General Information of the Cell Line
Cell Line ID
CL000084
Cell Line Name
SK-OV-3
Synonyms
SKOV-3
SK-OV3
SK.OV.3
SKOV3
Skov3
SKO3
SKOV3 (S)
Category
Cancer cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_0532
Tissue Information
Ascites
Disease
Ovarian serous cystadenocarcinoma (NCIt: C7978)
Map of Molecular Bioactivity Related to the Cell Line
Map of Molecular Bioactivity Related to the Cell Line

Cell Line
Protein
Compound

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Cell Line
Protein ID: PT03381, 5'-nucleotidase
Compound ID Compound Name Compound Formula
CP0472500
[(2R,3S,4R,5R)-5-[6-chloro-4-(cyclopentylamino)pyrazolo[3,4-d]pyrimidin-1-yl]-3,4-dihydroxyoxolan-2-yl]methoxymethylphosphonic acid
   Show/Hide
C16H23ClN5O7P
 1
1
IC50 = 0.55 nM
   TI
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   TS
Cell Viability or Cytotoxicity Assay
Compound ID Compound Name Compound Formula
CP0003433
(Arylindolyl)maleimide deriv. 27
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C21H16N4O2  1
1
LC50 > 100000 nM
   TI
   LI
   LO
   TS
CP0003832
N'-hydroxy-N-phenyloctanediamide
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C14H20N2O3  1
1
IC50 = 2200 nM
   TI
   LI
   LO
   TS
CP0006369
6-[3-[4-[1-(5-cyanopentyl)indol-3-yl]-1-hydroxy-2,5-dioxopyrrol-3-yl]indol-1-yl]hexanenitrile
   Show/Hide
C32H31N5O3  1
1
LC50 > 100000 nM
   TI
   LI
   LO
   TS
CP0007711
(E)-3-[4-[[2-(2-methyl-1H-indol-3-yl)ethylamino]methyl]phenyl]-N'-propylprop-2-enehydrazide;2,2,2-trifluoroacetic acid
   Show/Hide
C26H31F3N4O3  2
1
GI50 = 98.3 nM
   TI
   LI
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   TS
2
LC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0015140
N-hydroxy-2-[methyl-[[3-[1-[(4-methylphenyl)methyl]piperidin-4-yl]-1,2,4-oxadiazol-5-yl]methyl]amino]pyrimidine-5-carboxamide
   Show/Hide
C22H27N7O3  1
1
IC50 = 20.5 nM
   TI
   LI
   LO
   TS
CP0016321
9-acridinamine;hydrate;hydrochloride
   Show/Hide
C13H10N2  1
1
IC50 = 5430 nM
   TI
   LI
   LO
   TS
CP0017774
4-[[7-[2,6-bis(fluoranyl)phenyl]-9-chloranyl-5H-pyrimido[5,4-d][2]benzazepin-2-yl]amino]benzoic acid
   Show/Hide
C25H15ClF2N4O2  1
1
IC50 = 530 nM
   TI
   LI
   LO
   TS
CP0024747
5-methoxy-8,8-dioxo-8lambda6-thia-4,7,15,19,24,29-hexazahexacyclo[20.5.2.12,6.19,13.117,21.025,29]dotriaconta-1(28),2(32),3,5,9,11,13(31),17(30),18,20,22,24,26-tridecaen-14-one
   Show/Hide
C26H20N6O4S  1
1
GI50 = 18.9 nM
   TI
   LI
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   TS
CP0031558
Methyl (5-(6-((4-(methylsulfonyl)piperazin-1-yl)methyl)-4-morpholinopyrrolo[2,1-f][1,2,4]triazin-2-yl)-4-(trifluoromethyl)pyridin-2-yl)carbamate
   Show/Hide
C24H29F3N8O5S  1
1
IC50 < 1000 nM
   TI
   LI
   LO
   TS
CP0034470
(-)-combretastatin
   Show/Hide
C18H20O5  1
1
IC50 = 9.7 nM
   TI
   LI
   LO
   TS
CP0057302
(2S)-2-[[4-[(2,4-diaminopyrido[3,2-d]pyrimidin-6-yl)methylamino]benzoyl]amino]pentanedioic acid
   Show/Hide
C20H21N7O5  1
1
IC50 = 10 nM
   TI
   LI
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   TS
CP0064592
[(1S,2S,3R,4S,7R,9S,10S,12R,15S)-4,12-diacetyloxy-15-[(2R,3S)-3-benzamido-2-hydroxy-3-phenylpropanoyl]oxy-1,9-dihydroxy-10,14,17,17-tetramethyl-11-oxo-6-oxatetracyclo[11.3.1.03,10.04,7]heptadec-13-en-2-yl] benzoate
   Show/Hide
C47H51NO14  1
1
IC50 = 4.4 nM
