Brief Information of the Compound and Protein
Compound Name
 Compound Info 
ACP-196
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 PubChem ID
CID: 71226662
Canonical SMILES
CC#CC(=O)N1CCC[C@H]1c1nc(-c2ccc(cc2)C(=O)Nc2ccccn2)c2c(N)nccn12
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Compound Formula C26H23N7O2
Compound Structure
Protein Name
 Protein Info 
Epidermal growth factor receptor
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase EGFR family
Uniprot ID
P00533
Gene Name
EGFR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000052 A-431
 Cell Line Info 
Homo sapiens (Human)  1
1
EC50 > 1000 nM
   TI
   LI
   LO
   TS
CL000012 Sf21
 Cell Line Info 
Spodoptera frugiperda (Fall armyworm)  1
1
IC50 = 3513 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 > 1000 nM
2 IC50 > 10000 nM
3 Kd = 170 nM
4 Kd = 5600 nM