Brief Information of the Cell Line and Protein
Cell Line ID: CL000274 , SK-HEP-1
Synonyms
SK-Hep-1
SK HEP-1
SK HEP 01
SK-Hep1
Sk-Hep1
SK Hep1
SKHEP-1
SKHEP1
SKHep1
SK_HEP1
Category Cancer cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_0525
Protein ID: PT06146 , Solute carrier family 12 member 5
Gene Name SLC12A5
Organism Rattus norvegicus, Rat
Protein Classification Transporter
Uniprot ID Q63633
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000274  Protein ID: PT06146
 
Compound ID Compound Name Compound Formula
CP0513963
benzyl 1-acetyl-2-[[4-methoxy-3-(trifluoromethyl)phenyl]methyl]pyrrolidine-2-carboxylate
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C23H24F3NO4
 1
1
IC50 = 50 nM
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CP0513281
benzyl 1-acetyl-2-[[4-fluoro-3-(trifluoromethyl)phenyl]methyl]pyrrolidine-2-carboxylate
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C22H21F4NO3
 1
1
IC50 = 60 nM
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CP0510050
benzyl 1-acetyl-2-[[3-(trifluoromethyl)phenyl]methyl]pyrrolidine-2-carboxylate
   Show/Hide
C22H22F3NO3
 1
1
IC50 = 80 nM
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CP0504389
benzyl 1-acetyl-2-[(4-cyanophenyl)methyl]pyrrolidine-2-carboxylate
   Show/Hide
C22H22N2O3
 1
1
IC50 = 160 nM
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CP0494471
benzyl 1-acetyl-2-[(4-fluorophenyl)methyl]pyrrolidine-2-carboxylate
   Show/Hide
C21H22FNO3
 1
1
IC50 = 200 nM
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CP0517416
1-[1-acetyl-2-[(4-fluorophenyl)methyl]pyrrolidin-2-yl]-3-(4-fluorophenyl)propan-1-one
   Show/Hide
C22H23F2NO2
 1
1
IC50 = 200 nM
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CP0523062
benzyl 1-acetyl-2-benzyl-3H-indole-2-carboxylate
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C25H23NO3
 1
1
IC50 = 200 nM
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CP0494474
benzyl 1-acetyl-2-[(3-methylsulfonylphenyl)methyl]pyrrolidine-2-carboxylate
   Show/Hide
C22H25NO5S
 1
1
IC50 = 250 nM
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CP0517415
benzyl (2R)-1-acetyl-2-benzylpyrrolidine-2-carboxylate
   Show/Hide
C21H23NO3
 1
1
IC50 = 300 nM
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CP0542398
1-(1-acetyl-2-benzylpyrrolidin-2-yl)-3-phenylpropan-1-one
   Show/Hide
C22H25NO2
 1
1
IC50 = 300 nM
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CP0430644
benzyl 1-acetyl-2-[(4-chlorophenyl)methyl]pyrrolidine-2-carboxylate
   Show/Hide
C21H22ClNO3
 1
1
IC50 = 320 nM
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CP0494473
benzyl 1-acetyl-2-[(3-cyanophenyl)methyl]pyrrolidine-2-carboxylate
   Show/Hide
C22H22N2O3
 1
1
IC50 = 320 nM
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CP0509607
benzyl 2-benzyl-1-(cyclopropanecarbonyl)pyrrolidine-2-carboxylate
   Show/Hide
C23H25NO3
 1
1
IC50 = 320 nM
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CP0438692
benzyl 1-acetyl-2-[(4-methoxyphenyl)methyl]pyrrolidine-2-carboxylate
   Show/Hide
C22H25NO4
 1
1
IC50 = 400 nM
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CP0504549
2-benzyl 1-methyl 2-benzylpyrrolidine-1,2-dicarboxylate
   Show/Hide
C21H23NO4
 1
1
IC50 = 400 nM
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CP0437774
3-(4-benzylpiperazine-1-carbonyl)-6-bromochromen-2-one
   Show/Hide
C21H19BrN2O3
 1
1
IC50 = 600 nM
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CP0491252
benzyl 1-acetyl-2-[[4-(trifluoromethyl)phenyl]methyl]pyrrolidine-2-carboxylate
   Show/Hide
C22H22F3NO3
 1
1
IC50 = 630 nM
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CP0429713
benzyl 1-acetyl-2-[(4-methylphenyl)methyl]pyrrolidine-2-carboxylate
   Show/Hide
C22H25NO3
 1
1
IC50 = 790 nM
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CP0452619
benzyl 1-acetyl-2-(thiophen-3-ylmethyl)pyrrolidine-2-carboxylate
   Show/Hide
C19H21NO3S
 1
1
IC50 = 790 nM
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CP0496106
4-methylbenzyl 1-acetyl-2-benzylpyrrolidine-2-carboxylate
   Show/Hide
C22H25NO3
 1
1
IC50 = 790 nM
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CP0418013
(+)-benzyl 1-acetyl-2-benzylpyrrolidine-2-carboxylate
   Show/Hide
C21H23NO3
 1
1
IC50 = 800 nM
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CP0510049
benzyl 1-acetyl-2-(cyclohexylmethyl)pyrrolidine-2-carboxylate
   Show/Hide
C21H29NO3
 1
1
IC50 = 1000 nM
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CP0523064
benzyl 3-benzyl-5-oxo-1,2,6,7,8,8a-hexahydroindolizine-3-carboxylate
   Show/Hide
C23H25NO3
 1
1
IC50 = 1000 nM
   TI
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CP0513282
benzyl 2-benzyl-1-propanoylpyrrolidine-2-carboxylate
   Show/Hide
C22H25NO3
 1
