Brief Information of the Compound and Protein
Compound Name
 Compound Info 
N-[4-(3-bromoanilino)pyrido[3,2-d]pyrimidin-6-yl]prop-2-enamide
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 PubChem ID
CID: 10523147
SID: 15549075
Canonical SMILES
Brc1cccc(Nc2ncnc3ccc(NC(=O)C=C)nc23)c1
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Compound Formula C16H12BrN5O
Compound Structure
Protein Name
 Protein Info 
Epidermal growth factor receptor
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase EGFR family
Uniprot ID
P00533
Gene Name
EGFR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000052 A-431
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 5.6 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 1.1 nM