Brief Information of the Compound and Protein
Compound Name
N-(3-bromophenyl)-2,10-dioxa-6-thia-14,16-diazatricyclo[9.8.0.013,18]nonadeca-1(11),12,14,16,18-pentaen-17-amine
    Show/Hide
PubChem ID
CID: 10288283
SID: 15294242
Canonical SMILES
Brc1cccc(Nc2ncnc3cc4OCCCSCCCOc4cc23)c1
    Show/Hide
Compound Formula C20H20BrN3O2S
Compound Structure
Protein Name
Epidermal growth factor receptor
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase EGFR family
Uniprot ID
P00533
Gene Name
EGFR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000052 A-431 Homo sapiens (Human)  1
1
IC50 > 1000 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 8 nM