General Information of the Cell Line
Cell Line ID
CL000496
Cell Line Name
AsPC-1
Synonyms
AsPc-1
Aspc-1
ASPC-1
As-PC1
ASPC1
AsPC1
Aspc1
AsPc1
Category
Cancer cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_0152
Tissue Information
Ascites
Disease
Pancreatic ductal adenocarcinoma (NCIt: C9120)
Map of Molecular Bioactivity Related to the Cell Line
Map of Molecular Bioactivity Related to the Cell Line

Cell Line
Protein
Compound

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Cell Line
Protein ID: PT03462, GTPase KRas
 Protein Info 
Compound ID Compound Name Compound Formula
CP0569904
 Compound Info 
2-[(3R,8R,11S,14S,20S,23S,26S,29S,32S,35S,38S,39S)-3-[[(2S)-2-[[(2S)-2-[[(2S)-2-acetamido-6-azidohexanoyl]amino]-5-carbamimidamidopentanoyl]amino]-5-carbamimidamidopentanoyl]amino]-8-[[(2S)-1-[[(2S)-1-amino-5-carbamimidamido-1-oxopentan-2-yl]amino]-5-carbamimidamido-1-oxopentan-2-yl]carbamoyl]-29-[(2S)-butan-2-yl]-26-(hydroxymethyl)-23-[(4-hydroxyphenyl)methyl]-35-(2-methylpropyl)-2,10,13,19,22,25,28,31,34,37-decaoxo-39-phenyl-32-[(4-phenylphenyl)methyl]-11-propan-2-yl-5,6-dithia-1,9,12,18,21,24,27,30,33,36-decazatricyclo[36.3.0.014,18]hentetracontan-20-yl]acetic acid
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C102H152N32O21S2
  2
1
IC50 = 2700 nM
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2
IC50 = 19000 nM
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CP0544030
 Compound Info 
2-[(4R,9R,12S,15S,21S,24S,27S,30S,33S,36S,39S,40R)-4-[[(2S)-2-[[(2S)-2-acetamido-5-carbamimidamidopentanoyl]amino]-5-carbamimidamidopentanoyl]amino]-9-[[(2S)-1-[[(2S)-1-amino-5-carbamimidamido-1-oxopentan-2-yl]amino]-5-carbamimidamido-1-oxopentan-2-yl]carbamoyl]-30-[(2S)-butan-2-yl]-27-(hydroxymethyl)-24-[(4-hydroxyphenyl)methyl]-36-(2-methylpropyl)-3,11,14,20,23,26,29,32,35,38-decaoxo-40-phenyl-33-[(4-phenylphenyl)methyl]-12-propan-2-yl-6,7-dithia-1,10,13,19,22,25,28,31,34,37-decazatricyclo[37.3.0.015,19]dotetracontan-21-yl]acetic acid
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C97H144N28O20S2
  2
1
IC50 = 3300 nM
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2
IC50 = 33000 nM
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CP0579406
 Compound Info 
2-[(3R,8R,11S,14S,20S,23S,26S,29S,32S,35S,38S,41S,42S)-3-[[(2S)-2-[[(2S)-2-acetamido-5-carbamimidamidopentanoyl]amino]-5-carbamimidamidopentanoyl]amino]-8-[[(2S)-1-[[(2S)-1-amino-5-carbamimidamido-1-oxopentan-2-yl]amino]-5-carbamimidamido-1-oxopentan-2-yl]carbamoyl]-32-[(2S)-butan-2-yl]-26-(hydroxymethyl)-23-[(4-hydroxyphenyl)methyl]-29-methyl-38-(2-methylpropyl)-2,10,13,19,22,25,28,31,34,37,40-undecaoxo-42-phenyl-35-[(4-phenylphenyl)methyl]-11-propan-2-yl-5,6-dithia-1,9,12,18,21,24,27,30,33,36,39-undecazatricyclo[39.3.0.014,18]tetratetracontan-20-yl]acetic acid
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C99H147N29O21S2
  2
1
IC50 = 3800 nM
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2
IC50 = 3900 nM
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CP0544029
 Compound Info 
2-[(3R,8R,11S,14S,20S,23S,26S,29S,32S,35S,38S,39R)-3-[[(2S)-2-[[(2S)-2-[[(2S)-2-acetamido-6-azidohexanoyl]amino]-5-carbamimidamidopentanoyl]amino]-5-carbamimidamidopentanoyl]amino]-8-[[(2S)-1-[[(2S)-1-amino-5-carbamimidamido-1-oxopentan-2-yl]amino]-5-carbamimidamido-1-oxopentan-2-yl]carbamoyl]-26-(hydroxymethyl)-23-[(4-hydroxyphenyl)methyl]-29-methyl-35-(2-methylpropyl)-2,10,13,19,22,25,28,31,34,37-decaoxo-39-phenyl-32-[(4-phenylphenyl)methyl]-11-propan-2-yl-5,6-dithia-1,9,12,18,21,24,27,30,33,36-decazatricyclo[36.3.0.014,18]hentetracontan-20-yl]acetic acid
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C99H146N32O21S2
  2
1
IC50 = 6200 nM
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2
IC50 = 6800 nM
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CP0568539
 Compound Info 