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CP0082019
(2R)-2-amino-3-[(triphenylmethyl)sulfanyl]propanoic acid
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C22H21NO2S  1
1
GI50 = 100000 nM
   TI
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CP0086475
2-[(4-methoxyphenyl)-diphenylmethyl]sulfanylethanamine
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C22H23NOS  1
1
GI50 = 80 nM
   TI
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   TS
CP0090533
N-[5-[2,3-dihydro-1,4-benzodioxine-6-carbonyl(methyl)amino]-2-methylphenyl]-2-methylquinoline-6-carboxamide
   Show/Hide
C28H25N3O4  1
1
GI50 > 1000 nM
   TI
   LI
   LO
   TS
CP0090639
N-benzyl-2-[2-[methyl(5-pyrrolidin-1-ylpentyl)amino]-3-(4-phenylphenyl)-4H-quinazolin-4-yl]acetamide
   Show/Hide
C39H45N5O  1
1
GI50 = 2760 nM
   TI
   LI
   LO
   TS
CP0112599
US8569511, 2
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C23H22F2N6O2  1
1
IC50 = 1540 nM
   TI
   LI
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   TS
CP0118656
(E)-3-(4-(4-(3-chloro-4-(3-fluorobenzyloxy)phenylamino)quinazolin-6-yl)phenyl)-N-hydroxyacrylamide
   Show/Hide
C30H22ClFN4O3  1
1
IC50 = 1200 nM
   TI
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   TS
CP0118658
5-(4-(3-chloro-4-(3-fluorobenzyloxy)phenylamino)quinazolin-6-yl)-N-hydroxyfuran-2-carboxamide
   Show/Hide
C26H18ClFN4O4  1
1
IC50 = 15000 nM
   TI
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CP0126722
N-[5-(2,3-dihydro-1,4-benzodioxine-6-carbonylamino)-2,4-dimethylphenyl]-2-methylquinoline-6-carboxamide
   Show/Hide
C28H25N3O4  1
1
GI50 > 1000 nM
   TI
   LI
   LO
   TS
CP0130031
(4-benzylphenyl)-[1-(2-fluoro-5-hydroxybenzoyl)piperidin-4-yl]methanone
   Show/Hide
C26H24FNO3  1
1
IC50 = 8000 nM
   TI
   LI
   LO
   TS
CP0130706
N-[(3S,4S)-4-(3,4-difluorophenyl)piperidin-3-yl]-2-fluoro-4-(2-methylpyrazol-3-yl)benzamide;hydrochloride
   Show/Hide
C22H22ClF3N4O  1
1
IC50 = 4710 nM
   TI
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   TS
CP0157681
N-[5-(2,3-dihydro-1,4-benzodioxine-5-carbonylamino)-2-methylphenyl]-2-(2-pyrrolidin-1-ylethoxy)quinoline-6-carboxamide
   Show/Hide
C32H32N4O5  1
1
GI50 > 1000 nM
   TI
   LI
   LO
   TS
CP0161051
N-[5-(2,3-dihydro-1,4-benzodioxine-6-carbonylamino)-2-methylphenyl]-2-(2-pyrrolidin-1-ylethoxy)quinoline-6-carboxamide
   Show/Hide
C32H32N4O5  2
1
GI50 = 1.1 nM
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2
GI50 = 2.2 nM
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CP0196973
2-[2-[4-[2-(dimethylamino)ethyl]piperazin-1-yl]-3-(4-phenylphenyl)-4H-quinazolin-4-yl]-N-[(4-methoxyphenyl)methyl]acetamide
   Show/Hide
C38H44N6O2  1
1
IC50 = 2470 nM
   TI
   LI
   LO
   TS
CP0197093
N-[5-(3,4-dihydro-1H-isochromene-7-carbonylamino)-2-methylphenyl]-2-methylquinoline-6-carboxamide
   Show/Hide
C28H25N3O3  1
1
GI50 > 1000 nM
   TI
   LI
   LO
   TS
CP0204863
(E)-N-hydroxy-3-(4-((4-methyl-3-(4-(pyridin-3-yl)pyrimidin-2-ylamino)phenylamino)methyl)phenyl)acrylamide
   Show/Hide
C26H24N6O2  1
1
IC50 = 6310 nM
   TI
   LI
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   TS
CP0229968
[1-(2,4-difluoro-5-hydroxybenzoyl)piperidin-4-yl]-(4-phenylsulfanylphenyl)methanone
   Show/Hide
C25H21F2NO3S  1
1
IC50 = 11000 nM
   TI
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   TS
