 = 4 nM
|
|
|
|
CP0465194
|
8-[(3-Bromophenyl)amino]-1H-1,2,3-triazolo[4,5-g]-quinazoline
Show/Hide
|
C14H9BrN6
|
1
|
| 1 |
IC50 = 4.1 nM
|
|
|
|
CP0337686
|
N-[4-(4-phenylmethoxyanilino)quinazolin-6-yl]prop-2-enamide
Show/Hide
|
C24H20N4O2
|
1
|
| 1 |
IC50 = 4.2 nM
|
|
|
|
CP0462843
|
4-[(3-bromophenyl)amino]-6-methoxypyrido[3,2-d]pyrimidine
Show/Hide
|
C14H11BrN4O
|
1
|
| 1 |
IC50 = 4.3 nM
|
|
|
|
CP0436378
|
1-{4-[(3-chlorophenyl)amino-6-quinazolinyl}-3-{2-[N-(2-chloroethyl)-N-methylethylenamine]}triazene
Show/Hide
|
C19H21Cl2N7
|
1
|
| 1 |
IC50 = 4.4 nM
|
|
|
|
CP0347434
|
N-[4-[3-(trifluoromethyl)anilino]quinazolin-6-yl]prop-2-enamide
Show/Hide
|
C18H13F3N4O
|
1
|
| 1 |
IC50 = 4.5 nM
|
|
|
|
CP0318932
|
[(2S)-1-[(2-methylpropan-2-yl)oxy]-3-(2-nitroimidazol-1-yl)propan-2-yl] 4-[(2-hydroxy-5-oxocyclopenta-1,3-dien-1-yl)methylideneamino]benzoate
Show/Hide
|
C23H24N4O7
|
1
|
| 1 |
IC50 = 4.694836 nM
|
|
|
|
CP0263942
|
4-[(3-bromophenyl)amino]quinazolin-7-ol
Show/Hide
|
C14H10BrN3O
|
1
|
| 1 |
IC50 = 4.7 nM
|
|
|
|
CP0142770
|
N-[4-(3-methylanilino)quinazolin-6-yl]prop-2-enamide
Show/Hide
|
C18H16N4O
|
1
|
| 1 |
IC50 = 4.7 nM
|
|
|
|
CP0300427
|
N-[4-(3-bromo-4-fluoroanilino)-7-(3-morpholin-4-ylpropoxy)quinazolin-6-yl]prop-2-enamide
Show/Hide
|
C24H25BrFN5O3
|
1
|
| 1 |
IC50 = 4.7 nM
|
|
|
|
CP0360624
|
N-[4-(4-phenoxyanilino)quinazolin-6-yl]prop-2-enamide
Show/Hide
|
C23H18N4O2
|
1
|
| 1 |
IC50 = 4.8 nM
|
|
|
|
CP0906525
|
1-(7-Benzyl-2,5-dimethyl-5H-pyrrolo[3,2-d]pyrimidin-4-yl)-6-methoxy-1,2,3,4-tetrahydroquinoline hydrochloride
Show/Hide
|
C25H27ClN4O
|
1
|
| 1 |
IC50 = 4.9 nM
|
|
|
|
CP0064504
|
(6,7-Dimethoxy-quinazolin-4-yl)-m-tolyl-amine
Show/Hide
|
C17H17N3O2
|
1
|
| 1 |
IC50 = 5 nM
|
|
|
|
CP0507691
|
1-[4-(3-Chloro-4-fluoro-phenylamino)-7-methoxy-quinazolin-6-yloxy]-3-methylamino-propan-2-ol
Show/Hide
|
C19H20ClFN4O3
|
1
|
| 1 |
IC50 = 5 nM
|
|
|
|
CP0510290
|
1-[Bis-(2-hydroxy-ethyl)-amino]-3-[4-(3-chloro-4-fluoro-phenylamino)-7-methoxy-quinazolin-6-yloxy]-propan-2-ol
Show/Hide
|
C22H26ClFN4O5
|
1
|
| 1 |
IC50 = 5 nM
|
|
|
|
CP0251300
|
6-methoxy-7-(3-morpholinopropoxy)-4-((1R,2S)-2-phenylcyclopropylamino)quinoline-3-carbonitrile
Show/Hide
|
C27H30N4O3
|
1
|
| 1 |
IC50 = 5 nM
|
|
|
|
CP0516899
|
4-(6-methoxy-3,4-dihydro-2H-quinolin-1-yl)-2-methylquinazoline
Show/Hide
|
C19H19N3O
|
1
|
| 1 |
IC50 = 5 nM
|
|
|
|
CP0279348
|
N-[4-(3-bromoanilino)-7-(3-morpholin-4-ylpropoxy)quinazolin-6-yl]prop-2-enamide
Show/Hide
|
C24H26BrN5O3
|
1
|
| 1 |
IC50 = 5.3 nM
|
|
|
|
CP0063802
|
(E)-4-(Methylamino)-but-2-enoic acid [4-(3-chloro-4-fluorophenylamino)-3-cyano-7-ethoxy-quinoline-6-yl]amide
Show/Hide
|
C23H21ClFN5O2
|
1
|
| 1 |
IC50 = 5.35 nM
|
|
|
|
CP0516901
|
2-chloro-4-(6-methoxy-3,4-dihydro-2H-quinolin-1-yl)quinazoline
Show/Hide
|
C18H16ClN3O
|
1
|
| 1 |
IC50 = 5.4 nM
|
|
|
|
CP0300451
|
N-[4-(3-bromoanilino)pyrido[3,2-d]pyrimidin-6-yl]prop-2-enamide
Show/Hide
|
C16H12BrN5O
|
1
|
| 1 |
IC50 = 5.6 nM
|
|
|
|
CP0177498
|
6-methoxy-7-(3-(4-methylpiperazin-1-yl)propoxy)-4-((1R,2S)-2-phenylcyclopropylamino)quinoline-3-carbonitrile
Show/Hide
|
C28H33N5O2
|
1
|
| 1 |
IC50 = 5.7 nM
|
|
|
|
CP0173345
|
4-N-(3-bromophenyl)-6-N-[3-(morpholin-4-yl)propyl]pyrido[3,4-d]pyrimidine-4,6-diamine
Show/Hide
|
C20H23BrN6O
|
1
|
| 1 |
IC50 = 5.9 nM
|
|
|
|
CP0500908
|
1-Amino-3-[4-(3-chloro-4-fluoro-phenylamino)-7-methoxy-quinazolin-6-yloxy]-propan-2-ol
Show/Hide
|
C18H18ClFN4O3
|
1
|
| 1 |
IC50 = 6 nM
|
|
|
|
CP0303487
|
(3-Chloro-phenyl)-(9H-pyrimido[4,5-b]indol-4-yl)-amine
Show/Hide
|
C16H11ClN4
|
2
|
| 1 |
IC50 = 6 nM
|
|
|
| 2 |
IC50 = 120 nM
|
|
|
|
CP0153482
|
DACOMITINIB
Show/Hide
|
C24H25ClFN5O2
|
1
|
| 1 |
IC50 = 6 nM
|
|
|
|
CP0263570
|
4-N-(3-bromophenyl)-6-N-[2-(1H-imidazol-4-yl)ethyl]pyrido[3,4-d]pyrimidine-4,6-diamine
Show/Hide
|
C18H16BrN7
|
1
|
| 1 |
IC50 = 6.3 nM
|
|
|
|
CP0453561
|
(6,7-Dimethoxy-quinazolin-4-yl)-isoquinolin-4-yl-amine
Show/Hide
|
C19H16N4O2
|
1
|
| 1 |
IC50 = 6.4 nM
|
|
|
|
CP0415601
|
1-N,4-N-dimethyl-4-N-(5-methylfuro[2,3-d]pyrimidin-4-yl)benzene-1,4-diamine
Show/Hide
|
C15H16N4O
|
1
|
| 1 |
IC50 = 6.4 nM
|
|
|
|
CP0195791
|
4-N-(3-bromophenyl)-7-chloroquinazoline-4,6-diamine
Show/Hide
|
C14H10BrClN4
|
1
|
| 1 |
IC50 = 6.5 nM
|
|
|
|
CP0092273
|
4-N-(3-bromophenyl)-7-N-methylquinazoline-4,7-diamine
Show/Hide
|
C15H13BrN4
|
1
|
| 1 |
IC50 = 7 nM
|
|
|
|
CP0502464
|
N-methylquinazolin-6-amine
Show/Hide
|
C9H9N3
|
1
|
| 1 |
IC50 = 7 nM
|
|
|
|
CP0403758
|
(3-Chloro-4-fluoro-phenyl)-[6-(2-dimethylamino-ethoxy)-7-methoxy-quinazolin-4-yl]-amine
Show/Hide
|
C19H20ClFN4O2
|
1
|
| 1 |
IC50 = 7 nM
|
|
|
|
CP0274443
|
(2R,3S)-N-(4-(3-Bromoanilino)quinazolin-6-yl)-3-(piperidin-1-ylmethyl)oxirane-2-carboxamide
Show/Hide
|
C23H24BrN5O2
|
2
|
| 1 |
IC50 = 7 nM
|
|
|
| 2 |
IC50 = 44 nM
|
|
|
|
CP0415604
|
N-(4-methoxyphenyl)-5-methyl-N-propylfuro[2,3-d]pyrimidin-4-amine
Show/Hide
|
C17H19N3O2
|
1
|
| 1 |
IC50 = 7.1 nM
|
|
|
|
CP0137254
|
7-N-[2-(1H-imidazol-4-yl)ethyl]-4-N-(3-methylphenyl)pyrido[4,3-d]pyrimidine-4,7-diamine
Show/Hide
|
C19H19N7
|
1
|
| 1 |
IC50 = 7.2 nM
|
|
|
|
CP0548534
|
N,5-dimethyl-N-(4-methylsulfanylphenyl)furo[2,3-d]pyrimidin-4-amine
Show/Hide
|
C15H15N3OS
|
1
|
| 1 |
IC50 = 7.2 nM
|
|
|
|
CP0036058
|
N-[4-(3-chloro-4-fluoroanilino)-7-(3-morpholin-4-ylpropoxy)quinazolin-6-yl]prop-2-enamide
Show/Hide
|
C24H25ClFN5O3
|
1
|
| 1 |
IC50 = 7.4 nM
|
|
|
|
CP0642885
|
N-(4-(3-chloro-4-fluorophenylamino)-7-(3-morpholinopropoxy)quinazolin-6-yl)acrylamide dihydrochloride
Show/Hide
|
C24H27Cl3FN5O3
|
1
|
| 1 |
IC50 = 7.4 nM
|
|
|
|
CP0088404
|
(2E)-N-[4-(3-Bromoanilino)pyrido[3,4-d]pyrimidin-6-yl]-2-butenamide
Show/Hide
|
C17H14BrN5O
|
1
|
| 1 |
IC50 = 7.7 nM
|
|
|
|
CP0275875
|
4-N-(3-bromophenyl)-6-N-[2-(morpholin-4-yl)ethyl]pyrido[3,4-d]pyrimidine-4,6-diamine
Show/Hide
|
C19H21BrN6O
|
2
|
| 1 |
IC50 = 7.9 nM
|
|
|
| 2 |
IC50 = 7900 nM
|
|
|
|
CP0293773
|
N-[4-(3-bromoanilino)-7-[4-(dimethylamino)butoxy]quinazolin-6-yl]prop-2-enamide
Show/Hide
|
C23H26BrN5O2
|
1
|
| 1 |
IC50 = 7.9 nM
|
|
|
|
CP0496572
|
(3-Chloro-4-fluoro-phenyl)-{7-methoxy-6-[2-(2-methoxy-ethylamino)-ethoxy]-quinazolin-4-yl}-amine
Show/Hide
|
C20H22ClFN4O3
|
1
|
| 1 |
IC50 = 8 nM
|
|
|
|
CP0509632
|
1-[4-(3-Chloro-4-fluoro-phenylamino)-7-methoxy-quinazolin-6-yloxy]-3-imidazol-1-yl-propan-2-ol
Show/Hide
|
C21H19ClFN5O3
|
1
|
| 1 |
IC50 = 8 nM
|
|
|
|
CP0545066
|
(3-Chloro-4-fluoro-phenyl)-[7-methoxy-6-(2-methylamino-ethoxy)-quinazolin-4-yl]-amine
Show/Hide
|
C18H18ClFN4O2
|
1
|
| 1 |
IC50 = 8 nM
|
|
|
|
CP0250525
|
US8901140, 9
Show/Hide
|
C24H25ClFN5O2
|
1
|
| 1 |
IC50 = 8 nM
|
|
|
|
CP0039199
|
(E)-N-[4-(3-chloro-4-fluoro-anilino)-3-cyano-7-ethoxy-6-quinolyl]-4-(dimethylamino)but-2-enamide
Show/Hide
|
C24H23ClFN5O2
|
2
|
| 1 |
IC50 = 8.02 nM
|
|
|
| 2 |
IC50 = 39 nM
|
|
|
|
CP0214566
|
4-N-(3-bromophenyl)-7-N-[3-(morpholin-4-yl)propyl]pyrido[4,3-d]pyrimidine-4,7-diamine
Show/Hide
|
C20H23BrN6O
|
1
|
| 1 |
IC50 = 8.1 nM
|
|
|
|
CP0288932
|
4-N-(3-bromophenyl)-6-N-[2-(pyridin-2-yl)ethyl]pyrido[3,4-d]pyrimidine-4,6-diamine
Show/Hide
|
C20H17BrN6
|
1
|
| 1 |
IC50 = 8.1 nM
|
|
|
|
CP0283734
|
(E)-4-Methylamino-but-2-enoicacid[4-(3-chloro-4-fluorophenylamino)-3-cyano-7-(2-fluoroethoxy)-quinolin-6-yl]-amide
Show/Hide
|
C23H20ClF2N5O2
|
1
|
| 1 |
IC50 = 8.12 nM
|
|
|
|
CP0880582
|
4-(3'-fluoroanilino)-6,7-diethoxyquinazoline hydrochloride
Show/Hide
|
C18H19ClFN3O2
|
1
|
| 1 |
IC50 = 8.17 nM
|
|
|
|
CP0112580
|
N-[4-(3-methylanilino)pyrido[3,4-d]pyrimidin-6-yl]prop-2-enamide
Show/Hide
|
C17H15N5O
|
1
|
| 1 |
IC50 = 8.3 nM
|
|
|
|
CP0101536
|
(2E)-N-{4-[(3-bromophenyl)amino]quinazolin-6-yl}but-2-enamide
Show/Hide
|
C18H15BrN4O
|
1
|
| 1 |
IC50 = 8.7 nM
|
|
|
|
CP0544465
|
N,2-dimethyl-N-(4-methylsulfanylphenyl)quinazolin-4-amine
Show/Hide
|
C17H17N3S
|
1
|
| 1 |
IC50 = 8.7 nM
|
|
|
|
CP0061755
|
(2E)-N-{4-[(3-bromophenyl)amino]pyrido[3,4-d]pyrimidin-6-yl}-N'-[3-(morpholin-4-yl)propyl]but-2-enediamide
Show/Hide
|
C24H26BrN7O3
|
1
|
| 1 |
IC50 = 8.8 nM
|
|
|
|
CP0798678
|
N*4*-(3-Bromo-phenyl)-N*6*-[3-(4-methyl-piperazin-1-ylamino)-propyl]-pyrido[3,4-d]pyrimidine-4,6-diamine
Show/Hide
|
C21H27BrN8
|
1
|
| 1 |
IC50 = 8.9 nM
|
|
|
|
CP0876760
|
4-[3'fluoro-5'-(trifluoromethyl)anilino)]-6,7-diethoxyquinazoline hydrochloride
Show/Hide
|
C19H18ClF4N3O2
|
1
|
| 1 |
IC50 = 8.95 nM
|
|
|
|
CP0031182
|
Anilinoquinazoline deriv. 9
Show/Hide
|
C16H13ClFN3O2
|
2
|
| 1 |
IC50 = 9 nM
|
|
|
| 2 |
IC50 = 380 nM
|
|
|
|
CP0289028
|
6-(Methylamino)-4-(phenylamino)pyrido[3,4-d]pyrimidine
Show/Hide
|
C14H13N5
|
1
|
| 1 |
IC50 = 9 nM
|
|
|
|
CP0045249
|
4-N-(3-bromophenyl)-6-N-[3-(1H-imidazol-1-yl)propyl]pyrido[3,4-d]pyrimidine-4,6-diamine
Show/Hide
|
C19H18BrN7
|
1
|
| 1 |
IC50 = 9.1 nM
|
|
|
|
CP0876118
|
4-(2'-fluoroanilino)-6,7-diethoxyquinazoline hydrochloride
Show/Hide
|
C18H19ClFN3O2
|
1
|
| 1 |
IC50 = 9.31 nM
|
|
|
|
CP0385315
|
5-[(3-Bromophenyl)amino]-3-[[N-(carboxymethyl)-N-methylamino]methyl]pyrrolo[3,2-g]quinazoline ethyl ester
Show/Hide
|
C21H20BrN5O2
|
1
|
| 1 |
IC50 = 9.6 nM
|
|
|
|
CP0457105
|
5-[(3-Bromophenyl)amino]-3-[(4-morpholino)methyl]-pyrrolo[3,2-g]quinazoline
Show/Hide
|
C21H20BrN5O
|
1
|
| 1 |
IC50 = 9.6 nM
|
|
|
|
CP0214562
|
5-[(3-Bromophenyl)amino]-3-[(N,N-dimethylamino)-methyl]pyrrolo[3,2-g]quinazoline
Show/Hide
|
C19H18BrN5
|
1
|
| 1 |
IC50 = 9.7 nM
|
|
|
|
CP0208525
|
N-[4-(6-bromo-2,3-dihydroindol-1-yl)quinazolin-6-yl]prop-2-enamide
Show/Hide
|
C19H15BrN4O
|
1
|
| 1 |
IC50 = 9.9 nM
|
|
|
|
CP0195792
|
4-Anilinoquinazoline deriv. 49
Show/Hide
|
C15H12BrN3O
|
1
|
| 1 |
IC50 = 10 nM
|
|
|
|
CP0404067
|
4-(Benzylamino)quinazoline deriv. 40
Show/Hide
|
C17H17N3O2
|
1
|
| 1 |
IC50 = 10 nM
|
|
|
|
CP0183850
|
4-N-(3-bromophenyl)pyrido[4,3-d]pyrimidine-4,7-diamine
Show/Hide
|
C13H10BrN5
|
2
|
| 1 |
IC50 = 10 nM
|
|
|
| 2 |
IC50 = 110 nM
|
|
|
|
CP0536037
|
(6,7-Dimethoxy-quinazolin-4-yl)-(2-phenyl-cyclopropyl)-amine
Show/Hide
|
C19H19N3O2
|
1
|
| 1 |
IC50 = 10 nM
|
|
|
|
CP0534849
|
7-Methoxy-quinazoline
Show/Hide
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C9H8N2O
|
1
|
| 1 |
IC50 = 10 nM
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CP0401536
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N-(3-chloro-4-fluorophenyl)-7-methoxy-6-(2-morpholin-4-ylethoxy)quinazolin-4-amine
Show/Hide
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C21H22ClFN4O3
|
1
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| 1 |
IC50 = 10 nM
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CP0440985
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(3-Chloro-4-fluoro-phenyl)-{7-methoxy-6-[2-(4-methyl-piperazin-1-yl)-ethoxy]-quinazolin-4-yl}-amine
Show/Hide
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C22H25ClFN5O2
|
1
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| 1 |
IC50 = 10 nM
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CP0415603
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N-(4-methoxyphenyl)-5-methyl-N-propan-2-ylfuro[2,3-d]pyrimidin-4-amine
Show/Hide
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C17H19N3O2
|
1
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| 1 |
IC50 = 10.1 nM
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CP0516902
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N-(5-methoxynaphthalen-2-yl)-N,2-dimethylquinazolin-4-amine
Show/Hide
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C21H19N3O
|
1
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| 1 |
IC50 = 10.6 nM
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CP0263941
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4-N-(3-bromophenyl)-7-N,7-N-dimethylquinazoline-4,7-diamine
Show/Hide
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C16H15BrN4
|
1
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| 1 |
IC50 = 11 nM
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CP0497314
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N,N-dimethylquinazolin-7-amine
Show/Hide
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C10H11N3
|
1
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| 1 |
IC50 = 11 nM
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CP0894107
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(2R,3R)-ethyl 3-(4-(3-bromoanilino)quinazolin-6-ylcarbamoyl)oxirane-2-carboxylate
Show/Hide
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C18H13BrN4O4
|
2
|
| 1 |
IC50 = 11 nM
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| 2 |
IC50 = 145 nM
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CP0202617
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4-N-(3-bromophenyl)-7-N-ethylquinazoline-4,7-diamine
Show/Hide
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C16H15BrN4
|
1
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| 1 |
IC50 = 12 nM
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CP0364247
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methyl N-[4-(3-bromoanilino)quinazolin-6-yl]carbamate
Show/Hide
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C16H13BrN4O2
|
1
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| 1 |
IC50 = 12 nM
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CP0336766
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4-[(3-bromophenyl)amino]-6-methoxypyrido[3,4-d]pyrimidine
Show/Hide
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C14H11BrN4O
|
1
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| 1 |
IC50 = 12 nM
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CP0511864
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4-[(3-Bromophenyl)amino]-7-fluoropyrido[4,3-d]pyrimidine
Show/Hide
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C13H8BrFN4
|
1
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| 1 |
IC50 = 13 nM
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CP0123793
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5-[(3-Bromophenyl)amino]-1-methylpyrazolo[4,3-g]-quinazoline
Show/Hide
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C16H12BrN5
|
1
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| 1 |
IC50 = 13 nM
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CP0016821
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4-N-(3-bromophenyl)-6-N-methylpyrido[3,4-d]pyrimidine-4,6-diamine
Show/Hide
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C14H12BrN5
|
3
|
| 1 |
IC50 = 13 nM
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| 2 |
IC50 = 15 nM
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| 3 |
IC50 = 13000 nM
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CP0154477
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4-N-(3-bromophenyl)-6-N-(pyridin-3-ylmethyl)pyrido[3,4-d]pyrimidine-4,6-diamine
Show/Hide
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C19H15BrN6
|
1
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| 1 |
IC50 = 13 nM
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CP0110466
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N-(3-Bromophenyl)-6-methoxy-1H-pyrimido[4,5-b]indole-4-amine
Show/Hide
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C17H13BrN4O
|
1
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| 1 |
IC50 = 13 nM
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CP0336732
|
4-Anilinopyrido[3,4-d]pyrimidine 7
Show/Hide
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C17H14BrN5O
|
1
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| 1 |
IC50 = 13 nM
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CP0214563
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4-N-(3-bromophenyl)-7-N,7-N-dimethylpyrido[4,3-d]pyrimidine-4,7-diamine
Show/Hide
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C15H14BrN5
|
1
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| 1 |
IC50 = 14 nM
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CP0270886
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N-[4-(3-bromoanilino)quinazolin-7-yl]prop-2-enamide
Show/Hide
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C17H13BrN4O
|
1
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| 1 |
IC50 = 14 nM
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CP0088100
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(2E)-N-{4-[(3-chloro-4-fluorophenyl)amino]pyrido[3,4-d]pyrimidin-6-yl}-N'-[3-(morpholin-4-yl)propyl]but-2-enediamide
Show/Hide
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C24H25ClFN7O3
|
1
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| 1 |
IC50 = 14 nM
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CP0309591
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(2E)-N-{4-[(3-bromophenyl)amino]pyrido[3,4-d]pyrimidin-6-yl}-N'-[3-(1H-imidazol-1-yl)propyl]but-2-enediamide
Show/Hide
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C23H21BrN8O2
|
1
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| 1 |
IC50 = 14 nM
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CP0505143
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4-N-[3-(trifluoromethyl)phenyl]pyrido[4,3-d]pyrimidine-4,7-diamine
Show/Hide
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C14H10F3N5
|
1
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| 1 |
IC50 = 15 nM
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CP0404350
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N-(3-bromophenyl)-[1,3]dioxolo[4,5-g]quinazolin-8-amine
Show/Hide
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C15H10BrN3O2
|
1
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| 1 |
IC50 = 15 nM
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CP0276146
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N-(3-bromophenyl)-7-methoxy-6-nitroquinazolin-4-amine
Show/Hide
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C15H11BrN4O3
|
1
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| 1 |
IC50 = 15 nM
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CP0543738
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N-[3-chloro-4-[(3-fluorophenyl)methoxy]phenyl]-6,7-dimethoxyquinazolin-4-amine
Show/Hide
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C23H19ClFN3O3
|
1
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| 1 |
IC50 < 15 nM
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CP0396550
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N-(4-methoxyphenyl)-N,5-dimethylfuro[2,3-d]pyrimidin-4-amine
Show/Hide
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C15H15N3O2
|
1
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| 1 |
IC50 = 15.5 nM
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CP0332899
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4-N-(3-bromophenyl)pyrido[3,4-d]pyrimidine-4,6-diamine
Show/Hide
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C13H10BrN5
|
1
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| 1 |
IC50 = 16 nM
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CP0403718
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4-N-(3-bromophenyl)-7-N-methylpyrido[4,3-d]pyrimidine-4,7-diamine
Show/Hide
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C14H12BrN5
|
1
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| 1 |
IC50 = 16 nM
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CP0448952
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5-[(3-Bromophenyl)amino]-1-[2-(4-morpholino)ethyl]-pyrrolo[3,2-g]quinazoline
Show/Hide
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C22H22BrN5O
|
1
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| 1 |
IC50 = 16 nM
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CP0271485
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4-N-(3-bromophenyl)-6-N-[3-(dimethylamino)propyl]pyrido[3,4-d]pyrimidine-4,6-diamine
Show/Hide
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C18H21BrN6
|
1
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| 1 |
IC50 = 16 nM
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CP0041998
|
4-anilinoquinazoline deriv. 17
Show/Hide
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C18H15BrN4O
|
1
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| 1 |
IC50 = 16 nM
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CP0876761
|
4-(4'-fluoroanilino)-6,7-diethoxyquinazoline hydrochloride
Show/Hide
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C18H19ClFN3O2
|
1
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| 1 |
IC50 = 16 nM
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CP0308091
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(E)-4-[(4-Fluorobenzyl)methylamino]-but-2-enoic acid[4-(3-chloro-4-fluorophenylamino)-3-cyano-7-ethoxyquinoline-6-yl]amide
Show/Hide
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C30H26ClF2N5O2
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1
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| 1 |
IC50 = 16.52 nM
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CP0876122
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4-[(4'-fluorobenzyl)amino]-6,7-diethoxyquinazoline hydrochloride
Show/Hide
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C19H21ClFN3O2
|
1
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| 1 |
IC50 = 17 nM
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CP0455128
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4-[(3-Bromophenyl)amino]-6-chloropyrido[3,2-d]pyrimidine
Show/Hide
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C13H8BrClN4
|
1
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| 1 |
IC50 = 18 nM
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CP0097692
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N-[4-(3-bromo-4-fluoroanilino)pyrido[3,2-d]pyrimidin-6-yl]prop-2-enamide
Show/Hide
|
C16H11BrFN5O
|
1
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| 1 |
IC50 = 18 nM
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CP0106327
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N-[4-(3-chloro-4-fluoroanilino)pyrido[3,2-d]pyrimidin-6-yl]prop-2-enamide
Show/Hide
|
C16H11ClFN5O
|
1
|
| 1 |
IC50 = 18 nM
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CP0309365
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N-[4-(3-methylanilino)-7-[3-(4-methylpiperazin-1-yl)propoxy]quinazolin-6-yl]prop-2-enamide
Show/Hide
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C26H32N6O2
|
1
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| 1 |
IC50 = 18 nM
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CP0273874
|
4-N-(3-bromophenyl)-6-N-[4-(dimethylamino)butyl]pyrido[3,4-d]pyrimidine-4,6-diamine
Show/Hide
|
C19H23BrN6
|
1
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| 1 |
IC50 = 19 nM
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CP0183162
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(6,7-Dimethoxy-quinazolin-4-yl)-(3-ethynyl-phenyl)-amine
Show/Hide
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C18H15N3O2
|
1
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| 1 |
IC50 = 19 nM
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CP0169775
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4-N-(3-bromophenyl)-6-N-methylpyrido[3,2-d]pyrimidine-4,6-diamine
Show/Hide
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C14H12BrN5
|
1
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| 1 |
IC50 = 20 nM
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CP0005585
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3-((4-Methoxybenzyl)amino)-4-((3-chlorophenyl)amino)-1H-pyrazolo[3,4-d]pyrimidine
Show/Hide
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C19H17ClN6O
|
1
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| 1 |
IC50 = 20 nM
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CP0311142
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4-N-(3-methylphenyl)-6-N-[2-(morpholin-4-yl)ethyl]pyrido[3,4-d]pyrimidine-4,6-diamine
Show/Hide
|
C20H24N6O
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1
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| 1 |
IC50 = 20 nM
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CP0798077
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N-[4-(3-Bromo-phenylamino)-pyrido[3,4-d]pyrimidin-6-yl]-3-chloro-acrylamide
Show/Hide
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C16H11BrClN5O
|
1
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| 1 |
IC50 = 20 nM
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CP0910373
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4-[3'-fluoro-5'-(trifluoromethyl)anilino]-6,7-dimethoxyquinazoline hydrochloride
Show/Hide
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C17H14ClF4N3O2
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1
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| 1 |
IC50 = 20 nM
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CP0275262
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4-N-(3-bromophenyl)-6-N,6-N-dimethylpyrido[3,4-d]pyrimidine-4,6-diamine
Show/Hide
|
C15H14BrN5
|
1
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| 1 |
IC50 = 21 nM
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CP0285969
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N-[4-(3-bromoanilino)-7-(3-imidazol-1-ylpropoxy)quinazolin-6-yl]prop-2-enamide
Show/Hide
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C23H21BrN6O2
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1
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| 1 |
IC50 = 21 nM
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CP0184301
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(2E)-N-{4-[(3-bromophenyl)amino]pyrido[3,4-d]pyrimidin-6-yl}-N'-[3-(diethylamino)propyl]but-2-enediamide
Show/Hide
|
C24H28BrN7O2
|
1
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| 1 |
IC50 = 21 nM
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CP0007142
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N-[3-chloro-4-[(3-fluorophenyl)methoxy]phenyl]-6-[5-[(2-methylsulfonylethylamino)methyl]furan-2-yl]quinazolin-4-amine
Show/Hide
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C29H26ClFN4O4S
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3
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| 1 |
IC50 = 21 nM
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| 2 |
IC50 = 52 nM
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| 3 |
IC50 = 2685 nM
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CP0316778
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(E)-4-{[1-(2-Fluoroethyl)-1H-[1,2,3]triazol-4-ylmethyl]-amino}-but-2-enoic acid[4-(3-chloro-4-fluoro-phenylamino)-3-cyano-7-ethoxy-quinolin-6-yl]-amide
Show/Hide
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C27H25ClF2N8O2
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1
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| 1 |
IC50 = 21.97 nM
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CP0502450
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8-[(3-Bromophenyl)amino]-3-[2-(dimethylamino)ethyl]-3H-imidazo[4,5-g]quinazoline
Show/Hide
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C19H19BrN6
|
1
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| 1 |
IC50 = 22 nM
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CP0458855
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5-[(3-Bromophenyl)amino]-1-methylpyrrolo[3,2-g]-quinazoline
Show/Hide
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C17H13BrN4
|
1
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| 1 |
IC50 = 22 nM
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CP0212367
|
US8901140, 1
Show/Hide
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C32H31ClN6O3
|
1
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| 1 |
IC50 = 22 nM
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CP0081945
|
4-Anilino quinazoline deriv. 14
Show/Hide
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C14H10ClN3
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1
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| 1 |
IC50 = 23 nM
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CP0278985
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6-(Methylamino)-4-[(3-methylphenyl)amino]pyrido[3,4-d]pyrimidine
Show/Hide
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C15H15N5
|
1
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| 1 |
IC50 = 23 nM
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CP0283733
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(E)-4-[(2-Fluoroethyl)methylamino]-but-2-enoic acid[4-(3-chloro-4-fluorophenylamino)-3-cyano-7-ethoxyquinoline-6-yl]amide
Show/Hide
|
C25H24ClF2N5O2
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1
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| 1 |
IC50 = 23.02 nM
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CP0295299
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4-[(3-Bromophenyl)amino]-7-chloro-6-nitroquinazoline
Show/Hide
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C14H8BrClN4O2
|
1
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| 1 |
IC50 = 25 nM
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CP0153516
|
4-Anilino quinazoline deriv. 15
Show/Hide
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C14H10BrN3
|
1
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| 1 |
IC50 = 27 nM
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CP0506526
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6-[3-(dimethylamino)propoxy]-7-methoxy-N-(2-phenylcyclopropyl)quinazolin-4-amine