2-[(4R,9R,12S,15S,21S,24S,27S,30S,33S,36S,39S,40R)-4-[[(2S)-2-[[(2S)-2-acetamido-5-carbamimidamidopentanoyl]amino]-5-carbamimidamidopentanoyl]amino]-9-[[(2S)-1-[[(2S)-1-amino-5-carbamimidamido-1-oxopentan-2-yl]amino]-5-carbamimidamido-1-oxopentan-2-yl]carbamoyl]-30-[(2S)-butan-2-yl]-27-(hydroxymethyl)-24-[(4-hydroxyphenyl)methyl]-36-(2-methylpropyl)-3,11,14,20,23,26,29,32,35,38-decaoxo-12-pentyl-40-phenyl-33-[(4-phenylphenyl)methyl]-6,7-dithia-1,10,13,19,22,25,28,31,34,37-decazatricyclo[37.3.0.015,19]dotetracontan-21-yl]acetic acid
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C99H148N28O20S2
  2
1
IC50 = 6800 nM
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2
IC50 = 29000 nM
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CP0567489
 Compound Info 
2-[(4R,9R,12S,15S,21S,24S,27S,30S,33S,36S,39S,40S)-4-[[(2S)-2-[[(2S)-2-acetamido-5-carbamimidamidopentanoyl]amino]-5-carbamimidamidopentanoyl]amino]-9-[[(2S)-1-[[(2S)-1-amino-5-carbamimidamido-1-oxopentan-2-yl]amino]-5-carbamimidamido-1-oxopentan-2-yl]carbamoyl]-30-[(2S)-butan-2-yl]-27-(hydroxymethyl)-24-[(4-hydroxyphenyl)methyl]-36-(2-methylpropyl)-3,11,14,20,23,26,29,32,35,38-decaoxo-33-[(4-phenylphenyl)methyl]-12-propan-2-yl-40-prop-2-enyl-6,7-dithia-1,10,13,19,22,25,28,31,34,37-decazatricyclo[37.3.0.015,19]dotetracontan-21-yl]acetic acid
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C94H144N28O20S2
  2
1
IC50 = 28000 nM
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2
IC50 > 50000 nM
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CP0571629
 Compound Info 
2-[(4R,9R,12S,15S,21S,24S,27S,30S,33S,36S,39S,40S)-4-[[(2S)-2-[[(2S)-2-acetamido-5-carbamimidamidopentanoyl]amino]-5-carbamimidamidopentanoyl]amino]-9-[[(2S)-1-[[(2S)-1-amino-5-carbamimidamido-1-oxopentan-2-yl]amino]-5-carbamimidamido-1-oxopentan-2-yl]carbamoyl]-30-[(2S)-butan-2-yl]-27-(hydroxymethyl)-24-[(4-hydroxyphenyl)methyl]-36-(2-methylpropyl)-3,11,14,20,23,26,29,32,35,38-decaoxo-12-pentyl-33-[(4-phenylphenyl)methyl]-40-prop-2-enyl-6,7-dithia-1,10,13,19,22,25,28,31,34,37-decazatricyclo[37.3.0.015,19]dotetracontan-21-yl]acetic acid
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C96H148N28O20S2
  2
1
IC50 = 30000 nM
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2
IC50 > 50000 nM
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Protein ID: PT01675, Wee1-like protein kinase
 Protein Info 
Cell Viability or Cytotoxicity Assay
Compound ID Compound Name Compound Formula
CP0003832
 Compound Info 
N'-hydroxy-N-phenyloctanediamide
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 C14H20N2O3  1
1
IC50 = 100000 nM
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CP0117454
 Compound Info 
2-(5-chloro-2-(2-methoxy-4-morpholinophenylamino)pyrimidin-4-ylamino)-N-methylbenzamide
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 C23H25ClN6O3  1
1
IC50 = 6730 nM
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CP0151685
 Compound Info 
N-(2-aminophenyl)-4-[[4-methyl-3-[(4-pyridin-3-ylpyrimidin-2-yl)amino]anilino]methyl]benzamide
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 C30H27N7O  1
1
IC50 = 7940 nM
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CP0173297
 Compound Info 
3-[3-(benzofuran-2-carbonyl)phenyl]-N-hydroxyacrylamide
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 C18H13NO4  1
1
IC50 = 3500 nM
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CP0185310
 Compound Info 
(E)-N-hydroxy-3-[3-(1H-indole-2-carbonyl)phenyl]prop-2-enamide
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 C18H14N2O3  1
1
IC50 = 3900 nM
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CP0204863
 Compound Info 
(E)-N-hydroxy-3-(4-((4-methyl-3-(4-(pyridin-3-yl)pyrimidin-2-ylamino)phenylamino)methyl)phenyl)acrylamide
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 C26H24N6O2  2
1
IC50 = 6309.57 nM
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2
