Brief Information of the Compound and Protein
Compound Name
2-[2-(4-adamantan-1-yl-phenoxy)-acetylamino]-N-(4-chloro-phenyl)-isonicotinamide
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PubChem ID
CID: 44443256
Canonical SMILES
Clc1ccc(NC(=O)c2ccnc(NC(=O)COc3ccc(cc3)C34CC5CC(CC(C5)C3)C4)c2)cc1
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Compound Formula C30H30ClN3O3
Compound Structure
Protein Name
Hypoxia-inducible factor 1-alpha
Protein Classification
Transcription factor
Uniprot ID
Q16665
Gene Name
HIF1A
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000275 AGS Homo sapiens (Human)  1
1
IC50 = 18600 nM
   TI
   LI
   LO
   TS
CL000273 Hep 3B2.1-7 Homo sapiens (Human)  1
1
IC50 > 30000 nM
   TI
   LI
   LO
   TS
CL000274 SK-HEP-1 Homo sapiens (Human)  1
1
IC50 = 2500 nM
   TI
   LI
   LO
   TS