General Information of the Compound
| Compound ID |
CP0516899
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| Compound Name |
4-(6-methoxy-3,4-dihydro-2H-quinolin-1-yl)-2-methylquinazoline
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| Structure |
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| Formula |
C19H19N3O
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| Molecular Weight |
305.381
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| Canonical SMILES |
COc1ccc2N(CCCc2c1)c1nc(C)nc2ccccc12
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| InChI |
InChI=1S/C19H19N3O/c1-13-20-17-8-4-3-7-16(17)19(21-13)22-11-5-6-14-12-15(23-2)9-10-18(14)22/h3-4,7-10,12H,5-6,11H2,1-2H3
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| InChIKey |
SDVCOWGIPMODEC-UHFFFAOYSA-N
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| Physicochemical Property |
"RO5" indicates the cutoff set by lipinski's rule of five: (1) Molecular weight less than 500 Dalton; (2) xlogp less than 5; (3) No more than 5 hbonddonor (Hydrogen Bond Donor Count); (4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count); (5) No more than 10 rotbonds (Rotatable Bond Count). Show/Hide
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Map of Molecular Bioactivity Related to the Compound
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Map of Molecular Bioactivity Related to the Compound Compound Cell Line Protein Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity |
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Table of Molecular Bioactivities Related to the Compound
Protein ID: PT00922, Epidermal growth factor receptor
Protein ID: PT00844, Platelet-derived growth factor receptor beta
Protein ID: PT00864, Vascular endothelial growth factor receptor 2
Cell Viability or Cytotoxicity Assay
| Cell Line ID | Cell Line Name | Cell Line Organism | |
| CL000084 | SK-OV-3 | Homo sapiens (Human) | 1 |
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IC50 = 1.5 nM
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| CL000118 | U-251MG | Homo sapiens (Human) | 1 |
| 1 |
IC50 = 3.1 nM
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TI
LI
LO
TS
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