General Information of the Cell Line
Cell Line ID
CL000431
Cell Line Name
SNU-16
Synonyms
SNU16
NCI-SNU-16
Category
Cancer cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_0076
Tissue Information
Ascites
Disease
Gastric adenocarcinoma (NCIt: C4004)
Map of Molecular Bioactivity Related to the Cell Line
Map of Molecular Bioactivity Related to the Cell Line

Cell Line
Protein
Compound

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Cell Line
Protein ID: PT01115, Fibroblast growth factor receptor 2
 Protein Info 
Compound ID Compound Name Compound Formula
CP0236837
 Compound Info 
N-[5-[2-(3,5-dimethoxyphenyl)ethyl]-1H-pyrazol-3-yl]-7-[(3R,5S)-3,4,5-trimethylpiperazin-1-yl]quinazolin-4-amine
   Show/Hide
C28H35N7O2
  1
1
IC50 < 0.1 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0549218
 Compound Info 
7-(4-cyclobutylpiperazin-1-yl)-N-[5-[2-(3,5-dimethoxyphenyl)ethyl]-1H-pyrazol-3-yl]quinazolin-4-amine
   Show/Hide
C29H35N7O2
  1
1
IC50 < 0.1 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0569655
 Compound Info 
N-[5-[2-(3,5-dimethoxyphenyl)ethyl]-1H-pyrazol-3-yl]-7-(4-propan-2-ylpiperazin-1-yl)quinazolin-4-amine
   Show/Hide
C28H35N7O2
  1
1
IC50 < 0.1 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0761938
 Compound Info 
N-(5-(3,5-Dimethoxyphenethyl)-1H-pyrazol-3-yl)-7-(4-methylpiperazin-1-yl)quinazolin-4-amine
   Show/Hide
C26H31N7O2
  1
1
IC50 = 0.7 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0047214
 Compound Info 
7-(1,3,4,6,7,8,9,9a-octahydropyrido[1,2-a]pyrazin-2-yl)-N-[5-[2-(3,5-dimethoxyphenyl)ethyl]-1H-pyrazol-3-yl]quinazolin-4-amine
   Show/Hide
C29H35N7O2
  1
1
IC50 = 0.8 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0122169
 Compound Info 
N-[5-[2-(3,5-dimethoxyphenyl)ethyl]-1H-pyrazol-3-yl]-7-(4-ethylpiperazin-1-yl)quinazolin-4-amine
   Show/Hide
C27H33N7O2
  1
1
IC50 = 1.2 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0549217
 Compound Info 
N-[5-[2-(2,6-dichloro-3,5-dimethoxyphenyl)ethyl]-1H-pyrazol-3-yl]-7-(4-ethylpiperazin-1-yl)quinazolin-4-amine
   Show/Hide
C27H31Cl2N7O2
  1
1
IC50 = 1.4 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0047221
 Compound Info 
N-[5-[2-(3,5-dimethoxyphenyl)ethyl]-1H-pyrazol-3-yl]-6-(4-ethylpiperazin-1-yl)isoquinolin-1-amine
   Show/Hide
C28H34N6O2
  1
1
IC50 = 1.8 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0054573
 Compound Info 
CHEBI:63453
   Show/Hide
C26H33N5O3
  2
1
IC50 = 3.6 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
2
IC50 = 25.4 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0047213
 Compound Info 
N-[5-[2-(3,5-dimethoxyphenyl)ethyl]-1H-pyrazol-3-yl]-7-morpholin-4-ylquinazolin-4-amine
   Show/Hide
C25H28N6O3
  1
1
IC50 = 3.9 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0121917
 Compound Info 
N-[5-[2-(3,5-dimethoxyphenyl)ethyl]-1H-pyrazol-3-yl]-7-(1-methylpiperidin-4-yl)quinazolin-4-amine
   Show/Hide
C27H32N6O2
  1
1
IC50 = 9 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0121918
 Compound Info 
N-[5-[2-(3,5-dimethoxyphenyl)ethyl]-1H-pyrazol-3-yl]-7-[3-(dimethylamino)pyrrolidin-1-yl]quinazolin-4-amine
   Show/Hide
C27H33N7O2
  1
1
