Brief Information of the Compound and Protein
Compound Name
4-N-(3-bromophenyl)-6-N-methylquinazoline-4,6-diamine
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PubChem ID
CID: 5328203
SID: 15646582
Canonical SMILES
CNc1ccc2ncnc(Nc3cccc(Br)c3)c2c1
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Compound Formula C15H13BrN4
Compound Structure
Protein Name
Epidermal growth factor receptor
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase EGFR family
Uniprot ID
P00533
Gene Name
EGFR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000052 A-431 Homo sapiens (Human)  2
1
IC50 = 4 nM
   TI
   LI
   LO
   TS
2
IC50 = 11 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 4.074 nM
2 IC50 = 5 nM