Brief Information of the Compound and Protein
Compound Name
6-N-(3-methylphenyl)-8-thia-3,5-diazatricyclo[7.4.0.0^{2,7}]trideca-1(9),2(7),3,5,10,12-hexaene-6,12-diamine
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PubChem ID
CID: 5328407
SID: 15744659
Canonical SMILES
Cc1cccc(Nc2ncnc3c4cc(N)ccc4sc23)c1
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Compound Formula C17H14N4S
Compound Structure
Protein Name
Epidermal growth factor receptor
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase EGFR family
Uniprot ID
P00533
Gene Name
EGFR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000052 A-431 Homo sapiens (Human)  1
1
IC50 = 98 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 2.1 nM