Brief Information of the Compound and Protein
Compound Name
3-({4-[(3-bromophenyl)amino]pyrido[4,3-d]pyrimidin-7-yl}amino)propanoic acid
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PubChem ID
CID: 5328322
SID: 15625658
Canonical SMILES
OC(=O)CCNc1cc2ncnc(Nc3cccc(Br)c3)c2cn1
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Compound Formula C16H14BrN5O2
Compound Structure
Protein Name
Epidermal growth factor receptor
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
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TK protein kinase group
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Tyrosine protein kinase EGFR family
Uniprot ID
P00533
Gene Name
EGFR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000052 A-431 Homo sapiens (Human)  1
1
IC50 = 11400 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 0.6026 nM
2 IC50 = 0.61 nM