General Information of the Cell Line
Cell Line ID
CL000274
Cell Line Name
SK-HEP-1
Synonyms
SK-Hep-1
SK HEP-1
SK HEP 01
SK-Hep1
Sk-Hep1
SK Hep1
SKHEP-1
SKHEP1
SKHep1
SK_HEP1
Category
Cancer cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_0525
Tissue Information
Ascites
Disease
Liver and intrahepatic bile duct epithelial neoplasm (NCIt: C7106)
Map of Molecular Bioactivity Related to the Cell Line
Map of Molecular Bioactivity Related to the Cell Line

Cell Line
Protein
Compound

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Cell Line
Protein ID: PT02791, Hypoxia-inducible factor 1-alpha
 Protein Info 
Compound ID Compound Name Compound Formula
CP0393031
 Compound Info 
2-[2-(4-adamantan-1-yl-phenoxy)-acetylamino]-isonicotinamide
   Show/Hide
C24H27N3O3
  1
1
IC50 = 600 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0442349
 Compound Info 
2-[2-(4-adamantan-1-yl-phenoxy)-acetylamino]-N-(3-imidazol-1-yl-propyl)-isonicotinamide
   Show/Hide
C30H35N5O3
  1
1
IC50 = 900 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0454169
 Compound Info 
2-[2-(4-adamantan-1-yl-phenoxy)-acetylamino]-isonicotinic acid methyl ester
   Show/Hide
C25H28N2O4
  1
1
IC50 = 1030 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0440841
 Compound Info 
5-[2-(4-adamantan-1-yl-phenoxy)-acetylamino]-N-(3-imidazol-1-yl-propyl)-nicotinamide
   Show/Hide
C30H35N5O3
  1
1
IC50 = 1900 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0490586
 Compound Info 
2-[2-(4-adamantan-1-yl-phenoxy)-acetylamino]-isonicotinic acid
   Show/Hide
C24H26N2O4
  1
1
IC50 = 2000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0399590
 Compound Info 
2-[2-(4-adamantan-1-yl-phenoxy)-acetylamino]-N-(4-chloro-phenyl)-isonicotinamide
   Show/Hide
C30H30ClN3O3
  1
1
IC50 = 2500 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0434361
 Compound Info 
2-[2-(4-adamantan-1-yl-phenoxy)-acetylamino]-N-(2-pyridin-4-yl-ethyl)-isonicotinamide
   Show/Hide
C31H34N4O3
  1
1
IC50 = 3400 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0454275
 Compound Info 
5-[2-(4-adamantan-1-yl-phenoxy)-acetylamino]-N-furan-2-ylmethyl-nicotinamide
   Show/Hide
C29H31N3O4
  1
1
IC50 = 4100 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0449106
 Compound Info 
5-[2-(4-adamantan-1-yl-phenoxy)-acetylamino]-nicotinamide
   Show/Hide
C24H27N3O3
  1
1
IC50 = 11900 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0016093
 Compound Info 
(5-(1-benzyl-1H-indazol-3-yl)furan-2-yl)methanol
   Show/Hide
C19H16N2O2
  1
1
IC50 > 30000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0454170
 Compound Info 
5-[2-(4-adamantan-1-yl-phenoxy)-acetylamino]-nicotinic acid
   Show/Hide
C24H26N2O4
  1
1
IC50 > 30000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0454171
 Compound Info 
5-[2-(4-adamantan-1-yl-phenoxy)-acetylamino]-nicotinic acid methyl ester
   Show/Hide
C25H28N2O4
  1
1
IC50 > 30000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0457924
 Compound Info 
5-[2-(4-adamantan-1-yl-phenoxy)-acetylamino]-N-(2-pyridin-4-yl-ethyl)-nicotinamide
   Show/Hide
C31H34N4O3
  1
1
IC50 > 30000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0464172
 Compound Info 
2-[2-(4-adamantan-1-yl-phenoxy)-acetylamino]-N-furan-2-ylmethyl-isonicotinamide
   Show/Hide
C29H31N3O4
  1
1
IC50 > 30000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
Protein ID: PT06146, Solute carrier family 12 member 5
 Protein Info 
Cell Viability or Cytotoxicity Assay
Compound ID Compound Name Compound Formula
CP0001157
 Compound Info 
N-[5-[4-[2-(dimethylamino)ethylamino]quinazolin-6-yl]-2-methoxypyridin-3-yl]butane-1-sulfonamide
   Show/Hide
 C22H30N6O3S  1
1
IC50 = 280 nM
   TI
   LI
   LO
   TS
CP0013085
 Compound Info 
N-hydroxy-7-[2-[3-(hydroxymethyl)phenyl]-6-morpholin-4-ylpurin-9-yl]heptanamide
   Show/Hide
