General Information of the Cell Line
Cell Line ID
CL000014
Cell Line Name
RAW 264.7
Synonyms
RAW264
RAW2647
RAW264.7
RAW-264.7
Raw 264.7
Raw264.7
Category
Cancer cell line
Organism
Mus musculus (Mouse)
Cellosaurus ID
CVCL_0493
Tissue Information
Ascites
Disease
Mouse leukemia (NCIt: C21604)
Map of Molecular Bioactivity Related to the Cell Line
Map of Molecular Bioactivity Related to the Cell Line

Cell Line
Protein
Compound

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Cell Line
Protein ID: PT07292, C5a anaphylatoxin chemotactic receptor 1
 Protein Info 
Compound ID Compound Name Compound Formula
CP0494936
 Compound Info 
(2S)-2-[[(2R)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-1-[(2S)-2-[[(2S)-2-acetamido-3-phenylpropanoyl]amino]-6-aminohexanoyl]pyrrolidine-2-carbonyl]amino]-4-methylpentanoyl]amino]propanoyl]amino]butanoyl]amino]propanoyl]amino]-5-(diaminomethylideneamino)pentanoic acid
   Show/Hide
C44H72N12O10
  1
1
EC50 = 2300 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0494930
 Compound Info 
(2S)-2-[[(2R)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-1-[(2S)-2-[[(2S)-2-acetamido-3-phenylpropanoyl]amino]-6-aminohexanoyl]pyrrolidine-2-carbonyl]amino]-4-methylpentanoyl]amino]propanoyl]amino]propanoyl]amino]propanoyl]amino]-5-(diaminomethylideneamino)pentanoic acid
   Show/Hide
C43H70N12O10
  1
1
EC50 = 22900 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
Protein ID: PT06605, C5a anaphylatoxin chemotactic receptor 1
 Protein Info 
Protein ID: PT03954, Calmodulin-sensitive adenylate cyclase
 Protein Info 
Protein ID: PT05669, Ceramide glucosyltransferase
 Protein Info 
Protein ID: PT03331, Glucocorticoid receptor
 Protein Info 
Protein ID: PT03854, HTH-type transcriptional regulator EthR
 Protein Info 
Protein ID: PT01240, Lethal factor
 Protein Info 
Protein ID: PT02655, Mitogen-activated protein kinase 14
 Protein Info 
Protein ID: PT06456, Mitogen-activated protein kinase 8
 Protein Info 
Protein ID: PT01718, Nitric oxide synthase, inducible
 Protein Info 
Protein ID: PT05838, Prostaglandin E synthase
 Protein Info 
Protein ID: PT01062, Prostaglandin G/H synthase 2
 Protein Info 
Protein ID: PT01029, Serine/threonine protein kinase PIK3CG
 Protein Info 
Protein ID: PT03071, Serine/threonine protein kinase PIK3CG
 Protein Info 
Protein ID: PT06227, Serine/threonine-protein kinase TBK1
 Protein Info 
Protein ID: PT05006, Stimulator of interferon genes protein
 Protein Info 
Protein ID: PT06516, TNF-alpha convertase
 Protein Info 
Protein ID: PT03141, Toll-like receptor 2
 Protein Info 
Protein ID: PT03041, Toll-like receptor 4
 Protein Info 
Protein ID: PT03589, Toll-like receptor 7
 Protein Info 
Cell Viability or Cytotoxicity Assay
