Brief Information of the Compound and Protein
Compound Name
4-[[9-[(3S)-oxolan-3-yl]-8-(2,4,6-trifluoroanilino)purin-2-yl]amino]cyclohexan-1-ol
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PubChem ID
SID: 56402244
Canonical SMILES
O[C@H]1CC[C@@H](CC1)Nc1ncc2nc(Nc3c(F)cc(F)cc3F)n([C@H]3CCOC3)c2n1
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Compound Formula C21H23F3N6O2
Compound Structure
Protein Name
Mitogen-activated protein kinase 8
Protein Classification
Enzyme
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Kinase
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Protein Kinase
>
CMGC protein kinase group
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CMGC protein kinase MAPK family
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CMGC protein kinase JNK subfamily
Uniprot ID
Q91Y86
Gene Name
MAPK8
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000014 RAW 264.7 Mus musculus (Mouse)  1
1
IC50 = 1120 nM
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