IC50 = 10 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0090815
 Compound Info 
4-N-[5-[2-(3,5-dimethoxyphenyl)ethyl]-1H-pyrazol-3-yl]-7-N-(2-methoxyethyl)quinazoline-4,7-diamine
   Show/Hide
C24H28N6O3
  1
1
IC50 = 10.3 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0569656
 Compound Info 
N-[5-[2-(3,5-dimethoxyphenyl)ethyl]-1H-pyrazol-3-yl]-7-(4-methyl-1,4-diazepan-1-yl)quinazolin-4-amine
   Show/Hide
C27H33N7O2
  1
1
IC50 = 10.8 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0462436
 Compound Info 
4-N-[5-[2-(3,5-dimethoxyphenyl)ethyl]-1H-pyrazol-3-yl]-7-N-(2-morpholin-4-ylethyl)quinazoline-4,7-diamine
   Show/Hide
C27H33N7O3
  1
1
IC50 = 13.2 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0690841
 Compound Info 
N-(5-(3,5-Dimethoxyphenethyl)-1H-pyrazol-3-yl)-8-(4-ethylpiperazin-1-yl)quinazolin-4-amine
   Show/Hide
C27H33N7O2
  1
1
IC50 = 13.8 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0360545
 Compound Info 
N-[5-[2-(3,5-dimethoxyphenyl)ethyl]-1H-pyrazol-3-yl]-7-[4-(dimethylamino)piperidin-1-yl]quinazolin-4-amine
   Show/Hide
C28H35N7O2
  1
1
IC50 = 17.5 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0182382
 Compound Info 
N-[5-[2-(3,5-dimethoxyphenyl)ethyl]-1H-pyrazol-3-yl]-2-ethyl-7-(4-ethylpiperazin-1-yl)quinazolin-4-amine
   Show/Hide
C29H37N7O2
  1
1
IC50 = 24.7 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0081362
 Compound Info 
4-fluoro-2-[5-[[(1R)-2-hydroxy-1-phenylethyl]amino]-3-(3-methyl-2H-indazol-5-yl)pyridin-2-yl]phenol
   Show/Hide
C27H23FN4O2
  1
1
IC50 = 24.8 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0081381
 Compound Info 
4-chloro-2-[5-[[(1R)-2-hydroxy-1-phenylethyl]amino]-3-(3-methyl-2H-indazol-5-yl)pyridin-2-yl]phenol
   Show/Hide
C27H23ClN4O2
  1
1
IC50 = 24.8 nM
 Bioactivity Info 
   TI
   LI
   LO
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CP0099316
 Compound Info 
3-[5-[[(1R)-2-hydroxy-1-phenylethyl]amino]-3-(3-methyl-2H-indazol-5-yl)pyridin-2-yl]phenol
   Show/Hide
C27H24N4O2
  1
1
IC50 = 36.2 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0099314
 Compound Info 
2-[5-[[(1R)-2-hydroxy-1-phenylethyl]amino]-3-(3-methyl-2H-indazol-5-yl)pyridin-2-yl]phenol
   Show/Hide
C27H24N4O2
  1
1
IC50 = 57.5 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0133097
 Compound Info 
N-[5-[2-(3,5-dimethoxyphenyl)ethyl]-1H-pyrazol-3-yl]-7-(4-ethylpiperazin-1-yl)-2-propylquinazolin-4-amine
   Show/Hide
C30H39N7O2
  1
1
IC50 = 90 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0047216
 Compound Info 
N-[5-[2-(3,5-dimethoxyphenyl)ethyl]-1H-pyrazol-3-yl]-7-(4-ethylpiperazin-1-yl)-2-methylquinazolin-4-amine
   Show/Hide
C28H35N7O2
  1
1
IC50 = 105.7 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0569659
 Compound Info 
2-chloro-N-[5-[2-(3,5-dimethoxyphenyl)ethyl]-1H-pyrazol-3-yl]-7-(4-ethylpiperazin-1-yl)quinazolin-4-amine
   Show/Hide
C27H32ClN7O2
  1
1
IC50 = 108.2 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0081678
 Compound Info 
4-chloro-2-[5-[[(1R)-2-hydroxy-1-phenylethyl]amino]-3-isoquinolin-6-ylpyridin-2-yl]phenol
   Show/Hide
C28H22ClN3O2
  1
1
IC50 = 249 nM
 Bioactivity Info 
   TI
   LI
   LO
