Brief Information of the Compound and Protein
Compound Name
N-(3-chlorophenyl)-6,7-dimethoxyquinazolin-4-amine
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PubChem ID
CID: 2051
SID: 14801206
Canonical SMILES
COc1cc2ncnc(Nc3cccc(Cl)c3)c2cc1OC
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Compound Formula C16H14ClN3O2
Compound Structure
Protein Name
Epidermal growth factor receptor
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
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Tyrosine protein kinase EGFR family
Uniprot ID
P00533
Gene Name
EGFR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000052 A-431 Homo sapiens (Human)  1
1
IC50 = 0.31 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 0.3162 nM
2 IC50 = 1.6 nM
3 IC50 = 3 nM
4 IC50 = 5 nM
5 IC50 = 6 nM
6 IC50 = 120 nM