CP0232442
(E)-3-(5-(4-(3-chloro-4-(3-fluorobenzyloxy)phenylamino)quinazolin-6-yl)thiophen-2-yl)-N-hydroxyacrylamide
   Show/Hide
C28H20ClFN4O3S  1
1
IC50 = 4000 nM
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CP0240165
(2R)-2-[(1-hydroxy-4-nitrosonaphthalen-2-yl)amino]-3-phenyl-N-[3-(trifluoromethyl)phenyl]propanamide
   Show/Hide
C26H20F3N3O3  1
1
IC50 = 100 nM
   TI
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   TS
CP0283354
N-(2-aminophenyl)-3-[4-[4-[3-chloro-4-[(3-fluorophenyl)methoxy]anilino]quinazolin-6-yl]phenyl]propanamide
   Show/Hide
C36H29ClFN5O2  1
1
IC50 = 13000 nM
   TI
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   TS
CP0338847
2-methoxy-6-[(E)-[(6-methoxy-2-methylquinolin-4-yl)hydrazinylidene]methyl]phenol
   Show/Hide
C19H19N3O3  1
1
IC50 = 2100 nM
   TI
   LI
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   TS
CP0345034
[(2R)-1-(4-tert-butylphenoxy)-3-(2-nitroimidazol-1-yl)propan-2-yl] 4-[(2-hydroxy-5-oxocyclopenta-1,3-dien-1-yl)methylideneamino]benzoate
   Show/Hide
C29H28N4O7  1
1
GI50 = 18000 nM
   TI
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   TS
CP0368111
N-[5-(2,3-dihydro-1,4-benzodioxin-6-ylsulfonylamino)-2-methylphenyl]-2-methylquinoline-6-carboxamide
   Show/Hide
C26H23N3O5S  1
1
GI50 > 1000 nM
   TI
   LI
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   TS
CP0370065
5-(4-chlorophenyl)-2-(4-methoxyphenyl)-[1,3]thiazolo[3,2-b][1,2,4]triazole
   Show/Hide
C17H12ClN3OS  1
1
LC50 > 50000 nM
   TI
   LI
   LO
   TS
CP0374518
CHEBI:3533
   Show/Hide
C28H38N2O4  1
1
IC50 = 385.752861 nM
   TI
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CP0378571
methyl 2-[2-[5-(dimethylamino)pentyl-methylamino]-3-(4-phenylphenyl)-4H-quinazolin-4-yl]acetate
   Show/Hide
C31H38N4O2  1
1
GI50 = 1950 nM
   TI
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CP0378573
N-benzyl-2-[2-[5-(dimethylamino)pentyl-methylamino]-3-(4-phenylphenyl)-4H-quinazolin-4-yl]acetamide
   Show/Hide
C37H43N5O  1
1
GI50 = 660 nM
   TI
   LI
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   TS
CP0383276
N-(4-methoxyphenyl)-N,2,6-trimethylfuro[2,3-d]pyrimidin-4-amine
   Show/Hide
C16H17N3O2  2
1
GI50 = 25.2 nM
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2
IC50 = 36.7 nM
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CP0390395
2-(2-(dimethylamino)-3-phenyl-3,4-dihydroquinazolin-4-yl)-N-(4-nitrobenzyl)acetamide
   Show/Hide
C25H25N5O3  1
1
GI50 > 100000 nM
   TI
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CP0394871
4-(4,6-dimorpholin-4-yl-1,3,5-triazin-2-yl)aniline
   Show/Hide
C17H22N6O2  1
1
IC50 = 8504 nM
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CP0397786
N-[[4-[(4-fluorophenyl)sulfonylamino]phenyl]methyl]-2-(3-phenyl-2-piperidin-1-yl-4H-quinazolin-4-yl)acetamide
   Show/Hide
C34H34FN5O3S  1
1
GI50 = 1950 nM
   TI
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CP0408098
(1R,4aS,10aR)-N-[(2R)-1-(3-methoxyanilino)-1-oxo-3-phenylpropan-2-yl]-6-[[(2R)-1-(3-methoxyanilino)-1-oxo-3-phenylpropan-2-yl]sulfamoyl]-1,4a-dimethyl-7-propan-2-yl-2,3,4,9,10,10a-hexahydrophenanthrene-1-carboxamide
   Show/Hide
C52H60N4O7S  1
1
IC50 = 20500 nM
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CP0408103