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CP0118716
 Compound Info 
2,4-difluoro-6-[5-[[(1R)-2-hydroxy-1-phenylethyl]amino]-3-(3-methyl-2H-indazol-5-yl)pyridin-2-yl]phenol
   Show/Hide
C27H22F2N4O2
  1
1
IC50 = 280.1 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0109337
 Compound Info 
4,5-difluoro-2-[5-[[(1R)-2-hydroxy-1-phenylethyl]amino]-3-(3-methyl-2H-indazol-5-yl)pyridin-2-yl]phenol
   Show/Hide
C27H22F2N4O2
  1
1
IC50 = 288.6 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0118715
 Compound Info 
2-fluoro-6-[5-[[(1R)-2-hydroxy-1-phenylethyl]amino]-3-(3-methyl-2H-indazol-5-yl)pyridin-2-yl]phenol
   Show/Hide
C27H23FN4O2
  1
1
IC50 = 293.5 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0109346
 Compound Info 
5-fluoro-2-[5-[[(1R)-2-hydroxy-1-phenylethyl]amino]-3-(3-methyl-2H-indazol-5-yl)pyridin-2-yl]phenol
   Show/Hide
C27H23FN4O2
  1
1
IC50 = 313.3 nM
 Bioactivity Info 
   TI
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CP0109448
 Compound Info 
(2R)-2-[[5-(3-methyl-2H-indazol-5-yl)-6-phenylpyridin-3-yl]amino]-2-phenylethanol
   Show/Hide
C27H24N4O
  1
1
IC50 = 677.7 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0234743
 Compound Info 
4-chloro-2-[5-[[(1R)-2-hydroxy-1-phenylethyl]amino]-3-(3-methyl-2H-pyrazolo[3,4-b]pyridin-5-yl)pyridin-2-yl]phenol
   Show/Hide
C26H22ClN5O2
  1
1
IC50 = 2281.3 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0121920
 Compound Info 
4-N-[5-[2-(3,5-dimethoxyphenyl)ethyl]-1H-pyrazol-3-yl]-7-(4-ethylpiperazin-1-yl)-2-N-[(3-methyl-1,2-oxazol-5-yl)methyl]quinazoline-2,4-diamine
   Show/Hide
C32H39N9O3
  1
1
IC50 > 100 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0653199
 Compound Info 
N-(5-(3,5-Dimethoxyphenethyl)-1H-pyrazol-3-yl)quinazolin-4-amine
   Show/Hide
C21H21N5O2
  1
1
IC50 > 200 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0717956
 Compound Info 
5-Chloro-N-(5-(3,5-dimethoxyphenethyl)-1H-pyrazol-3-yl)quinazolin-4-amine
   Show/Hide
C21H20ClN5O2
  1
1
IC50 > 200 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0734490
 Compound Info 
N-(5-(3,5-Dimethoxyphenethyl)-1H-pyrazol-3-yl)-8-methoxyquinazolin-4-amine
   Show/Hide
C22H23N5O3
  1
1
IC50 > 200 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0734491
 Compound Info 
8-Chloro-N-(5-(3,5-dimethoxyphenethyl)-1H-pyrazol-3-yl)quinazolin-4-amine
   Show/Hide
C21H20ClN5O2
  1
1
IC50 > 200 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0961526
 Compound Info 
N-(5-(3,5-Dimethoxyphenethyl)-1H-pyrazol-3-yl)-5-methoxyquinazolin-4-amine
   Show/Hide
C22H23N5O3
  1
1
IC50 > 200 nM
 Bioactivity Info 
   TI
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   TS
Cell Viability or Cytotoxicity Assay
Compound ID Compound Name Compound Formula
CP0548604
 Compound Info 
7-[N-(cyclopropylmethyl)-3,5-dimethoxyanilino]-3-(1-methylpyrazol-4-yl)pyrido[1,2-a]pyrimidin-4-one
   Show/Hide
 C24H25N5O3  1
1
IC50 = 3.1 nM
   TI
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CP0549253
 Compound Info 
3-[1-(1-acetylazetidin-3-yl)pyrazol-4-yl]-7-[3,5-dimethoxy-N-[2-(propan-2-ylamino)ethyl]anilino]pyrido[1,2-a]pyrimidin-4-one
   Show/Hide
 C29H35N7O4  1