Show/Hide
|
C23H28N4O2
|
1
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| 1 |
IC50 = 27 nM
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CP0399606
|
1,3-benzodiazine
Show/Hide
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C8H6N2
|
1
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| 1 |
IC50 = 27 nM
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CP0095199
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2-{[2-({4-[(3-bromophenyl)amino]pyrido[3,4-d]pyrimidin-6-yl}amino)ethyl](methyl)amino}ethan-1-ol
Show/Hide
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C18H21BrN6O
|
1
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| 1 |
IC50 = 27 nM
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CP0258286
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N-[4-(3-methylanilino)-7-(3-morpholin-4-ylpropoxy)quinazolin-6-yl]prop-2-enamide
Show/Hide
|
C25H29N5O3
|
1
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| 1 |
IC50 = 27 nM
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CP0100411
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(2E)-N-[4-(3-Bromoanilino)pyrido[3,4-d]pyrimidin-6-yl]-2,4-pentadienamide
Show/Hide
|
C18H14BrN5O
|
1
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| 1 |
IC50 = 27 nM
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CP0448639
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N-[4-(3-bromoanilino)-6-nitroquinazolin-7-yl]acetamide
Show/Hide
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C16H12BrN5O3
|
1
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| 1 |
IC50 = 28 nM
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CP0151960
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4-N-(3-bromophenyl)-6-N-[3-(diethylamino)-2-hydroxypropyl]pyrido[3,4-d]pyrimidine-4,6-diamine
Show/Hide
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C20H25BrN6O
|
2
|
| 1 |
IC50 = 28 nM
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| 2 |
IC50 = 28000 nM
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CP0290384
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9-[(3-Bromophenyl)amino]-1H-imidazo[4,5-f]quinazoline
Show/Hide
|
C15H10BrN5
|
1
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| 1 |
IC50 = 29 nM
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CP0026347
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6,7-dimethoxy-N-phenylquinazolin-4-amine
Show/Hide
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C16H15N3O2
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2
|
| 1 |
IC50 = 29 nM
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| 2 |
IC50 = 4300 nM
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CP0492314
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7-Acetamido-4-[(3-bromophenyl)amino]pyrido[4,3-d]-pyrimidine
Show/Hide
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C15H12BrN5O
|
1
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| 1 |
IC50 = 29 nM
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CP0263950
|
4-Anilinoquinazoline deriv. 46
Show/Hide
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C15H12BrN3O
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2
|
| 1 |
IC50 = 30 nM
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| 2 |
IC50 = 348 nM
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CP0506174
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6-Methoxy-quinazoline
Show/Hide
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C9H8N2O
|
1
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| 1 |
IC50 = 30 nM
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CP0012033
|
4-(Phenylamino)pyrazolo[3,4-d]pyrimidine deriv. 23
Show/Hide
|
C17H12ClN5
|
1
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| 1 |
IC50 = 30 nM
|
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CP0036276
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4-[(3-chloro-4-fluorophenyl)amino]-6-[(1H-imidazol-4-ylmethyl)amino]quinoline-3-carbonitrile
Show/Hide
|
C20H14ClFN6
|
1
|
| 1 |
IC50 = 30 nM
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CP0466970
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N-(3-ethynylphenyl)-2,6-dimethylfuro[2,3-d]pyrimidin-4-amine
Show/Hide
|
C16H13N3O
|
1
|
| 1 |
IC50 = 30 nM
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CP0473161
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N-(3-chloro-4-fluorophenyl)-2,6-dimethylfuro[2,3-d]pyrimidin-4-amine
Show/Hide
|
C14H11ClFN3O
|
1
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| 1 |
IC50 = 30.2 nM
|
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CP0407458
|
N-[4-(3-bromoanilino)quinazolin-6-yl]-2-(4-fluorophenoxy)acetamide
Show/Hide
|
C22H16BrFN4O2
|
2
|
| 1 |
IC50 = 31 nM
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| 2 |
IC50 = 291 nM
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CP0799641
|
(6,7-Dimethoxy-quinazolin-4-yl)-(3-fluoro-phenyl)-amine hydrochloride
Show/Hide
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C16H15ClFN3O2
|
1
|
| 1 |
IC50 = 31.9 nM
|
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CP0263938
|
4-N-(3-bromophenyl)-6-N,6-N-dimethylpyrido[3,2-d]pyrimidine-4,6-diamine
Show/Hide
|
C15H14BrN5
|
1
|
| 1 |
IC50 = 32 nM
|
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CP0876794
|
4-(2'-fluoroanilino)-6,7-dimethoxyquinazoline hydrochloride
Show/Hide
|
C16H15ClFN3O2
|
1
|
| 1 |
IC50 = 32.2 nM
|
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CP0732267
|
N*4*-(3-Bromo-phenyl)-N*8*-methyl-benzo[4,5]thieno[3,2-d]pyrimidine-4,8-diamine; compound with ethanol
Show/Hide
|
C19H19BrN4OS
|
1
|
| 1 |
IC50 = 33 nM
|
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CP0897293
|
1-(7-Benzyl-2-methyl-5H-pyrrolo[3,2-d]pyrimidin-4-yl)-6-methoxy-1,2,3,4-tetrahydroquinoline hydrochloride
Show/Hide
|
C24H25ClN4O
|
1
|
| 1 |
IC50 = 33.6 nM
|
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CP0263939
|
4-[(3-Bromophenyl)-amino]pyrido[3,2-d]pyrimidine
Show/Hide
|
C13H9BrN4
|
1
|
| 1 |
IC50 = 34 nM
|
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CP0853171
|
(2S,3S)-Ethyl 3-(4-(3-Bromoanilino)quinazolin-6-ylcarbamoyl)oxirane-2-carboxylate
Show/Hide
|
C18H13BrN4O4
|
2
|
| 1 |
IC50 = 34 nM
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|
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| 2 |
IC50 = 68 nM
|
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CP0202616
|
4-[(3-Bromophenyl)-amino]pyrido[4,3-d]pyrimidine
Show/Hide
|
C13H9BrN4
|
1
|
| 1 |
IC50 = 35 nM
|
|
|
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CP0404127
|
2-[{2-[4-(3-Chloro-4-fluoro-phenylamino)-7-methoxy-quinazolin-6-yloxy]-ethyl}-(2-hydroxy-ethyl)-amino]-ethanol
Show/Hide
|
C21H24ClFN4O4
|
1
|
| 1 |
IC50 = 35 nM
|
|
|
|
CP0147754
|
(2E)-N-[4-(3-Bromoanilino)-6-quinazolinyl]-4,4,4-trifluoro-2-butenamide
Show/Hide
|
C18H12BrF3N4O
|
1
|
| 1 |
IC50 = 35 nM
|
|
|
|
CP0064501
|
4-N-(3-bromophenyl)-7-N-[2-(morpholin-4-yl)ethyl]pyrido[4,3-d]pyrimidine-4,7-diamine
Show/Hide
|
C19H21BrN6O
|
1
|
| 1 |
IC50 = 36 nM
|
|
|
|
CP0283068
|
US8901140, 3
Show/Hide
|
C32H31ClN6O4
|
1
|
| 1 |
IC50 = 36 nM
|
|
|
|
CP0496891
|
1-{4-[(3-chlorophenyl)amino-6-quinazolinyl}-3-(2-N,N-dimethylaminoethyl)triazene
Show/Hide
|
C18H20ClN7
|
1
|
| 1 |
IC50 = 37 nM
|
|
|
|
CP0511246
|
4-[(3-Bromophenyl)amino]-7-methoxypyrido[4,3-d]pyrimidine
Show/Hide
|
C14H11BrN4O
|
1
|
| 1 |
IC50 = 39 nM
|
|
|
|
CP0403963
|
4-N-(3-methylphenyl)pyrido[4,3-d]pyrimidine-4,7-diamine
Show/Hide
|
C14H13N5
|
1
|
| 1 |
IC50 = 40 nM
|
|
|
|
CP0506152
|
4-N-(3-nitrophenyl)pyrido[4,3-d]pyrimidine-4,7-diamine
Show/Hide
|
C13H10N6O2
|
1
|
| 1 |
IC50 = 40 nM
|
|
|
|
CP0169902
|
7-Acetamido-4-[(3-bromophenyl)amino]quinazoline
Show/Hide
|
C16H13BrN4O
|
1
|
| 1 |
IC50 = 40 nM
|
|
|
|
CP0276143
|
4-[(3-Bromophenyl)amino]-6-chloropyrido[3,4-d]pyrimidine
Show/Hide
|
C13H8BrClN4
|
1
|
| 1 |
IC50 = 40 nM
|
|
|
|
CP0003725
|
3-((4-Hydroxyphenyl)amino)-4-((3-chlorophenyl)amino)-1H-pyrazolo[3,4-d]pyrimidine
Show/Hide
|
C17H13ClN6O
|
1
|
| 1 |
IC50 = 40 nM
|
|
|
|
CP0084269
|
(5Z)-4-[(3-chloro-4-fluorophenyl)amino]-5-{[3-methyl-5-(morpholin-4-ylcarbonyl)-1H-pyrrol-2-yl]methylidene}-5H,6H,7H-pyrrolo[2,3-d]pyrimidin-6-one
Show/Hide
|
C23H20ClFN6O3
|
1
|
| 1 |
IC50 = 40 nM
|
|
|
|
CP0088175
|
5-{[(5Z)-4-[(3-chloro-4-fluorophenyl)amino]-6-oxo-5H,6H,7H-pyrrolo[2,3-d]pyrimidin-5-ylidene]methyl}-4-methyl-N-[2-(morpholin-4-yl)ethyl]-1H-pyrrole-2-carboxamide
Show/Hide
|
C25H25ClFN7O3
|
1
|
| 1 |
IC50 = 40 nM
|
|
|
|
CP0201108
|
5-{[(5Z)-4-[(3-ethynylphenyl)amino]-6-oxo-5H,6H,7H-pyrrolo[2,3-d]pyrimidin-5-ylidene]methyl}-4-methyl-N-[2-(morpholin-4-yl)ethyl]-1H-pyrrole-2-carboxamide
Show/Hide
|
C27H27N7O3
|
1
|
| 1 |
IC50 = 40 nM
|
|
|
|
CP0237040
|
6-N-(3-bromophenyl)-12-fluoro-8-thia-3,5-diazatricyclo[7.4.0.0^{2,7}]trideca-1(9),2(7),3,5,10,12-hexaene-6,11-diamine
Show/Hide
|
C16H10BrFN4S
|
1
|
| 1 |
IC50 = 42 nM
|
|
|
|
CP0294002
|
N-(3-ethynylphenyl)-6,7-dimethoxyquinolin-4-amine
Show/Hide
|
C19H16N2O2
|
1
|
| 1 |
IC50 = 42 nM
|
|
|
|
CP0399065
|
N-(4-methoxyphenyl)-2,6-dimethylfuro[2,3-d]pyrimidin-4-amine
Show/Hide
|
C15H15N3O2
|
1
|
| 1 |
IC50 = 42.2 nM
|
|
|
|
CP0230644
|
4-N-(3-bromophenyl)-6-N-[2-(dimethylamino)ethyl]pyrido[3,4-d]pyrimidine-4,6-diamine
Show/Hide
|
C17H19BrN6
|
2
|
| 1 |
IC50 = 43 nM
|
|
|
| 2 |
IC50 = 43000 nM
|
|
|
|
CP0333760
|
[(2S)-1-methoxy-3-(2-nitroimidazol-1-yl)propan-2-yl] 4-[(2-hydroxy-5-oxocyclopenta-1,3-dien-1-yl)methylideneamino]benzoate
Show/Hide
|
C20H18N4O7
|
1
|
| 1 |
IC50 = 43.478261 nM
|
|
|
|
CP0496236
|
8-[(3-Bromophenyl)amino]thiazolo[5,4-g]quinazoline
Show/Hide
|
C15H9BrN4S
|
1
|
| 1 |
IC50 = 44 nM
|
|
|
|
CP0374642
|
4-[(3-bromophenyl)-amino]-6-fluoropyrido[3,2-d]pyrimidine
Show/Hide
|
C13H8BrFN4
|
1
|
| 1 |
IC50 = 44 nM
|
|
|
|
CP0037739
|
4-Anilinopyrido[3,4-d]pyrimidine 8
Show/Hide
|
C17H14BrN5O
|
1
|
| 1 |
IC50 = 44 nM
|
|
|
|
CP0140205
|
BPI-2009
Show/Hide
|
C22H21N3O4
|
1
|
| 1 |
IC50 = 45 nM
|
|
|
|
CP0341521
|
N-(3-chloro-4-fluorophenyl)-2,5,8,11-tetraoxa-15,17-diazatricyclo[10.8.0.014,19]icosa-1(12),13,15,17,19-pentaen-18-amine
Show/Hide
|
C20H19ClFN3O4
|
1
|
| 1 |
IC50 = 45 nM
|
|
|
|
CP0283069
|
US8901140, 5
Show/Hide
|
C32H31ClN6O3
|
1
|
| 1 |
IC50 = 45 nM
|
|
|
|
CP0061738
|
4-N-(3-bromophenyl)-6-N-[2-(dimethylamino)ethyl]-6-N-methylpyrido[3,4-d]pyrimidine-4,6-diamine
Show/Hide
|
C18H21BrN6
|
1
|
| 1 |
IC50 = 46 nM
|
|
|
|
CP0247154
|
[(2R)-1-[(2-methylpropan-2-yl)oxy]-3-(2-nitroimidazol-1-yl)propan-2-yl] 4-[(2-hydroxy-5-oxocyclopenta-1,3-dien-1-yl)methylideneamino]benzoate
Show/Hide
|
C23H24N4O7
|
1
|
| 1 |
IC50 = 46.948357 nM
|
|
|
|
CP0464065
|
7-benzyl-4-(6-methoxy-3,4-dihydro-2H-quinolin-1-yl)-5H-pyrrolo[3,2-d]pyrimidin-2-amine
Show/Hide
|
C23H23N5O
|
1
|
| 1 |
IC50 = 47.1 nM
|
|
|
|
CP0878522
|
4-[(4'-fluorobenzyl)amino]-6,7-dimethoxyquinazoline hydrochloride
Show/Hide
|
C17H17ClFN3O2
|
1
|
| 1 |
IC50 = 47.7 nM
|
|
|
|
CP0516900
|
4-(6-methoxy-3,4-dihydro-2H-quinolin-1-yl)quinazoline
Show/Hide
|
C18H17N3O
|
1
|
| 1 |
IC50 = 48.9 nM
|
|
|
|
CP0377769
|
3-{4-[(3-bromophenyl)amino]-8H-pyrrolo[3,2-g]quinazolin-8-yl}propane-1,2-diol
Show/Hide
|
C19H17BrN4O2
|
1
|
| 1 |
IC50 = 49 nM
|
|
|
|
CP0503274
|
(3-Chloro-4-fluoro-phenyl)-[6-(3-dimethylamino-propoxy)-7-methoxy-quinazolin-4-yl]-amine
Show/Hide
|
C20H22ClFN4O2
|
1
|
| 1 |
IC50 = 49 nM
|
|
|
|
CP0301436
|
N-[3-[5-[2-[4-(4-ethylpiperazin-1-yl)anilino]pyrimidin-4-yl]imidazo[2,1-b][1,3]thiazol-6-yl]phenyl]-2,6-difluorobenzamide
Show/Hide
|
C34H30F2N8OS
|
1
|
| 1 |
IC50 = 50 nM
|
|
|
|
CP0140203
|
N-(3-bromophenyl)-2,5,8,11-tetraoxa-15,17-diazatricyclo[10.8.0.014,19]icosa-1(12),13,15,17,19-pentaen-18-amine
Show/Hide
|
C20H20BrN3O4
|
1
|
| 1 |
IC50 = 50 nM
|
|
|
|
CP0267821
|
N-(3-bromophenyl)-2,5,7,9,12-pentaoxa-16,18-diazatricyclo[11.8.0.015,20]henicosa-1(13),14,16,18,20-pentaen-19-amine
Show/Hide
|
C20H20BrN3O5
|
1
|
| 1 |
IC50 = 50 nM
|
|
|
|
CP0472536
|
N-[3-[2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]-7-oxopyrido[2,3-d]pyrimidin-8-yl]phenyl]prop-2-enamide
Show/Hide
|
C28H29N7O3
|
1
|
| 1 |
IC50 = 50 nM
|
|
|
|
CP0202615
|
4-[(3-Bromophenyl)-amino]pyrido[3,4-d]pyrimidine
Show/Hide
|
C13H9BrN4
|
1
|
| 1 |
IC50 = 51 nM
|
|
|
|
CP0207083
|
4-Anilinopyrido[3,4-d]pyrimidine 20
Show/Hide
|
C19H16BrN5O3
|
1
|
| 1 |
IC50 = 51 nM
|
|
|
|
CP0876375
|
4-(4'-fluoroanilino)-6,7-dimethoxyquinazoline hydrochloride
Show/Hide
|
C16H15ClFN3O2
|
1
|
| 1 |
IC50 = 51 nM
|
|
|
|
CP0177497
|
6-methoxy-7-(2-methoxyethoxy)-4-((1R,2S)-2-phenylcyclopropylamino)quinoline-3-carbonitrile
Show/Hide
|
C23H23N3O3
|
1
|
| 1 |
IC50 = 52.8 nM
|
|
|
|
CP0541007
|
4-N-(3-bromophenyl)-6-nitroquinazoline-4,7-diamine
Show/Hide
|
C14H10BrN5O2
|
1
|
| 1 |
IC50 = 53 nM
|
|
|
|
CP0381065
|
4-N-(3-bromophenyl)pyrido[3,2-d]pyrimidine-4,6-diamine
Show/Hide
|
C13H10BrN5
|
1
|
| 1 |
IC50 = 53 nM
|
|
|
|
CP0106249
|
N-[4-(3-chloroanilino)quinazolin-7-yl]prop-2-enamide
Show/Hide
|
C17H13ClN4O
|
1
|
| 1 |
IC50 = 53 nM
|
|
|
|
CP0711381
|
2-Hydroxy-4-[4-(2-nitro-vinyl)-phenoxysulfonyl]-benzoic acid
Show/Hide
|
C15H11NO8S
|
1
|
| 1 |
IC50 = 54 nM
|
|
|
|
CP0173070
|
[(2S)-1-(4-tert-butylphenoxy)-3-(2-nitroimidazol-1-yl)propan-2-yl] 4-[(2-hydroxy-5-oxocyclopenta-1,3-dien-1-yl)methylideneamino]benzoate
Show/Hide
|
C29H28N4O7
|
1
|
| 1 |
IC50 = 54.347826 nM
|
|
|
|
CP0263948
|
6-methoxy-N-phenylquinazolin-4-amine
Show/Hide
|
C15H13N3O
|
1
|
| 1 |
IC50 = 55 nM
|
|
|
|
CP0140204
|
N-(3-chlorophenyl)-2,5,8,11-tetraoxa-15,17-diazatricyclo[10.8.0.014,19]icosa-1(12),13,15,17,19-pentaen-18-amine
Show/Hide
|
C20H20ClN3O4
|
1
|
| 1 |
IC50 = 55 nM
|
|
|
|
CP0461019
|
4-(Benzylamino)quinazoline deriv. 39
Show/Hide
|
C16H15N3O2
|
1
|
| 1 |
IC50 = 56 nM
|
|
|
|
CP0263949
|
N-(3-fluorophenyl)quinazolin-4-amine
Show/Hide
|
C14H10FN3
|
1
|
| 1 |
IC50 = 56 nM
|
|
|
|
CP0405229
|
(3-Chloro-4-fluoro-phenyl)-[6-(3-diethylamino-propoxy)-7-methoxy-quinazolin-4-yl]-amine
Show/Hide
|
C22H26ClFN4O2
|
1
|
| 1 |
IC50 = 57 nM
|
|
|
|
CP0088500
|
(2E)-N-{4-[(3-bromophenyl)amino]pyrido[3,4-d]pyrimidin-6-yl}-N'-[3-(dimethylamino)propyl]but-2-enediamide
Show/Hide
|
C22H24BrN7O2
|
1
|
| 1 |
IC50 = 57 nM
|
|
|
|
CP0437006
|
4-(Benzylamino)quinazoline deriv. 34
Show/Hide
|
C16H15N3O
|
1
|
| 1 |
IC50 = 58 nM
|
|
|
|
CP0330268
|
(2E)-N-{4-[(3-bromophenyl)amino]quinazolin-6-yl}-N'-[3-(dimethylamino)propyl]but-2-enediamide
Show/Hide
|
C23H25BrN6O2
|
1
|
| 1 |
IC50 = 59 nM
|
|
|
|
CP0063821
|
(E)-N-(4-(3-chloro-4-fluorophenylamino)-3-cyano-7-ethoxyquinolin-6-yl)-4-(prop-2-ynylamino)but-2-enamide
Show/Hide
|
C25H21ClFN5O2
|
1
|
| 1 |
IC50 = 60.2 nM
|
|
|
|
CP0573151
|
(6-{2-[Bis-(2-methoxy-ethyl)-amino]-ethoxy}-7-methoxy-quinazolin-4-yl)-(3-chloro-4-fluoro-phenyl)-amine
Show/Hide
|
C23H28ClFN4O4
|
1
|
| 1 |
IC50 = 61 nM
|
|
|
|
CP0569632
|
4-(3-ethynylanilino)-6,7-dimethoxyquinoline-3-carbonitrile
Show/Hide
|
C20H15N3O2
|
1
|
| 1 |
IC50 = 61 nM
|
|
|
|
CP0194051
|
6-Substituted 4-Anilinoquinazoline 19
Show/Hide
|
C20H17BrN4O3
|
1
|
| 1 |
IC50 = 64 nM
|
|
|
|
CP0186561
|
(3-Chloro-4-fluoro-phenyl)-[6-(2-imidazol-1-yl-ethoxy)-7-methoxy-quinazolin-4-yl]-amine
Show/Hide
|
C20H17ClFN5O2
|
1
|
| 1 |
IC50 = 66 nM
|
|
|
|
CP0045281
|
AZD0530
Show/Hide
|
C27H32ClN5O5
|
1
|
| 1 |
IC50 = 66 nM
|
|
|
|
CP0520312
|
(2R)-1-[4-(3-chloro-4-fluoroanilino)-7-methoxyquinazolin-6-yl]oxy-3-morpholin-4-ylpropan-2-ol
Show/Hide
|
C22H24ClFN4O4
|
1
|
| 1 |
IC50 = 67 nM
|
|
|
|
CP0050737
|
4-N-(3-bromophenyl)-7-N-methyl-6-nitroquinazoline-4,7-diamine
Show/Hide
|
C15H12BrN5O2
|
1
|
| 1 |
IC50 = 68 nM
|
|
|
|
CP0201865
|
7-methoxy-4-((1R,2S)-2-phenylcyclopropylamino)-6-(3-(pyridin-3-yl)propoxy)quinoline-3-carbonitrile
Show/Hide
|
C28H26N4O2
|
1
|
| 1 |
IC50 = 68 nM
|
|
|
|
CP0383276
|
N-(4-methoxyphenyl)-N,2,6-trimethylfuro[2,3-d]pyrimidin-4-amine
Show/Hide
|
C16H17N3O2
|
1
|
| 1 |
IC50 = 68.2 nM
|
|
|
|
CP0466981
|
2-{2-[4-(3-Chloro-4-fluoro-phenylamino)-7-methoxy-quinazolin-6-yloxy]-ethylamino}-2-methyl-propane-1,3-diol
Show/Hide
|
C21H24ClFN4O4
|
1
|
| 1 |
IC50 = 69 nM
|
|
|
|
CP0518091
|
3-({7-aminopyrido[4,3-d]pyrimidin-4-yl}amino)phenol
Show/Hide
|
C13H11N5O
|
1
|
| 1 |
IC50 = 70 nM
|
|
|
|
CP0238723
|
4-(3-Bromo-phenoxy)-6,7-dimethoxy-quinazoline
Show/Hide
|
C16H13BrN2O3
|
1
|
| 1 |
IC50 = 70 nM
|
|
|
|
CP0526577
|
N-ethyl-N-(4-methoxyphenyl)-2,6-dimethylfuro[2,3-d]pyrimidin-4-amine
Show/Hide
|
C17H19N3O2
|
1
|
| 1 |
IC50 = 70.7 nM
|
|
|
|
CP0303871
|
2-{[2-({4-[(3-bromophenyl)amino]pyrido[3,4-d]pyrimidin-6-yl}amino)ethyl](2-hydroxyethyl)amino}ethan-1-ol
Show/Hide
|
C19H23BrN6O2
|
1
|
| 1 |
IC50 = 71 nM
|
|
|
|
CP0495443
|
(3-Chloro-4-fluoro-phenyl)-[7-methoxy-6-(3-pyrrolidin-1-yl-propoxy)-quinazolin-4-yl]-amine
Show/Hide
|
C22H24ClFN4O2
|
1
|
| 1 |
IC50 = 71 nM
|
|
|
|
CP0542856
|
1-{4-[(3-chlorophenyl)amino-6-quinazolinyl}-3-{2-[N-(2-chloroethyl)-N-benzylethylenamine]}triazene
Show/Hide
|
C25H25Cl2N7
|
1
|
| 1 |
IC50 = 71 nM
|
|
|
|
CP0510836
|
N-(4-methoxyphenyl)-2,6-dimethyl-N-propylfuro[2,3-d]pyrimidin-4-amine
Show/Hide
|
C18H21N3O2
|
1
|
| 1 |
IC50 = 73.3 nM
|
|
|
|
CP0407459
|
N-[4-(3-bromoanilino)quinazolin-6-yl]-2-phenoxyacetamide
Show/Hide
|
C22H17BrN4O2
|
2
|
| 1 |
IC50 = 76 nM
|
|
|
| 2 |
IC50 = 292 nM
|
|
|
|
CP0922327
|
(3-Bromo-phenyl)-[1-(3-morpholin-4-yl-propyl)-1H-pyrazolo[4,3-g]quinazolin-5-yl]-amine
Show/Hide
|
C22H23BrN6O
|
1
|
| 1 |
IC50 = 77 nM
|
|
|
|
CP0155380
|
(2E)-N-[4-(3-Bromoanilino)pyrido[3,4-d]pyrimidin-6-yl]-3-phenyl-2-propenamide
Show/Hide
|
C22H16BrN5O
|
1
|
| 1 |
IC50 = 77 nM
|
|
|
|
CP0073604
|
N-[4-(3-bromoanilino)quinazolin-6-yl]-2-(2,3,4,5,6-pentafluorophenoxy)acetamide
Show/Hide
|
C22H12BrF5N4O2
|
2
|
| 1 |
IC50 = 78 nM
|
|
|
| 2 |
IC50 = 84 nM
|
|
|
|
CP0479790
|
(3-Chloro-4-fluoro-phenyl)-[7-methoxy-6-(3-piperidin-1-yl-propoxy)-quinazolin-4-yl]-amine
Show/Hide
|
C23H26ClFN4O2
|
1
|
| 1 |
IC50 = 79 nM
|
|
|
|
CP0263951
|
4-Anilino quinazoline deriv. 16
Show/Hide
|
C14H10IN3
|
1
|
| 1 |
IC50 = 80 nM
|
|
|
|
CP0353028
|
5-[(3-Bromophenyl)amino]-3-[(N,N,N-trimethylethylenediamino)methyl]pyrrolo[3,2-g]quinazoline
Show/Hide
|
C22H25BrN6
|
1
|
| 1 |
IC50 = 81 nM
|
|
|
|
CP0858674
|
N-(4-Methoxyphenyl)-N,2,6-trimethylfuro[2,3-d]pyrimidin-4-amine hydrochloride
Show/Hide
|
C16H18ClN3O2
|
1
|
| 1 |
IC50 = 82.3 nM
|
|
|
|
CP0393128
|
Acetic acid 7-methoxy-4-(2-phenyl-cyclopropylamino)-quinazolin-6-yl ester
Show/Hide
|
C20H19N3O3
|
1
|
| 1 |
IC50 = 84 nM
|
|
|
|
CP0307523
|
4-N-(3-bromophenyl)-6-N,6-N-dimethylquinazoline-4,6-diamine
Show/Hide
|
C16H15BrN4
|
1
|
| 1 |
IC50 = 84 nM
|
|
|
|
CP0447221
|
N-(4-methoxyphenyl)-2,6-dimethyl-N-propan-2-ylfuro[2,3-d]pyrimidin-4-amine
Show/Hide
|
C18H21N3O2
|
1
|
| 1 |
IC50 = 84.4 nM
|
|
|
|
CP0756301
|
N*4*-(3-Bromo-phenyl)-N*7*-ethyl-8-fluoro-benzo[4,5]thieno[3,2-d]pyrimidine-4,7-diamine; compound with ethanol
Show/Hide
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C20H20BrFN4OS
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1
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| 1 |
IC50 = 85 nM
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CP0063420
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6-N-(3-bromophenyl)-8-thia-3,5-diazatricyclo[7.4.0.0^{2,7}]trideca-1(9),2(7),3,5,10,12-hexaene-6,12-diamine
Show/Hide
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C16H11BrN4S
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1
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| 1 |
IC50 = 86 nM
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CP0500997
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(3-Chloro-4-fluoro-phenyl)-[7-methoxy-6-(2-pyrrolidin-1-yl-ethoxy)-quinazolin-4-yl]-amine
Show/Hide
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C21H22ClFN4O2
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1
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| 1 |
IC50 = 87 nM
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CP0266600
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N-[4-(3-chloro-4-fluoroanilino)-7-(3-morpholin-4-ylpropoxy)pyrido[3,2-d]pyrimidin-6-yl]-N-methylprop-2-enamide
Show/Hide
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C24H26ClFN6O3
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1
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| 1 |
IC50 = 88 nM
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CP0415640
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4-N-(4-bromophenyl)pyrido[4,3-d]pyrimidine-4,7-diamine
Show/Hide
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C13H10BrN5
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1
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| 1 |
IC50 = 90 nM
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CP0352062
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N-[4-(3-methylanilino)quinazolin-7-yl]prop-2-enamide
Show/Hide
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C18H16N4O
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1
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| 1 |
IC50 = 90 nM
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CP0177492
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6,7-dimethoxy-4-((1R,2S)-2-phenylcyclopropylamino)quinoline-3-carbonitrile
Show/Hide
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C21H19N3O2
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1
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| 1 |
IC50 = 90 nM
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CP0289874
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4-(3-Bromophenylamino)-6,7-dimethoxyquinoline-3-carbonitrile
Show/Hide
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C18H14BrN3O2
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1
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| 1 |
IC50 = 90 nM
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CP0480461
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N-(1H-indol-4-yl)-2,6-dimethylfuro[2,3-d]pyrimidin-4-amine
Show/Hide
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C16H14N4O
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1
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| 1 |
IC50 = 90.2 nM
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CP0379500
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N-(3,4-dimethoxyphenyl)-N,2,6-trimethylfuro[2,3-d]pyrimidin-4-amine
Show/Hide
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C17H19N3O3
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1
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| 1 |
IC50 = 90.3 nM
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CP0467751
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N-ethyl-N-(4-methoxyphenyl)-5-methylfuro[2,3-d]pyrimidin-4-amine
Show/Hide
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C16H17N3O2
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1
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| 1 |
IC50 = 92.5 nM
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CP0740125
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(3-Bromo-phenyl)-(5H-pyrimido[5,4-b]indol-4-yl)-amine hydrochloride
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C16H12BrClN4
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1
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| 1 |
IC50 = 93 nM
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CP0521963
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(3-Chloro-4-fluoro-phenyl)-[6-(2-diethylamino-ethoxy)-7-methoxy-quinazolin-4-yl]-amine
Show/Hide
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C21H24ClFN4O2
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1
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| 1 |
IC50 = 93 nM
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CP0531565
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(2S)-1-[4-(3-chloro-4-fluoroanilino)-7-methoxyquinazolin-6-yl]oxy-3-morpholin-4-ylpropan-2-ol
Show/Hide
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C22H24ClFN4O4
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1
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| 1 |
IC50 = 95 nM
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CP0077454
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6-N-(3-methylphenyl)-8-thia-3,5-diazatricyclo[7.4.0.0^{2,7}]trideca-1(9),2(7),3,5,10,12-hexaene-6,12-diamine
Show/Hide
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C17H14N4S
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1
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| 1 |
IC50 = 98 nM
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CP0448908
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(3-Chloro-4-fluoro-phenyl)-[7-methoxy-6-(2-piperidin-1-yl-ethoxy)-quinazolin-4-yl]-amine
Show/Hide
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C22H24ClFN4O2
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1
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| 1 |
IC50 = 98 nM
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CP0263947
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4-N-phenylquinazoline-4,7-diamine
Show/Hide
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C14H12N4
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1
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| 1 |
IC50 = 100 nM
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CP0497893
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7-Acetamido-4-[(phenylmethyl)amino]pyrido[4,3-d]pyrimidine
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C16H15N5O
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1
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| 1 |
IC50 = 100 nM
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CP0394182
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6-[2-(tert-butylamino)ethoxy]-N-(3-chloro-4-fluorophenyl)-7-methoxyquinazolin-4-amine
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C21H24ClFN4O2
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1
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| 1 |
IC50 = 100 nM
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CP0062561
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(5Z)-4-[(1-benzyl-1H-indazol-5-yl)amino]-5-{[3-methyl-5-(morpholin-4-ylcarbonyl)-1H-pyrrol-2-yl]methylidene}-5H,6H,7H-pyrrolo[2,3-d]pyrimidin-6-one
Show/Hide
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C31H28N8O3
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1
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| 1 |
IC50 = 100 nM
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CP0206231
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(5Z)-4-[(1-benzyl-1H-indol-5-yl)amino]-5-{[3-methyl-5-(morpholin-4-ylcarbonyl)-1H-pyrrol-2-yl]methylidene}-5H,6H,7H-pyrrolo[2,3-d]pyrimidin-6-one
Show/Hide
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C32H29N7O3
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1
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| 1 |
IC50 = 100 nM
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CP0217755
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(5Z)-4-[(3-chloro-4-fluorophenyl)amino]-5-({3-methyl-5-[(4-methylpiperazin-1-yl)carbonyl]-1H-pyrrol-2-yl}methylidene)-5H,6H,7H-pyrrolo[2,3-d]pyrimidin-6-one
Show/Hide
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C24H23ClFN7O2
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1
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| 1 |
IC50 = 100 nM
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CP0298448
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4-[(3-Bromophenyl)amino]-6-(4-methyl-1-piperazinyl)-pyrido[3,4-d]pyrimidine
Show/Hide
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C18H19BrN6
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1
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| 1 |
IC50 = 102 nM
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CP0431419
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N,2,6-trimethyl-N-(4-propan-2-yloxyphenyl)furo[2,3-d]pyrimidin-4-amine
Show/Hide
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C18H21N3O2
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1
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| 1 |
IC50 = 102.2 nM
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CP0380834
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N-(4-chlorophenyl)-2,6-dimethylfuro[2,3-d]pyrimidin-4-amine
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C14H12ClN3O
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1
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| 1 |
IC50 = 102.3 nM
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CP0488682
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4-(5-methoxy-2,3-dihydroindol-1-yl)-2,6-dimethylfuro[2,3-d]pyrimidine
Show/Hide
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C17H17N3O2
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1
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| 1 |
IC50 = 103.2 nM
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CP0537500
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4-Anilinoquinazoline deriv. 51
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C14H11BrN4
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1
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| 1 |
IC50 = 105 nM
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CP0529897
