Brief Information of the Compound and Protein
Compound Name
4-(1-bicyclo[1.1.1]pentanylamino)-2-[[(1R,3S)-3-hydroxycyclohexyl]amino]pyrimidine-5-carboxamide
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PubChem ID
CID: 71237291
Canonical SMILES
NC(=O)c1cnc(N[C@@H]2CCC[C@H](O)C2)nc1NC12CC(C1)C2
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Compound Formula C16H23N5O2
Compound Structure
Protein Name
Mitogen-activated protein kinase 8
Protein Classification
Enzyme
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Kinase
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Protein Kinase
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CMGC protein kinase group
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CMGC protein kinase MAPK family
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CMGC protein kinase JNK subfamily
Uniprot ID
Q91Y86
Gene Name
MAPK8
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000014 RAW 264.7 Mus musculus (Mouse)  1
1
IC50 = 210 nM
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