Brief Information of the Compound and Protein
Compound Name
N-(5-(3,5-Dimethoxyphenethyl)-1H-pyrazol-3-yl)-8-(4-ethylpiperazin-1-yl)quinazolin-4-amine
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PubChem ID
CID: 127045749
Canonical SMILES
CCN1CCN(c2cccc3c(Nc4cc(CCc5cc(OC)cc(OC)c5)[nH]n4)ncnc23)CC1
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Compound Formula C27H33N7O2
Compound Structure
Protein Name
Fibroblast growth factor receptor 2
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase FGFR family
Uniprot ID
P21802
Gene Name
FGFR2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000431 SNU-16 Homo sapiens (Human)  1
1
IC50 = 13.8 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 4.3 nM