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N-(3-bromophenyl)-6,7-dibutoxyquinazolin-4-amine
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C22H26BrN3O2
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1
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| 1 |
IC50 = 105 nM
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CP0115018
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N-[4-(3-bromoanilino)pyrido[4,3-d]pyrimidin-7-yl]prop-2-enamide
Show/Hide
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C16H12BrN5O
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1
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| 1 |
IC50 = 108 nM
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CP0194067
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3-(Dimethylamino)propyl (2E)-4-{[4-(3-Bromoanilino)-6-quinazolinyl]amino}-4-oxo-2-butenoate
Show/Hide
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C23H24BrN5O3
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1
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| 1 |
IC50 = 108 nM
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CP0467427
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N-(3,5-dibromophenyl)-6,7-dimethoxyquinazolin-4-amine
Show/Hide
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C16H13Br2N3O2
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1
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| 1 |
IC50 = 113 nM
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CP0421245
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2,6-dimethyl-N-phenylfuro[2,3-d]pyrimidin-4-amine
Show/Hide
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C14H13N3O
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1
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| 1 |
IC50 = 113.2 nM
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CP0258410
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N-[4-(3-chloro-4-fluoroanilino)-7-[(E)-4-morpholin-4-ylbut-1-enyl]pyrido[3,2-d]pyrimidin-6-yl]prop-2-enamide
Show/Hide
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C24H24ClFN6O2
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1
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| 1 |
IC50 = 119 nM
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CP0410109
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4-N-(3-chlorophenyl)pyrido[4,3-d]pyrimidine-4,7-diamine
Show/Hide
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C13H10ClN5
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1
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| 1 |
IC50 = 120 nM
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CP0150469
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(3-Chloro-phenyl)-(6,7,8,9-tetrahydro-5H-pyrimido[4,5-b]indol-4-yl)-amine
Show/Hide
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C16H15ClN4
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1
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| 1 |
IC50 = 120 nM
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CP0469373
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7-methoxy-N-phenylquinazolin-4-amine
Show/Hide
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C15H13N3O
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1
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| 1 |
IC50 = 120 nM
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CP0535729
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N,N-dimethylquinazolin-6-amine
Show/Hide
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C10H11N3
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1
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| 1 |
IC50 = 120 nM
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CP0183314
|
6-Substituted 4-Anilinoquinazoline 15
Show/Hide
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C18H13BrN4O
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1
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| 1 |
IC50 = 120 nM
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CP0510837
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2,6-dimethyl-N-[4-(trifluoromethyl)phenyl]furo[2,3-d]pyrimidin-4-amine
Show/Hide
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C15H12F3N3O
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1
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| 1 |
IC50 = 122.1 nM
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CP0344106
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4-[(3-Bromophenyl)amino]-6-fluoropyrido[3,4-d]pyrimidine
Show/Hide
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C13H8BrFN4
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1
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| 1 |
IC50 = 124 nM
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CP0536128
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N-(2-bromophenyl)-6,7-dimethoxyquinazolin-4-amine
Show/Hide
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C16H14BrN3O2
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1
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| 1 |
IC50 = 128 nM
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CP0521933
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4-N-(3-methoxyphenyl)pyrido[4,3-d]pyrimidine-4,7-diamine
Show/Hide
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C14H13N5O
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1
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| 1 |
IC50 = 130 nM
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CP0137245
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2-[({4-[(3-bromophenyl)amino]-8H-pyrrolo[3,2-g]quinazolin-6-yl}methyl)(2-hydroxyethyl)amino]ethan-1-ol
Show/Hide
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C21H22BrN5O2
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1
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| 1 |
IC50 = 135 nM
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CP0391257
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4-Anilinoquinazoline deriv. 43
Show/Hide
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C15H12BrN3O
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1
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| 1 |
IC50 = 139 nM
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CP0664046
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Lapatinib ditosylate
Show/Hide
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C43H44ClFN4O11S3
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1
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| 1 |
IC50 = 140 nM
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CP0424965
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5-[(3-Bromophenyl)amino]-1-[2-(N,N-dimethylamino)-ethyl]pyrrolo[3,2-g]quinazoline
Show/Hide
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C20H20BrN5
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1
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| 1 |
IC50 = 145 nM
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CP0383277
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2,6-dimethyl-N-naphthalen-1-ylfuro[2,3-d]pyrimidin-4-amine
Show/Hide
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C18H15N3O
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1
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| 1 |
IC50 = 145.2 nM
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CP0508568
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4-N-phenyl-9H-pyrimido[4,5-b]indole-2,4-diamine
Show/Hide
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C16H13N5
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1
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| 1 |
IC50 = 147 nM
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CP0012034
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3-((3-Chlorophenyl)amino)-4-((3-methylphenyl)amino)-1H-pyrazolo[3,4-d]pyrimidine
Show/Hide
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C18H15ClN6
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1
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| 1 |
IC50 = 150 nM
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CP0286969
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N-(3-bromophenyl)-6,7-dimethoxy-N-methylquinazolin-4-amine
Show/Hide
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C17H16BrN3O2
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1
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| 1 |
IC50 = 152 nM
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CP0295148
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4-Anilinopyrido[3,4-d]pyrimidine 22
Show/Hide
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C23H25BrN6O2
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1
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| 1 |
IC50 = 156 nM
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CP0360710
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4-[(3-chloro-4-fluorophenyl)amino]-8-acetyl-6-[(1H-imidazol-4-ylmethyl)amino]quinoline-3-carbonitrile
Show/Hide
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C22H16ClFN6O
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1
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| 1 |
IC50 = 156 nM
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CP0364246
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4-N-(3-bromophenyl)-7-N,7-N-dimethylquinazoline-4,6,7-triamine
Show/Hide
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C16H16BrN5
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1
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| 1 |
IC50 = 159 nM
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CP0388586
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N-(2,4-dimethoxyphenyl)-N,2,6-trimethylfuro[2,3-d]pyrimidin-4-amine
Show/Hide
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C17H19N3O3
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1
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| 1 |
IC50 = 162.3 nM
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CP0910286
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7-Benzyl-4-(5-methoxyindolin-1-yl)-2-methyl-5H-pyrrolo[3,2-d]pyrimidine hydrochloride
Show/Hide
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C23H23ClN4O
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1
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| 1 |
IC50 = 167.1 nM
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CP0392726
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(6,7-Dimethoxy-quinazolin-4-yl)-(3-methyl-benzyl)-amine
Show/Hide
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C18H19N3O2
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1
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| 1 |
IC50 = 170 nM
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CP0094385
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Benzothieno[3,2-d]pyrimidine deriv. 53
Show/Hide
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C16H10BrN3S
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1
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| 1 |
IC50 = 170 nM
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CP0438056
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(3-Bromo-phenyl)-(6,7-dimethoxy-quinolin-4-yl)-amine
Show/Hide
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C17H15BrN2O2
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2
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| 1 |
IC50 = 170 nM
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| 2 |
IC50 = 370 nM
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CP0002211
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N-[2-(diethylamino)ethyl]-5-[(Z)-(5-fluoro-2-oxo-1H-indol-3-ylidene)methyl]-2,4-dimethyl-1H-pyrrole-3-carboxamide
Show/Hide
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C22H27FN4O2
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1
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| 1 |
IC50 = 172.1 nM
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CP0177500
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6-methoxy-4-((1R,2S)-2-phenylcyclopropylamino)-7-(3-(pyridin-3-yl)propoxy)quinoline-3-carbonitrile
Show/Hide
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C28H26N4O2
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1
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| 1 |
IC50 = 173 nM
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CP0568871
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(3R,4R)-5,5-difluoro-4-methoxy-1-[4-[[8-[(2R,3S)-2-methyl-3-(methylsulfonylmethyl)azetidin-1-yl]-5-propan-2-ylisoquinolin-3-yl]amino]pyrimidin-2-yl]piperidin-3-ol
Show/Hide
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C28H36F2N6O4S
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1
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| 1 |
IC50 = 191 nM
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CP0441551
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5-[(3-Bromophenyl)amino]-1-[2-(4-morpholino)ethyl]-pyrazolo[4,3-g]quinazoline
Show/Hide
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C21H21BrN6O
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1
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| 1 |
IC50 = 192 nM
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CP0308933
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(2E)-N-{4-[(3-bromophenyl)amino]pyrido[3,4-d]pyrimidin-6-yl}-N'-[3-(dimethylamino)propyl]-N''-methylbut-2-enediamide
Show/Hide
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C23H26BrN7O2
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1
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| 1 |
IC50 = 193 nM
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CP0190282
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6-Substituted 4-Anilinoquinazoline 23
Show/Hide
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C24H26BrN5O2
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1
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| 1 |
IC50 = 194 nM
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CP0295032
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N-[4-(3-bromoanilino)-7-[3-(diethylamino)propylsulfanyl]quinazolin-6-yl]prop-2-enamide
Show/Hide
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C24H28BrN5OS
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1
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| 1 |
IC50 = 196 nM
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CP0535111
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4-(Benzylamino)quinazoline deriv. 31
Show/Hide
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C16H15N3O
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1
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| 1 |
IC50 = 200 nM
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CP0505388
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(6,7-Dimethoxy-quinazolin-4-yl)-isoquinolin-1-yl-amine
Show/Hide
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C19H16N4O2
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1
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| 1 |
IC50 = 200 nM
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CP0000329
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3-((3-Methoxybenzyl)amino)-4-((3-chlorophenyl)amino)-1H-pyrazolo[3,4-d]pyrimidine
Show/Hide
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C19H17ClN6O
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1
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| 1 |
IC50 = 200 nM
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CP0041166
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5-{[(5Z)-4-[(1-benzyl-1H-indol-5-yl)amino]-6-oxo-5H,6H,7H-pyrrolo[2,3-d]pyrimidin-5-ylidene]methyl}-4-methyl-N-[2-(morpholin-4-yl)ethyl]-1H-pyrrole-2-carboxamide
Show/Hide
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C34H34N8O3
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1
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| 1 |
IC50 = 200 nM
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CP0063852
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(5Z)-4-[(3-chloro-4-fluorophenyl)amino]-5-({5-[(4-ethylpiperazin-1-yl)carbonyl]-3-methyl-1H-pyrrol-2-yl}methylidene)-5H,6H,7H-pyrrolo[2,3-d]pyrimidin-6-one
Show/Hide
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C25H25ClFN7O2
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1
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| 1 |
IC50 = 200 nM
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CP0357546
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5-{[(5Z)-4-[(3-chloro-4-fluorophenyl)amino]-6-oxo-5H,6H,7H-pyrrolo[2,3-d]pyrimidin-5-ylidene]methyl}-N-[2-(diethylamino)ethyl]-4-methyl-1H-pyrrole-2-carboxamide
Show/Hide
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C25H27ClFN7O2
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1
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| 1 |
IC50 = 200 nM
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CP0190702
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Anilinoquinazoline, 4c
Show/Hide
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C14H11ClN4
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1
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| 1 |
IC50 = 200 nM
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CP0275218
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4-N-(3-bromophenyl)-6-[(2,4-dichlorophenyl)methyl]-7H-pyrrolo[2,3-d]pyrimidine-2,4-diamine
Show/Hide
|
C19H14BrCl2N5
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1
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| 1 |
IC50 = 200 nM
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CP0535215
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N-(4-chloro-2-fluorophenyl)-6,7-dimethoxyphthalazin-1-amine
Show/Hide
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C16H13ClFN3O2
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1
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| 1 |
IC50 = 200 nM
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CP0480517
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8-[(3-Bromophenyl)amino]-9-chloro-3-[2-(dimethylamino)ethyl]-3H-imidazo[4,5-g]quinazoline
Show/Hide
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C19H18BrClN6
|
1
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| 1 |
IC50 = 203 nM
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CP0204110
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N-[3-[5-[2-[4-[2-(dimethylamino)ethyl]anilino]pyrimidin-4-yl]imidazo[2,1-b][1,3]thiazol-6-yl]phenyl]-2,6-difluorobenzamide
Show/Hide
|
C32H27F2N7OS
|
1
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| 1 |
IC50 = 220 nM
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CP0432230
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N-(2,3-dihydro-1-benzofuran-5-yl)-N,2,6-trimethylfuro[2,3-d]pyrimidin-4-amine
Show/Hide
|
C17H17N3O2
|
1
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| 1 |
IC50 = 226.4 nM
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CP0322883
|
3-({4-[(3-bromophenyl)amino]pyrido[4,3-d]pyrimidin-7-yl}amino)propane-1,2-diol
Show/Hide
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C16H16BrN5O2
|
1
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| 1 |
IC50 = 227 nM
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CP0520197
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4-N-[(2-aminophenyl)methyl]pyrido[4,3-d]pyrimidine-4,7-diamine
Show/Hide
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C14H14N6
|
1
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| 1 |
IC50 = 230 nM
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CP0460856
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5-[(3-Bromophenyl)amino]-1-[3-(N,N-dimethylamino)-propyl]pyrrolo[3,2-g]quinazoline
Show/Hide
|
C21H22BrN5
|
1
|
| 1 |
IC50 = 230 nM
|
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CP0221154
|
2-{[3-({4-[(3-bromophenyl)amino]pyrido[3,4-d]pyrimidin-6-yl}amino)propyl](2-hydroxyethyl)amino}ethan-1-ol
Show/Hide
|
C20H25BrN6O2
|
1
|
| 1 |
IC50 = 230 nM
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CP0177491
|
7-(4-(morpholinomethyl)phenyl)-4-((1R,2S)-2-phenylcyclopropylamino)quinoline-3-carbonitrile
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C30H28N4O
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1
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| 1 |
IC50 = 234 nM
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CP0543938
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4-N-(2-bromophenyl)pyrido[4,3-d]pyrimidine-4,7-diamine
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C13H10BrN5
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1
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| 1 |
IC50 = 240 nM
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CP0096083
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4-N-(3-bromophenyl)-6-[(2,5-dimethoxyphenyl)methyl]-7H-pyrrolo[2,3-d]pyrimidine-2,4-diamine
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C21H20BrN5O2
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3
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| 1 |
IC50 = 240 nM
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| 2 |
IC50 = 12600 nM
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| 3 |
IC50 = 12620 nM
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CP0488132
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4-N-phenylpyrido[4,3-d]pyrimidine-4,7-diamine
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C13H11N5
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1
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| 1 |
IC50 = 250 nM
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CP0011492
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3,4-Bis((3-chlorophenyl)amino)-1H-pyrazolo[3,4-d]pyrimidine
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C17H12Cl2N6
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1
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| 1 |
IC50 = 250 nM
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CP0226749
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4-(3-chloro-4-(3-fluorobenzyloxy)phenylamino)-3-methyl-N-(2-(4-methylpiperazin-1-yl)ethyl)-1H-pyrrolo[3,2-d]pyridazine-2-carboxamide
Show/Hide
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C28H31ClFN7O2
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1
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| 1 |
IC50 = 257 nM
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CP0504668
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4-N-(3-iodophenyl)pyrido[4,3-d]pyrimidine-4,7-diamine
Show/Hide
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C13H10IN5
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1
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| 1 |
IC50 = 260 nM
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CP0039761
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5-[(3-Bromophenyl)amino]-1-[2-(N,N-dimethylamino)ethyl]pyrazolo[4,3-g]quinazoline
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C19H19BrN6
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1
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| 1 |
IC50 = 262 nM
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CP0288737
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4-[(3-bromophenyl)amino]-7-methoxypyrido[2,3-d]pyrimidine
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C14H11BrN4O
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1
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| 1 |
IC50 = 263 nM
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CP0281175
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N-[4-(3-chloro-4-fluoroanilino)-7-[3-(4-methylpiperazin-1-yl)propoxy]pyrido[3,2-d]pyrimidin-6-yl]prop-2-enamide
Show/Hide
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C24H27ClFN7O2
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1
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| 1 |
IC50 = 264 nM
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CP0509125
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6-[(3-Bromophenyl)amino]-1H-imidazo[4,5-h]quinazoline
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C15H10BrN5
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1
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| 1 |
IC50 = 272 nM
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CP0548535
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N-(4-methoxyphenyl)-5-methylfuro[2,3-d]pyrimidin-4-amine
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C14H13N3O2
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1
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| 1 |
IC50 = 283.1 nM
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CP0312514
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N-[4-(3-chloro-4-fluoroanilino)-7-methoxypyrido[3,2-d]pyrimidin-6-yl]prop-2-enamide
Show/Hide
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C17H13ClFN5O2
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1
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| 1 |
IC50 = 291 nM
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CP0398717
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N-(1,3-benzodioxol-5-yl)-N,2,6-trimethylfuro[2,3-d]pyrimidin-4-amine
Show/Hide
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C16H15N3O3
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1
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| 1 |
IC50 = 298.2 nM
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CP0102630
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(3-Chloro-phenyl)-(5,6-dimethyl-7H-pyrrolo[2,3-d]pyrimidin-4-yl)-amine
Show/Hide
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C14H13ClN4
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1
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| 1 |
IC50 = 300 nM
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CP0504005
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7-methoxy-6-(2-morpholin-4-ylethoxy)-N-(2-phenylcyclopropyl)quinazolin-4-amine
Show/Hide
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C24H28N4O3
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1
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| 1 |
IC50 = 300 nM
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CP0217745
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(5Z)-4-[(3-chloro-4-fluorophenyl)amino]-5-[(3,5-dimethyl-1H-pyrrol-2-yl)methylidene]-5H,6H,7H-pyrrolo[2,3-d]pyrimidin-6-one
Show/Hide
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C19H15ClFN5O
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1
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| 1 |
IC50 = 300 nM
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CP0410666
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4-N-(3-bromophenyl)-6-(2-pyridin-2-ylethyl)-7H-pyrrolo[2,3-d]pyrimidine-2,4-diamine
Show/Hide
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C19H17BrN6
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1
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| 1 |
IC50 = 300 nM
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CP0425261
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N-(1-benzofuran-5-yl)-N,2,6-trimethylfuro[2,3-d]pyrimidin-4-amine
Show/Hide
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C17H15N3O2
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1
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| 1 |
IC50 = 306.6 nM
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CP0707858
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3-Hydroxy-4-[4-(2-nitro-vinyl)-phenoxysulfonyl]-benzoic acid
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C15H11NO8S
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1
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| 1 |
IC50 = 310 nM
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CP0530110
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(3-Chloro-4-fluoro-phenyl)-[6-(2-isopropylamino-ethoxy)-7-methoxy-quinazolin-4-yl]-amine
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C20H22ClFN4O2
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1
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| 1 |
IC50 = 310 nM
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CP0123794
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3-{5-[(3-bromophenyl)amino]-1H-pyrazolo[4,3-g]quinazolin-1-yl}propane-1,2-diol
Show/Hide
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C18H16BrN5O2
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1
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| 1 |
IC50 = 318 nM
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CP0441546
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4-(Benzylamino)quinazoline deriv. 7
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C15H13N3
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1
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| 1 |
IC50 = 320 nM
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CP0322881