1
IC50 = 1200 nM
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CP0533060
4-chlorobenzyl 1-acetyl-2-benzylpyrrolidine-2-carboxylate
   Show/Hide
C21H22ClNO3
 1
1
IC50 = 1300 nM
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CP0487214
1-[2-benzyl-2-[(4R)-4-phenyl-4,5-dihydro-1,3-oxazol-2-yl]pyrrolidin-1-yl]ethanone
   Show/Hide
C22H24N2O2
 1
1
IC50 = 1300 nM
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CP0494660
benzyl 2-benzyl-1-methylsulfonylpyrrolidine-2-carboxylate
   Show/Hide
C20H23NO4S
 1
1
IC50 = 1600 nM
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CP0429712
benzyl 1-acetyl-2-(pyridin-4-ylmethyl)pyrrolidine-2-carboxylate
   Show/Hide
C20H22N2O3
 1
1
IC50 = 2000 nM
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CP0429714
benzyl 2-benzyl-1-(ethylcarbamoyl)pyrrolidine-2-carboxylate
   Show/Hide
C22H26N2O3
 1
1
IC50 = 2000 nM
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CP0513284
3-chlorobenzyl 1-acetyl-2-benzylpyrrolidine-2-carboxylate
   Show/Hide
C21H22ClNO3
 1
1
IC50 = 2500 nM
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CP0430684
benzyl 1-benzoyl-2-benzylpyrrolidine-2-carboxylate
   Show/Hide
C26H25NO3
 1
1
IC50 = 4000 nM
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CP0504390
benzyl 1-acetyl-2-[[4-fluoro-2-(trifluoromethyl)phenyl]methyl]pyrrolidine-2-carboxylate
   Show/Hide
C22H21F4NO3
 1
1
IC50 = 4000 nM
   TI
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CP0513283
1-phenylethyl 1-acetyl-2-benzylpyrrolidine-2-carboxylate
   Show/Hide
C22H25NO3
 1
1
IC50 = 4000 nM
   TI
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CP0527035
3-(4-benzylpiperazine-1-carbonyl)chromen-2-one
   Show/Hide
C21H20N2O3
 1
1
IC50 = 4000 nM
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CP0429753
4-(trifluoromethyl)benzyl 1-acetyl-2-benzylpyrrolidine-2-carboxylate
   Show/Hide
C22H22F3NO3
 1
1
IC50 = 5000 nM
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CP0504548
benzyl 1-acetyl-2-[(2-cyanophenyl)methyl]pyrrolidine-2-carboxylate
   Show/Hide
C22H22N2O3
 1
1
IC50 = 5000 nM
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CP0539297
2-chlorobenzyl 1-acetyl-2-benzylpyrrolidine-2-carboxylate
   Show/Hide
C21H22ClNO3
 1
1
IC50 = 6000 nM
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CP0514231
benzyl 1-acetyl-2-(2-phenylethyl)pyrrolidine-2-carboxylate
   Show/Hide
C22H25NO3
 1
1
IC50 = 8000 nM
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CP0504315
2-phenylethyl 1-acetyl-2-benzylpyrrolidine-2-carboxylate
   Show/Hide
C22H25NO3
 1
1
IC50 = 10000 nM
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CP0526075
1-[2-benzyl-2-(4-phenyl-1,3-oxazol-2-yl)pyrrolidin-1-yl]ethanone
   Show/Hide
C22H22N2O2
 1
1
IC50 = 12600 nM
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CP0523063
1-[2-benzyl-2-(phenylmethoxymethyl)pyrrolidin-1-yl]ethanone
   Show/Hide
C21H25NO2
 1
1
IC50 = 20000 nM
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CP0376377
1-acetyl-N,2-dibenzyl-N-methylpyrrolidine-2-carboxamide
   Show/Hide
C22H26N2O2
 1
1
IC50 = 32000 nM
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CP0523061
benzyl (2S)-1-acetyl-2-benzylpyrrolidine-2-carboxylate
   Show/Hide
C21H23NO3
 1
1
IC50 = 50000 nM
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CP0389731
cyclohexylmethyl 1-acetyl-2-benzylpyrrolidine-2-carboxylate
   Show/Hide
C21H29NO3
 1
1
IC50 = 63000 nM
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CP0518713
benzyl 1-acetyl-2-ethylpyrrolidine-2-carboxylate
   Show/Hide
C16H21NO3
 1
1
IC50 = 80000 nM
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CP0430645
1-acetyl-N,2-dibenzylpyrrolidine-2-carboxamide
   Show/Hide
C21H24N2O2
 1
1
IC50 = 100000 nM
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CP0430685
methyl 1-acetyl-2-benzylpyrrolidine-2-carboxylate
   Show/Hide
C15H19NO3
 1
1
IC50 > 100000 nM
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CP0438693
1-acetyl-2-benzylpyrrolidine-2-carboxylic acid
   Show/Hide
C14H17NO3
 1
1
IC50 > 100000 nM
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CP0494476
benzyl 2-benzylpyrrolidine-2-carboxylate
   Show/Hide
C19H21NO2
 1
1
IC50 > 100000 nM
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CP0510051
benzyl 2-benzyl-1-ethylpyrrolidine-2-carboxylate
   Show/Hide
C21H25NO2
 1
1
IC50 > 100000 nM
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CP0542620
pyridin-4-ylmethyl 1-acetyl-2-benzylpyrrolidine-2-carboxylate
   Show/Hide
C20H22N2O3
 1
1
IC50 > 100000 nM
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CP0542621
4-(methylsulfonyl)benzyl 1-acetyl-2-benzylpyrrolidine-2-carboxylate
   Show/Hide
C22H25NO5S
 1
1
IC50 > 100000 nM
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