Brief Information of the Compound and Protein
Compound Name
4-anilino-2-(3,4-dimethoxyanilino)pyrimidine-5-carboxamide
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PubChem ID
CID: 66576633
SID: 152257668
Canonical SMILES
COc1ccc(Nc2ncc(C(N)=O)c(Nc3ccccc3)n2)cc1OC
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Compound Formula C19H19N5O3
Compound Structure
Protein Name
Mitogen-activated protein kinase 8
Protein Classification
Enzyme
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Kinase
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Protein Kinase
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CMGC protein kinase group
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CMGC protein kinase MAPK family
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CMGC protein kinase JNK subfamily
Uniprot ID
Q91Y86
Gene Name
MAPK8
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000014 RAW 264.7 Mus musculus (Mouse)  1
1
IC50 = 1450 nM
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