| Compound ID |
Compound Name |
Compound Formula |
|
CP0565382
|
4-(1-bicyclo[1.1.1]pentanylamino)-2-[(4-hydroxycyclohexyl)amino]pyrimidine-5-carboxamide
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|
C16H23N5O2
|
1
|
| 1 |
IC50 = 170 nM
|
|
|
|
CP0555732
|
4-(1-bicyclo[1.1.1]pentanylamino)-2-[[(1R,3S)-3-hydroxycyclohexyl]amino]pyrimidine-5-carboxamide
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|
C16H23N5O2
|
1
|
| 1 |
IC50 = 210 nM
|
|
|
|
CP0228900
|
4-anilino-2-[(4-hydroxycyclohexyl)amino]pyrimidine-5-carboxamide
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|
C17H21N5O2
|
1
|
| 1 |
IC50 = 212 nM
|
|
|
|
CP0566900
|
4-(tert-butylamino)-2-[(4-hydroxycyclohexyl)amino]pyrimidine-5-carboxamide
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|
C15H25N5O2
|
1
|
| 1 |
IC50 = 350 nM
|
|
|
|
CP0494233
|
4-[[(1R,3S)-3-hydroxycyclohexyl]amino]-2-[(4-methoxycyclohexyl)amino]pyrimidine-5-carboxamide
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|
C18H29N5O3
|
1
|
| 1 |
IC50 = 400 nM
|
|
|
|
CP0542317
|
4-[[(1R,3R,4R)-3-hydroxy-4-methylcyclohexyl]amino]-2-[(1-methylcyclopropyl)amino]pyrimidine-5-carboxamide
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|
C16H25N5O2
|
1
|
| 1 |
IC50 = 550 nM
|
|
|
|
CP0549243
|
4-[[(1R,3R)-3-hydroxycyclohexyl]amino]-2-[(4-methoxycyclohexyl)amino]pyrimidine-5-carboxamide
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|
C18H29N5O3
|
1
|
| 1 |
IC50 = 580 nM
|
|
|
|
CP0076539
|
4-[[9-[(3S)-oxolan-3-yl]-8-(2,4,6-trifluoroanilino)purin-2-yl]amino]cyclohexan-1-ol
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|
C21H23F3N6O2
|
1
|
| 1 |
IC50 = 1120 nM
|
|
|
|
CP0367988
|
4-anilino-2-(3,4-dimethoxyanilino)pyrimidine-5-carboxamide
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|
C19H19N5O3
|
1
|
| 1 |
IC50 = 1450 nM
|
|
|
|
CP0557724
|
2-[(4-hydroxycyclohexyl)amino]-4-(propan-2-ylamino)pyrimidine-5-carboxamide
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|
C14H23N5O2
|
1
|
| 1 |
IC50 = 1770 nM
|
|
|
|
CP0542316
|
2-[(4-methoxycyclohexyl)amino]-4-(propan-2-ylamino)pyrimidine-5-carboxamide
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|
C15H25N5O2
|
1
|
| 1 |
IC50 = 2390 nM
|
|
|
|
CP0557725
|
4-[[(1S,3S)-3-hydroxycyclohexyl]amino]-2-[(4-methoxycyclohexyl)amino]pyrimidine-5-carboxamide
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|
C18H29N5O3
|
1
|
| 1 |
IC50 = 6800 nM
|
|
|
|
CP0189537
|
4-[[(1S,3R)-3-hydroxycyclohexyl]amino]-2-[(4-methoxycyclohexyl)amino]pyrimidine-5-carboxamide
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|
C18H29N5O3
|
1
|
| 1 |
IC50 = 10100 nM
|
|
|