(1R,4aS,10aR)-N-[(2R)-1-anilino-1-oxo-3-phenylpropan-2-yl]-6-[[(2R)-1-anilino-1-oxo-3-phenylpropan-2-yl]sulfamoyl]-1,4a-dimethyl-7-propan-2-yl-2,3,4,9,10,10a-hexahydrophenanthrene-1-carboxamide
   Show/Hide
C50H56N4O5S  1
1
IC50 = 19600 nM
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CP0410268
(4bS,8R,8aR)-8-[[(2S)-1-(3-fluoroanilino)-1-oxo-3-phenylpropan-2-yl]carbamoyl]-4b,8-dimethyl-2-propan-2-yl-5,6,7,8a,9,10-hexahydrophenanthrene-3-sulfonic acid
   Show/Hide
C35H41FN2O5S  1
1
IC50 = 45700 nM
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CP0410272
(1R,4aS,10aR)-N-[(2R)-1-(3-chloro-4-fluoroanilino)-1-oxo-3-phenylpropan-2-yl]-6-[[(2R)-1-(3-chloro-4-fluoroanilino)-1-oxo-3-phenylpropan-2-yl]sulfamoyl]-1,4a-dimethyl-7-propan-2-yl-2,3,4,9,10,10a-hexahydrophenanthrene-1-carboxamide
   Show/Hide
C50H52Cl2F2N4O5S  1
1
IC50 > 50000 nM
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CP0415601
1-N,4-N-dimethyl-4-N-(5-methylfuro[2,3-d]pyrimidin-4-yl)benzene-1,4-diamine
   Show/Hide
C15H16N4O  1
1
IC50 = 95 nM
   TI
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CP0421175
methyl 2-[2-[5-[(2-methylpropan-2-yl)oxycarbonylamino]pentylimino]-3-(4-phenylphenyl)-1,4-dihydroquinazolin-4-yl]acetate
   Show/Hide
C33H40N4O4  1
1
GI50 = 4610 nM
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CP0421177
tert-butyl N-[5-[[4-[2-(benzylamino)-2-oxoethyl]-3-(4-phenylphenyl)-1,4-dihydroquinazolin-2-ylidene]amino]pentyl]carbamate
   Show/Hide
C39H45N5O3  1
1
GI50 = 1610 nM
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CP0421667
Azixa
   Show/Hide
C17H17N3O  1
1
IC50 = 2.6 nM
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CP0432230
N-(2,3-dihydro-1-benzofuran-5-yl)-N,2,6-trimethylfuro[2,3-d]pyrimidin-4-amine
   Show/Hide
C17H17N3O2  1
1
GI50 = 37.6 nM
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CP0436470
N-[5-(2,3-dihydro-1,4-benzodioxine-6-carbonylamino)-2-methylphenyl]-1,2,3,4-tetrahydroquinoline-6-carboxamide
   Show/Hide
C26H25N3O4  2
1
GI50 = 8.9 nM
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2
GI50 = 8.913 nM
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CP0438363
(1R,4aS,10aR)-1,4a-dimethyl-N-[(2R)-1-(3-methylanilino)-1-oxo-3-phenylpropan-2-yl]-6-[[(2R)-1-(3-methylanilino)-1-oxo-3-phenylpropan-2-yl]sulfamoyl]-7-propan-2-yl-2,3,4,9,10,10a-hexahydrophenanthrene-1-carboxamide
   Show/Hide
C52H60N4O5S  1
1
IC50 = 13400 nM
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CP0438459
4-[(E)-[(6-methoxy-2-methylquinolin-4-yl)hydrazinylidene]methyl]phenol
   Show/Hide
C18H17N3O2  2
1
IC50 = 2580 nM
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2
IC50 = 2750 nM
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CP0438460
4-fluoro-N'-(6-methoxy-2-methylquinolin-4-yl)benzohydrazide
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C18H16FN3O2  1
1
IC50 > 100000 nM
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CP0444435
(1R,4aS,10aR)-1,4a-dimethyl-N-[(2S)-1-(2-methylanilino)-1-oxo-3-phenylpropan-2-yl]-6-[[(2S)-1-(2-methylanilino)-1-oxo-3-phenylpropan-2-yl]sulfamoyl]-7-propan-2-yl-2,3,4,9,10,10a-hexahydrophenanthrene-1-carboxamide
   Show/Hide
C52H60N4O5S  1
1
IC50 = 10300 nM
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CP0447221
N-(4-methoxyphenyl)-2,6-dimethyl-N-propan-2-ylfuro[2,3-d]pyrimidin-4-amine
   Show/Hide
C18H21N3O2  1
1
IC50 = 7400 nM
