Brief Information of the Compound and Protein
Compound Name
N-(3-ethynylphenyl)-6,7-dimethoxyquinolin-4-amine
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PubChem ID
CID: 25000333
SID: 56342515
Canonical SMILES
COc1cc2nccc(Nc3cccc(c3)C#C)c2cc1OC
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Compound Formula C19H16N2O2
Compound Structure
Protein Name
Epidermal growth factor receptor
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase EGFR family
Uniprot ID
P00533
Gene Name
EGFR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000052 A-431 Homo sapiens (Human)  1
1
IC50 = 42 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 19 nM