Compound ID Compound Name Compound Formula
CP0005367
 Compound Info 
2-(4-fluorophenyl)-N,N-dimethyl-3-(2-methylsulfanylpyrimidin-4-yl)imidazo[1,2-a]pyrazin-8-amine
   Show/Hide
 C19H17FN6S  1
1
CC50 = 36500 nM
   TI
   LI
   LO
   TS
CP0005820
 Compound Info 
2-(4-fluorophenyl)-N,N-dimethyl-3-pyrimidin-5-ylimidazo[1,2-a]pyrazin-8-amine
   Show/Hide
 C18H15FN6  1
1
CC50 = 39120 nM
   TI
   LI
   LO
   TS
CP0010057
 Compound Info 
2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl-1H-indol-3-yl}acetic acid
   Show/Hide
 C19H16ClNO4  2
1
IC50 > 80000 nM
   TI
   LI
   LO
   TS
2
IC50 > 100000 nM
   TI
   LI
   LO
   TS
CP0058540
 Compound Info 
PRUNETIN
   Show/Hide
 C16H12O5  1
1
CC50 > 100000 nM
   TI
   LI
   LO
   TS
CP0150660
 Compound Info 
(2S)-5-hydroxy-2-(4-hydroxyphenyl)-7-methoxy-2,3-dihydro-4H-chromen-4-one
   Show/Hide
 C16H14O5  1
1
CC50 > 100000 nM
   TI
   LI
   LO
   TS
CP0382558
 Compound Info 
US8754233, 2-(5-Amino-3-methyl-1H-pyrazol-4-yl)-5-fluoro-benzothiazole-6-sulfonic acid amide
   Show/Hide
 C11H10FN5O2S2  1
1
IC50 = 6700 nM
   TI
   LI
   LO
   TS
CP0391496
 Compound Info 
US8754233, 5-(4-Amino-phenyl)-4-benzothiazol-2-yl-2H-pyrazol-3-ylamine
   Show/Hide
 C16H13N5S  1
1
IC50 = 21300 nM
   TI
   LI
   LO
   TS
CP0398195
 Compound Info 
N-(3-chlorophenyl)-2-[4-[(Z)-[3-[3-(dimethylamino)-2-methylpropyl]-2,4-dioxo-1,3-thiazolidin-5-ylidene]methyl]phenoxy]acetamide
   Show/Hide
 C24H26ClN3O4S  1
1
IC50 > 80000 nM
   TI
   LI
   LO
   TS
CP0407710
 Compound Info 
US8754233, 2-(5-Amino-3-methyl-1H-pyrazol-4-yl)-5-fluoro-benzothiazole-4-sulfonicacid (2-hydroxy-ethyl)-amide
   Show/Hide
 C13H14FN5O3S2  1
1
IC50 > 25000 nM
   TI
   LI
   LO
   TS
CP0425830
 Compound Info 
(Z)-N-(3-Chlorophenyl)-2-(4-((2,4-dioxothiazolidin-5-ylidene)methyl)phenoxy)acetamide
   Show/Hide
 C18H13ClN2O4S  1
1
IC50 > 100000 nM
   TI
   LI
   LO
   TS
CP0428708
 Compound Info 
(E)-3-(4-bromophenyl)-1-(5-hydroxy-2,2-dimethylchromen-6-yl)prop-2-en-1-one
   Show/Hide
 C20H17BrO3  1
1
IC50 > 80000 nM
   TI
   LI
   LO
   TS
CP0435418
 Compound Info 
(E)-3-(3-fluorophenyl)-1-(5-hydroxy-2,2-dimethylchromen-6-yl)prop-2-en-1-one
   Show/Hide
 C20H17FO3  1
1
IC50 > 80000 nM
   TI
   LI
   LO
   TS
CP0444191
 Compound Info 
2-[(5Z)-5-[[4-[2-(3-chloroanilino)-2-oxoethoxy]phenyl]methylidene]-4-oxo-2-sulfanylidene-1,3-thiazolidin-3-yl]acetic acid
   Show/Hide
 C20H15ClN2O5S2  1
1
IC50 > 80000 nM
   TI
   LI
   LO
   TS
CP0445428
 Compound Info 
(E)-3-(3,4-dimethoxyphenyl)-1-(5-hydroxy-2,2-dimethylchromen-6-yl)prop-2-en-1-one
   Show/Hide
 C22H22O5  1
1
IC50 > 80000 nM
   TI
   LI
   LO
   TS
CP0459929
 Compound Info 
2-chloro-1-[5-(5-methoxy-2,2-dimethylchromen-8-yl)-3-(3,4,5-trimethoxyphenyl)-3,4-dihydropyrazol-2-yl]ethanone
