Compound ID |
Compound Name |
Compound Formula |
CP0041166
|
5-{[(5Z)-4-[(1-benzyl-1H-indol-5-yl)amino]-6-oxo-5H,6H,7H-pyrrolo[2,3-d]pyrimidin-5-ylidene]methyl}-4-methyl-N-[2-(morpholin-4-yl)ethyl]-1H-pyrrole-2-carboxamide
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|
C34H34N8O3
|
1
|
1 |
IC50 = 40 nM
|
|
|
CP0201108
|
5-{[(5Z)-4-[(3-ethynylphenyl)amino]-6-oxo-5H,6H,7H-pyrrolo[2,3-d]pyrimidin-5-ylidene]methyl}-4-methyl-N-[2-(morpholin-4-yl)ethyl]-1H-pyrrole-2-carboxamide
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|
C27H27N7O3
|
1
|
1 |
IC50 = 40 nM
|
|
|
CP0062561
|
(5Z)-4-[(1-benzyl-1H-indazol-5-yl)amino]-5-{[3-methyl-5-(morpholin-4-ylcarbonyl)-1H-pyrrol-2-yl]methylidene}-5H,6H,7H-pyrrolo[2,3-d]pyrimidin-6-one
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|
C31H28N8O3
|
1
|
1 |
IC50 = 100 nM
|
|
|
CP0063852
|
(5Z)-4-[(3-chloro-4-fluorophenyl)amino]-5-({5-[(4-ethylpiperazin-1-yl)carbonyl]-3-methyl-1H-pyrrol-2-yl}methylidene)-5H,6H,7H-pyrrolo[2,3-d]pyrimidin-6-one
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|
C25H25ClFN7O2
|
1
|
1 |
IC50 = 100 nM
|
|
|
CP0088175
|
5-{[(5Z)-4-[(3-chloro-4-fluorophenyl)amino]-6-oxo-5H,6H,7H-pyrrolo[2,3-d]pyrimidin-5-ylidene]methyl}-4-methyl-N-[2-(morpholin-4-yl)ethyl]-1H-pyrrole-2-carboxamide
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|
C25H25ClFN7O3
|
1
|
1 |
IC50 = 100 nM
|
|
|
CP0206231
|
(5Z)-4-[(1-benzyl-1H-indol-5-yl)amino]-5-{[3-methyl-5-(morpholin-4-ylcarbonyl)-1H-pyrrol-2-yl]methylidene}-5H,6H,7H-pyrrolo[2,3-d]pyrimidin-6-one
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|
C32H29N7O3
|
1
|
1 |
IC50 = 100 nM
|
|
|
CP0217755
|
(5Z)-4-[(3-chloro-4-fluorophenyl)amino]-5-({3-methyl-5-[(4-methylpiperazin-1-yl)carbonyl]-1H-pyrrol-2-yl}methylidene)-5H,6H,7H-pyrrolo[2,3-d]pyrimidin-6-one
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|
C24H23ClFN7O2
|
1
|
1 |
IC50 = 200 nM
|
|
|
CP0357546
|
5-{[(5Z)-4-[(3-chloro-4-fluorophenyl)amino]-6-oxo-5H,6H,7H-pyrrolo[2,3-d]pyrimidin-5-ylidene]methyl}-N-[2-(diethylamino)ethyl]-4-methyl-1H-pyrrole-2-carboxamide
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|
C25H27ClFN7O2
|
1
|
1 |
IC50 = 200 nM
|
|
|
CP0217745
|
(5Z)-4-[(3-chloro-4-fluorophenyl)amino]-5-[(3,5-dimethyl-1H-pyrrol-2-yl)methylidene]-5H,6H,7H-pyrrolo[2,3-d]pyrimidin-6-one
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|
C19H15ClFN5O
|
1
|
1 |
IC50 = 300 nM
|
|
|
CP0084269
|
(5Z)-4-[(3-chloro-4-fluorophenyl)amino]-5-{[3-methyl-5-(morpholin-4-ylcarbonyl)-1H-pyrrol-2-yl]methylidene}-5H,6H,7H-pyrrolo[2,3-d]pyrimidin-6-one
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|
C23H20ClFN6O3
|
1
|
1 |
IC50 = 400 nM
|
|
|
CP0204735
|
(5Z)-4-[(3-chloro-4-fluorophenyl)amino]-5-({5-[(3,5-dimethylpiperazin-1-yl)carbonyl]-3-methyl-1H-pyrrol-2-yl}methylidene)-5H,6H,7H-pyrrolo[2,3-d]pyrimidin-6-one
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|
C25H25ClFN7O2
|
1
|
1 |
IC50 = 500 nM
|
|
|
CP0255898
|
(5Z)-4-(2,3-dihydro-1H-inden-5-ylamino)-5-{[3-methyl-5-(morpholin-4-ylcarbonyl)-1H-pyrrol-2-yl]methylidene}-5H,6H,7H-pyrrolo[2,3-d]pyrimidin-6-one
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|
C26H26N6O3
|
1
|
1 |
IC50 > 5000 nM
|
|
|
CP0358290
|
5-{[(5Z)-4-[(3-chloro-4-fluorophenyl)amino]-6-oxo-5H,6H,7H-pyrrolo[2,3-d]pyrimidin-5-ylidene]methyl}-4-methyl-1H-pyrrole-2-carboxylic acid
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|
C19H13ClFN5O3
|
1
|
1 |
IC50 > 5000 nM
|
|
|