General Information of the Cell Line
Cell Line ID
CL000158
Cell Line Name
J774
Synonyms
J-774
Category
Cancer cell line
Organism
Mus musculus (Mouse)
Cellosaurus ID
CVCL_4692
Tissue Information
Ascites
Disease
Mouse reticulum cell sarcoma (NCIt: C134780)
Map of Molecular Bioactivity Related to the Cell Line
Map of Molecular Bioactivity Related to the Cell Line

Cell Line
Protein
Compound

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Cell Line
Protein ID: PT06394, Oxysterols receptor LXR-beta
Compound ID Compound Name Compound Formula
CP0244920
biarylether alcohol quinoline, 5b
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C32H26F3NO2
 1
1
EC50 = 12 nM
   TI
   LI
   LO
   TS
CP0003740
N-[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl]-N-(2,2,2-trifluoroethyl)benzenesulfonamide
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C17H12F9NO3S
 1
1
EC50 = 27 nM
   TI
   LI
   LO
   TS
CP0180321
biarylether alcohol quinoline, 5i
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C25H22ClNO2
 1
1
EC50 = 37 nM
   TI
   LI
   LO
   TS
CP0203734
2-(4-{3-[3-benzyl-8-(trifluoromethyl)quinolin-4-yl]phenoxymethyl}phenyl)acetic acid
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C32H24F3NO3
 1
1
EC50 = 41 nM
   TI
   LI
   LO
   TS
CP0069743
biarylether alcohol quinoline, 5a
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C30H22F3NO2
 1
1
EC50 = 111 nM
   TI
   LI
   LO
   TS
CP0341708
biarylether alcohol quinoline, 5d
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C29H20F3NO2
 1
1
EC50 = 141 nM
   TI
   LI
   LO
   TS
CP0225856
biarylether alcohol quinoline, 5e
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C28H20ClNO2
 1
1
EC50 = 168 nM
   TI
   LI
   LO
   TS
CP0353477
biarylether alcohol quinoline, 5f
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C24H18F3NO2
 1
1
EC50 = 555 nM
   TI
   LI
   LO
   TS
CP0106853
biarylether alcohol quinoline, 5h
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C23H18ClNO2
 1
1
EC50 > 1000 nM
   TI
   LI
   LO
   TS
CP0106854
biarylether alcohol quinoline, 5c
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C29H20F3NO2
 1
1
EC50 > 1000 nM
   TI
   LI
   LO
   TS
CP0225855
biarylether alcohol quinoline, 5g
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C24H18F3NO2
 1
1
EC50 > 1000 nM
   TI
   LI
   LO
   TS
Protein family and CMB statistics Related to the Cell Line
Cell Lines Derived from the same Tissue Source (Ascites)
Cell Line Name Organism Disease
PEO1 Homo sapiens (Human) BRCA2-associated hereditary breast and ovarian cancer syndrome
MAST Homo sapiens (Human) Breast carcinoma
Ramos Homo sapiens (Human) Burkitt lymphoma
CA46 Homo sapiens (Human) Burkitt lymphoma
CellSensor STAT6-bla RA-1 Homo sapiens (Human) Burkitt lymphoma
NCI-H716 Homo sapiens (Human) Cecum adenocarcinoma
COLO 205 Homo sapiens (Human) Colon adenocarcinoma
COLO 201 Homo sapiens (Human) Colon adenocarcinoma
DiFi Homo sapiens (Human) Colorectal carcinoma
U-2932 Homo sapiens (Human) Diffuse large B-cell lymphoma activated B-cell type
DB Homo sapiens (Human) Diffuse large B-cell lymphoma germinal center B-cell type
HEC-50B Homo sapiens (Human) Endometrial adenocarcinoma
SNU-5 Homo sapiens (Human) Gastric adenocarcinoma
SNU-16 Homo sapiens (Human) Gastric adenocarcinoma
SNU-620 Homo sapiens (Human) Gastric adenocarcinoma
SNU-638 Homo sapiens (Human) Gastric adenocarcinoma
SNU-668 Homo sapiens (Human) Gastric signet ring cell adenocarcinoma
OVCAR-3 Homo sapiens (Human) High grade ovarian serous adenocarcinoma
OVCAR-5 Homo sapiens (Human) High grade ovarian serous adenocarcinoma
COV318 Homo sapiens (Human) High grade ovarian serous adenocarcinoma
ZR-75-1 Homo sapiens (Human) Invasive breast carcinoma of no special type
SK-HEP-1 Homo sapiens (Human) Liver and intrahepatic bile duct epithelial neoplasm
OV-90 Homo sapiens (Human) Ovarian adenocarcinoma
LK2 Homo sapiens (Human) Ovarian carcinoma
RMG-I Homo sapiens (Human) Ovarian clear cell adenocarcinoma
PA-1 Homo sapiens (Human) Ovarian mixed germ cell tumor
SK-OV-3 Homo sapiens (Human) Ovarian serous cystadenocarcinoma
SKOV3/TR Homo sapiens (Human) Ovarian serous cystadenocarcinoma
AsPC-1 Homo sapiens (Human) Pancreatic ductal adenocarcinoma
HEC Homo sapiens (Human) Peritoneal malignant mesothelioma
Ehrlich-Lettre ascites strain E Mus musculus (Mouse) Malignant neoplasms of the mouse mammary gland
RAW 264.7 Mus musculus (Mouse) Mouse leukemia
L1210 Mus musculus (Mouse) Mouse leukemia
L1210/R81 Mus musculus (Mouse) Mouse leukemia
RAW-Lucia ISG Mus musculus (Mouse) Mouse leukemia
RAW-Lucia ISG-KO-STING Mus musculus (Mouse) Mouse leukemia
RAW 264 Mus musculus (Mouse) Mouse leukemia
J774A1 Mus musculus (Mouse) Mouse reticulum cell sarcoma
HTC Rattus norvegicus (Rat) Rat hepatocellular carcinoma