Brief Information of the Compound and Protein
Compound Name
ethyl 4-[3-chloro-4-[(3-fluorophenyl)methoxy]anilino]-7-methyl-6H-pyrrolo[3,4-d]pyridazine-5-carboxylate
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PubChem ID
CID: 46879472
Canonical SMILES
CCOC(=O)c1[nH]c(C)c2cnnc(Nc3ccc(OCc4cccc(F)c4)c(Cl)c3)c12
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Compound Formula C23H20ClFN4O3
Compound Structure
Protein Name
Epidermal growth factor receptor
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase EGFR family
Uniprot ID
P00533
Gene Name
EGFR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000052 A-431 Homo sapiens (Human)  1
1
IC50 = 1210 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 > 10000 nM