IC50 = 6310 nM
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CP0382251
 Compound Info 
N-[2-(4-cyano-3-fluorophenyl)phenyl]-4-methoxybenzenesulfonamide
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 C20H15FN2O3S  1
1
GI50 = 20 nM
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CP0397754
 Compound Info 
2-[[5-chloro-2-[4-(1-morpholin-4-yl-1-oxobutan-2-yl)oxyanilino]pyrimidin-4-yl]amino]-N-methylbenzamide
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 C26H29ClN6O4  1
1
IC50 = 2600 nM
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CP0397755
 Compound Info 
2-[[5-chloro-2-[4-(2-morpholin-4-yl-2-oxoethyl)sulfanylanilino]pyrimidin-4-yl]amino]-N-methylbenzamide
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 C24H25ClN6O3S  1
1
IC50 = 1220 nM
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CP0416866
 Compound Info 
3-methoxy-N-[2-[2-methoxy-4-(4-methylpiperazin-1-yl)-5-(prop-2-enoylamino)anilino]pyrimidin-4-yl]benzamide
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 C27H31N7O4  1
1
IC50 > 10000 nM
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CP0431822
 Compound Info 
3-[(Z)-[1-[4-(4-cyclohexylpiperazin-1-yl)butyl]-2H-indol-3-ylidene]amino]-1,1-dimethylthiourea
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 C25H40N6S  1
1
EC50 = 3860 nM
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CP0437743
 Compound Info 
N-(4-chlorophenyl)sulfonyl-2-methyl-2-[4-[2-(4-phenyldiazenylphenoxy)ethyl]phenoxy]propanamide
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 C30H28ClN3O5S  1
1
CC50 > 24000 nM
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CP0475073
 Compound Info 
2-[[5-chloro-2-[4-[(4-fluorophenyl)sulfonylamino]anilino]pyrimidin-4-yl]amino]-N-methylbenzamide
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 C24H20ClFN6O3S  1
1
IC50 = 3920 nM
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CP0519012
 Compound Info 
2-[[5-chloro-2-[4-(1-morpholin-4-yl-1-oxopropan-2-yl)oxyanilino]pyrimidin-4-yl]amino]-N-methylbenzamide
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 C25H27ClN6O4  1
1
IC50 = 2870 nM
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CP0529687
 Compound Info 
2-[[5-chloro-2-[4-(2-morpholin-4-yl-2-oxoethoxy)anilino]pyrimidin-4-yl]amino]-N-methylbenzamide
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 C24H25ClN6O4  1
1
IC50 = 1750 nM
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CP0534582
 Compound Info 
N-[2-(4-fluorophenyl)phenyl]-4-methoxybenzenesulfonamide
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 C19H16FNO3S  1
1
GI50 = 300 nM
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CP0545974
 Compound Info 
2-[[5-chloro-2-[4-(diethoxyphosphorylmethyl)anilino]pyrimidin-4-yl]amino]-N-methylbenzamide
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 C23H27ClN5O4P  1
1
IC50 = 3310 nM
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CP0557022
 Compound Info 
N-[2-(4-cyanophenyl)phenyl]-4-methoxybenzenesulfonamide
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 C20H16N2O3S  1
1
GI50 = 30 nM
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CP0562554
 Compound Info 
N-[2-[4-[2-(dimethylamino)ethyl-methylamino]-2-methoxy-5-(prop-2-enoylamino)anilino]pyrimidin-4-yl]-3-methoxybenzamide
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 C27H33N7O4  1
1
IC50 = 3401 nM
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CP0564443
 Compound Info 
2-[[5-chloro-2-[4-[(4-fluorophenyl)sulfonylamino]-3-methoxyanilino]pyrimidin-4-yl]amino]-N-methylbenzamide
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 C25H22ClFN6O4S  1
1
IC50 = 6690 nM
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CP0564773
 Compound Info 
2-[[5-chloro-2-[4-[4-(trifluoromethylsulfonylamino)phenoxy]anilino]pyrimidin-4-yl]amino]-N-methylbenzamide
