Brief Information of the Compound and Protein
Compound Name
5,6-Bis-(4-fluoro-phenylamino)-isoindole-1,3-dione
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PubChem ID
CID: 6711154
SID: 12014958
Canonical SMILES
Fc1ccc(Nc2cc3C(=O)NC(=O)c3cc2Nc2ccc(F)cc2)cc1
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Compound Formula C20H13F2N3O2
Compound Structure
Protein Name
Epidermal growth factor receptor
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase EGFR family
Uniprot ID
P00533
Gene Name
EGFR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000052 A-431 Homo sapiens (Human)  1
1
IC50 = 2200 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 700 nM