Brief Information of the Compound and Protein
Compound Name
 Compound Info 
3-(1-(6,7-dichloro-1H-benzo[d]imidazol-2-yl)-5-hydroxy-3-methyl-1H-pyrazol-4-yl)isobenzofuran-1(3H)-one
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Canonical SMILES
Cc1nn(-c2nc3ccc(Cl)c(Cl)c3[nH]2)c(O)c1C1OC(=O)c2ccccc21
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Compound Formula C19H12Cl2N4O3
Compound Structure
Protein Name
 Protein Info 
Cyclic GMP-AMP synthase
Protein Classification
Enzyme
>
Transferase
Uniprot ID
Q8C6L5
Gene Name
CGAS
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000584 RAW-Lucia ISG
 Cell Line Info 
Mus musculus (Mouse)  1
1
IC50 = 2120 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 110 nM
2 Kd = 36 nM