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4-Anilinopyrido[3,4-d]pyrimidine 36
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C15H11BrN4OS
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1
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| 1 |
IC50 = 340 nM
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CP0307724
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N-(3-ethynylphenyl)-6,7-bis(2-methoxyethoxy)quinolin-4-amine
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C23H24N2O4
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1
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| 1 |
IC50 = 340 nM
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CP0399064
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N-butyl-N-(4-methoxyphenyl)-2,6-dimethylfuro[2,3-d]pyrimidin-4-amine
Show/Hide
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C19H23N3O2
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1
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| 1 |
IC50 = 340.1 nM
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CP0050726
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4-Anilino quinazoline deriv. 10
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C14H11N3
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2
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| 1 |
IC50 = 344 nM
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| 2 |
IC50 = 346 nM
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CP0544970
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N-[2-[2-(dimethylamino)ethyl-methylamino]-4-methoxy-5-[[6-(1-methylindol-3-yl)pyrazin-2-yl]amino]phenyl]prop-2-enamide
Show/Hide
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C28H33N7O2
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1
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| 1 |
IC50 = 348 nM
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CP0294102
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N-[3-[5-[2-[4-(4-ethylpiperazin-1-yl)anilino]pyrimidin-4-yl]imidazo[2,1-b][1,3]thiazol-6-yl]phenyl]-2-phenylacetamide
Show/Hide
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C35H34N8OS
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1
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| 1 |
IC50 = 350 nM
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CP0540103
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4-Anilinoquinazoline deriv. 41
Show/Hide
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C14H9BrN4O2
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1
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| 1 |
IC50 = 355 nM
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CP0177493
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6-methoxy-7-(1-methylpiperidin-4-yloxy)-4-((1R,2S)-2-phenylcyclopropylamino)quinoline-3-carbonitrile
Show/Hide
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C26H28N4O2
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1
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| 1 |
IC50 = 360 nM
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CP0276502
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N-[4-(3-chloro-4-fluoroanilino)-7-(2-methoxyethoxy)pyrido[3,2-d]pyrimidin-6-yl]prop-2-enamide
Show/Hide
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C19H17ClFN5O3
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1
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| 1 |
IC50 = 377 nM
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CP0203178
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N-[3-[2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]-5-methyl-7-oxopyrido[2,3-d]pyrimidin-8-yl]phenyl]prop-2-enamide
Show/Hide
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C29H31N7O3
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1
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| 1 |
IC50 = 386 nM
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CP0409032
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7-Methoxy-4-(2-phenyl-cyclopropylamino)-quinazolin-6-ol
Show/Hide
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C18H17N3O2
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1
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| 1 |
IC50 = 390 nM
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CP0707857
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4-Methylcarbamoyl-benzenesulfonic acid 4-(2-nitro-vinyl)-phenyl ester
Show/Hide
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C16H14N2O6S
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1
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| 1 |
IC50 = 400 nM
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CP0285574
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(3-Bromo-phenyl)-(6,7,8,9-tetrahydro-5H-pyrimido[4,5-b]indol-4-yl)-amine
Show/Hide
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C16H15BrN4
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1
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| 1 |
IC50 = 400 nM
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CP0195737
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7-methoxy-6-(2-morpholinoethoxy)-4-((1R,2S)-2-phenylcyclopropylamino)quinoline-3-carbonitrile
Show/Hide
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C26H28N4O3
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1
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| 1 |
IC50 = 405 nM
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CP0140479
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N-[4-[3-bromo-4-[(dimethylamino)methyl]anilino]quinazolin-6-yl]prop-2-enamide
Show/Hide
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C20H20BrN5O
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1
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| 1 |
IC50 = 416 nM
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CP0801534
|
ERLOTINIB HYDROCHLORIDE
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C22H24ClN3O4
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1
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| 1 |
IC50 = 420 nM
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CP0464797
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1-(3-chloro-4-fluorophenyl)-2-(6,7-dimethoxyquinazolin-4-yl)hydrazine
Show/Hide
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C16H14ClFN4O2
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1
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| 1 |
IC50 = 430 nM
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CP0036405
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N-[4-(3-chloro-4-fluoroanilino)-7-(3-morpholin-4-ylpropoxy)pyrido[3,2-d]pyrimidin-6-yl]prop-2-enamide
Show/Hide
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C23H24ClFN6O3
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1
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| 1 |
IC50 = 434 nM
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CP0319919
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[(2R)-1-methoxy-3-(2-nitroimidazol-1-yl)propan-2-yl] 4-[(2-hydroxy-5-oxocyclopenta-1,3-dien-1-yl)methylideneamino]benzoate
Show/Hide
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C20H18N4O7
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1
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| 1 |
IC50 = 434.782609 nM
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CP0469577
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4-Anilinoquinazoline deriv. 42
Show/Hide
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C14H11BrN4
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1
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| 1 |
IC50 = 439 nM
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CP0362891
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3-({4-[(3-bromophenyl)amino]pyrido[3,4-d]pyrimidin-6-yl}amino)propanoic acid
Show/Hide
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C16H14BrN5O2
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1
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| 1 |
IC50 = 449 nM
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CP0418995
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2-Amino-4-[(3-bromophenyl)amino]-6,7-dimethoxyquinazoline Trihydrochloride
Show/Hide
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C16H15BrN4O2
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1
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| 1 |
IC50 = 463 nM
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CP0077468
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4-N-(3-bromophenyl)-9H-pyrimido[4,5-b]indole-2,4-diamine
Show/Hide
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C16H12BrN5
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1
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| 1 |
IC50 = 493 nM
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CP0153229
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[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl 4-[2-methoxy-4-[(E)-2-nitroethenyl]phenoxy]sulfonylbenzoate
Show/Hide
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C26H24N6O11S
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1
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| 1 |
IC50 = 500 nM
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CP0009783
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3-(4-Hydroxyphenyl)-4-((3-chlorophenyl)amino)pyrazolo[3,4-d]pyrimidine
Show/Hide
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C17H12ClN5O
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1
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| 1 |
IC50 = 500 nM
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CP0012538
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3-((4-Aminophenyl)amino)-4-((3-chlorophenyl)amino)-1H-pyrazolo[3,4-d]pyrimidine
Show/Hide
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C17H14ClN7
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1
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| 1 |
IC50 = 500 nM
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CP0208223
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5-{[(5Z)-4-[(4-chloro-2-fluorophenyl)amino]-6-oxo-5H,6H,7H-pyrrolo[2,3-d]pyrimidin-5-ylidene]methyl}-N-[2-(diethylamino)ethyl]-4-methyl-1H-pyrrole-2-carboxamide
Show/Hide
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C25H27ClFN7O2
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1
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| 1 |
IC50 = 500 nM
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CP0051266
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4-[(3-chloro-4-fluorophenyl)amino]-8-fluoro-6-[(1H-imidazol-4-ylmethyl)amino]quinoline-3-carbonitrile
Show/Hide
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C20H13ClF2N6
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1
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| 1 |
IC50 = 500 nM
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CP0400609
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2-Amino-4-(N-methyl-m-bromoanilino)-6-(2,5-dimethoxybenzyl)-7-methyl-pyrrolo[2,3-d]pyrimidine
Show/Hide
|
C23H24BrN5O2
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1
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| 1 |
IC50 = 500 nM
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CP0374755
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N-[3-[2-[4-[2-(dimethylamino)ethyl-methylamino]-2-methoxyanilino]-5-methyl-7-oxopyrido[2,3-d]pyrimidin-8-yl]phenyl]prop-2-enamide
Show/Hide
|
C29H33N7O3
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1
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| 1 |
IC50 = 521 nM
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CP0276149
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N-(3-iodophenyl)-7-nitroquinazolin-4-amine
Show/Hide
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C14H9IN4O2
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1
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| 1 |
IC50 = 540 nM
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CP0564476
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BLU-945
Show/Hide
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C28H37FN6O3S
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1
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| 1 |
IC50 = 544 nM
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CP0350000
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4-N-(3-bromophenyl)-7-N-methylpyrido[2,3-d]pyrimidine-4,7-diamine
Show/Hide
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C14H12BrN5
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1
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| 1 |
IC50 = 552 nM
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CP0345034
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[(2R)-1-(4-tert-butylphenoxy)-3-(2-nitroimidazol-1-yl)propan-2-yl] 4-[(2-hydroxy-5-oxocyclopenta-1,3-dien-1-yl)methylideneamino]benzoate
Show/Hide
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C29H28N4O7
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1
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| 1 |
IC50 = 555.555556 nM
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CP0202618
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4-N-[3-(trifluoromethyl)phenyl]quinazoline-4,6-diamine
Show/Hide
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C15H11F3N4
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1
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| 1 |
IC50 = 574 nM
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CP0288954
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4-Anilino quinazoline deriv. 17
Show/Hide
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C15H10F3N3
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1
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| 1 |
IC50 = 577 nM
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CP0543558
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2-[4-(difluoromethyl)-6-[2-[4-[[4-(hydroxymethyl)piperidin-1-yl]methyl]phenyl]ethynyl]-7-methylindazol-2-yl]-2-spiro[6,7-dihydropyrrolo[1,2-c]imidazole-5,1'-cyclopropane]-1-yl-N-(1,3-thiazol-2-yl)acetamide
Show/Hide
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C37H37F2N7O2S
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1
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| 1 |
IC50 = 577 nM
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CP0497324
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4-N-benzylpyrido[4,3-d]pyrimidine-4,7-diamine
Show/Hide
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C14H13N5
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2
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| 1 |
IC50 = 580 nM
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| 2 |
IC50 = 2085 nM
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CP0137246
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2-[({4-[(3-bromophenyl)amino]-8H-pyrrolo[3,2-g]quinazolin-6-yl}methyl)(methyl)amino]acetic acid
Show/Hide
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C20H18BrN5O2
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1
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| 1 |
IC50 = 584 nM
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CP0496699
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4-(Benzylamino)quinazoline deriv. 38
Show/Hide
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C16H15N3O2
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1
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| 1 |
IC50 = 588 nM
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CP0285521
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[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl 4-[4-[(E)-2-nitroethenyl]phenoxy]sulfonylbenzoate
Show/Hide
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C25H22N6O10S
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1
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| 1 |
IC50 = 600 nM
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CP0497325
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4-[(Phenylmethyl)amino]-pyrido[3,2-d]pyrimidine
Show/Hide
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C14H12N4
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1
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| 1 |
IC50 = 603 nM
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CP0060760
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US9447106, 27b (peak 2)
Show/Hide
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C27H29N5O3
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1
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| 1 |
IC50 = 606 nM
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CP0093135
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N-[3-[5-[2-(3-morpholin-4-ylanilino)pyrimidin-4-yl]imidazo[2,1-b][1,3]thiazol-6-yl]phenyl]-2-phenylacetamide
Show/Hide
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C33H29N7O2S
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1
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| 1 |
IC50 = 610 nM
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CP0327963
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N-(3-bromophenyl)-9H-pyrimido[4,5-b]indol-4-amine
Show/Hide
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C16H11BrN4
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1
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| 1 |
IC50 = 630 nM
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CP0511889
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(6,7-Dimethoxy-quinazolin-4-yl)-isoquinolin-3-yl-amine
Show/Hide
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C19H16N4O2
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1
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| 1 |
IC50 = 660 nM
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CP0487353
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4-N-(4-methoxyphenyl)pyrido[4,3-d]pyrimidine-4,7-diamine
Show/Hide
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C14H13N5O
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1
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| 1 |
IC50 = 670 nM
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CP0081939
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4-[(3-Bromophenyl)amino]-7-fluoropyrido[2,3-d]pyrimidine
Show/Hide
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C13H8BrFN4
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1
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| 1 |
IC50 = 684 nM
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CP0034833
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4-[(3-bromophenyl)-amino]pyrido[2,3-d]pyrimidine
Show/Hide
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C13H9BrN4
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1
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| 1 |
IC50 = 688 nM
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CP0546833
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(3S,4R)-3-ethyl-3-fluoro-1-[4-[[8-[(2R,3S)-2-methyl-3-(methylsulfonylmethyl)azetidin-1-yl]-5-propan-2-ylisoquinolin-3-yl]amino]pyrimidin-2-yl]piperidin-4-ol
Show/Hide
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C29H39FN6O3S
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1
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| 1 |
IC50 = 709 nM
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CP0059062
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N-[3-[5-chloro-2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]oxyphenyl]prop-2-enamide
Show/Hide
|
C25H27ClN6O3
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1
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| 1 |
IC50 = 710 nM
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CP0454297
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(3-Chloro-4-fluoro-phenyl)-(6,7-dimethoxy-quinazolin-4-yl)-diazene
Show/Hide
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C16H12ClFN4O2
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1
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| 1 |
IC50 = 730 nM
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CP0391256
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4-(3-bromophenoxy)quinazoline
Show/Hide
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C14H9BrN2O
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1
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| 1 |
IC50 = 756 nM
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CP0226526
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N-(3-bromophenyl)-9-methyl-9H-pyrimido[4,5-b]indol-4-amine
Show/Hide
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C17H13BrN4
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1
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| 1 |
IC50 = 769 nM
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CP0288783
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4-N-phenylquinazoline-4,6-diamine
Show/Hide
|
C14H12N4
|
1
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| 1 |
IC50 = 770 nM
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CP0449617
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(6,7-Dimethoxy-quinazolin-4-yl)-quinoxalin-2-yl-amine
Show/Hide
|
C18H15N5O2
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1
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| 1 |
IC50 = 780 nM
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CP0568877
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(3S,4R)-3-fluoro-3-methyl-1-[4-[[8-[(2R,3S)-2-methyl-3-(methylsulfonylmethyl)azetidin-1-yl]-5-propan-2-yl-2,7-naphthyridin-3-yl]amino]pyrimidin-2-yl]piperidin-4-ol
Show/Hide
|
C27H36FN7O3S
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1
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| 1 |
IC50 = 781 nM
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CP0009912
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3-(4-Aminophenyl)-4-((3-chlorophenyl)amino)-1H-pyrazolo[3,4-d]pyrimidine Hydrochloride
Show/Hide
|
C17H13ClN6
|
1
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| 1 |
IC50 = 800 nM
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CP0010589
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3-((3-Methoxyphenyl)amino)-4-((3-chlorophenyl)amino)-1H-pyrazolo[3,4-d]pyrimidine
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C18H15ClN6O
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1
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| 1 |
IC50 = 800 nM
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CP0011470
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3-(3-Aminophenyl)-4-((3-chlorophenyl)amino)-1H-pyrazolo[3,4-d]pyrimidine
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C17H13ClN6
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1
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| 1 |
IC50 = 800 nM
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CP0322683
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butyl N-[4-[(6,7-dimethoxyquinazolin-4-yl)amino]phenyl]carbamate
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C21H24N4O4
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1
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| 1 |
IC50 = 800 nM
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CP0263946
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N-(3-chlorophenyl)-7-nitroquinazolin-4-amine
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C14H9ClN4O2
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1
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| 1 |
IC50 = 810 nM
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CP0375915
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Benzo[1,2,4]triazin-3-yl-(6,7-dimethoxy-quinazolin-4-yl)-amine
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C17H14N6O2
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1
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| 1 |
IC50 = 820 nM
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CP0507449
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4-(2,3-Dihydro-indol-1-yl)-6,7-dimethoxy-quinazoline
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C18H17N3O2
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1
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| 1 |
IC50 = 820 nM
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CP0540615
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4-N-(3-fluorophenyl)pyrido[4,3-d]pyrimidine-4,7-diamine
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C13H10FN5
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1
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| 1 |
IC50 = 840 nM
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CP0424485
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4-Anilino quinazoline deriv. 12
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C15H13N3O
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1
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| 1 |
IC50 = 842 nM
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CP0486641
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N-[5-[4-[3-chloro-4-(pyridin-2-ylmethoxy)anilino]-7H-pyrrolo[2,3-d]pyrimidin-5-yl]-2-[2-(dimethylamino)ethoxy]phenyl]prop-2-enamide
Show/Hide
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C31H30ClN7O3
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1
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| 1 |
IC50 = 862 nM
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CP0284439
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4-(3-chloro-4-(pyridin-2-ylmethoxy)phenylamino)-3-methyl-N-(2-morpholinoethyl)-1H-pyrrolo[3,2-d]pyridazine-2-carboxamide
Show/Hide
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C26H28ClN7O3
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1
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| 1 |
IC50 = 867 nM
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CP0288784
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4-Anilinoquinazoline deriv. 44
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C14H9BrN4O2
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2
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| 1 |
IC50 = 897 nM
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| 2 |
IC50 = 900 nM
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CP0073706
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propyl N-[4-[(6,7-dimethoxyquinazolin-4-yl)amino]-2-methylphenyl]carbamate
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C21H24N4O4
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1
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| 1 |
IC50 = 900 nM
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CP0137822
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ethyl N-[4-[(6,7-dimethoxyquinazolin-4-yl)amino]-2-methylphenyl]carbamate
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C20H22N4O4
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1
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| 1 |
IC50 = 900 nM
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CP0322684
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ethyl N-[2-chloro-5-[(6,7-dimethoxyquinazolin-4-yl)amino]phenyl]carbamate
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C19H19ClN4O4
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1
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| 1 |
IC50 = 900 nM
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CP0416813
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N-(3-ethynylphenyl)-2-hydroxy-5-[7-(hydroxyamino)-7-oxoheptoxy]benzamide
Show/Hide
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C22H24N2O5
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1
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| 1 |
IC50 = 900 nM
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CP0202620
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4-Anilino quinazoline deriv. 13
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C15H13N3
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1
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| 1 |
IC50 = 910 nM
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CP0429014
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(6,7-Dimethoxy-quinazolin-4-yl)-indan-1-yl-amine
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C19H19N3O2
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1
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| 1 |
IC50 = 910 nM
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CP0050731
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4-N-(3-bromophenyl)pyrido[2,3-d]pyrimidine-4,7-diamine
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C13H10BrN5
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1
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| 1 |
IC50 = 940 nM
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CP0503995
