Brief Information of the Compound and Protein
Compound Name
2-[(4-hydroxycyclohexyl)amino]-4-(propan-2-ylamino)pyrimidine-5-carboxamide
    Show/Hide
Canonical SMILES
CC(C)Nc1nc(N[C@H]2CC[C@H](O)CC2)ncc1C(N)=O
    Show/Hide
Compound Formula C14H23N5O2
Compound Structure
Protein Name
Mitogen-activated protein kinase 8
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
CMGC protein kinase group
>
CMGC protein kinase MAPK family
>
CMGC protein kinase JNK subfamily
Uniprot ID
Q91Y86
Gene Name
MAPK8
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000014 RAW 264.7 Mus musculus (Mouse)  1
1
IC50 = 1770 nM
   TI
   LI
   LO
   TS