   Show/Hide
 C26H29ClN2O6  1
1
IC50 = 30800 nM
   TI
   LI
   LO
   TS
CP0461009
 Compound Info 
2-[4-[(Z)-(1-benzyl-2,5-dioxoimidazolidin-4-ylidene)methyl]phenoxy]-N-(3-chlorophenyl)acetamide
   Show/Hide
 C25H20ClN3O4  1
1
IC50 > 80000 nM
   TI
   LI
   LO
   TS
CP0462842
 Compound Info 
(Z)-N-(3,4-Difluorophenyl)-2-(4-((2,4-dioxothiazolidin-5-ylidene)methyl)phenoxy)acetamide
   Show/Hide
 C18H12F2N2O4S  1
1
IC50 > 100000 nM
   TI
   LI
   LO
   TS
CP0470056
 Compound Info 
US8754233, 4-Benzothiazol-2-yl-5-piperazin-1-yl-2H-pyrazol-3-ylamine
   Show/Hide
 C14H16N6S  1
1
IC50 > 25000 nM
   TI
   LI
   LO
   TS
CP0495128
 Compound Info 
(Z)-2-(4-((2,4-Dioxothiazolidin-5-ylidene)methyl)phenoxy)-N-(naphthalen-1-yl)acetamide
   Show/Hide
 C22H16N2O4S  1
1
IC50 = 54970 nM
   TI
   LI
   LO
   TS
CP0524258
 Compound Info 
US8754233, 4-(5-Fluoro-6-methoxy-benzothiazol-2-yl)-5-methyl-1H-pyrazol-3-ylamine
   Show/Hide
 C12H11FN4OS  1
1
IC50 > 25000 nM
   TI
   LI
   LO
   TS
CP0538099
 Compound Info 
US8754233, N-[2-(5-Amino-3-methyl-1H-pyrazol-4-yl)-benzothiazol-6-yl]-acetamide
   Show/Hide
 C13H13N5OS  1
1
IC50 = 18400 nM
   TI
   LI
   LO
   TS
CP0544737
 Compound Info 
US8754233, 4-(6-Methoxy-benzothiazol-2-yl)-5-methyl-1H-pyrazol-3-ylamine
   Show/Hide
 C12H12N4OS  1
1
IC50 = 21100 nM
   TI
   LI
   LO
   TS
CP0545228
 Compound Info 
US8754233, 2-(5-Amino-3-methyl-1H-pyrazol-4-yl)-5-fluoro-benzothiazole-6-sulfonic acid (pyridin-4-ylmethyl)-amide
   Show/Hide
 C17H15FN6O2S2  1
1
IC50 = 23400 nM
   TI
   LI
   LO
   TS
CP0546836
 Compound Info 
US8754233, 3-(5-Amino-4-benzothiazol-2-yl-1H-pyrazol-3-ylamino)-propan-1-ol
   Show/Hide
 C13H15N5OS  1
1
IC50 > 25000 nM
   TI
   LI
   LO
   TS
CP0549369
 Compound Info 
US8754233, 2-(5-Amino-3-methyl-1H-pyrazol-4-yl)-benzothiazole-6-sulfonic acid [2-(4-amino-phenyl)-ethyl]-amide
   Show/Hide
 C19H20N6O2S2  1
1
IC50 > 25000 nM
   TI
   LI
   LO
   TS
CP0558426
 Compound Info 
4-[[2-[(E)-2-(3,4,5-trimethoxyphenyl)ethenyl]thieno[3,2-d]pyrimidin-4-yl]amino]phenol
   Show/Hide
 C23H21N3O4S  1
1
IC50 > 50000 nM
   TI
   LI
   LO
   TS
CP0572211
 Compound Info 
N-[(4-methylphenyl)methyl]-2-[(E)-2-(3,4,5-trimethoxyphenyl)ethenyl]thieno[3,2-d]pyrimidin-4-amine
   Show/Hide
 C25H25N3O3S  1
1
IC50 > 50000 nM
   TI
   LI
   LO
   TS
Protein family and CMB statistics Related to the Cell Line
Cell Lines Derived from the same Tissue Source (Ascites)
Cell Line Name Organism Disease
PEO1
 Cell Line Info 
Homo sapiens (Human) BRCA2-associated hereditary breast and ovarian cancer syndrome
MAST
 Cell Line Info 
Homo sapiens (Human) Breast carcinoma
Ramos
 Cell Line Info 
Homo sapiens (Human) Burkitt lymphoma
CA46
 Cell Line Info 
