| Compound ID |
Compound Name |
Compound Formula |
|
CP0455223
|
3-amino-6-[4-chloro-3-(phenylsulfamoyl)phenyl]-N-methylpyrazine-2-carboxamide
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|
C18H16ClN5O3S
|
1
|
| 1 |
IC50 = 69 nM
|
|
|
|
CP0456942
|
3-amino-6-[4-chloro-3-[(3-fluorophenyl)sulfamoyl]phenyl]-N-methylpyrazine-2-carboxamide
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|
C18H15ClFN5O3S
|
1
|
| 1 |
IC50 = 171 nM
|
|
|
|
CP0381346
|
5-[3-[4-[3-(4-propan-2-ylphenyl)pyrazin-2-yl]piperazin-1-yl]sulfonylphenyl]pyrimidin-2-amine
Show/Hide
|
C27H29N7O2S
|
1
|
| 1 |
IC50 = 182 nM
|
|
|
|
CP0433674
|
3-amino-6-[4-chloro-3-[(3-chlorophenyl)sulfamoyl]phenyl]-N-methylpyrazine-2-carboxamide
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|
C18H15Cl2N5O3S
|
1
|
| 1 |
IC50 = 184 nM
|
|
|
|
CP0481681
|
5-[3-[4-[2-(4-propan-2-ylphenyl)pyridin-3-yl]piperazin-1-yl]sulfonylphenyl]pyrimidin-2-amine
Show/Hide
|
C28H30N6O2S
|
1
|
| 1 |
IC50 = 213 nM
|
|
|
|
CP0453880
|
5-[3-[4-[3-(4-methoxyphenyl)pyrazin-2-yl]piperazin-1-yl]sulfonylphenyl]pyrimidin-2-amine
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|
C25H25N7O3S
|
1
|
| 1 |
IC50 = 264 nM
|
|
|
|
CP0007893
|
4-[2-(1H-indazol-4-yl)-6-[(4-methanesulfonylpiperazin-1-yl)methyl]thieno[3,2-d]pyrimidin-4-yl]morpholine
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|
C23H27N7O3S2
|
1
|
| 1 |
IC50 = 298 nM
|
|
|
|
CP0456949
|
3-amino-N-methyl-6-[3-(phenylsulfamoyl)phenyl]pyrazine-2-carboxamide
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|
C18H17N5O3S
|
1
|
| 1 |
IC50 = 326 nM
|
|
|
|
CP0413763
|
3-amino-6-[4-chloro-3-[(4-chlorophenyl)sulfamoyl]phenyl]-N-methylpyrazine-2-carboxamide
Show/Hide
|
C18H15Cl2N5O3S
|
1
|
| 1 |
IC50 = 394 nM
|
|
|
|
CP0381386
|
3-amino-6-[3-[(3-chlorophenyl)sulfamoyl]phenyl]-N-methylpyrazine-2-carboxamide
Show/Hide
|
C18H16ClN5O3S
|
1
|
| 1 |
IC50 = 409 nM
|
|
|
|
CP0413761
|
3-amino-6-[4-chloro-3-[(3-methoxyphenyl)sulfamoyl]phenyl]-N-methylpyrazine-2-carboxamide
Show/Hide
|
C19H18ClN5O4S
|
1
|
| 1 |
IC50 = 431 nM
|
|
|
|
CP0381347
|
3-amino-6-[4-chloro-3-[(2,4-dichlorophenyl)sulfamoyl]phenyl]-N-methylpyrazine-2-carboxamide
Show/Hide
|
C18H14Cl3N5O3S
|
1
|
| 1 |
IC50 = 464 nM
|
|
|
|
CP0413762
|
3-amino-6-[4-chloro-3-[(2-chlorophenyl)sulfamoyl]phenyl]-N-methylpyrazine-2-carboxamide
Show/Hide
|
C18H15Cl2N5O3S
|
1
|
| 1 |
IC50 = 507 nM
|
|
|
|
CP0456951
|
3-amino-6-[4-chloro-3-[(2-chloro-4-fluorophenyl)sulfamoyl]phenyl]-N-methylpyrazine-2-carboxamide
Show/Hide
|
C18H14Cl2FN5O3S
|
1
|
| 1 |
IC50 = 528 nM
|
|
|
|
CP0484882
|
3-amino-6-[4-chloro-3-[[3-(trifluoromethyl)phenyl]sulfamoyl]phenyl]-N-methylpyrazine-2-carboxamide
Show/Hide
|
C19H15ClF3N5O3S
|
1
|
| 1 |
IC50 = 552 nM
|
|
|
|
CP0413764
|
3-amino-6-[4-chloro-3-[(3-methylphenyl)sulfamoyl]phenyl]-N-methylpyrazine-2-carboxamide
Show/Hide
|
C19H18ClN5O3S
|
1
|
| 1 |
IC50 = 572 nM
|
|
|
|
CP0456948
|
3-amino-6-[4-chloro-3-[(2,3-dichlorophenyl)sulfamoyl]phenyl]-N-methylpyrazine-2-carboxamide
Show/Hide
|
C18H14Cl3N5O3S
|
1
|
| 1 |
IC50 = 587 nM
|
|
|
|
CP0027760
|
3-amino-6-[4-chloro-3-[(2,3-difluorophenyl)sulfamoyl]phenyl]-N-methylpyrazine-2-carboxamide
Show/Hide
|
C18H14ClF2N5O3S
|
1
|
| 1 |
IC50 = 773 nM
|
|
|
|
CP0020253
|
3-amino-6-[4-chloro-3-[(3-fluoro-2-methylphenyl)sulfamoyl]phenyl]-N-methylpyrazine-2-carboxamide
Show/Hide
|
C19H17ClFN5O3S
|
1
|
| 1 |
IC50 = 805 nM
|
|
|
|
CP0484883
|
3-amino-6-[4-chloro-3-[(2-chloro-3-fluorophenyl)sulfamoyl]phenyl]-N-methylpyrazine-2-carboxamide
Show/Hide
|
C18H14Cl2FN5O3S
|
1
|
| 1 |
IC50 = 1575 nM
|
|
|
|
CP0453882
|
3-amino-6-[3-[(2,3-difluorophenyl)sulfamoyl]phenyl]-N-methylpyrazine-2-carboxamide
Show/Hide
|
C18H15F2N5O3S
|
1
|
| 1 |
IC50 = 1877 nM
|
|
|
|
CP0453879
|
2-(4-methoxyphenyl)-3-[4-[3-(4-methoxyphenyl)phenyl]sulfonylpiperazin-1-yl]pyrazine
Show/Hide
|
C28H28N4O4S
|
1
|
| 1 |
IC50 = 3608 nM
|
|
|
|
CP0433672
|
3-amino-N-methyl-6-[3-(trifluoromethyl)phenyl]pyrazine-2-carboxamide
Show/Hide
|
C13H11F3N4O
|
1
|
| 1 |
IC50 = 5430 nM
|
|
|
|
CP0111428
|
2-[(1-methylbenzimidazol-2-yl)methyl]-4-morpholin-4-yl-1H-pyrimidin-6-one
Show/Hide
|
C17H19N5O2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0456945
|
3-amino-N-methyl-6-[3-(2H-tetrazol-5-yl)phenyl]pyrazine-2-carboxamide
Show/Hide
|
C13H12N8O
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0003061
|
9-(1-anilinoethyl)-7-methyl-2-morpholin-4-ylpyrido[1,2-a]pyrimidin-4-one
Show/Hide
|
C21H24N4O2
|
1
|
| 1 |
IC50 > 1000 nM
|
|
|