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 C25H20ClF3N6O4S  1
1
IC50 = 2390 nM
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CP0575085
 Compound Info 
2-[[5-chloro-2-[4-(2-morpholin-4-yl-2-oxoethoxy)anilino]pyrimidin-4-yl]amino]-N-cyclopropylbenzamide
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 C26H27ClN6O4  1
1
IC50 > 10000 nM
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CP0965525
 Compound Info 
(2S,3S,4S)-2-((R)-2-amino-1-((2S,3R,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3,4-dimethoxytetrahydrofuran-2-yl)-2-oxoethoxy)-3,4-dihydroxy-N-((S)-2-oxoazepan-3-yl)-3,4-dihydro-2H-pyran-6-carboxamide
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 C24H33N5O12  1
1
IC50 > 50000 nM
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Protein family and CMB statistics Related to the Cell Line
Cell Lines Derived from the same Tissue Source (Ascites)
Cell Line Name Organism Disease
PEO1
 Cell Line Info 
Homo sapiens (Human) BRCA2-associated hereditary breast and ovarian cancer syndrome
MAST
 Cell Line Info 
Homo sapiens (Human) Breast carcinoma
Ramos
 Cell Line Info 
Homo sapiens (Human) Burkitt lymphoma
CA46
 Cell Line Info 
Homo sapiens (Human) Burkitt lymphoma
CellSensor STAT6-bla RA-1
 Cell Line Info 
Homo sapiens (Human) Burkitt lymphoma
NCI-H716
 Cell Line Info 
Homo sapiens (Human) Cecum adenocarcinoma
COLO 205
 Cell Line Info 
Homo sapiens (Human) Colon adenocarcinoma
COLO 201
 Cell Line Info 
Homo sapiens (Human) Colon adenocarcinoma
DiFi
 Cell Line Info 
Homo sapiens (Human) Colorectal carcinoma
U-2932
 Cell Line Info 
Homo sapiens (Human) Diffuse large B-cell lymphoma activated B-cell type
DB
 Cell Line Info 
Homo sapiens (Human) Diffuse large B-cell lymphoma germinal center B-cell type
HEC-50B
 Cell Line Info 
Homo sapiens (Human) Endometrial adenocarcinoma
SNU-5
 Cell Line Info 
Homo sapiens (Human) Gastric adenocarcinoma
SNU-16
 Cell Line Info 
Homo sapiens (Human) Gastric adenocarcinoma
SNU-620
 Cell Line Info 
Homo sapiens (Human) Gastric adenocarcinoma
SNU-638
 Cell Line Info 
Homo sapiens (Human) Gastric adenocarcinoma
SNU-668
 Cell Line Info 
Homo sapiens (Human) Gastric signet ring cell adenocarcinoma
OVCAR-3
 Cell Line Info 
Homo sapiens (Human) High grade ovarian serous adenocarcinoma
OVCAR-5
 Cell Line Info 
Homo sapiens (Human) High grade ovarian serous adenocarcinoma
COV318
 Cell Line Info 
Homo sapiens (Human) High grade ovarian serous adenocarcinoma
ZR-75-1
 Cell Line Info 
Homo sapiens (Human) Invasive breast carcinoma of no special type
SK-HEP-1
 Cell Line Info 
Homo sapiens (Human) Liver and intrahepatic bile duct epithelial neoplasm
OV-90
 Cell Line Info 
Homo sapiens (Human) Ovarian adenocarcinoma
LK2
 Cell Line Info 
Homo sapiens (Human) Ovarian carcinoma
RMG-I
 Cell Line Info 
Homo sapiens (Human) Ovarian clear cell adenocarcinoma
PA-1
 Cell Line Info 
Homo sapiens (Human) Ovarian mixed germ cell tumor
SK-OV-3
 Cell Line Info 
Homo sapiens (Human) Ovarian serous cystadenocarcinoma
SKOV3/TR
 Cell Line Info 
Homo sapiens (Human) Ovarian serous cystadenocarcinoma
HEC
 Cell Line Info 
Homo sapiens (Human) Peritoneal malignant mesothelioma
Ehrlich-Lettre ascites strain E
 Cell Line Info 
Mus musculus (Mouse) Malignant neoplasms of the mouse mammary gland
RAW 264.7
 Cell Line Info 
Mus musculus (Mouse) Mouse leukemia
L1210
 Cell Line Info 
Mus musculus (Mouse) Mouse leukemia
L1210/R81
 Cell Line Info 
Mus musculus (Mouse) Mouse leukemia
RAW-Lucia ISG
 Cell Line Info 
Mus musculus (Mouse) Mouse leukemia
RAW-Lucia ISG-KO-STING
 Cell Line Info 
Mus musculus (Mouse) Mouse leukemia
RAW 264
 Cell Line Info 
Mus musculus (Mouse) Mouse leukemia
J774
 Cell Line Info 
Mus musculus (Mouse) Mouse reticulum cell sarcoma
J774A1
 Cell Line Info 
Mus musculus (Mouse) Mouse reticulum cell sarcoma
HTC
 Cell Line Info 
Rattus norvegicus (Rat) Rat hepatocellular carcinoma