General Information of the Cell Line
Cell Line ID
CL000584
Cell Line Name
RAW-Lucia ISG
Category
Cancer cell line
Organism
Mus musculus (Mouse)
Cellosaurus ID
CVCL_X596
Tissue Information
Ascites
Disease
Mouse leukemia (NCIt: C21604)
Map of Molecular Bioactivity Related to the Cell Line
Map of Molecular Bioactivity Related to the Cell Line

Cell Line
Protein
Compound

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Cell Line
Protein ID: PT04739, Cyclic GMP-AMP synthase
 Protein Info 
Compound ID Compound Name Compound Formula
CP0953224
 Compound Info 
3-(1-(6,7-dichloro-1H-benzo[d]imidazol-2-yl)-5-hydroxy-3-methyl-1H-pyrazol-4-yl)isobenzofuran-1(3H)-one
   Show/Hide
C19H12Cl2N4O3
  1
1
IC50 = 2120 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0579667
 Compound Info 
1,1,1,3,3,3-hexafluoropropan-2-yl 6,7-dichloro-9-(1-methylpyrazol-3-yl)-1,3,4,5-tetrahydropyrido[4,3-b]indole-2-carboxylate
   Show/Hide
C19H14Cl2F6N4O2
  1
1
IC50 = 3230 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0564583
 Compound Info 
N-[2-[6,7-dichloro-9-(1-methylpyrazol-3-yl)-1,3,4,5-tetrahydropyrido[4,3-b]indol-2-yl]-2-oxoethyl]-2,2-difluoro-2-(4-methylphenoxy)acetamide
   Show/Hide
C26H23Cl2F2N5O3
  1
1
IC50 = 6690 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0564586
 Compound Info 
N-[2-[6,7-dichloro-9-(1-methylpyrazol-3-yl)-1,3,4,5-tetrahydropyrido[4,3-b]indol-2-yl]-2-oxoethyl]-3-[5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl]benzamide
   Show/Hide
C27H20Cl2F3N7O3
  1
1
IC50 = 7620 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0555277
 Compound Info 
N-[2-[6,7-dichloro-9-(1-methylpyrazol-3-yl)-1,3,4,5-tetrahydropyrido[4,3-b]indol-2-yl]-2-oxoethyl]-2-(furan-2-yl)acetamide
   Show/Hide
C23H21Cl2N5O3
  1
1
IC50 = 7700 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0527945
 Compound Info 
[2-[9b-[3,5-bis(trifluoromethyl)anilino]-6,7-dichloro-3,4-dihydro-1H-pyrido[4,3-b]indol-2-yl]-2-oxoethyl] acetate
   Show/Hide
C23H17Cl2F6N3O3
  1
1
IC50 = 7940 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0947460
 Compound Info 
1-(6,7-Dichloro-9b-(1H-indol-3-yl)-1,3,4,4a,5,9b-hexahydro-2H-pyrido[4,3-b]indol-2-yl)-2-hydroxyethan-1-one
   Show/Hide
C21H19Cl2N3O2
  1
1
IC50 = 8420 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0955082
 Compound Info 
2-(6,7-Dichloro-9b-(1H-indol-3-yl)-1,3,4,4a,5,9b-hexahydro-2H-pyrido[4,3-b]indol-2-yl)-2-oxoethyl Acetate
   Show/Hide
C23H21Cl2N3O3
  1
1
IC50 = 8750 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0545588
 Compound Info 
[2-[6,7-dichloro-9b-[2-formyl-4-(trifluoromethyl)anilino]-3,4-dihydro-1H-pyrido[4,3-b]indol-2-yl]-2-oxoethyl] acetate
   Show/Hide
C23H18Cl2F3N3O4
  1
1
IC50 = 9010 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0573341
 Compound Info 
N-[2-[6,7-dichloro-9-(1-methylpyrazol-3-yl)-1,3,4,5-tetrahydropyrido[4,3-b]indol-2-yl]-2-oxoethyl]-2-(5-methyl-1,2-oxazol-3-yl)acetamide
   Show/Hide
C23H22Cl2N6O3
  1
1
IC50 = 9200 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0527948
 Compound Info 
1-[9b-[3,5-bis(trifluoromethyl)anilino]-6,7-dichloro-3,4-dihydro-1H-pyrido[4,3-b]indol-2-yl]-2-hydroxyethanone
   Show/Hide
C21H15Cl2F6N3O2
  1
1
IC50 = 9560 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0967557