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1-{4-[(3-chlorophenyl)amino-6-quinazolinyl}-3-{2-[N-(2-chloropropyl)-N-4-methoxyphenylethylenamine]} triazene
Show/Hide
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C26H27Cl2N7O
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1
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| 1 |
IC50 = 970 nM
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CP0383214
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4-Anilinoquinazoline deriv. 52
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C15H12BrN3O
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2
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| 1 |
IC50 = 974 nM
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| 2 |
IC50 > 10000 nM
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CP0290287
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4-(3-chloro-4-(3-fluorobenzyloxy)phenylamino)-3-methyl-N-(3-(4-methylpiperazin-1-yl)propyl)-1H-pyrrolo[3,2-d]pyridazine-2-carboxamide
Show/Hide
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C29H33ClFN7O2
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1
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| 1 |
IC50 = 980 nM
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CP0701326
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4-[4-(2-Nitro-vinyl)-phenoxysulfonyl]-benzoic acid
Show/Hide
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C15H11NO7S
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1
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| 1 |
IC50 = 1000 nM
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CP0506529
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4-Anilinoquinazoline deriv. 47
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C14H9BrN4O2
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1
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| 1 |
IC50 = 1000 nM
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CP0507693
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4-N-[(3-bromophenyl)methyl]pyrido[4,3-d]pyrimidine-4,7-diamine
Show/Hide
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C14H12BrN5
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1
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| 1 |
IC50 = 1000 nM
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CP0002454
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3-((3-Chlorophenyl)amino)-4-(phenylamino)-1H-pyrazolo[3,4-d]pyrimidine
Show/Hide
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C17H13ClN6
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1
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| 1 |
IC50 = 1000 nM
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CP0290732
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2-phenyl-N-(3-(5-(2-(1,2,3,4-tetrahydroisoquinolin-6-ylamino)pyrimidin-4-yl)imidazo[2,1-b]thiazol-6-yl)phenyl)acetamide
Show/Hide
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C32H27N7OS
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1
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| 1 |
IC50 = 1000 nM
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CP0151097
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propyl N-[2-chloro-4-[(6,7-dimethoxyquinazolin-4-yl)amino]phenyl]carbamate
Show/Hide
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C20H21ClN4O4
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1
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| 1 |
IC50 = 1000 nM
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CP0549254
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ethyl N-[2-chloro-4-[(6,7-dimethoxyquinazolin-4-yl)amino]phenyl]carbamate
Show/Hide
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C19H19ClN4O4
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1
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| 1 |
IC50 = 1000 nM
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CP0520799
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N-[3-[[2-[4-[4-(diethylamino)piperidin-1-yl]-2-methoxyanilino]pyrimidin-4-yl]carbamoylamino]phenyl]prop-2-enamide
Show/Hide
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C30H38N8O3
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1
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| 1 |
IC50 = 1013 nM
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CP0204540
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US10434101, Compound I-10
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C27H27F3N6O4
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1
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| 1 |
IC50 = 1034 nM
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CP0798078
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4-Oxo-pent-2-enoic acid [4-(3-bromo-phenylamino)-quinazolin-6-yl]-amide
Show/Hide
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C19H15BrN4O2
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1
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| 1 |
IC50 = 1039 nM
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CP0055009
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N-[3-[2-[4-[2-(dimethylamino)ethoxy]-2-methoxyanilino]-5-methyl-7-oxopyrido[2,3-d]pyrimidin-8-yl]phenyl]prop-2-enamide
Show/Hide
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C28H30N6O4
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1
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| 1 |
IC50 = 1054 nM
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CP0416811
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N-[3-[[3-chloro-4-[(3-fluorophenyl)methoxy]phenyl]carbamoyl]-4-hydroxyphenyl]-N'-hydroxyheptanediamide
Show/Hide
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C27H27ClFN3O6
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1
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| 1 |
IC50 = 1100 nM
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CP0489771
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N-[5-[(3-ethynylphenyl)carbamoyl]-4-hydroxy-2-methoxyphenyl]-N'-hydroxyheptanediamide
Show/Hide
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C23H25N3O6
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1
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| 1 |
IC50 = 1120 nM
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CP0150154
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4-(3-chloro-4-(3-fluorobenzyloxy)phenylamino)-N-(2-(diethylamino)ethyl)-3-methyl-1H-pyrrolo[3,2-d]pyridazine-2-carboxamide
Show/Hide
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C27H30ClFN6O2
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1
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| 1 |
IC50 = 1160 nM
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CP0339915
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2-{5-[(3-bromophenyl)amino]-1H-pyrazolo[4,3-g]quinazolin-1-yl}acetic acid
Show/Hide
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C17H12BrN5O2
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1
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| 1 |
IC50 = 1196 nM
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CP0462131
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2-Amino-4-(N-methyl-m-bromoanilino)-6-(2-methylbenzyl)-7-methyl-pyrrolo[2,3-d]pyrimidine
Show/Hide
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C22H22BrN5
|
1
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| 1 |
IC50 = 1200 nM
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CP0545094
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(3S,4R)-3-fluoro-4-methyl-1-[4-[[8-[(2R,3S)-2-methyl-3-(methylsulfonylmethyl)azetidin-1-yl]-5-propan-2-ylisoquinolin-3-yl]amino]pyrimidin-2-yl]piperidin-4-ol
Show/Hide
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C28H37FN6O3S
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1
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| 1 |
IC50 = 1206 nM
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CP0150683
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ethyl 4-[3-chloro-4-[(3-fluorophenyl)methoxy]anilino]-7-methyl-6H-pyrrolo[3,4-d]pyridazine-5-carboxylate
Show/Hide
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C23H20ClFN4O3
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1
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| 1 |
IC50 = 1210 nM
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CP0429052
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4-N-(2-nitrophenyl)pyrido[4,3-d]pyrimidine-4,7-diamine
Show/Hide
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C13H10N6O2
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1
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| 1 |
IC50 = 1250 nM
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CP0510895
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4-tert-Butylcarbamoyl-benzenesulfonic acid 4-(2-nitro-vinyl)-phenyl ester
Show/Hide
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C19H20N2O6S
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1
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| 1 |
IC50 = 1300 nM
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CP0571685
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(3S,4R)-3-fluoro-3-methyl-1-[4-[[8-[3-(methylsulfonylmethyl)azetidin-1-yl]-5-propan-2-ylisoquinolin-3-yl]amino]pyrimidin-2-yl]piperidin-4-ol
Show/Hide
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C27H35FN6O3S
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1
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| 1 |
IC50 = 1362 nM
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CP0399604
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N-(3-bromophenyl)-5,6-dimethoxyquinazolin-4-amine
Show/Hide
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C16H14BrN3O2
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2
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| 1 |
IC50 = 1367 nM
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| 2 |
IC50 = 1370 nM
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CP0675391
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4-(2-tert-Butoxycarbonylamino-ethylcarbamoyl)-benzenesulfonic acid 4-(2-nitro-vinyl)-phenyl ester
Show/Hide
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C22H25N3O8S
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1
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| 1 |
IC50 = 1400 nM
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CP0358875
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4-(Benzylamino)quinazoline deriv. 30
Show/Hide
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C15H14N4
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1
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| 1 |
IC50 = 1400 nM
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CP0053637
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(S)-N-(4-(3-chloro-4-fluorophenylamino)-7-(tetrahydrofuran-3-yloxy)quinazolin-6-yl)-4-(dimethylamino)but-2-enamide
Show/Hide
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C24H25ClFN5O3
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1
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| 1 |
IC50 = 1401 nM
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CP0377643
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N-[3-[[4-chloro-3-(trifluoromethyl)phenyl]carbamoyl]-4-hydroxyphenyl]-N'-hydroxyheptanediamide
Show/Hide
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C21H21ClF3N3O5
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1
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| 1 |
IC50 = 1410 nM
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CP0489767
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N-[3-[(3-fluorophenyl)carbamoyl]-4-hydroxyphenyl]-N'-hydroxyheptanediamide
Show/Hide
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C20H22FN3O5
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1
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| 1 |
IC50 = 1410 nM
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CP0384026
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4-[(Phenylmethyl)amino]-pyrido[4,3-d]pyrimidine
Show/Hide
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C14H12N4
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1
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| 1 |
IC50 = 1460 nM
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CP0363514
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4-[4-(2-Nitro-vinyl)-phenoxysulfonyl]-benzoic acid methyl ester
Show/Hide
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C16H13NO7S
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1
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| 1 |
IC50 = 1500 nM
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CP0468056
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2,2 -Dithiobis(7-methyl-1H-indole-3-propanoic acid)
Show/Hide
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C24H24N2O4S2
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1
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| 1 |
IC50 = 1500 nM
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CP0112137
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(3-Bromo-phenyl)-(5,6-dimethyl-7H-pyrrolo[2,3-d]pyrimidin-4-yl)-amine
Show/Hide
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C14H13BrN4
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1
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| 1 |
IC50 = 1500 nM
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CP0005594
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3-(4-(BOC-amino)phenyl)-4-((3-chlorophenyl)amino)-1H-pyrazolo[3,4-d]pyrimidine
Show/Hide
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C22H21ClN6O2
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1
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| 1 |
IC50 = 1500 nM
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CP0006770
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3-(4-Methoxyphenyl)-4-((3-chlorophenyl)amino)-1H-pyrazolo[3,4-d]pyrimidine
Show/Hide
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C18H14ClN5O
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1
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| 1 |
IC50 = 1500 nM
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CP0007624
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3-((3-Chlorobenzyl)amino)-4-((3-chlorophenyl)amino)-1H-pyrazolo[3,4-d]pyrimidine
Show/Hide
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C18H14Cl2N6
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1
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| 1 |
IC50 = 1500 nM
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CP0008701
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3-((4-(Dimethylamino)phenyl)amino)-4-((3-chlorophenyl)amino)-1H-pyrazolo[3,4-d]pyrimidine
Show/Hide
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C19H18ClN7
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1
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| 1 |
IC50 = 1500 nM
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CP0008833
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3-{4-[(3-chlorophenyl)amino]-1H-pyrazolo[3,4-d]pyrimidin-3-yl}phenol
Show/Hide
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C17H12ClN5O
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1
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| 1 |
IC50 = 1500 nM
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CP0009842
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3-((4-Methoxyphenyl)-amino)-4-((3-chlorophenyl)amino)-1H-pyrazolo[3,4-d]pyrimidine
Show/Hide
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C18H15ClN6O
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1
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| 1 |
IC50 = 1500 nM
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CP0014366
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3-((3-Chlorophenyl)amino)-4-(benzylamino)-1H-pyrazolo[3,4-d]pyrimidine
Show/Hide
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C18H15ClN6
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1
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| 1 |
IC50 = 1500 nM
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CP0561775
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N-[3-[[2-[4-[4-(dimethylamino)piperidin-1-yl]-2-methoxyanilino]pyrimidin-4-yl]carbamoylamino]phenyl]prop-2-enamide
Show/Hide
|
C28H34N8O3
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1
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| 1 |
IC50 = 1535 nM
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CP0523892
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4-N-(3-aminophenyl)pyrido[4,3-d]pyrimidine-4,7-diamine
Show/Hide
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C13H12N6
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1
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| 1 |
IC50 = 1550 nM
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CP0416812
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N-[5-[(3-chloro-4-fluorophenyl)carbamoyl]-4-hydroxy-2-methoxyphenyl]-N'-hydroxyheptanediamide
Show/Hide
|
C21H23ClFN3O6
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1
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| 1 |
IC50 = 1560 nM
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CP0513510
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N-[3-[4-[4-[(1,3-dioxoisoindol-2-yl)methyl]anilino]-7H-pyrrolo[2,3-d]pyrimidin-5-yl]phenyl]prop-2-enamide
Show/Hide
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C30H22N6O3
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1
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| 1 |
IC50 = 1570 nM
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CP0571686
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(3S,4R)-3-fluoro-3-methyl-1-[4-[[8-[3-(methylsulfonylmethyl)azetidin-1-yl]-5-propan-2-yl-2,7-naphthyridin-3-yl]amino]pyrimidin-2-yl]piperidin-4-ol
Show/Hide
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C26H34FN7O3S
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1
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| 1 |
IC50 = 1608 nM
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CP0177494
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6-(benzyloxy)-7-methoxy-4-((1R,2S)-2-phenylcyclopropylamino)quinoline-3-carbonitrile
Show/Hide
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C27H23N3O2
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1
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| 1 |
IC50 = 1610 nM
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CP0528893
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2,3-Dihydro-2-thioxo-1H-indole-3-propanoic Acid
Show/Hide
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C11H11NO2S
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1
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| 1 |
IC50 = 1620 nM
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CP0375864
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4-N-[(2-bromophenyl)methyl]pyrido[4,3-d]pyrimidine-4,7-diamine
Show/Hide
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C14H12BrN5
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1
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| 1 |
IC50 = 1670 nM
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CP0091116
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2-benzyl-N4-(3-bromophenyl)-1H-indole-4,6-diamine
Show/Hide
|
C19H16BrN5
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1
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| 1 |
IC50 = 1670 nM
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CP0491530
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N-[3-[4-[3-chloro-4-(pyridin-2-ylmethoxy)anilino]-7H-pyrrolo[2,3-d]pyrimidin-5-yl]phenyl]prop-2-enamide
Show/Hide
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C27H21ClN6O2
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1
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| 1 |
IC50 = 1675 nM
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CP0402939
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N-[3-chloro-4-[(3-fluorophenyl)methoxy]phenyl]-6,7-dimethoxyquinolin-4-amine
Show/Hide
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C24H20ClFN2O3
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1
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| 1 |
IC50 = 1700 nM
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CP0478429
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N-[3-[[2-[4-[2-(dimethylamino)ethyl-methylamino]-2-methoxyanilino]pyrimidin-4-yl]carbamoylamino]phenyl]prop-2-enamide
Show/Hide
|
C26H32N8O3
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1
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| 1 |
IC50 = 1703 nM
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CP0385341
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2-{4-[(3-bromophenyl)amino]-8H-pyrrolo[3,2-g]quinazolin-8-yl}acetic acid
Show/Hide
|
C18H13BrN4O2
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1
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| 1 |
IC50 = 1780 nM
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CP0546825
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(3S,4R)-3-fluoro-3-methyl-1-[4-[[8-[(2R,3S)-2-methyl-3-(methylsulfonylmethyl)azetidin-1-yl]-5-propan-2-ylisoquinolin-3-yl]amino]pyrimidin-2-yl]piperidin-4-ol
Show/Hide
|
C28H37FN6O3S
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1
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| 1 |
IC50 = 1780 nM
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CP0372362
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4-N-[3-(dimethylamino)phenyl]pyrido[4,3-d]pyrimidine-4,7-diamine
Show/Hide
|
C15H16N6
|
1
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| 1 |
IC50 = 1790 nM
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CP0771877
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2-Hydroxy-4-[4-(2-nitro-vinyl)-phenoxysulfonyl]-benzoic acid methyl ester
Show/Hide
|
C16H13NO8S
|
1
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| 1 |
IC50 = 1800 nM
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CP0091578
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8-chloro-4-[(3-chloro-4-fluorophenyl)amino]-6-[(1H-imidazol-4-ylmethyl)amino]quinoline-3-carbonitrile
Show/Hide
|
C20H13Cl2FN6
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1
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| 1 |
IC50 = 1800 nM
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CP0489769
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N-[3-[(3,4-dichlorophenyl)carbamoyl]-4-hydroxyphenyl]-N'-hydroxyheptanediamide
Show/Hide
|
C20H21Cl2N3O5
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1
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| 1 |
IC50 = 1800 nM
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CP0495059
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4-N-{[3-(trifluoromethyl)phenyl]methyl}pyrido[4,3-d]pyrimidine-4,7-diamine
Show/Hide
|
C15H12F3N5
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1
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| 1 |
IC50 = 1950 nM
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CP0042713
|
N-[(E)-2-(2,5-dihydroxyphenyl)ethenyl]formamide
Show/Hide
|
C9H9NO3
|
1
|
| 1 |
IC50 = 2000 nM
|
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CP0493032
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4-N-(3-bromophenyl)-7-N,7-N-dimethyl-6-nitroquinazoline-4,7-diamine
Show/Hide
|
C16H14BrN5O2
|
1
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| 1 |
IC50 = 2000 nM
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CP0453645
|
4-[(Phenylmethyl)amino]-pyrido[3,4-d]pyrimidine
Show/Hide
|
C14H12N4
|
1
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| 1 |
IC50 = 2030 nM
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CP0277539
|
4-[(3-chloro-4-fluorophenyl)amino]-6-[(1H-imidazol-4-ylmethyl)amino]-8-methoxyquinoline-3-carbonitrile
Show/Hide
|
C21H16ClFN6O
|
1
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| 1 |
IC50 = 2080 nM
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CP0177495
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6-(4-(aminomethyl)phenyl)-4-((1R,2S)-2-phenylcyclopropylamino)quinoline-3-carbonitrile
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C26H22N4
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1
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| 1 |
IC50 = 2100 nM
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CP0002017
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5,6-Bis-(4-fluoro-phenylamino)-isoindole-1,3-dione
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C20H13F2N3O2
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1
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| 1 |
IC50 = 2200 nM
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CP0542855
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1-{4-[(3-chlorophenyl)amino-6-quinazolinyl}-3-{2-[N-(2-chloroethyl)-N-4-chlorophenylethylenamine]} triazene
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C24H22Cl3N7
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1
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| 1 |
IC50 = 2200 nM
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CP0192549
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2,4-diaminofuro[2,3-d]pyrimidine, 8
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C18H22N4O2
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1
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| 1 |
IC50 = 2200 nM
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CP0550670
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N-methyl-6-(trifluoromethyl)-N-(3,4,5-trimethoxyphenyl)quinolin-4-amine
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C20H19F3N2O3
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1
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| 1 |
IC50 = 2200 nM
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CP0521635
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N-[3-[[5-chloro-2-[2-methoxy-4-(4-morpholin-4-ylpiperidin-1-yl)anilino]pyrimidin-4-yl]carbamoylamino]phenyl]prop-2-enamide
Show/Hide
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C30H35ClN8O4
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1
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| 1 |
IC50 = 2210 nM
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CP0482153
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N-[3-[(3,4-difluorophenyl)carbamoyl]-4-hydroxyphenyl]-N'-hydroxyheptanediamide
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C20H21F2N3O5
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1
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| 1 |
IC50 = 2220 nM
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CP0500354
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N-[5-[4-[(1-benzylindazol-5-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-5-yl]-2-(2-hydroxyethoxy)phenyl]prop-2-enamide
Show/Hide
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C31H27N7O3
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1
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| 1 |
IC50 = 2236 nM
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CP0489770
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N-[3-[(3-ethynylphenyl)carbamoyl]-4-hydroxyphenyl]-N'-hydroxyoctanediamide
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C23H25N3O5
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1
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| 1 |
IC50 = 2250 nM
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CP0287177
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4-Anilinopyrido[3,4-d]pyrimidine 21
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C20H21BrN6O
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1
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| 1 |
IC50 = 2282 nM
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CP0081937
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4-N-(3-bromophenyl)-7-N,7-N-dimethylpyrido[2,3-d]pyrimidine-4,7-diamine
Show/Hide
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C15H14BrN5
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1
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| 1 |
IC50 = 2300 nM
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CP0526436
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N-[3-[[2-[2-methoxy-4-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]anilino]pyrimidin-4-yl]carbamoylamino]phenyl]prop-2-enamide
Show/Hide
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C31H39N9O3
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1
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| 1 |
IC50 = 2338 nM
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CP0416674
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N'-hydroxy-N-[4-hydroxy-3-(phenylcarbamoyl)phenyl]heptanediamide