Homo sapiens (Human) Burkitt lymphoma
CellSensor STAT6-bla RA-1
 Cell Line Info 
Homo sapiens (Human) Burkitt lymphoma
NCI-H716
 Cell Line Info 
Homo sapiens (Human) Cecum adenocarcinoma
COLO 205
 Cell Line Info 
Homo sapiens (Human) Colon adenocarcinoma
COLO 201
 Cell Line Info 
Homo sapiens (Human) Colon adenocarcinoma
DiFi
 Cell Line Info 
Homo sapiens (Human) Colorectal carcinoma
U-2932
 Cell Line Info 
Homo sapiens (Human) Diffuse large B-cell lymphoma activated B-cell type
DB
 Cell Line Info 
Homo sapiens (Human) Diffuse large B-cell lymphoma germinal center B-cell type
HEC-50B
 Cell Line Info 
Homo sapiens (Human) Endometrial adenocarcinoma
SNU-5
 Cell Line Info 
Homo sapiens (Human) Gastric adenocarcinoma
SNU-16
 Cell Line Info 
Homo sapiens (Human) Gastric adenocarcinoma
SNU-620
 Cell Line Info 
Homo sapiens (Human) Gastric adenocarcinoma
SNU-638
 Cell Line Info 
Homo sapiens (Human) Gastric adenocarcinoma
SNU-668
 Cell Line Info 
Homo sapiens (Human) Gastric signet ring cell adenocarcinoma
OVCAR-3
 Cell Line Info 
Homo sapiens (Human) High grade ovarian serous adenocarcinoma
OVCAR-5
 Cell Line Info 
Homo sapiens (Human) High grade ovarian serous adenocarcinoma
COV318
 Cell Line Info 
Homo sapiens (Human) High grade ovarian serous adenocarcinoma
ZR-75-1
 Cell Line Info 
Homo sapiens (Human) Invasive breast carcinoma of no special type
SK-HEP-1
 Cell Line Info 
Homo sapiens (Human) Liver and intrahepatic bile duct epithelial neoplasm
OV-90
 Cell Line Info 
Homo sapiens (Human) Ovarian adenocarcinoma
LK2
 Cell Line Info 
Homo sapiens (Human) Ovarian carcinoma
RMG-I
 Cell Line Info 
Homo sapiens (Human) Ovarian clear cell adenocarcinoma
PA-1
 Cell Line Info 
Homo sapiens (Human) Ovarian mixed germ cell tumor
SK-OV-3
 Cell Line Info 
Homo sapiens (Human) Ovarian serous cystadenocarcinoma
SKOV3/TR
 Cell Line Info 
Homo sapiens (Human) Ovarian serous cystadenocarcinoma
AsPC-1
 Cell Line Info 
Homo sapiens (Human) Pancreatic ductal adenocarcinoma
HEC
 Cell Line Info 
Homo sapiens (Human) Peritoneal malignant mesothelioma
Ehrlich-Lettre ascites strain E
 Cell Line Info 
Mus musculus (Mouse) Malignant neoplasms of the mouse mammary gland
L1210
 Cell Line Info 
Mus musculus (Mouse) Mouse leukemia
L1210/R81
 Cell Line Info 
Mus musculus (Mouse) Mouse leukemia
RAW-Lucia ISG
 Cell Line Info 
Mus musculus (Mouse) Mouse leukemia
RAW-Lucia ISG-KO-STING
 Cell Line Info 
Mus musculus (Mouse) Mouse leukemia
RAW 264
 Cell Line Info 
Mus musculus (Mouse) Mouse leukemia
J774
 Cell Line Info 
Mus musculus (Mouse) Mouse reticulum cell sarcoma
J774A1
 Cell Line Info 
Mus musculus (Mouse) Mouse reticulum cell sarcoma
HTC
 Cell Line Info 
Rattus norvegicus (Rat) Rat hepatocellular carcinoma