 Compound Info 
2-(6,7-Dichloro-9b-(1H-indol-3-yl)-1,3,4,9b-tetrahydro-2H-pyrido[4,3-b]indol-2-yl)-2-oxoethyl Acetate
   Show/Hide
C23H19Cl2N3O3
  1
1
IC50 = 9730 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0549330
 Compound Info 
1-[6,7-dichloro-9b-[4-(trifluoromethyl)anilino]-3,4-dihydro-1H-pyrido[4,3-b]indol-2-yl]-2-hydroxyethanone
   Show/Hide
C20H16Cl2F3N3O2
  1
1
IC50 = 9940 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0564585
 Compound Info 
2-amino-1-[6,7-dichloro-9-(1-methylpyrazol-3-yl)-1,3,4,5-tetrahydropyrido[4,3-b]indol-2-yl]ethanone
   Show/Hide
C17H17Cl2N5O
  1
1
IC50 = 10900 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0573339
 Compound Info 
[2-[6,7-dichloro-9b-(3-chloro-2-formylanilino)-3,4-dihydro-1H-pyrido[4,3-b]indol-2-yl]-2-oxoethyl] acetate
   Show/Hide
C22H18Cl3N3O4
  1
1
IC50 = 11100 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0527944
 Compound Info 
2-amino-N-[2-[6,7-dichloro-9-(1-methylpyrazol-3-yl)-1,3,4,5-tetrahydropyrido[4,3-b]indol-2-yl]-2-oxoethyl]acetamide
   Show/Hide
C19H20Cl2N6O2
  1
1
IC50 = 11400 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0957294
 Compound Info 
1-(6,7-Dichloro-9b-(1H-indol-3-yl)-1,3,4,9b-tetrahydro-2H-pyrido[4,3-b]indol-2-yl)-2-hydroxyethan-1-one
   Show/Hide
C21H17Cl2N3O2
  1
1
IC50 = 14200 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0549328
 Compound Info 
[2-[6,7-dichloro-9b-(4-chloro-2-formylanilino)-3,4-dihydro-1H-pyrido[4,3-b]indol-2-yl]-2-oxoethyl] acetate
   Show/Hide
C22H18Cl3N3O4
  1
1
IC50 = 16300 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0941170
 Compound Info 
(R)-N-(2-(6,7-Dichloro-9-(1-methyl-1H-pyrazol-3-yl)-1,3,4,5-tetrahydro-2H-pyrido[4,3-b]indol-2 yl)-2-oxoethyl)-4,4-difluoropyrrolidine-2-carboxamide
   Show/Hide
C22H22Cl2F2N6O2
  1
1
IC50 = 17400 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0547099
 Compound Info 
1-[6,7-dichloro-9-(1-methylpyrazol-3-yl)-1,3,4,5-tetrahydropyrido[4,3-b]indol-2-yl]-2-hydroxyethanone
   Show/Hide
C17H16Cl2N4O2
  1
1
IC50 = 20000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0577822
 Compound Info 
1-(5,6-dichloro-11,14-dimethoxy-8,16,18-triazapentacyclo[7.7.4.01,9.02,7.010,15]icosa-2(7),3,5,10,12,14-hexaen-18-yl)-2-hydroxyethanone
   Show/Hide
C21H21Cl2N3O4
  1
1
IC50 = 20100 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0549843
 Compound Info 
1-[6,7-dichloro-9-(1-methylpyrazol-3-yl)-1,3,4,5-tetrahydropyrido[4,3-b]indol-2-yl]-2-(methylamino)ethanone
   Show/Hide
C18H19Cl2N5O
  1
1
IC50 = 21900 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0954216
 Compound Info 
1-(6,7-Dichloro-9b-(6-chloro-1H-indol-3-yl)-1,3,4,9b-tetrahydro-2H-pyrido[4,3 b]indol-2-yl)-2-hydroxyethan-1-one
   Show/Hide
C21H16Cl3N3O2
  1
1
IC50 = 22000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0564584
 Compound Info 
1-[6,7-dichloro-9b-(2-methoxyanilino)-3,4-dihydro-1H-pyrido[4,3-b]indol-2-yl]-2-hydroxyethanone
   Show/Hide
C20H19Cl2N3O3
  1
1
IC50 = 22800 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0527947
 Compound Info 
2-hydroxy-1-[(1R,9S,13R,14R)-5,6,17-trichloro-22-oxa-8,11,21-triazahexacyclo[12.7.1.01,9.02,7.09,13.015,20]docosa-2(7),3,5,15(20),16,18-hexaen-11-yl]ethanone
   Show/Hide
C20H16Cl3N3O3
  1
1