 C23H30N6O4  1
1
IC50 = 790 nM
   TI
   LI
   LO
   TS
CP0396392
 Compound Info 
1-[2-[4-[1-adamantyl(phenyl)methyl]phenyl]ethyl]-4-methylpiperazine
   Show/Hide
 C30H40N2  1
1
LC50 = 9.02 nM
   TI
   LI
   LO
   TS
CP0408582
 Compound Info 
1-[3-[4-[1-adamantyl(phenyl)methyl]phenyl]propyl]piperazine
   Show/Hide
 C30H40N2  1
1
LC50 = 8.7 nM
   TI
   LI
   LO
   TS
CP0452777
 Compound Info 
1-[3-[4-[1-adamantyl(phenyl)methyl]phenyl]propyl]-4-methylpiperazine
   Show/Hide
 C31H42N2  1
1
LC50 = 9.24 nM
   TI
   LI
   LO
   TS
CP0475008
 Compound Info 
N-[(3,4-dimethoxyphenyl)methyl]-4-[(4S)-4-(2-methylpropyl)-2,5-dioxoimidazolidin-1-yl]benzenesulfonamide
   Show/Hide
 C22H27N3O6S  1
1
IC50 = 2440 nM
   TI
   LI
   LO
   TS
Protein family and CMB statistics Related to the Cell Line
Cell Lines Derived from the same Tissue Source (Ascites)
Cell Line Name Organism Disease
PEO1
 Cell Line Info 
Homo sapiens (Human) BRCA2-associated hereditary breast and ovarian cancer syndrome
MAST
 Cell Line Info 
Homo sapiens (Human) Breast carcinoma
Ramos
 Cell Line Info 
Homo sapiens (Human) Burkitt lymphoma
CA46
 Cell Line Info 
Homo sapiens (Human) Burkitt lymphoma
CellSensor STAT6-bla RA-1
 Cell Line Info 
Homo sapiens (Human) Burkitt lymphoma
NCI-H716
 Cell Line Info 
Homo sapiens (Human) Cecum adenocarcinoma
COLO 205
 Cell Line Info 
Homo sapiens (Human) Colon adenocarcinoma
COLO 201
 Cell Line Info 
Homo sapiens (Human) Colon adenocarcinoma
DiFi
 Cell Line Info 
Homo sapiens (Human) Colorectal carcinoma
U-2932
 Cell Line Info 
Homo sapiens (Human) Diffuse large B-cell lymphoma activated B-cell type
DB
 Cell Line Info 
Homo sapiens (Human) Diffuse large B-cell lymphoma germinal center B-cell type
HEC-50B
 Cell Line Info 
Homo sapiens (Human) Endometrial adenocarcinoma
SNU-5
 Cell Line Info 
Homo sapiens (Human) Gastric adenocarcinoma
SNU-16
 Cell Line Info 
Homo sapiens (Human) Gastric adenocarcinoma
SNU-620
 Cell Line Info 
Homo sapiens (Human) Gastric adenocarcinoma
SNU-638
 Cell Line Info 
Homo sapiens (Human) Gastric adenocarcinoma
SNU-668
 Cell Line Info 
Homo sapiens (Human) Gastric signet ring cell adenocarcinoma
OVCAR-3
 Cell Line Info 
Homo sapiens (Human) High grade ovarian serous adenocarcinoma
OVCAR-5
 Cell Line Info 
Homo sapiens (Human) High grade ovarian serous adenocarcinoma
COV318
 Cell Line Info 
Homo sapiens (Human) High grade ovarian serous adenocarcinoma
ZR-75-1
 Cell Line Info 
Homo sapiens (Human) Invasive breast carcinoma of no special type
OV-90
 Cell Line Info 
Homo sapiens (Human) Ovarian adenocarcinoma
LK2
 Cell Line Info 
Homo sapiens (Human) Ovarian carcinoma
RMG-I
 Cell Line Info 
Homo sapiens (Human) Ovarian clear cell adenocarcinoma
PA-1
 Cell Line Info 
Homo sapiens (Human) Ovarian mixed germ cell tumor
SK-OV-3
 Cell Line Info 
Homo sapiens (Human) Ovarian serous cystadenocarcinoma
SKOV3/TR
 Cell Line Info 
Homo sapiens (Human) Ovarian serous cystadenocarcinoma
AsPC-1
 Cell Line Info 
Homo sapiens (Human) Pancreatic ductal adenocarcinoma
HEC
 Cell Line Info 
Homo sapiens (Human) Peritoneal malignant mesothelioma
Ehrlich-Lettre ascites strain E
 Cell Line Info 
Mus musculus (Mouse) Malignant neoplasms of the mouse mammary gland
RAW 264.7
 Cell Line Info 
Mus musculus (Mouse) Mouse leukemia
L1210
 Cell Line Info 
Mus musculus (Mouse) Mouse leukemia
L1210/R81
 Cell Line Info 
Mus musculus (Mouse) Mouse leukemia
RAW-Lucia ISG
 Cell Line Info 
Mus musculus (Mouse) Mouse leukemia
RAW-Lucia ISG-KO-STING
 Cell Line Info 
Mus musculus (Mouse) Mouse leukemia
RAW 264
 Cell Line Info 
Mus musculus (Mouse) Mouse leukemia
J774
 Cell Line Info 
Mus musculus (Mouse) Mouse reticulum cell sarcoma
J774A1
 Cell Line Info 
Mus musculus (Mouse) Mouse reticulum cell sarcoma
HTC
 Cell Line Info 
Rattus norvegicus (Rat) Rat hepatocellular carcinoma