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CP0450144
(2S)-2-[[4-[(2,4-diamino-5-prop-2-enyl-7,8-dihydro-6H-pyrido[3,2-d]pyrimidin-6-yl)methyl-prop-2-enylamino]benzoyl]amino]pentanedioic acid
   Show/Hide
C26H33N7O5  1
1
IC50 = 50240 nM
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CP0454796
5-(4,6-dimorpholin-4-yl-1,3,5-triazin-2-yl)-3-(trifluoromethyl)pyridin-2-amine
   Show/Hide
C17H20F3N7O2  1
1
IC50 = 9213 nM
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CP0458234
4-(3-fluoro-4-hydroxyphenyl)-2-[(E)-N-hydroxy-C-tridecylcarbonimidoyl]phenol
   Show/Hide
C26H36FNO3  1
1
IC50 = 26000 nM
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CP0461401
2-(2-(dimethylamino)-3-phenyl-3,4-dihydroquinazolin-4-yl)-N-(4-(4-methylphenylsulfonamido)benzyl)acetamide
   Show/Hide
C32H33N5O3S  1
1
GI50 = 15610 nM
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CP0463275
[2-(4-methylsulfonylpiperazin-1-yl)-4-morpholin-4-ylthieno[3,2-d]pyrimidin-6-yl]methanol
   Show/Hide
C16H23N5O4S2  1
1
IC50 = 23330 nM
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CP0465282
4-N-(4-methoxyphenyl)-4-N-methyl-9H-pyrimido[4,5-b]indole-2,4-diamine
   Show/Hide
C18H17N5O  2
1
GI50 = 29.9 nM
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2
IC50 = 27.6 nM
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CP0465284
4-N-(4-ethoxyphenyl)-4-N-methyl-9H-pyrimido[4,5-b]indole-2,4-diamine
   Show/Hide
C19H19N5O  1
1
IC50 = 23 nM
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CP0472963
N-(5-methoxynaphthalen-1-yl)-N,2-dimethyl-6,7-dihydro-5H-cyclopenta[d]pyrimidin-4-amine
   Show/Hide
C20H21N3O  1
1
IC50 = 1200 nM
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CP0475332
N-[3-(2,3-dihydro-1,4-benzodioxine-6-carbonylamino)-2,6-dimethylphenyl]-2-methylquinoline-6-carboxamide
   Show/Hide
C28H25N3O4  1
1
GI50 > 1000 nM
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CP0482118
N-[5-(2,3-dihydro-1,4-benzodioxine-5-carbonylamino)-2-methylphenyl]-2-methylquinoline-6-carboxamide
   Show/Hide
C27H23N3O4  1
1
GI50 > 1000 nM
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CP0485568
N-[(E)-1H-imidazol-5-ylmethylideneamino]-6-methoxy-2-methylquinolin-4-amine
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C15H15N5O  2
1
IC50 = 6730 nM
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2
IC50 = 6900 nM
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CP0485975
methyl 2-[3-(5-aminopentyl)-2-(4-phenylanilino)-4H-quinazolin-4-yl]acetate
   Show/Hide
C28H32N4O2  1
1
GI50 = 3990 nM
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CP0493586
(2S)-2-[[3-bromo-4-[(2,4-diamino-5-prop-2-enyl-7,8-dihydro-6H-pyrido[3,2-d]pyrimidin-6-yl)methylamino]benzoyl]amino]pentanedioic acid
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C23H28BrN7O5  1
1
IC50 > 100000 nM
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CP0497857
N-[(4-aminophenyl)methyl]-2-[2-(dimethylamino)-3-phenyl-4H-quinazolin-4-yl]acetamide
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C25H27N5O  1
1
GI50 > 100000 nM
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CP0504395
tert-butyl N-[5-[[4-[2-(benzylamino)-2-oxoethyl]-3-phenyl-1,4-dihydroquinazolin-2-ylidene]amino]pentyl]carbamate
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C33H41N5O3  1
1
GI50 = 7180 nM