IC50 = 37600 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
Protein ID: PT05006, Stimulator of interferon genes protein
 Protein Info 
Protein family and CMB statistics Related to the Cell Line
Cell Lines Derived from the same Tissue Source (Ascites)
Cell Line Name Organism Disease
PEO1
 Cell Line Info 
Homo sapiens (Human) BRCA2-associated hereditary breast and ovarian cancer syndrome
MAST
 Cell Line Info 
Homo sapiens (Human) Breast carcinoma
Ramos
 Cell Line Info 
Homo sapiens (Human) Burkitt lymphoma
CA46
 Cell Line Info 
Homo sapiens (Human) Burkitt lymphoma
CellSensor STAT6-bla RA-1
 Cell Line Info 
Homo sapiens (Human) Burkitt lymphoma
NCI-H716
 Cell Line Info 
Homo sapiens (Human) Cecum adenocarcinoma
COLO 205
 Cell Line Info 
Homo sapiens (Human) Colon adenocarcinoma
COLO 201
 Cell Line Info 
Homo sapiens (Human) Colon adenocarcinoma
DiFi
 Cell Line Info 
Homo sapiens (Human) Colorectal carcinoma
U-2932
 Cell Line Info 
Homo sapiens (Human) Diffuse large B-cell lymphoma activated B-cell type
DB
 Cell Line Info 
Homo sapiens (Human) Diffuse large B-cell lymphoma germinal center B-cell type
HEC-50B
 Cell Line Info 
Homo sapiens (Human) Endometrial adenocarcinoma
SNU-5
 Cell Line Info 
Homo sapiens (Human) Gastric adenocarcinoma
SNU-16
 Cell Line Info 
Homo sapiens (Human) Gastric adenocarcinoma
SNU-620
 Cell Line Info 
Homo sapiens (Human) Gastric adenocarcinoma
SNU-638
 Cell Line Info 
Homo sapiens (Human) Gastric adenocarcinoma
SNU-668
 Cell Line Info 
Homo sapiens (Human) Gastric signet ring cell adenocarcinoma
OVCAR-3
 Cell Line Info 
Homo sapiens (Human) High grade ovarian serous adenocarcinoma
OVCAR-5
 Cell Line Info 
Homo sapiens (Human) High grade ovarian serous adenocarcinoma
COV318
 Cell Line Info 
Homo sapiens (Human) High grade ovarian serous adenocarcinoma
ZR-75-1
 Cell Line Info 
Homo sapiens (Human) Invasive breast carcinoma of no special type
SK-HEP-1
 Cell Line Info 
Homo sapiens (Human) Liver and intrahepatic bile duct epithelial neoplasm
OV-90
 Cell Line Info 
Homo sapiens (Human) Ovarian adenocarcinoma
LK2
 Cell Line Info 
Homo sapiens (Human) Ovarian carcinoma
RMG-I
 Cell Line Info 
Homo sapiens (Human) Ovarian clear cell adenocarcinoma
PA-1
 Cell Line Info 
Homo sapiens (Human) Ovarian mixed germ cell tumor
SK-OV-3
 Cell Line Info 
Homo sapiens (Human) Ovarian serous cystadenocarcinoma
SKOV3/TR
 Cell Line Info 
Homo sapiens (Human) Ovarian serous cystadenocarcinoma
AsPC-1
 Cell Line Info 
Homo sapiens (Human) Pancreatic ductal adenocarcinoma
HEC
 Cell Line Info 
Homo sapiens (Human) Peritoneal malignant mesothelioma
Ehrlich-Lettre ascites strain E
 Cell Line Info 
Mus musculus (Mouse) Malignant neoplasms of the mouse mammary gland
RAW 264.7
 Cell Line Info 
Mus musculus (Mouse) Mouse leukemia
L1210
 Cell Line Info 
Mus musculus (Mouse) Mouse leukemia
L1210/R81
 Cell Line Info 
Mus musculus (Mouse) Mouse leukemia
RAW-Lucia ISG-KO-STING
 Cell Line Info 
Mus musculus (Mouse) Mouse leukemia
RAW 264
 Cell Line Info 
Mus musculus (Mouse) Mouse leukemia
J774
 Cell Line Info 
Mus musculus (Mouse) Mouse reticulum cell sarcoma
J774A1
 Cell Line Info 
Mus musculus (Mouse) Mouse reticulum cell sarcoma
HTC
 Cell Line Info 
Rattus norvegicus (Rat) Rat hepatocellular carcinoma