1
IC50 = 4.4 nM
   TI
   LI
   LO
   TS
Protein family and CMB statistics Related to the Cell Line
Cell Lines Derived from the same Tissue Source (Ascites)
Cell Line Name Organism Disease
PEO1
 Cell Line Info 
Homo sapiens (Human) BRCA2-associated hereditary breast and ovarian cancer syndrome
MAST
 Cell Line Info 
Homo sapiens (Human) Breast carcinoma
Ramos
 Cell Line Info 
Homo sapiens (Human) Burkitt lymphoma
CA46
 Cell Line Info 
Homo sapiens (Human) Burkitt lymphoma
CellSensor STAT6-bla RA-1
 Cell Line Info 
Homo sapiens (Human) Burkitt lymphoma
NCI-H716
 Cell Line Info 
Homo sapiens (Human) Cecum adenocarcinoma
COLO 205
 Cell Line Info 
Homo sapiens (Human) Colon adenocarcinoma
COLO 201
 Cell Line Info 
Homo sapiens (Human) Colon adenocarcinoma
DiFi
 Cell Line Info 
Homo sapiens (Human) Colorectal carcinoma
U-2932
 Cell Line Info 
Homo sapiens (Human) Diffuse large B-cell lymphoma activated B-cell type
DB
 Cell Line Info 
Homo sapiens (Human) Diffuse large B-cell lymphoma germinal center B-cell type
HEC-50B
 Cell Line Info 
Homo sapiens (Human) Endometrial adenocarcinoma
SNU-5
 Cell Line Info 
Homo sapiens (Human) Gastric adenocarcinoma
SNU-620
 Cell Line Info 
Homo sapiens (Human) Gastric adenocarcinoma
SNU-638
 Cell Line Info 
Homo sapiens (Human) Gastric adenocarcinoma
SNU-668
 Cell Line Info 
Homo sapiens (Human) Gastric signet ring cell adenocarcinoma
OVCAR-3
 Cell Line Info 
Homo sapiens (Human) High grade ovarian serous adenocarcinoma
OVCAR-5
 Cell Line Info 
Homo sapiens (Human) High grade ovarian serous adenocarcinoma
COV318
 Cell Line Info 
Homo sapiens (Human) High grade ovarian serous adenocarcinoma
ZR-75-1
 Cell Line Info 
Homo sapiens (Human) Invasive breast carcinoma of no special type
SK-HEP-1
 Cell Line Info 
Homo sapiens (Human) Liver and intrahepatic bile duct epithelial neoplasm
OV-90
 Cell Line Info 
Homo sapiens (Human) Ovarian adenocarcinoma
LK2
 Cell Line Info 
Homo sapiens (Human) Ovarian carcinoma
RMG-I
 Cell Line Info 
Homo sapiens (Human) Ovarian clear cell adenocarcinoma
PA-1
 Cell Line Info 
Homo sapiens (Human) Ovarian mixed germ cell tumor
SK-OV-3
 Cell Line Info 
Homo sapiens (Human) Ovarian serous cystadenocarcinoma
SKOV3/TR
 Cell Line Info 
Homo sapiens (Human) Ovarian serous cystadenocarcinoma
AsPC-1
 Cell Line Info 
Homo sapiens (Human) Pancreatic ductal adenocarcinoma
HEC
 Cell Line Info 
Homo sapiens (Human) Peritoneal malignant mesothelioma
Ehrlich-Lettre ascites strain E
 Cell Line Info 
Mus musculus (Mouse) Malignant neoplasms of the mouse mammary gland
RAW 264.7
 Cell Line Info 
Mus musculus (Mouse) Mouse leukemia
L1210
 Cell Line Info 
Mus musculus (Mouse) Mouse leukemia
L1210/R81
 Cell Line Info 
Mus musculus (Mouse) Mouse leukemia
RAW-Lucia ISG
 Cell Line Info 
Mus musculus (Mouse) Mouse leukemia
RAW-Lucia ISG-KO-STING
 Cell Line Info 
Mus musculus (Mouse) Mouse leukemia
RAW 264
 Cell Line Info 
Mus musculus (Mouse) Mouse leukemia
J774
 Cell Line Info 
Mus musculus (Mouse) Mouse reticulum cell sarcoma
J774A1
 Cell Line Info 
Mus musculus (Mouse) Mouse reticulum cell sarcoma
HTC
 Cell Line Info 
Rattus norvegicus (Rat) Rat hepatocellular carcinoma