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CP0504740
4-(6-methoxy-3,4-dihydro-2H-quinolin-1-yl)-2,6-dimethylfuro[2,3-d]pyrimidine
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C18H19N3O2  1
1
GI50 < 10 nM
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CP0508404
5-(4,6-dimorpholin-4-yl-1,3,5-triazin-2-yl)-3-methylpyridin-2-amine
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C17H23N7O2  1
1
IC50 = 6221 nM
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CP0516899
4-(6-methoxy-3,4-dihydro-2H-quinolin-1-yl)-2-methylquinazoline
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C19H19N3O  1
1
IC50 = 1.5 nM
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CP0517983
N-[4-[2-[(2S,3S,5S)-2-[[tert-butyl(dimethyl)silyl]oxymethyl]-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-3-yl]-1,3-dithian-2-yl]phenyl]-N'-hydroxyoctanediamide
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C34H52N4O7S2Si  1
1
GI50 = 12882.5 nM
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CP0519837
6-methoxy-2-methyl-N-[(E)-2-phenylethylideneamino]quinolin-4-amine
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C19H19N3O  2
1
IC50 = 40670 nM
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2
IC50 = 44670 nM
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CP0520785
(4bS,8R,8aR)-8-[[(2R)-1-anilino-1-oxo-3-phenylpropan-2-yl]carbamoyl]-4b,8-dimethyl-2-propan-2-yl-5,6,7,8a,9,10-hexahydrophenanthrene-3-sulfonic acid
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C35H42N2O5S  1
1
IC50 = 37900 nM
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CP0526577
N-ethyl-N-(4-methoxyphenyl)-2,6-dimethylfuro[2,3-d]pyrimidin-4-amine
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C17H19N3O2  1
1
IC50 = 270 nM
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CP0534755
[(1R)-1-[[(2S)-2-(3,4-dihydro-1H-isoquinoline-2-carbonylamino)-3-phenylpropanoyl]amino]-3-methylbutyl]boronic acid
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C24H32BN3O4  1
1
IC50 = 25.88 nM
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CP0538997
N-benzyl-2-[2-[4-(dimethylamino)butyl-methylamino]-3-(4-phenylphenyl)-4H-quinazolin-4-yl]acetamide
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C36H41N5O  1
1
IC50 = 9780 nM
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CP0543541
3-[6-[4-[5-(2-oxo-1,3-benzothiazol-3-yl)pentyl]piperazin-1-yl]hexyl]-1,3-benzothiazol-2-one
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C29H38N4O2S2  1
1
IC50 = 25000 nM
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CP0551819
N-(4-methoxyphenyl)-N,2-dimethyl-6,7-dihydro-5H-cyclopenta[d]pyrimidin-4-amine
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C16H20ClN3O  1
1
IC50 = 11.3 nM
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CP0552799
4-N-(5-methoxynaphthalen-2-yl)-4-N-methyl-6,7-dihydro-5H-cyclopenta[d]pyrimidine-2,4-diamine
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C19H20N4O  1
1
IC50 = 14.9 nM
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CP0553760
(2S,6R)-2,6-dimethyl-4-(4-morpholin-4-yl-6-pyridin-3-ylthieno[3,2-d]pyrimidin-2-yl)morpholine
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C21H25N5O2S  1
1
IC50 = 15680 nM
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CP0563000