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C20H23N3O5
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1
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| 1 |
IC50 = 2340 nM
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CP0402833
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6,7-bis(2-methoxyethoxy)-N-(3,4,5-trimethoxyphenyl)quinazolin-4-amine
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C23H29N3O7
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1
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| 1 |
IC50 = 2400 nM
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CP0525974
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4-N-[(4-bromophenyl)methyl]pyrido[4,3-d]pyrimidine-4,7-diamine
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C14H12BrN5
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1
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| 1 |
IC50 = 2460 nM
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CP0921325
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4-[2-Methoxy-4-(2-nitro-propenyl)-phenoxysulfonyl]-benzoic acid
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C17H15NO8S
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1
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| 1 |
IC50 = 2500 nM
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CP0438549
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4-(3-Bromo-phenoxy)-6,7-dimethoxy-quinoline
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C17H14BrNO3
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1
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| 1 |
IC50 = 2500 nM
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CP0400032
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4-N-(4-chloro-2-fluorophenyl)-6-[(2,4-dichlorophenyl)methyl]-7H-pyrrolo[2,3-d]pyrimidine-2,4-diamine
Show/Hide
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C19H13Cl3FN5
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1
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| 1 |
IC50 = 2500 nM
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CP0221562
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6-(4-(morpholinomethyl)phenyl)-4-((1R,2S)-2-phenylcyclopropylamino)quinoline-3-carbonitrile
Show/Hide
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C30H28N4O
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1
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| 1 |
IC50 = 2530 nM
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CP0050992
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7-methoxy-4-((1R,2S)-2-phenylcyclopropylamino)quinoline-3-carbonitrile
Show/Hide
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C20H17N3O
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1
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| 1 |
IC50 = 2580 nM
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CP0399994
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4-Anilidoquinazoline deriv. 12a
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C14H9Cl2N3
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1
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| 1 |
IC50 = 2700 nM
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CP0707856
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4-[2-Methoxy-4-(2-nitro-vinyl)-phenoxysulfonyl]-benzoic acid
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C16H13NO8S
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1
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| 1 |
IC50 = 2800 nM
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CP0020298
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(3,4-Dimethoxy-phenyl)-(6,7-dimethoxy-quinazolin-4-yl)-amine
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C18H19N3O4
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1
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| 1 |
IC50 = 2800 nM
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CP0446159
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4-N-[(3-methoxyphenyl)methyl]pyrido[4,3-d]pyrimidine-4,7-diamine
Show/Hide
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C15H15N5O
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1
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| 1 |
IC50 = 2870 nM
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CP0477072
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2,2 -Dithiobis(6-methyl-1H-indole-3-propanoic acid)
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C24H24N2O4S2
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1
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| 1 |
IC50 = 2900 nM
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CP0051357
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2-[({8-chloro-4-[(3-chloro-4-fluorophenyl)amino]-3-cyanoquinolin-6-yl}amino)methyl]-1-oxidopyridin-1-ium
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C22H14Cl2FN5O
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1
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| 1 |
IC50 = 2900 nM
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CP0038283
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N-phenyl-6,7,8,9-tetrahydro-5H-pyrimido[4,5-b]indol-4-amine
Show/Hide
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C16H16N4
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1
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| 1 |
IC50 = 3000 nM
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CP0135251
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(3-Chloro-phenyl)-(5,6-diphenyl-7H-pyrrolo[2,3-d]pyrimidin-4-yl)-amine
Show/Hide
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C24H17ClN4
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1
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| 1 |
IC50 = 3000 nM
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CP0460804
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2,2 -Dithiobis(1-methyl-1H-indole-3-propanoic acid)
Show/Hide
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C24H24N2O4S2
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1
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| 1 |
IC50 = 3100 nM
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CP0341422
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8-bromo-4-[(3-chloro-4-fluorophenyl)amino]-6-[(1H-imidazol-4-ylmethyl)amino]quinoline-3-carbonitrile
Show/Hide
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C20H13BrClFN6
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1
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| 1 |
IC50 = 3300 nM
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CP0489768
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N-[3-[(3-ethynylphenyl)carbamoyl]-4-hydroxyphenyl]-N'-hydroxyheptanediamide
Show/Hide
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C22H23N3O5
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1
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| 1 |
IC50 = 3310 nM
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CP0445436
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N-[3-[(3-chloro-4-fluorophenyl)carbamoyl]-4-hydroxyphenyl]-N'-hydroxyheptanediamide
Show/Hide
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C20H21ClFN3O5
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1
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| 1 |
IC50 = 3530 nM
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CP0451024
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4-N-(2-methoxyphenyl)pyrido[4,3-d]pyrimidine-4,7-diamine
Show/Hide
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C14H13N5O
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1
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| 1 |
IC50 = 3710 nM
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CP0510899
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1-{4-[(3-chlorophenyl)amino-6-quinazolinyl}-3-{2-[N-(2-chloroethyl)-N-4-methoxyphenylethylenamine]} triazene
Show/Hide
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C25H25Cl2N7O
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1
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| 1 |
IC50 = 3960 nM
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CP0858355
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4-Methylcarbamoyl-benzenesulfonic acid 2-methoxy-4-(2-nitro-propenyl)-phenyl ester
Show/Hide
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C18H18N2O7S
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1
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| 1 |
IC50 = 4000 nM
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CP0248314
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methyl N-[4-[(6,7-dimethoxyquinazolin-4-yl)amino]-2-methylphenyl]carbamate
Show/Hide
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C19H20N4O4
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1
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| 1 |
IC50 = 4000 nM
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CP0412440
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4-Anilino quinazoline deriv. 6
Show/Hide
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C16H15N3
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1
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| 1 |
IC50 = 4100 nM
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CP0573155
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1-[6-[[2-[(3S,4R)-3-fluoro-4-hydroxy-3-methylpiperidin-1-yl]pyrimidin-4-yl]amino]-4-propan-2-yl-2,7-naphthyridin-1-yl]-N,N-dimethylazetidine-3-carboxamide
Show/Hide
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C27H35FN8O2
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1
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| 1 |
IC50 = 4126 nM
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CP0082252
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2,2 -Dithiobis(1H-indole-3-propanoic acid)
Show/Hide
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C22H20N2O4S2
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1
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| 1 |
IC50 = 4200 nM
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CP0416676
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N'-hydroxy-N-[4-hydroxy-3-[[3-(trifluoromethyl)phenyl]carbamoyl]phenyl]heptanediamide
Show/Hide
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C21H22F3N3O5
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1
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| 1 |
IC50 = 4200 nM
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CP0534253
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2-(5-fluoro-2-hydroxyphenyl)-2-[3-oxo-5-(4-piperazin-1-ylphenyl)-1H-isoindol-2-yl]-N-(1,3-thiazol-2-yl)acetamide
Show/Hide
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C29H26FN5O3S
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1
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| 1 |
IC50 = 4213 nM
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CP0518101
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4-N-[(2-nitrophenyl)methyl]pyrido[4,3-d]pyrimidine-4,7-diamine
Show/Hide
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C14H12N6O2
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1
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| 1 |
IC50 = 4250 nM
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CP0238377
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5-(2,5-dimethoxyphenyl)sulfanyl-9H-pyrimido[4,5-b]indole-2,4-diamine
Show/Hide
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C18H17N5O2S
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1
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| 1 |
IC50 = 4300 nM
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CP0002629
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5,6-Bis-p-tolylamino-isoindole-1,3-dione
Show/Hide
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C22H19N3O2
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1
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| 1 |
IC50 = 4500 nM
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CP0534909
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4-N-[4-(trifluoromethyl)phenyl]pyrido[4,3-d]pyrimidine-4,7-diamine
Show/Hide
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C14H10F3N5
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1
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| 1 |
IC50 = 4700 nM
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CP0771878
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4-Butylcarbamoyl-benzenesulfonic acid 4-(2-nitro-vinyl)-phenyl ester
Show/Hide
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C19H20N2O6S
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1
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| 1 |
IC50 = 4800 nM
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CP0208975
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propan-2-yl N-[4-[(6,7-dimethoxyquinazolin-4-yl)amino]phenyl]carbamate
Show/Hide
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C20H22N4O4
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1
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| 1 |
IC50 = 4800 nM
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CP0518360
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4-N-[4-(dimethylamino)phenyl]pyrido[4,3-d]pyrimidine-4,7-diamine
Show/Hide
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C15H16N6
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1
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| 1 |
IC50 = 4860 nM
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CP0425984
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4-(Benzylamino)quinazoline deriv. 28
Show/Hide
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C16H15N3O
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1
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| 1 |
IC50 = 4900 nM
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CP0411319
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N-[3-[[2-[2-methoxy-4-(1-methylpiperidin-4-yl)anilino]pyrimidin-4-yl]carbamoylamino]phenyl]prop-2-enamide
Show/Hide
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C27H31N7O3
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1
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| 1 |
IC50 = 4999 nM
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CP0464805
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6-nitro-N-phenylquinazolin-4-amine
Show/Hide
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C14H10N4O2
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1
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| 1 |
IC50 = 5000 nM
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CP0255898
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(5Z)-4-(2,3-dihydro-1H-inden-5-ylamino)-5-{[3-methyl-5-(morpholin-4-ylcarbonyl)-1H-pyrrol-2-yl]methylidene}-5H,6H,7H-pyrrolo[2,3-d]pyrimidin-6-one
Show/Hide
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C26H26N6O3
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1
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| 1 |
IC50 = 5000 nM
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CP0202115
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4-[(3-chloro-4-fluorophenyl)amino]-6-[(1H-imidazol-4-ylmethyl)amino]-8-methanesulfinylquinoline-3-carbonitrile
Show/Hide
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C21H16ClFN6OS
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1
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| 1 |
IC50 = 5000 nM
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CP0154293
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ethyl N-[5-[(6,7-dimethoxyquinazolin-4-yl)amino]-2-methylphenyl]carbamate
Show/Hide
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C20H22N4O4
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1
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| 1 |
IC50 = 5000 nM
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CP0281174
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N-[4-(3-chloro-4-fluoroanilino)-7-(4-morpholin-4-ylbutyl)pyrido[3,2-d]pyrimidin-6-yl]prop-2-enamide
Show/Hide
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C24H26ClFN6O2
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1
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| 1 |
IC50 = 5100 nM
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CP0523032
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N-[3-[(3-ethynylphenyl)carbamoyl]-4-methoxyphenyl]-N'-hydroxyheptanediamide
Show/Hide
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C23H25N3O5
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1
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| 1 |
IC50 = 5160 nM
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CP0034842
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4-N-(2-aminophenyl)pyrido[4,3-d]pyrimidine-4,7-diamine
Show/Hide
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C13H12N6
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1
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| 1 |
IC50 = 5250 nM
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CP0201864
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6-(3-(morpholinomethyl)phenyl)-4-((1R,2S)-2-phenylcyclopropylamino)quinoline-3-carbonitrile
Show/Hide
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C30H28N4O
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1
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| 1 |
IC50 = 5260 nM
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CP0543294
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(3S,4R)-3-fluoro-1-[4-[[8-[(2R,3S)-3-hydroxy-2-methylazetidin-1-yl]-5-propan-2-yl-2,7-naphthyridin-3-yl]amino]pyrimidin-2-yl]-3-methylpiperidin-4-ol
Show/Hide
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C25H32FN7O2
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1
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| 1 |
IC50 = 5290 nM
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CP0425025
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4-(2-Amino-ethylcarbamoyl)-benzenesulfonic acid 4-(2-nitro-vinyl)-phenyl ester(HCl)
Show/Hide
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C17H17N3O6S
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1
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| 1 |
IC50 = 5400 nM
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CP0469395
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N-[4-(3-bromo-4-fluoroanilino)-6-(2-pyridin-2-ylethyl)-7H-pyrrolo[2,3-d]pyrimidin-2-yl]-2,2-dimethylpropanamide
Show/Hide
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C24H24BrFN6O
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1
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| 1 |
IC50 = 5400 nM
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CP0363886
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6,7-dimethoxy-N-(3,4,5-trimethoxyphenyl)quinazolin-4-amine
Show/Hide
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C19H21N3O5
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1
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| 1 |
IC50 = 5400 nM
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CP0460738
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N-(3-bromophenyl)quinolin-4-amine
Show/Hide
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C15H11BrN2
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1
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| 1 |
IC50 = 5500 nM
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CP0167790
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4-(4-Bromo-2-fluoroanilino)-6,7-dimethoxyquinazoline
Show/Hide
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C16H13BrFN3O2
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1
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| 1 |
IC50 = 5700 nM
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CP0143944
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propan-2-yl N-[4-[(6,7-dimethoxyquinazolin-4-yl)amino]-2-methylphenyl]carbamate
Show/Hide
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C21H24N4O4
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1
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| 1 |
IC50 = 5800 nM
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CP0536049
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4-(Benzylamino)quinazoline deriv. 32
Show/Hide
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C15H12N4O2
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1
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| 1 |
IC50 = 5900 nM
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CP0505756
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4-N-(4-aminophenyl)pyrido[4,3-d]pyrimidine-4,7-diamine
Show/Hide
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C13H12N6
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1
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| 1 |
IC50 = 5900 nM
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CP0153824
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4-(4-bromo-2-fluorophenoxy)-6,7-dimethoxyquinazoline
Show/Hide
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C16H12BrFN2O3
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1
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| 1 |
IC50 = 5900 nM
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CP0057497
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(3-Chloro-phenyl)-(5-methyl-6-phenyl-7H-pyrrolo[2,3-d]pyrimidin-4-yl)-amine
Show/Hide
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C19H15ClN4
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1
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| 1 |
IC50 = 6000 nM
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CP0268916
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(3-Chloro-phenyl)-(6-methyl-5-phenyl-7H-pyrrolo[2,3-d]pyrimidin-4-yl)-amine
Show/Hide
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C19H15ClN4
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1
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| 1 |
IC50 = 6000 nM
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CP0307525
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N-(3-fluorophenyl)-7-nitroquinazolin-4-amine
Show/Hide
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C14H9FN4O2
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1
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| 1 |
IC50 = 6100 nM
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CP0092894
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methyl N-[2-chloro-4-[(6,7-dimethoxyquinazolin-4-yl)amino]phenyl]carbamate
Show/Hide
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C18H17ClN4O4
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1
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| 1 |
IC50 = 6150 nM
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CP0416677
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N-[3-[(3-ethynylphenyl)carbamoyl]phenyl]-N'-hydroxyheptanediamide
Show/Hide
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C22H23N3O4
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1
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| 1 |
IC50 = 6170 nM
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CP0517306
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butyl N-[2-chloro-4-[(6,7-dimethoxyquinazolin-4-yl)amino]phenyl]carbamate
Show/Hide
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C21H23ClN4O4
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1
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| 1 |
IC50 = 6400 nM
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CP0204538
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N-[3-[[2-[2-methoxy-4-(4-morpholin-4-ylpiperidin-1-yl)anilino]pyrimidin-4-yl]carbamoylamino]phenyl]prop-2-enamide
Show/Hide
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C30H36N8O4
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1
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| 1 |
IC50 = 6463 nM
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CP0467850
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2,3-Dihydro-1-methyl-2-thioxo-1H-indole-3-propanoic Acid
Show/Hide
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C12H13NO2S
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1
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| 1 |
IC50 = 6700 nM
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CP0532389
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2,3-Dihydro-2-thioxo-1H-indole-3-butanoic Acid
Show/Hide
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C12H13NO2S
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1
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| 1 |
IC50 = 6700 nM
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CP0486473
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3-[4-(3-bromoanilino)-6-methoxyquinazolin-7-yl]oxypropyl 3-(prop-2-enyldisulfanyl)propanoate
Show/Hide
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C24H26BrN3O4S2
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1
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| 1 |
IC50 = 6703 nM
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CP0268719
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methyl N-[4-[(6,7-dimethoxyquinazolin-4-yl)amino]phenyl]carbamate
Show/Hide
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C18H18N4O4
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1
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| 1 |
IC50 = 6900 nM
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CP0507771
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2-[1-(4-{4-[2-nitro-(E)-1-ethenyl]phenyloxysulfonyl}phenylcarboxamido)-(1R)-ethylcarboxamido]-(2R)-propanoic acid
Show/Hide
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C21H21N3O9S
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1
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| 1 |
IC50 = 7000 nM
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CP0409675
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4-(Benzylamino)quinazoline deriv. 8
Show/Hide
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C15H12ClN3
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1
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| 1 |
IC50 = 7000 nM
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CP0517305
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propyl N-[4-[(6,7-dimethoxyquinazolin-4-yl)amino]phenyl]carbamate
Show/Hide
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C20H22N4O4
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1
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| 1 |
IC50 = 7050 nM
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CP0110399
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4-Anilino-3-cyanoquinoline deriv. 4
Show/Hide
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C21H21N3O5
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1
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| 1 |
IC50 = 7100 nM
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CP0482027
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methyl N-[5-[(6,7-dimethoxyquinazolin-4-yl)amino]-2-methylphenyl]carbamate
Show/Hide
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C19H20N4O4
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1
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| 1 |
IC50 = 7200 nM
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CP0092896
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butyl N-[4-[(6,7-dimethoxyquinazolin-4-yl)amino]-2-methylphenyl]carbamate
Show/Hide
|
C22H26N4O4
|
1
|
| 1 |
IC50 = 7600 nM
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|
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CP0229749
|
N-[4-[3-bromo-4-[2-(dimethylamino)ethoxy]anilino]quinazolin-6-yl]prop-2-enamide
Show/Hide
|
C21H22BrN5O2
|
1
|
| 1 |
IC50 = 7693 nM
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|
|
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CP0170139
|
5,7-Diamino-2-(3-amino-phenyl)-6-hydroxy-chromen-4-one
Show/Hide
|
C15H13N3O3
|
1
|
| 1 |
IC50 = 7800 nM
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|
|
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CP0138954
|
(E)-2-methoxy-4-(2-nitrovinyl)phenol
Show/Hide
|
C9H9NO4
|
1
|
| 1 |
IC50 = 7900 nM
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|
|
|
CP0419193
|
4-(Benzylamino)quinazoline deriv. 26
Show/Hide
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C15H12N4O2
|
1
|
| 1 |
IC50 = 8000 nM
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|
|
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CP0510010
|
4-N-{[4-(trifluoromethyl)phenyl]methyl}pyrido[4,3-d]pyrimidine-4,7-diamine
Show/Hide
|
C15H12F3N5
|
1
|
| 1 |
IC50 = 8000 nM
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|
|
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CP0221566
|
