Brief Information of the Compound and Protein
Compound Name
N-(3-bromophenyl)-11,17-dioxa-14-thia-4,6-diazatricyclo[8.7.0.03,8]heptadeca-1(10),2,4,6,8-pentaen-7-amine
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PubChem ID
CID: 70695327
SID: 163437525
Canonical SMILES
Brc1cccc(Nc2ncnc3cc4OCCSCCOc4cc23)c1
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Compound Formula C18H16BrN3O2S
Compound Structure
Protein Name
Epidermal growth factor receptor
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase EGFR family
Uniprot ID
P00533
Gene Name
EGFR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000052 A-431 Homo sapiens (Human)  1
1
IC50 > 1000 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 7 nM