Brief Information of the Compound and Protein
Compound Name
8-chloro-4-[(3-chloro-4-fluorophenyl)amino]-6-[(pyridin-3-ylmethyl)amino]quinoline-3-carbonitrile
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PubChem ID
CID: 17758358
SID: 29219295
Canonical SMILES
Fc1ccc(Nc2c(cnc3c(Cl)cc(NCc4cccnc4)cc23)C#N)cc1Cl
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Compound Formula C22H14Cl2FN5
Compound Structure
Protein Name
Epidermal growth factor receptor
Protein Classification
Enzyme
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Kinase
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Protein Kinase
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TK protein kinase group
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Tyrosine protein kinase EGFR family
Uniprot ID
P00533
Gene Name
EGFR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000052 A-431 Homo sapiens (Human)  1
1
IC50 > 5000 nM
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