6-methoxy-4-((1R,2S)-2-phenylcyclopropylamino)quinoline-3-carbonitrile
Show/Hide
|
C20H17N3O
|
1
|
| 1 |
IC50 = 8270 nM
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CP0448919
|
2,2 -Dithiobis(1-methyl-1H-indole-3-butanoic acid)
Show/Hide
|
C26H28N2O4S2
|
1
|
| 1 |
IC50 = 8300 nM
|
|
|
|
CP0170003
|
5-(4-chlorophenyl)sulfanyl-9H-pyrimido[4,5-b]indole-2,4-diamine
Show/Hide
|
C16H12ClN5S
|
1
|
| 1 |
IC50 = 8300 nM
|
|
|
|
CP0555048
|
2,2 -Dithiobis(5-methyl-1H-indole-3-propanoic acid)
Show/Hide
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C24H24N2O4S2
|
1
|
| 1 |
IC50 = 8400 nM
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|
|
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CP0568873
|
(3S,4R)-1-[4-[[8-(azetidin-1-yl)-5-propan-2-yl-2,7-naphthyridin-3-yl]amino]pyrimidin-2-yl]-3-fluoro-3-methylpiperidin-4-ol
Show/Hide
|
C24H30FN7O
|
1
|
| 1 |
IC50 = 8668 nM
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|
|
|
CP0186026
|
6-Amino-2-(4-amino-phenyl)-chromen-4-one
Show/Hide
|
C15H12N2O2
|
1
|
| 1 |
IC50 = 8700 nM
|
|
|
|
CP0423017
|
4-(2-Nitro-vinyl)-benzene-1,2-diol
Show/Hide
|
C8H7NO4
|
1
|
| 1 |
IC50 = 8800 nM
|
|
|
|
CP0009094
|
3-((3-Chlorophenyl)amino)-4,6-diamino-1H-pyrazolo[3,4-d]pyrimidine
Show/Hide
|
C11H10ClN7
|
1
|
| 1 |
IC50 = 9000 nM
|
|
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|
CP0167979
|
4-N-(3-bromophenyl)-6-[(2-methylphenyl)methyl]-7H-pyrrolo[2,3-d]pyrimidine-2,4-diamine
Show/Hide
|
C20H18BrN5
|
2
|
| 1 |
IC50 = 9100 nM
|
|
|
| 2 |
IC50 = 9190 nM
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|
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CP0322685
|
N-(4-bromo-2-fluorophenyl)-6-[2-(diethylamino)ethoxy]-7-methoxyquinazolin-4-amine
Show/Hide
|
C21H24BrFN4O2
|
1
|
| 1 |
IC50 = 9100 nM
|
|
|
|
CP0237627
|
ethyl N-[4-[[6-butoxy-7-[2-(diethylamino)ethoxy]quinazolin-4-yl]amino]-2-chlorophenyl]carbamate
Show/Hide
|
C27H36ClN5O4
|
1
|
| 1 |
IC50 = 9150 nM
|
|
|
|
CP0555033
|
2,2 -Trithiobis( 1H-indole-3-acetic acid)
Show/Hide
|
C20H16N2O4S3
|
1
|
| 1 |
IC50 = 9300 nM
|
|
|
|
CP0504731
|
4-(2-Nitro-propenyl)-benzene-1,2-diol
Show/Hide
|
C9H9NO4
|
1
|
| 1 |
IC50 = 9400 nM
|
|
|
|
CP0073707
|
N-(3-bromo-4-methylphenyl)-7-[2-(diethylamino)ethoxy]-6-methoxyquinazolin-4-amine
Show/Hide
|
C22H27BrN4O2
|
1
|
| 1 |
IC50 = 9450 nM
|
|
|
|
CP0151098
|
N-(3-chloro-4-fluorophenyl)-7-[2-(diethylamino)ethoxy]-6-methoxyquinazolin-4-amine
Show/Hide
|
C21H24ClFN4O2
|
1
|
| 1 |
IC50 = 9900 nM
|
|
|
|
CP0546832
|
(3S,4R)-3-fluoro-3-methyl-1-[4-[[8-[(2R)-2-methylazetidin-1-yl]-5-propan-2-yl-2,7-naphthyridin-3-yl]amino]pyrimidin-2-yl]piperidin-4-ol
Show/Hide
|
C25H32FN7O
|
1
|
| 1 |
IC50 = 9965 nM
|
|
|
|
CP0395895
|
4-(Benzylamino)quinazoline deriv. 9
Show/Hide
|
C16H15N3O
|
1
|
| 1 |
IC50 = 10000 nM
|
|
|
|
CP0425910
|
4-(Benzylamino)quinazoline deriv. 29
Show/Hide
|
C15H12N4O2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0449687
|
4-(Benzylamino)quinazoline deriv. 27
Show/Hide
|
C15H14N4
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0509414
|
N-(3-bromophenyl)cinnolin-4-amine
Show/Hide
|
C14H10BrN3
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0536074
|
4-(Benzylamino)quinazoline deriv. 37
Show/Hide
|
C16H15N3O
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0548556
|
4-Anilinoquinazoline deriv. 50
Show/Hide
|
C14H9BrN4O2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0398528
|
4-(Benzylamino)quinazoline deriv. 35
Show/Hide
|
C15H12N4O2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0535483
|
4-(Benzylamino)quinazoline deriv. 36
Show/Hide
|
C15H14N4
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0409227
|
7-Aminopyrido[4,3-d]pyrimidine 7z
Show/Hide
|
C15H14N6O
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0432312
|
4-N-[(4-aminophenyl)methyl]pyrido[4,3-d]pyrimidine-4,7-diamine
Show/Hide
|
C14H14N6
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0500910
|
4-N-{[2-(trifluoromethyl)phenyl]methyl}pyrido[4,3-d]pyrimidine-4,7-diamine
Show/Hide
|
C15H12F3N5
|
1
|
| 1 |
IC50 = 10000 nM
|
|
|
|
CP0503289
|
4-N-(pyridin-3-yl)pyrido[4,3-d]pyrimidine-4,7-diamine
Show/Hide
|
C12H10N6
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0518268
|
4-N-{[3-(dimethylamino)phenyl]methyl}pyrido[4,3-d]pyrimidine-4,7-diamine
Show/Hide
|
C16H18N6
|
1
|
| 1 |
IC50 = 10000 nM
|
|
|
|
CP0528832
|
4-N-[2-(trifluoromethyl)phenyl]pyrido[4,3-d]pyrimidine-4,7-diamine
Show/Hide
|
C14H10F3N5
|
1
|
| 1 |
IC50 = 10000 nM
|
|
|
|
CP0532347
|
7-Aminopyrido[4,3-d]pyrimidine 7aa
Show/Hide
|
C15H14N6O
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0534874
|
4-N-[(3-aminophenyl)methyl]pyrido[4,3-d]pyrimidine-4,7-diamine
Show/Hide
|
C14H14N6
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0544984
|
4-N-[(4-nitrophenyl)methyl]pyrido[4,3-d]pyrimidine-4,7-diamine
Show/Hide
|
C14H12N6O2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0502152
|
N-(3-bromophenyl)-7,8-dimethoxyquinazolin-4-amine
Show/Hide
|
C16H14BrN3O2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0467457
|
6-nitro-N-[3-(trifluoromethyl)phenyl]quinazolin-4-amine
Show/Hide
|
C15H9F3N4O2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0535297
|
N-(3-bromophenyl)-6,7,8-trimethoxyquinazolin-4-amine
Show/Hide
|
C17H16BrN3O3
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0551556
|
7-nitro-N-[3-(trifluoromethyl)phenyl]quinazolin-4-amine
Show/Hide
|
C15H9F3N4O2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0559847
|
4-[(3-Bromophenyl)amino]-6,7-dimethoxy-2-methylquinazoline Hydrochloride
Show/Hide
|
C17H16BrN3O2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0922319
|
(3-Bromo-phenyl)-(2-methyl-quinazolin-4-yl)-amine
Show/Hide
|
C15H12BrN3
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0095983
|
(1s,3s)-3-(8-amino-1-(2-phenylquinolin-7-yl)imidazo[1,5-a]pyrazin-3-yl)-1-methylcyclobutanol
Show/Hide
|
C26H23N5O
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0065537
|
4-(3-chloro-4-fluorophenoxy)-6,7-dimethoxyquinazoline
Show/Hide
|
C16H12ClFN2O3
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0073673
|
N-[4-[(6,7-dimethoxyquinazolin-4-yl)amino]-2-methylphenyl]pentanamide
Show/Hide
|
C22H26N4O3
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0073708
|
1-butyl-3-(4-(6,7-dimethoxyquinazolin-4-yloxy)phenyl)urea
Show/Hide
|
C21H24N4O4
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0092893
|
N-[4-[(6,7-dimethoxyquinazolin-4-yl)amino]-2-methylphenyl]butanamide
Show/Hide
|
C21H24N4O3
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0092897
|
1-[4-[(6,7-dimethoxyquinazolin-4-yl)amino]phenyl]-3-ethylurea
Show/Hide
|
C19H21N5O3
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0092898
|
1-butyl-3-[4-[(6,7-dimethoxyquinazolin-4-yl)amino]phenyl]urea
Show/Hide
|
C21H25N5O3
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0092900
|
1-[4-[[7-[2-(diethylamino)ethoxy]-6-methoxyquinazolin-4-yl]amino]phenyl]-3-ethylurea
Show/Hide
|
C24H32N6O3
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0092902
|
N-(4-bromo-2-fluorophenyl)-6-butoxy-7-[2-(diethylamino)ethoxy]quinazolin-4-amine
Show/Hide
|
C24H30BrFN4O2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0092904
|
ethyl N-[4-(6,7-dimethoxyquinazolin-4-yl)oxyphenyl]carbamate
Show/Hide
|
C19H19N3O5
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0092907
|
1-(2,4-difluorophenyl)-3-(4-(6,7-dimethoxyquinazolin-4-yloxy)phenyl)urea
Show/Hide
|
C23H18F2N4O4
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0092908
|
1-(3-bromophenyl)-3-[4-(6,7-dimethoxyquinazolin-4-yl)oxyphenyl]urea
Show/Hide
|
C23H19BrN4O4
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0092910
|
1-(4-bromophenyl)-3-[4-(6,7-dimethoxyquinazolin-4-yl)oxy-2-methylphenyl]urea
Show/Hide
|
C24H21BrN4O4
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0110944
|
1-cyclohexyl-3-[4-(6,7-dimethoxyquinazolin-4-yl)oxyphenyl]urea
Show/Hide
|
C23H26N4O4
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0137699
|
methyl N-[4-(6,7-dimethoxyquinazolin-4-yl)oxyphenyl]carbamate
Show/Hide
|
C18H17N3O5
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0146604
|
1-(3-bromophenyl)-3-[4-(6,7-dimethoxyquinazolin-4-yl)oxy-2-methylphenyl]urea
Show/Hide
|
C24H21BrN4O4
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0150675
|
methyl N-[4-[[6-butoxy-7-[2-(diethylamino)ethoxy]quinazolin-4-yl]amino]-2-chlorophenyl]carbamate
Show/Hide
|
C26H34ClN5O4
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0151096
|
N-[4-[(6,7-dimethoxyquinazolin-4-yl)amino]phenyl]propanamide
Show/Hide
|
C19H20N4O3
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0153825
|
1-(3-chloro-4-fluorophenyl)-3-[4-(6,7-dimethoxyquinazolin-4-yl)oxyphenyl]urea
Show/Hide
|
C23H18ClFN4O4
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0153826
|
1-(4-(6,7-dimethoxyquinazolin-4-yloxy)phenyl)-3-(naphthalen-2-yl)urea
Show/Hide
|
C27H22N4O4
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0154294
|
ethyl N-[2-chloro-4-[[7-[2-(diethylamino)ethoxy]-6-methoxyquinazolin-4-yl]amino]phenyl]carbamate
Show/Hide
|
C24H30ClN5O4
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0160938
|
ethyl N-[4-[(6,7-dimethoxyquinazolin-4-yl)amino]phenyl]carbamate
Show/Hide
|
C19H20N4O4
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0171017
|
1-(3-chloro-4-fluorophenyl)-3-(4-(6,7-dimethoxyquinazolin-4-ylamino)phenyl)urea
Show/Hide
|
C23H19ClFN5O3
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0206844
|
1-(3-(6,7-dimethoxyquinazolin-4-yloxy)phenyl)-3-phenylurea
Show/Hide
|
C23H20N4O4
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0219113
|
1-(4-(6,7-dimethoxyquinazolin-4-yloxy)phenyl)-3-phenylurea
Show/Hide
|
C23H20N4O4
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0219184
|
1-(4-(6,7-dimethoxyquinazolin-4-ylamino)phenyl)-3-phenylurea
Show/Hide
|
C23H21N5O3
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0237630
|
ethyl N-[4-[[6-butoxy-7-[2-(diethylamino)ethoxy]quinazolin-4-yl]amino]-2-methylphenyl]carbamate
Show/Hide
|
C28H39N5O4
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0242017
|
1-(3-(6,7-dimethoxyquinazolin-4-yloxy)phenyl)-3-(4-methoxyphenyl)urea
Show/Hide
|
C24H22N4O5
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0248316
|
1-[4-(6,7-Dimethoxy-quinazolin-4-yloxy)-phenyl]-3-(4-methoxy-phenyl)-urea
Show/Hide
|
C24H22N4O5
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0248317
|
1-[4-(6,7-dimethoxyquinazolin-4-yl)oxyphenyl]-3-(3-methoxyphenyl)urea
Show/Hide
|
C24H22N4O5
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0248318
|
1-[4-(6,7-dimethoxyquinazolin-4-yl)oxy-2-methylphenyl]-3-naphthalen-2-ylurea
Show/Hide
|
C28H24N4O4
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0260340
|
1-[4-[(6,7-dimethoxyquinazolin-4-yl)amino]phenyl]-3-(3-methoxyphenyl)urea
Show/Hide
|
C24H23N5O4
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0260341
|
1-(4-bromophenyl)-3-(4-(6,7-dimethoxyquinazolin-4-yloxy)phenyl)urea
Show/Hide
|
C23H19BrN4O4
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0260343
|
1-(3-chloro-4-fluorophenyl)-3-[4-(6,7-dimethoxyquinazolin-4-yl)oxy-2-methylphenyl]urea
Show/Hide
|
C24H20ClFN4O4
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0322654
|
methyl N-[2-chloro-4-[[7-[2-(diethylamino)ethoxy]-6-methoxyquinazolin-4-yl]amino]phenyl]carbamate
Show/Hide
|
C23H28ClN5O4
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0322655
|
ethyl N-[4-[[6-[2-(diethylamino)ethoxy]-7-methoxyquinazolin-4-yl]amino]-2-methylphenyl]carbamate
Show/Hide
|
C25H33N5O4
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0362454
|
methyl N-[4-[[6-butoxy-7-[2-(diethylamino)ethoxy]quinazolin-4-yl]amino]-2-methylphenyl]carbamate
Show/Hide
|
C27H37N5O4
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0400145
|
ethyl N-[4-[[7-[2-(diethylamino)ethoxy]-6-methoxyquinazolin-4-yl]amino]-2-methylphenyl]carbamate
Show/Hide
|
C25H33N5O4
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0400146
|
N-[3-(6,7-dimethoxyquinazolin-4-yl)oxyphenyl]acetamide
Show/Hide
|
C18H17N3O4
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0430758
|
N-(4-bromo-2-fluorophenyl)-7-[2-(diethylamino)ethoxy]-6-methoxyquinazolin-4-amine
Show/Hide
|
C21H24BrFN4O2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0517308
|
methyl N-[4-[[7-[2-(diethylamino)ethoxy]-6-methoxyquinazolin-4-yl]amino]-2-methylphenyl]carbamate
Show/Hide
|
C24H31N5O4
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0412396
|
N-[3-[[2-[4-(diethylamino)-2-methoxyanilino]pyrimidin-4-yl]carbamoylamino]phenyl]prop-2-enamide
Show/Hide
|
C25H29N7O3
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0459275
|
N-[3-[[2-[4-[4-(2-fluoroethyl)piperazin-1-yl]-2-methoxyanilino]pyrimidin-4-yl]carbamoylamino]phenyl]prop-2-enamide
Show/Hide
|
C27H31FN8O3
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0459276
|
N-[3-[[2-(2-methoxy-4-morpholin-4-ylanilino)pyrimidin-4-yl]carbamoylamino]phenyl]prop-2-enamide
Show/Hide
|
C25H27N7O4
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0486082
|
N-[3-[[2-(4-morpholin-4-ylanilino)pyrimidin-4-yl]carbamoylamino]phenyl]prop-2-enamide
Show/Hide
|
C24H25N7O3
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0455869
|
(E)-4-(2-nitrovinyl)phenol
Show/Hide
|
C8H7NO3
|
1
|
| 1 |
IC50 = 10100 nM
|
|
|
|
CP0506220
|
4-N-[(3-nitrophenyl)methyl]pyrido[4,3-d]pyrimidine-4,7-diamine
Show/Hide
|
C14H12N6O2
|
1
|
| 1 |
IC50 = 10100 nM
|
|
|
|
CP0078880
|
4-Dimethylamino-but-2-enoic acid {4-[3-chloro-4-(pyridin-2-ylmethoxy)-phenylamino]-3-cyano-7-ethoxy-quinolin-6-yl}-amide
Show/Hide
|
C30H29ClN6O3
|
1
|
| 1 |
IC50 = 10117 nM
|
|
|
|
CP0475729
|
2,2 -Dithiobis(1H-indole-3-acetic acid)
Show/Hide
|
C20H16N2O4S2
|
1
|
| 1 |
IC50 = 10200 nM
|
|
|
|
CP0269916
|
3-({4-[(3-bromophenyl)amino]pyrido[4,3-d]pyrimidin-7-yl}amino)propanoic acid
Show/Hide
|
C16H14BrN5O2
|
1
|
| 1 |
IC50 = 11400 nM
|
|
|
|
CP0050064
|
US9422297, AAG145-135
Show/Hide
|
C17H12ClFN4
|
1
|
| 1 |
IC50 = 11700 nM
|
|
|
|
CP0454336
|
7-nitro-N-phenylquinazolin-4-amine
Show/Hide
|
C14H10N4O2
|
1
|
| 1 |
IC50 = 12000 nM
|
|
|
|
CP0005596
|
3,4-Di-(phenylamino)-1H-pyrazolo[3,4-d]pyrimidine
Show/Hide
|
C17H14N6
|
1
|
| 1 |
IC50 = 12000 nM
|
|
|
|
CP0391385
|
4-N-(4-chlorophenyl)-6-(naphthalen-1-ylmethyl)-7H-pyrrolo[2,3-d]pyrimidine-2,4-diamine
Show/Hide
|
C23H18ClN5
|
1
|
| 1 |
IC50 = 12620 nM
|
|
|
|
CP0061645
|
4-(3-chloro-4-(3-fluorobenzyloxy)phenylamino)-3-methyl-N-(2-morpholinoethyl)-1H-pyrrolo[3,2-d]pyridazine-2-carboxamide
Show/Hide
|
C27H28ClFN6O3
|
1
|
| 1 |
IC50 = 12650 nM
|
|
|
|
CP0400608
|
2-Amino-4-(m-bromoanilino)-6-(2-methylbenzyl)-7-methyl-pyrrolo[2,3-d]pyrimidine
Show/Hide
|
C21H20BrN5
|
1
|
| 1 |
IC50 = 12800 nM
|
|
|
|
CP0410667
|
2,2-dimethyl-N-[6-(2-pyridin-2-ylethyl)-4-[3-(trifluoromethyl)anilino]-7H-pyrrolo[2,3-d]pyrimidin-2-yl]propanamide
Show/Hide
|
C25H25F3N6O
|
1
|
| 1 |
IC50 = 12800 nM
|
|
|
|
CP0226932
|
2,4-diaminofuro[2,3-d]pyrimidine, 11
Show/Hide
|
C19H24N4O2
|
1
|
| 1 |
IC50 = 13400 nM
|
|
|
|
CP0209132
|
6-Amino-2-(4-amino-phenyl)-7-hydroxy-chromen-4-one
Show/Hide
|
C15H12N2O3
|
1
|
| 1 |
IC50 = 14100 nM
|
|
|
|
CP0492813
|
(2-thioxo-2,3-dihydro-1H-indol-3-yl)acetic acid
Show/Hide
|
C10H9NO2S
|
1
|
| 1 |
IC50 = 14900 nM
|
|
|
|
CP0230209
|
7-(3-chloro-4-(3-fluorobenzyloxy)phenylamino)-N-(2-(pyrrolidin-1-yl)ethyl)-1H-pyrrolo[2,3-d]pyridazine-2-carboxamide
Show/Hide
|
C26H26ClFN6O2
|
1
|
| 1 |
IC50 = 15140 nM
|
|
|
|
CP0385141
|
4-N-[4-fluoro-3-(trifluoromethyl)phenyl]-6-(2-pyridin-2-ylethyl)-7H-pyrrolo[2,3-d]pyrimidine-2,4-diamine
Show/Hide
|
C20H16F4N6
|
1
|
| 1 |
IC50 = 15600 nM
|
|
|
|
CP0500398
|
N-[4-(3-chloro-4-fluoroanilino)-6-(2-pyridin-2-ylethyl)-7H-pyrrolo[2,3-d]pyrimidin-2-yl]-2,2-dimethylpropanamide
Show/Hide
|
C24H24ClFN6O
|
1
|
| 1 |
IC50 = 16300 nM
|
|
|
|
CP0440774
|
1-{4-[1-[1-(2-aminoethylcarbamoyl)-(1R)-ethylcarbamoyl]-(1R)-ethylcarbamoyl]phenylsulfonyloxy}-4-[2-nitro-(E)-1-ethenyl]benzene(HCl)
Show/Hide
|
C23H27N5O8S
|
1
|
| 1 |
IC50 = 17000 nM
|
|
|
|
CP0402171
|
Dimethyl 2,2 -Dithiobis(1H-indole-3-acetate)
Show/Hide
|
C22H20N2O4S2
|
1
|
| 1 |
IC50 = 18000 nM
|
|
|
|
CP0454816
|
2,2 -Dithiobis(1H-indole-3-butanoic acid)
Show/Hide
|
C24H24N2O4S2
|
1
|
| 1 |
IC50 = 18000 nM
|
|
|
|
CP0004567
|
5-(4-Methoxy-phenylamino)-6-phenylamino-isoindole-1,3-dione
Show/Hide
|
C21H17N3O3
|
1
|
| 1 |
IC50 = 18000 nM
|
|
|
|
CP0151567
|
2,4-diaminofuro[2,3-d]pyrimidine, 9
Show/Hide
|
C18H22N4O2
|
1
|
| 1 |
IC50 = 18200 nM
|
|
|
|
CP0426821
|
6-(2-pyridin-2-ylethyl)-4-N-[3-(trifluoromethyl)phenyl]-7H-pyrrolo[2,3-d]pyrimidine-2,4-diamine
Show/Hide
|
C20H17F3N6
|
1
|
| 1 |
IC50 = 19300 nM
|
|
|
|
CP0255972
|
US9422297, AAG145-157
Show/Hide
|
C17H13ClN4
|
1
|
| 1 |
IC50 = 19600 nM
|
|
|
|
CP0417587
|
4-N-(3-ethynylphenyl)-6-(2-pyridin-2-ylethyl)-7H-pyrrolo[2,3-d]pyrimidine-2,4-diamine
Show/Hide
|
C21H18N6
|
1
|
| 1 |
IC50 = 19900 nM
|
|
|
|
CP0221597
|
4-[(3-chloro-4-fluorophenyl)amino]-6-[(1H-imidazol-4-ylmethyl)amino]-8-(trifluoromethyl)quinoline-3-carbonitrile
Show/Hide
|
C21H13ClF4N6
|
1
|
| 1 |
IC50 > 20000 nM
|
|
|
|
CP0316418
|
4-[(3-chloro-4-fluorophenyl)amino]-3-cyano-6-[(1H-imidazol-4-ylmethyl)amino]-N,N-dimethylquinoline-8-carboxamide
Show/Hide
|
C23H19ClFN7O
|
1
|
| 1 |
IC50 > 20000 nM
|
|
|
|
CP0144914
|
4-cycloheptylamino-6-[(pyridin-3-ylmethyl)-amino]-[1,7]naphthyridine-3-carbonitrile
Show/Hide
|
C22H24N6
|
1
|
| 1 |
IC50 > 20000 nM
|
|
|
|
CP0199922
|
5-naphthalen-2-ylsulfanyl-9H-pyrimido[4,5-b]indole-2,4-diamine
Show/Hide
|
C20H15N5S
|
1
|
| 1 |
IC50 = 20000 nM
|
|
|
|
CP0267274
|
5-(4-methoxyphenyl)sulfanyl-9H-pyrimido[4,5-b]indole-2,4-diamine
Show/Hide
|
C17H15N5OS
|
1
|
| 1 |
IC50 = 20800 nM
|
|
|
|
CP0150361
|
1 H-indole-3-alkanamide deriv. 7
Show/Hide
|
C24H24N2O4S2
|
1
|
| 1 |
IC50 = 21000 nM
|
|
|
|
CP0568872
|
(3S,4R)-3-fluoro-3-methyl-1-[4-[[8-(methylamino)-5-propan-2-yl-2,7-naphthyridin-3-yl]amino]pyrimidin-2-yl]piperidin-4-ol
Show/Hide
|
C22H28FN7O
|
1
|
| 1 |
IC50 = 23605 nM
|
|
|
|
CP0091317
|
US9422297, AAG145-131
Show/Hide
|
C17H13BrN4
|
1
|
| 1 |
IC50 = 24100 nM
|
|
|
|
CP0543295
|
(3S,4R)-3-fluoro-1-[4-[[8-(3-methoxyazetidin-1-yl)-5-propan-2-yl-2,7-naphthyridin-3-yl]amino]pyrimidin-2-yl]-3-methylpiperidin-4-ol
Show/Hide
|
C25H32FN7O2
|
1
|
| 1 |
IC50 = 25000 nM
|
|
|
|
CP0545095
|
(3S,4R)-3-fluoro-3-methyl-1-[4-[[8-[(2R)-2-methylazetidin-1-yl]-5-propan-2-yl-2,6-naphthyridin-3-yl]amino]pyrimidin-2-yl]piperidin-4-ol
Show/Hide
|
C25H32FN7O
|
1
|
| 1 |
IC50 = 25000 nM
|
|
|
|
CP0545096
|
(3S,4R)-3-fluoro-3-methyl-1-[4-[[8-[(2S)-2-methylazetidin-1-yl]-5-propan-2-yl-2,7-naphthyridin-3-yl]amino]pyrimidin-2-yl]piperidin-4-ol
Show/Hide
|
C25H32FN7O
|
1
|
| 1 |
IC50 = 25000 nM
|
|
|
|
CP0545097
|
6-[[2-(4-hydroxypiperidin-1-yl)pyrimidin-4-yl]amino]-N-methyl-4-(propan-2-ylamino)pyridine-3-carboxamide
Show/Hide
|
C19H27N7O2
|
1
|
| 1 |
IC50 > 25000 nM
|
|
|
|
CP0546823
|
(3S,4R)-3-fluoro-3-methyl-1-[4-[[4-[(2R)-2-methylazetidin-1-yl]-1-propan-2-ylpyrido[3,4-d]pyridazin-7-yl]amino]pyrimidin-2-yl]piperidin-4-ol
Show/Hide
|
C24H31FN8O
|
1
|
| 1 |
IC50 = 25000 nM
|
|
|
|
CP0546834
|
(3S,4R)-3-fluoro-1-[4-[[8-(methylamino)-5-propan-2-yl-2,7-naphthyridin-3-yl]amino]pyrimidin-2-yl]piperidin-4-ol
Show/Hide
|
C21H26FN7O
|
1
|
| 1 |
IC50 > 25000 nM
|
|
|
|
CP0567944
|
(3S,4R)-3-fluoro-1-[4-[[8-(3-hydroxyazetidin-1-yl)-5-propan-2-yl-2,7-naphthyridin-3-yl]amino]pyrimidin-2-yl]-3-methylpiperidin-4-ol
Show/Hide
|
C24H30FN7O2
|
1
|
| 1 |
IC50 = 25000 nM
|
|
|
|
CP0568870
|
6-[[2-[(3S,4R)-3-fluoro-4-hydroxypiperidin-1-yl]pyrimidin-4-yl]amino]-N-methyl-4-(propan-2-ylamino)pyridine-3-carboxamide
Show/Hide
|
C19H26FN7O2
|
1
|
| 1 |
IC50 > 25000 nM
|
|
|
|
CP0568875
|
(3S,4R)-3-fluoro-1-[4-[[8-[(2R,3S)-3-hydroxy-2-methylazetidin-1-yl]-5-propan-2-ylisoquinolin-3-yl]amino]pyrimidin-2-yl]-3-methylpiperidin-4-ol
Show/Hide
|
C26H33FN6O2
|
1
|
| 1 |
IC50 = 25000 nM
|
|
|
|
CP0568878
|
(3S,4R)-3-fluoro-1-[4-[[8-[(2R,3S)-3-hydroxy-2-methylazetidin-1-yl]-5-propan-2-yl-2,6-naphthyridin-3-yl]amino]pyrimidin-2-yl]-3-methylpiperidin-4-ol
Show/Hide
|
C25H32FN7O2
|
1
|
| 1 |
IC50 = 25000 nM
|
|
|
|
CP0569543
|
1-[6-[[2-[(3S,4R)-3-fluoro-4-hydroxy-3-methylpiperidin-1-yl]pyrimidin-4-yl]amino]-4-propan-2-yl-2,7-naphthyridin-1-yl]-N-methylazetidine-3-carboxamide
Show/Hide
|
C26H33FN8O2
|
1
|
| 1 |
IC50 = 25000 nM
|
|
|
|
CP0571684
|
(3S,4R)-3-fluoro-1-[4-[[8-[3-(methoxymethyl)azetidin-1-yl]-5-propan-2-yl-2,7-naphthyridin-3-yl]amino]pyrimidin-2-yl]-3-methylpiperidin-4-ol
Show/Hide
|
C26H34FN7O2
|
1
|
| 1 |
IC50 = 25000 nM
|
|
|
|
CP0091315
|
US9422297, AAG145-136
Show/Hide
|
C17H13ClN4
|
1
|
| 1 |
IC50 = 26000 nM
|
|
|
|
CP0410664
|
N-[4-[4-fluoro-3-(trifluoromethyl)anilino]-6-(2-pyridin-2-ylethyl)-7H-pyrrolo[2,3-d]pyrimidin-2-yl]-2,2-dimethylpropanamide
Show/Hide
|
C25H24F4N6O
|
1
|
| 1 |
IC50 = 26900 nM
|
|
|
|
CP0099872
|
4-Anilinoquinoline deriv. 8
Show/Hide
|
C20H22N2O5
|
1
|
| 1 |
IC50 = 27000 nM
|
|
|
|
CP0391012
|
6-[(2,4-dichlorophenyl)methyl]-4-N-[3-(trifluoromethyl)phenyl]-7H-pyrrolo[2,3-d]pyrimidine-2,4-diamine
Show/Hide
|
C20H14Cl2F3N5
|
1
|
| 1 |
IC50 = 27200 nM
|
|
|
|
CP0476570
|
N-[5-chloro-4-(3-fluoroanilino)-9H-pyrimido[4,5-b]indol-2-yl]-2,2-dimethylpropanamide
Show/Hide
|
C21H19ClFN5O
|
1
|
| 1 |
IC50 = 30800 nM
|
|
|
|
CP0428721
|
2-Amino-4-(N-methyl-m-bromoanilino)-6-(2-methylbenzyl)-pyrrolo[2,3-d]pyrimidine
Show/Hide
|
C21H20BrN5
|
1
|
| 1 |
IC50 = 31200 nM
|
|
|
|
CP0470452
|
Dimethyl 2,2 -Dithiobis(1-methyl-1H-indole-3-acetate)
Show/Hide
|
C24H24N2O4S2
|
1
|
| 1 |
IC50 = 33000 nM
|
|
|
|
CP0391016
|
6-(2,4-dichlorobenzyl)-N-(3-(trifluoromethyl)phenyl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine
Show/Hide
|
C20H13Cl2F3N4
|
1
|
| 1 |
IC50 = 33100 nM
|
|
|
|
CP0467843
|
Dimethyl 2,2 -Trithiobis(1H-indole-3-acetate)
Show/Hide
|
C22H20N2O4S3
|
1
|
| 1 |
IC50 = 35000 nM
|
|
|
|
CP0008693
|
3-((3-Chlorophenyl)amino)-4-amino-1H-pyrazolo[3,4-d]pyrimidine
Show/Hide
|
C11H9ClN6
|
1
|
| 1 |
IC50 = 35000 nM
|
|
|
|
CP0476571
|
5-chloro-4-N-(4-chloro-2-fluorophenyl)-9H-pyrimido[4,5-b]indole-2,4-diamine
Show/Hide
|
C16H10Cl2FN5
|
1
|
| 1 |
IC50 = 38900 nM
|
|
|
|
CP0417729
|
N-[5-chloro-4-(4-propan-2-ylanilino)-9H-pyrimido[4,5-b]indol-2-yl]-2,2-dimethylpropanamide
Show/Hide
|
C24H26ClN5O
|
1
|
| 1 |
IC50 = 39200 nM
|
|
|
|
CP0534464
|
tert-butyl (2R)-2-[[(2R)-2-[[4-[4-[(E)-2-nitroethenyl]phenoxy]sulfonylbenzoyl]amino]propanoyl]amino]propanoate
Show/Hide
|
C25H29N3O9S
|
1
|
| 1 |
IC50 = 40000 nM
|
|
|
|
CP0427361
|
4-(1,1-dimethylpropylamino)-6-[(pyridin-3-ylmethyl)amino]-[1,7]naphthyridine-3-carbonitrile
Show/Hide
|
C20H22N6
|
1
|
| 1 |
IC50 > 40000 nM
|
|
|
|
CP0445399
|
4-tert-butylamino-6-[(pyridin-3-ylmethyl)-amino]-[1,7]naphthyridine-3-carbonitrile
Show/Hide
|
C19H20N6
|
1
|
| 1 |
IC50 > 40000 nM
|
|
|
|
CP0454983
|
4-cyclopentylamino-6-[(pyridin-3-ylmethyl)-amino]-[1,7]naphthyridine-3-carbonitrile
Show/Hide
|
C20H20N6
|
1
|
| 1 |
IC50 > 40000 nM
|
|
|
|
CP0454984
|
4-cyclohexylamino-6-[(pyridin-3-ylmethyl)-amino]-[1,7]naphthyridine-3-carbonitrile
Show/Hide
|
C21H22N6
|
1
|
| 1 |
IC50 > 40000 nM
|
|
|
|
CP0509312
|
4-cyclopropylamino-6-[(pyridin-3-ylmethyl)-amino]-[1,7]naphthyridine-3-carbonitrile
Show/Hide
|
C18H16N6
|
1
|
| 1 |
IC50 > 40000 nM
|
|
|
|
CP0522588
|
5-chloro-4-N-(4-propan-2-ylphenyl)-9H-pyrimido[4,5-b]indole-2,4-diamine
Show/Hide
|
C19H18ClN5
|
1
|
| 1 |
IC50 = 42000 nM
|
|
|
|
CP0160645
|
US9422297, AAG145-126
Show/Hide
|
C20H20N4
|
1
|
| 1 |
IC50 = 42600 nM
|
|
|
|
CP0493546
|
6-[(2,4-dichlorophenyl)methyl]-4-N-(4-propan-2-ylphenyl)-7H-pyrrolo[2,3-d]pyrimidine-2,4-diamine
Show/Hide
|
C22H21Cl2N5
|
1
|
| 1 |
IC50 = 45600 nM
|
|
|
|
CP0923127
|
1-(4-{1-[1-(2-carboxy tertbutyl aminoethylcarbamoyl)ethylcarbamoyl]ethylcarbamoyl}phenylsulfonyloxy)-4-[2-nitro-(E)-1-ethenyl]benzene
Show/Hide
|
C28H35N5O10S
|
1
|
| 1 |
IC50 > 50000 nM
|
|
|
|
CP0001999
|
2-Methyl-5,6-bis-phenylamino-isoindole-1,3-dione
Show/Hide
|
C21H17N3O2
|
1
|
| 1 |
IC50 > 50000 nM
|
|
|
|
CP0004248
|
N-(6-anilino-1,3-dioxoisoindol-5-yl)-N-phenylacetamide
Show/Hide
|
C22H17N3O3
|
1
|
| 1 |
IC50 > 50000 nM
|
|
|
|
CP0006203
|
2-Phenyl-5,6-bis-phenylamino-isoindole-1,3-dione
Show/Hide
|
C26H19N3O2
|
1
|
| 1 |
IC50 > 50000 nM
|
|
|
|
CP0039638
|
2,4-diaminofuro[2,3-d]pyrimidine, 1a
Show/Hide
|
C16H16N4O2
|
1
|
| 1 |
IC50 > 50000 nM
|
|
|
|
CP0392884
|
4-N-(4-chloro-2-fluorophenyl)-6-[(2-methylphenyl)methyl]-7H-pyrrolo[2,3-d]pyrimidine-2,4-diamine
Show/Hide
|
C20H17ClFN5
|
1
|
| 1 |
IC50 > 50000 nM
|
|
|
|
CP0064002
|
2-[4-(1,3-benzothiazol-5-ylamino)-6-tert-butylsulfonylquinazolin-7-yl]oxyethanol
Show/Hide
|
C21H22N4O4S2
|
1
|
| 1 |
IC50 > 50000 nM
|
|
|
|
CP0180537
|
2-methyl-6-(trifluoromethyl)-N-(3,4,5-trimethoxyphenyl)quinolin-4-amine
Show/Hide
|
C20H19F3N2O3
|
1
|
| 1 |
IC50 > 50000 nM
|
|
|
|
CP0180553
|
6-bromo-N-(3,4,5-trimethoxyphenyl)quinolin-4-amine
Show/Hide
|
C18H17BrN2O3
|
1
|
| 1 |
IC50 > 50000 nM
|
|
|
|
CP0245015
|
6-(trifluoromethyl)-N-(3,4,5-trimethoxyphenyl)quinolin-4-amine
Show/Hide
|
C19H17F3N2O3
|
1
|
| 1 |
IC50 > 50000 nM
|
|
|
|
CP0313585
|
6-(trifluoromethyl)-N-(3,4,5-trimethoxyphenyl)quinazolin-4-amine
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C18H16F3N3O3
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1
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| 1 |
IC50 > 50000 nM
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CP0528950
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2,2 -Dithiobis(1-methyl-1H-indole-3-acetic acid)
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C22H20N2O4S2
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1
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| 1 |
IC50 = 53000 nM
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CP0497232
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2-Amino-4-(N-methyl-m-bromoanilino)-6-benzyl-pyrrolo[2,3-d]pyrimidine
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C20H18BrN5
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1
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| 1 |
IC50 = 53100 nM
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CP0400033
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6-[(2,4-dichlorophenyl)methyl]-4-N-(3-ethynylphenyl)-7H-pyrrolo[2,3-d]pyrimidine-2,4-diamine
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C21H15Cl2N5
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1
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| 1 |
IC50 = 55200 nM
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CP0060431
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2,4-diaminofuro[2,3-d]pyrimidine, 10
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C18H20N4O2
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1
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| 1 |
IC50 = 56500 nM
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CP0431280
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N-[5-chloro-4-(4-chloroanilino)-9H-pyrimido[4,5-b]indol-2-yl]-2,2-dimethylpropanamide
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C21H19Cl2N5O
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1
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| 1 |
IC50 = 58700 nM
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CP0417730
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5-chloro-4-N-(4-chlorophenyl)-9H-pyrimido[4,5-b]indole-2,4-diamine
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C16H11Cl2N5
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1
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| 1 |
IC50 = 63600 nM
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CP0500979
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4-N-(4-nitrophenyl)pyrido[4,3-d]pyrimidine-4,7-diamine
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C13H10N6O2
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1
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| 1 |
IC50 = 65000 nM
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CP0397959
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4-N-[2-(dimethylamino)phenyl]pyrido[4,3-d]pyrimidine-4,7-diamine
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C15H16N6
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1
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| 1 |
IC50 = 69000 nM
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CP0440043
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4-N-(3-bromophenyl)-7-[(2,5-dimethoxyphenyl)methyl]pyrrolo[2,3-d]pyrimidine-2,4-diamine
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C21H20BrN5O2
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1
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| 1 |
IC50 = 69200 nM
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CP0317818
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7-(3-chloro-4-(3-fluorobenzyloxy)phenylamino)-N-(2-(diethylamino)ethyl)-1H-pyrrolo[2,3-d]pyridazine-2-carboxamide
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C26H28ClFN6O2
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1
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| 1 |
IC50 = 77220 nM
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CP0437093
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(3,4-Dimethoxy-phenyl)-(6,7-dimethoxy-quinolin-4-yl)-amine
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C19H20N2O4
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1
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| 1 |
IC50 = 80500 nM