5-(4,6-dimorpholin-4-yl-1,3,5-triazin-2-yl)pyrimidin-2-amine
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C15H20N8O2  1
1
IC50 = 270 nM
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CP0563579
4-[(E)-[(6-methoxy-2-methylquinolin-4-yl)hydrazinylidene]methyl]benzoic acid
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C19H17N3O3  1
1
IC50 = 70000 nM
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CP0570311
(2R,6S)-2,6-dimethyl-4-[4-morpholin-4-yl-6-(1H-pyrazol-4-yl)thieno[3,2-d]pyrimidin-2-yl]morpholine
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C19H24N6O2S  1
1
IC50 = 10120 nM
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CP0574318
5-(4,6-dimorpholin-4-yl-1,3,5-triazin-2-yl)pyrazin-2-amine
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C15H20N8O2  1
1
IC50 = 4428 nM
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CP0858674
N-(4-Methoxyphenyl)-N,2,6-trimethylfuro[2,3-d]pyrimidin-4-amine hydrochloride
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C16H18ClN3O2  2
1
IC50 = 50.4 nM
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2
IC50 = 62.1 nM
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CP0859455
N2-(2-aminophenyl)-N5-(4-(3-ethynylphenylamino)quinazolin-7-yl)pyridine-2,5-dicarboxamide
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C29H21N7O2  1
1
IC50 > 50000 nM
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CP0863011
N,N,N-trimethyl-3-(octadec-1-en-2-ylsulfonyl)propan-1-aminium chloride
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C24H50ClNO2S  1
1
IC50 = 6740 nM
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CP0867448
5-Ethyl-3-(morpholinomethyl)-6-thioxo-5,6,8,9,10,10ahexahydropyrimido[5,4-e]pyrrolo[1,2-c]pyrimidin-1(2H)-one
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C16H23N5O2S  1
1
IC50 = 4670 nM
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CP0869038
5-Phenyl-3-(1'-morpholinoethyl)-6-thioxo-5,6,8,9,10,10ahexahydropyrimido[5,4-e]pyrrolo[1,2-c]pyrimidin-1(2H)-one
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C21H25N5O2S  1
1
IC50 = 1340 nM
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CP0869039
3-(3-Hydroxyphenyl)-5-ethyl-1-morpholino-6-thioxo-5,6,8,9,10,10a-hexahydropyrido[3,2-e]pyrrolo[1,2-c]pyrimidine-2-carbonitrile
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C23H25N5O2S  1
1
IC50 = 14560 nM
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CP0873710
1-Morpholino-3-(1'-morpholinoethyl)-5-phenyl-8,9,10,10ahexahydropyrimido[5,4-e]pyrrolo[1,2-c]pyrimidine-6(5H)-thione
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C25H32N6O2S  1
1
IC50 = 78450 nM
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CP0873711
1-Morpholino-3-(morpholinomethyl)-5-phenyl-8,9,10,10ahexahydropyrimido[5,4-e]pyrrolo[1,2-c]pyrimidine-6(5H)-thione
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C24H30N6O2S  1
1
IC50 = 74530 nM
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CP0881577
3-(3-Methoxyphenyl)-1-morpholino-5-phenyl-8,9,10,10atetrahydropyrimido[5,4-e]pyrrolo[1,2-c]pyrimidine-6(5H)-thione
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C26H27N5O2S  1
1
IC50 = 60460 nM
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CP0891722
5-Ethyl-3-(10-morpholinoethyl)-6-thioxo-5,6,8,9,10,10ahexahydropyrimido[5,4-e]pyrrolo[1,2-c]pyrimidin-1(2H)-one
