Brief Information of the Compound and Protein
Compound Name
6-N-(3-bromophenyl)-12-fluoro-8-thia-3,5-diazatricyclo[7.4.0.0^{2,7}]trideca-1(9),2(7),3,5,10,12-hexaene-6,11-diamine
    Show/Hide
PubChem ID
CID: 5328412
SID: 15800422
Canonical SMILES
Nc1cc2sc3c(Nc4cccc(Br)c4)ncnc3c2cc1F
    Show/Hide
Compound Formula C16H10BrFN4S
Compound Structure
Protein Name
Epidermal growth factor receptor
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase EGFR family
Uniprot ID
P00533
Gene Name
EGFR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000052 A-431 Homo sapiens (Human)  1
1
IC50 = 42 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 1 nM