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CP0473414
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5-chloro-4-N-(3-methoxyphenyl)-9H-pyrimido[4,5-b]indole-2,4-diamine
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C17H14ClN5O
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1
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| 1 |
IC50 = 82900 nM
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CP0417588
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4-N-(3-bromo-4-fluorophenyl)-6-(2-pyridin-2-ylethyl)-7H-pyrrolo[2,3-d]pyrimidine-2,4-diamine
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C19H16BrFN6
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1
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| 1 |
IC50 = 85900 nM
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CP0401378
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6-[(2,4-dichlorophenyl)methyl]-4-N-[3-fluoro-4-(trifluoromethyl)phenyl]-7H-pyrrolo[2,3-d]pyrimidine-2,4-diamine
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C20H13Cl2F4N5
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1
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| 1 |
IC50 = 91700 nM
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CP0454238
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6-[(2,4-dichlorophenyl)methyl]-4-N-(2-propan-2-ylphenyl)-7H-pyrrolo[2,3-d]pyrimidine-2,4-diamine
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C22H21Cl2N5
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1
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| 1 |
IC50 = 96400 nM
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CP0402192
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4-N-(3-bromophenyl)-7-[(4-chlorophenyl)methyl]pyrrolo[2,3-d]pyrimidine-2,4-diamine
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C19H15BrClN5
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1
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| 1 |
IC50 = 99900 nM
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CP0525419
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4-Butylcarbamoyl-benzenesulfonic acid 4-formyl-phenyl ester
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C18H19NO5S
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1
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| 1 |
IC50 > 100000 nM
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CP0400983
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2-thioxo-1H-indole-3-alkanoic acid deriv. 19
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C20H25NO6S
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1
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| 1 |
IC50 > 100000 nM
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CP0403662
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Dimethyl 2,2 -Dithiobis(1H-indole-3-butanoate)
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C26H28N2O4S2
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1
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| 1 |
IC50 > 100000 nM
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CP0425938
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2-thioxo-1H-indole-3-alkanoic acid deriv. 18
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C16H19NO4S
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1
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| 1 |
IC50 > 100000 nM
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CP0433106
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2-thioxo-1H-indole-3-alkanoic acid deriv. 15
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C13H15NO2S
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1
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| 1 |
IC50 > 100000 nM
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CP0460673
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2-thioxo-1H-indole-3-alkanoic acid deriv. 7
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C11H11NO2S
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1
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| 1 |
IC50 = 100000 nM
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CP0463307
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2-thioxo-1H-indole-3-alkanoic acid deriv. 12
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C13H15NO2S
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1
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| 1 |
IC50 > 100000 nM
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CP0476599
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2,3-Dihydro-1-methyl-2-thioxo-1H-indole-3-acetic Acid
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C11H11NO2S
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1
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| 1 |
IC50 > 100000 nM
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CP0476900
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2-thioxo-1H-indole-3-alkanoic acid deriv. 11
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C12H13NO2S
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1
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| 1 |
IC50 > 100000 nM
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CP0477039
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methyl 3-[2-[[3-(3-methoxy-3-oxopropyl)-1-methylindol-2-yl]disulfanyl]-1-methylindol-3-yl]propanoate
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C26H28N2O4S2
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1
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| 1 |
IC50 > 100000 nM
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CP0481448
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2-thioxo-1H-indole-3-alkanoic acid deriv. 16
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C14H17NO2S
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1
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| 1 |
IC50 > 100000 nM
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CP0495458
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Dimethyl 2,2 -Thiobis(1-methyl-1H-indole-3-acetate)
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C24H24N2O4S
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1
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| 1 |
IC50 > 100000 nM
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CP0530019
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2,3-Dihydro-1-methyl-2-thioxo-1H-indole-3-butanoic Acid
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C13H15NO2S
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1
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| 1 |
IC50 > 100000 nM
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CP0541021
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Dimethyl 2,2 -Dithiobis(1-methyl-1H-indole-3-butanoate)
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C28H32N2O4S2
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1
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| 1 |
IC50 > 100000 nM
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CP0554707
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2-thioxo-1H-indole-3-alkanoic acid deriv. 17
Show/Hide
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C14H15NO4S
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1
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| 1 |
IC50 > 100000 nM
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CP0555144
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2-thioxo-1H-indole-3-alkanoic acid deriv. 8
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C12H13NO2S
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1
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| 1 |
IC50 > 100000 nM
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CP0082277
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8-Amino-2-(4-amino-phenyl)-chromen-4-one
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C15H12N2O2
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1
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| 1 |
IC50 > 100000 nM
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CP0082471
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6-Amino-2-(3-amino-phenyl)-7-hydroxy-chromen-4-one
Show/Hide
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C15H12N2O3
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1
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| 1 |
IC50 > 100000 nM
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CP0088622
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5,7-Diamino-2-(4-amino-phenyl)-6-hydroxy-chromen-4-one
Show/Hide
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C15H13N3O3
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1
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| 1 |
IC50 > 100000 nM
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CP0100292
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8-Amino-2-(4-amino-phenyl)-7-hydroxy-chromen-4-one
Show/Hide
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C15H12N2O3
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1
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| 1 |
IC50 > 100000 nM
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CP0100359
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8-Amino-2-(4-amino-phenyl)-6-hydroxy-chromen-4-one
Show/Hide
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C15H12N2O3
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1
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| 1 |
IC50 > 100000 nM
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CP0141620
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8-Amino-2-(4-amino-phenyl)-5-methoxy-chromen-4-one
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C16H14N2O3
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1
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| 1 |
IC50 > 100000 nM
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CP0215712
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8-Amino-2-(4-amino-phenyl)-5-hydroxy-chromen-4-one
Show/Hide
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C15H12N2O3
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1
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| 1 |
IC50 > 100000 nM
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CP0286063
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6,8-Diamino-2-(4-amino-phenyl)-chromen-4-one
Show/Hide
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C15H13N3O2
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1
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| 1 |
IC50 > 100000 nM
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CP0286123
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8-Amino-2-(4-amino-phenyl)-6-methoxy-chromen-4-one
Show/Hide
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C16H14N2O3
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1
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| 1 |
IC50 > 100000 nM
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CP0286125
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8-Amino-2-(3-amino-phenyl)-6-methoxy-chromen-4-one
Show/Hide
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C16H14N2O3
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1
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| 1 |
IC50 > 100000 nM
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CP0303015
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6,8-Diamino-2-(4-amino-phenyl)-7-hydroxy-chromen-4-one
Show/Hide
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C15H13N3O3
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1
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| 1 |
IC50 > 100000 nM
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CP0324121
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6-Amino-2-(3-amino-phenyl)-chromen-4-one
Show/Hide
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C15H12N2O2
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1
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| 1 |
IC50 > 100000 nM
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CP0805975
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6-Amino-2-(4-amino-phenyl)-5-hydroxy-chromen-4-one
Show/Hide
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C15H12N2O3
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1
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| 1 |
IC50 > 100000 nM
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CP0000570
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5-(Methyl-phenyl-amino)-6-phenylamino-isoindole-1,3-dione
Show/Hide
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C21H17N3O2
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1
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| 1 |
IC50 > 100000 nM
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CP0012028
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5,6-Bis-(4-methoxy-phenylamino)-isoindole-1,3-dione
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C22H19N3O4
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1
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| 1 |
IC50 > 100000 nM
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CP0012231
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5,6-Bis-(biphenyl-4-ylamino)-isoindole-1,3-dione
Show/Hide
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C32H23N3O2
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1
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| 1 |
IC50 > 100000 nM
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CP0409702
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N-(3-bromophenyl)quinoxalin-2-amine
Show/Hide
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C14H10BrN3
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1
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| 1 |
IC50 > 100000 nM
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CP0445338
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N-(3-bromophenyl)isoquinolin-1-amine
Show/Hide
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C15H11BrN2
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1
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| 1 |
IC50 > 100000 nM
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CP0502115
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N-(3-bromophenyl)phthalazin-1-amine
Show/Hide
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C14H10BrN3
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1
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| 1 |
IC50 > 100000 nM
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CP0537145
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4-Anilino quinazoline deriv. 11
Show/Hide
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C15H13N3
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1
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| 1 |
IC50 = 100000 nM
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CP0412473
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4-N-[(2-methoxyphenyl)methyl]pyrido[4,3-d]pyrimidine-4,7-diamine
Show/Hide
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C15H15N5O
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1
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| 1 |
IC50 = 100000 nM
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CP0415641
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4-N-{[2-(dimethylamino)phenyl]methyl}pyrido[4,3-d]pyrimidine-4,7-diamine
Show/Hide
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C16H18N6
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1
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| 1 |
IC50 > 100000 nM
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CP0500926
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4-N-{[4-(dimethylamino)phenyl]methyl}pyrido[4,3-d]pyrimidine-4,7-diamine
Show/Hide
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C16H18N6
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1
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| 1 |
IC50 > 100000 nM
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CP0531431
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4-N-[(4-methoxyphenyl)methyl]pyrido[4,3-d]pyrimidine-4,7-diamine
Show/Hide
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C15H15N5O
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1
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| 1 |
IC50 > 100000 nM
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CP0045154
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(5,6-Dimethyl-7H-pyrrolo[2,3-d]pyrimidin-4-yl)-m-tolyl-amine
Show/Hide
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C15H16N4
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1
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| 1 |
IC50 > 100000 nM
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CP0045168
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(5,6-Dimethyl-7H-pyrrolo[2,3-d]pyrimidin-4-yl)-(3-fluoro-phenyl)-amine
Show/Hide
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C14H13FN4
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1
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| 1 |
IC50 > 100000 nM
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CP0047417
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(6,7,8,9-Tetrahydro-5H-pyrimido[4,5-b]indol-4-yl)-m-tolyl-amine
Show/Hide
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C17H18N4
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1
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| 1 |
IC50 > 100000 nM
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CP0112109
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(5,6-Dimethyl-7H-pyrrolo[2,3-d]pyrimidin-4-yl)-phenyl-amine
Show/Hide
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C14H14N4
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1
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| 1 |
IC50 > 100000 nM
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CP0007620
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3-((4-(N-BOC-amino)phenyl)amino)-4-((3-chlorophenyl)amino)-1H-pyrazolo[3,4-d]pyrimidine
Show/Hide
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C22H22ClN7O2
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1
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| 1 |
IC50 > 100000 nM
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CP0008024
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4-(3-chlorophenoxy)-N-(3-chlorophenyl)-1H-pyrazolo[3,4-d]pyrimidin-3-amine
Show/Hide
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C17H11Cl2N5O
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1
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| 1 |
IC50 > 100000 nM
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CP0011195
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3-(3-Nitrophenyl)-4-((3-chlorophenyl)amino)-1H-pyrazolo[3,4-d]pyrimidine
Show/Hide
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C17H11ClN6O2
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1
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| 1 |
IC50 > 100000 nM
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CP0011819
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4-(3,4-Dimethoxy-phenoxy)-6,7-dimethoxy-quinoline
Show/Hide
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C19H19NO5
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1
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| 1 |
IC50 > 100000 nM
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CP0461353
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4-(3,4-Dimethoxy-phenoxy)-6,7-dimethoxy-quinazoline
Show/Hide
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C18H18N2O5
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1
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| 1 |
IC50 > 100000 nM
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CP0509792
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4-[(Phenylmethyl)amino]-pyrido[2,3-d]pyrimidine
Show/Hide
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C14H12N4
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1
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| 1 |
IC50 > 10 nM
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CP0415600
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5-methyl-N-(4-nitrophenyl)furo[2,3-d]pyrimidin-4-amine
Show/Hide
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C13H10N4O3
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1
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| 1 |
IC50 > 200 nM
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CP0415602
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1-N-methyl-4-N-(5-methylfuro[2,3-d]pyrimidin-4-yl)benzene-1,4-diamine
Show/Hide
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C14H14N4O
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1
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| 1 |
IC50 > 200 nM
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CP0517581
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4-N,4-N-dimethyl-1-N-(5-methylfuro[2,3-d]pyrimidin-4-yl)benzene-1,4-diamine
Show/Hide
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C15H16N4O
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1
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| 1 |
IC50 > 200 nM
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CP0517582
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N,5-dimethyl-N-(4-nitrophenyl)furo[2,3-d]pyrimidin-4-amine
Show/Hide
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C14H12N4O3
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1
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| 1 |
IC50 > 200 nM
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CP0137242
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4-Anilinopyrido[3,4-d]pyrimidine 35
Show/Hide
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C15H11BrN4O2S
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1
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| 1 |
IC50 > 500 nM
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CP0358794
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(2E)-3-({4-[(3-bromophenyl)amino]quinazolin-6-yl}carbamoyl)prop-2-enoic acid
Show/Hide
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C18H13BrN4O3
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1
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| 1 |
IC50 > 500 nM
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CP0418650
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N,2,6-trimethyl-N-(3,4,5-trimethoxyphenyl)furo[2,3-d]pyrimidin-4-amine
Show/Hide
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C18H21N3O4
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1
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| 1 |
IC50 > 500 nM
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CP0488677
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4-(5-methoxyindol-1-yl)-2,6-dimethylfuro[2,3-d]pyrimidine
Show/Hide
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C17H15N3O2
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1
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| 1 |
IC50 > 500 nM
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CP0504741
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N-(4-ethoxyphenyl)-N,2,6-trimethylfuro[2,3-d]pyrimidin-4-amine
Show/Hide
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C17H19N3O2
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1
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| 1 |
IC50 > 500 nM
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CP0002883
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3-((3-Chlorophenyl)amino)-4-((3-bromophenyl)amino)-1H-pyrazolo[3,4-d]pyrimidine
Show/Hide
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C17H12BrClN6
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1
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| 1 |
IC50 < 800 nM
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CP0437305
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4-[(3-Bromophenyl)amino]-1,2,3-benzotriazine
Show/Hide
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C13H9BrN4
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1
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| 1 |
IC50 > 1000 nM
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CP0510114
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4-(Benzylamino)quinazoline deriv. 33
Show/Hide
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C15H14N4
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1
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| 1 |
IC50 > 1000 nM
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CP0529869
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4-Anilino quinazoline deriv. 18
Show/Hide
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C13H10N4
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1
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| 1 |
IC50 > 1000 nM
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CP0196249
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2-({4-[(3-bromophenyl)amino]pyrido[4,3-d]pyrimidin-7-yl}amino)ethane-1-sulfonic acid
Show/Hide
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C15H14BrN5O3S
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1
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| 1 |
IC50 > 1000 nM
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CP0311192
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4-[(3-Bromophenyl)amino]-7-[[3-(4-morpholino)propyl]amino]pyrido[4,3-d]pyrimidine N1 -Oxide
Show/Hide
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C20H23BrN6O2
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1
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| 1 |
IC50 > 1000 nM
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CP0329855
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(E)-N-[4-(3-Chloro-4-fluorophenylamino)-3-cyano-7-ethoxyquinolin-6-yl]-3-[1-(2-fluoroethyl)-1H-[1,2,3]triazol-4-yl]-acrylamide
Show/Hide
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C25H20ClF2N7O2
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1
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| 1 |
IC50 > 1000 nM
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CP0147108
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N-(3-bromophenyl)-11,17-dioxa-14-thia-4,6-diazatricyclo[8.7.0.03,8]heptadeca-1(10),2,4,6,8-pentaen-7-amine
Show/Hide
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C18H16BrN3O2S
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1
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| 1 |
IC50 > 1000 nM
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CP0166007
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N-(3-bromophenyl)-2,10-dioxa-6-thia-14,16-diazatricyclo[9.8.0.013,18]nonadeca-1(11),12,14,16,18-pentaen-17-amine
Show/Hide
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C20H20BrN3O2S
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1
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| 1 |
IC50 > 1000 nM
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CP0006394
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4,5-dianilinophthalimide
Show/Hide
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C20H15N3O2
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1
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| 1 |
IC50 > 4500 nM
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CP0358290
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5-{[(5Z)-4-[(3-chloro-4-fluorophenyl)amino]-6-oxo-5H,6H,7H-pyrrolo[2,3-d]pyrimidin-5-ylidene]methyl}-4-methyl-1H-pyrrole-2-carboxylic acid
Show/Hide
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C19H13ClFN5O3
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1
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| 1 |
IC50 > 5000 nM
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CP0051398
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8-bromo-4-[(3-chloro-4-fluorophenyl)amino]-6-[(1H-1,2,3-triazol-4-ylmethyl)amino]quinoline-3-carbonitrile
Show/Hide
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C19H12BrClFN7
|
1
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| 1 |
IC50 > 5000 nM
|
|
|
|
CP0198149
|
8-bromo-4-[(3-chloro-4-fluorophenyl)amino]-6-[({1-[3-(dimethylamino)propyl]-1H-1,2,3-triazol-4-yl}methyl)amino]quinoline-3-carbonitrile
Show/Hide
|
C24H23BrClFN8
|
1
|
| 1 |
IC50 > 5000 nM
|
|
|
|
CP0277537
|
8-chloro-4-[(3-chloro-4-fluorophenyl)amino]-6-[(pyridin-3-ylmethyl)amino]quinoline-3-carbonitrile
Show/Hide
|
C22H14Cl2FN5
|
1
|
| 1 |
IC50 > 5000 nM
|
|
|
|
CP0015837
|
4-(3-chloro-4-fluorophenylamino)-6-(pyridin-3-ylmethylamino)-1,7-naphthyridine-3-carbonitrile
Show/Hide
|
C21H14ClFN6
|
1
|
| 1 |
IC50 < 5000 nM
|
|
|
|
CP0955658
|
4-phenylamino-6-[(pyridin-3-ylmethyl)-amino]-[1,7]naphthyridine-3-carbonitrile
Show/Hide
|
C21H16N6
|
1
|
| 1 |
IC50 < 5000 nM
|
|
|