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C17H25N5O2S  1
1
IC50 = 1670 nM
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CP0897293
1-(7-Benzyl-2-methyl-5H-pyrrolo[3,2-d]pyrimidin-4-yl)-6-methoxy-1,2,3,4-tetrahydroquinoline hydrochloride
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C24H25ClN4O  1
1
GI50 = 423 nM
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CP0906523
7-Benzyl-N-(4-methoxyphenyl)-N,2,5-trimethyl-5H-pyrrolo[3,2-d]pyrimidin-4-amine hydrochloride
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C23H25ClN4O  1
1
GI50 = 45.4 nM
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CP0968870
(R)-3-(4-(6-chloro-5-(pyrrolidin-3-ylamino)-1H-indazol-3-yl)-1H-pyrazol-1-yl)benzonitrile
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C21H18ClN7  1
1
GI50 = 496 nM
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Protein family and CMB statistics Related to the Cell Line
Cell Lines Derived from the same Tissue Source (Ascites)
Cell Line Name Organism Disease
PEO1 Homo sapiens (Human) BRCA2-associated hereditary breast and ovarian cancer syndrome
MAST Homo sapiens (Human) Breast carcinoma
Ramos Homo sapiens (Human) Burkitt lymphoma
CA46 Homo sapiens (Human) Burkitt lymphoma
CellSensor STAT6-bla RA-1 Homo sapiens (Human) Burkitt lymphoma
NCI-H716 Homo sapiens (Human) Cecum adenocarcinoma
COLO 205 Homo sapiens (Human) Colon adenocarcinoma
COLO 201 Homo sapiens (Human) Colon adenocarcinoma
DiFi Homo sapiens (Human) Colorectal carcinoma
U-2932 Homo sapiens (Human) Diffuse large B-cell lymphoma activated B-cell type
DB Homo sapiens (Human) Diffuse large B-cell lymphoma germinal center B-cell type
HEC-50B Homo sapiens (Human) Endometrial adenocarcinoma
SNU-5 Homo sapiens (Human) Gastric adenocarcinoma
SNU-16 Homo sapiens (Human) Gastric adenocarcinoma
SNU-620 Homo sapiens (Human) Gastric adenocarcinoma
SNU-638 Homo sapiens (Human) Gastric adenocarcinoma
SNU-668 Homo sapiens (Human) Gastric signet ring cell adenocarcinoma
OVCAR-3 Homo sapiens (Human) High grade ovarian serous adenocarcinoma
OVCAR-5 Homo sapiens (Human) High grade ovarian serous adenocarcinoma
COV318 Homo sapiens (Human) High grade ovarian serous adenocarcinoma
ZR-75-1 Homo sapiens (Human) Invasive breast carcinoma of no special type
SK-HEP-1 Homo sapiens (Human) Liver and intrahepatic bile duct epithelial neoplasm
OV-90 Homo sapiens (Human) Ovarian adenocarcinoma
LK2 Homo sapiens (Human) Ovarian carcinoma
RMG-I Homo sapiens (Human) Ovarian clear cell adenocarcinoma
PA-1 Homo sapiens (Human) Ovarian mixed germ cell tumor
SKOV3/TR Homo sapiens (Human) Ovarian serous cystadenocarcinoma
AsPC-1 Homo sapiens (Human) Pancreatic ductal adenocarcinoma
HEC Homo sapiens (Human) Peritoneal malignant mesothelioma
Ehrlich-Lettre ascites strain E Mus musculus (Mouse) Malignant neoplasms of the mouse mammary gland
RAW 264.7 Mus musculus (Mouse) Mouse leukemia
L1210 Mus musculus (Mouse) Mouse leukemia
L1210/R81 Mus musculus (Mouse) Mouse leukemia
RAW-Lucia ISG Mus musculus (Mouse) Mouse leukemia
RAW-Lucia ISG-KO-STING Mus musculus (Mouse) Mouse leukemia
RAW 264 Mus musculus (Mouse) Mouse leukemia
J774 Mus musculus (Mouse) Mouse reticulum cell sarcoma
J774A1 Mus musculus (Mouse) Mouse reticulum cell sarcoma
HTC Rattus norvegicus (Rat) Rat hepatocellular carcinoma