Compound ID |
Compound Name |
Compound Formula |
CP0014938
|
(5-fluorouracil)5-Fluoro-1H-pyrimidine-2,4-dione
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|
C4H3FN2O2
|
1
|
1 |
IC50 = 1300 nM
|
|
|
CP0015449
|
4,7-dihydroxy-11-methylbenzo[a]pyrrolo[3,4-c]carbazole-1,3-(2H,8H)-dione
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|
C19H12N2O4
|
1
|
1 |
IC50 = 600 nM
|
|
|
CP0036197
|
2-[(4-{[(2,4-diaminopteridin-6-yl)methyl](methyl)amino}phenyl)formamido]pentanedioic acid
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|
C20H22N8O5
|
6
|
1 |
IC50 = 2.1 nM
|
|
|
2 |
IC50 = 12 nM
|
|
|
3 |
IC50 = 24 nM
|
|
|
4 |
IC50 = 30 nM
|
|
|
5 |
IC50 = 1300 nM
|
|
|
6 |
IC50 = 220000 nM
|
|
|
CP0047751
|
2-{4-[1-(2,4-Diamino-pteridin-6-ylmethyl)-propyl]-benzoylamino}-pentanedioic acid
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|
C22H25N7O5
|
1
|
1 |
IC50 = 65 nM
|
|
|
CP0048297
|
3-[(3S)-3-aminopyrrolidine-1-carbonyl]-4,11-dihydroxy-2-methylnaphtho[2,3-f][1]benzofuran-5,10-dione;methanesulfonic acid
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|
C23H22N2O9S
|
1
|
1 |
IC50 = 600 nM
|
|
|
CP0053031
|
4-Aminofolic acid
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|
C19H20N8O5
|
2
|
1 |
EC50 = 1.8 nM
|
|
|
2 |
IC50 = 3 nM
|
|
|
CP0057341
|
(6RS) 2-{4-[2-(2-Amino-5-ethyl-4-oxo-3,4,5,6,7,8-hexahydro-pyrido[2,3-d]pyrimidin-6-yl)-ethyl]-benzoylamino}-pentanedioic acid
Show/Hide
|
C23H29N5O6
|
1
|
1 |
IC50 = 57.2 nM
|
|
|
CP0077456
|
1-(beta-D-2-deoxy-erythro-pentofuranosyl)-5-fluorouracil
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|
C9H11FN2O5
|
4
|
1 |
IC50 = 0.63 nM
|
|
|
2 |
IC50 = 2.3 nM
|
|
|
3 |
IC50 = 12 nM
|
|
|
4 |
IC50 = 23 nM
|
|
|
CP0083030
|
11H-2,5,11-triaza-benzo[a]trindene-1,3,4,6-tetraone
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|
C16H7N3O4
|
1
|
1 |
IC50 = 32700 nM
|
|
|
CP0088766
|
(S)-2-{4-[2-(2,4-Diamino-pteridin-6-yl)-ethyl]-benzoylamino}-pentanedioic acid
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|
C20H21N7O5
|
1
|
1 |
IC50 = 1.5 nM
|
|
|
CP0111571
|
4-(2-Benzenesulfonylamino-1-methyl-2-oxo-ethylcarbamoyl)-2-{4-[(2-methyl-4-oxo-4,6,7,8-tetrahydro-3H-cyclopenta[g]quinazolin-6-yl)-prop-2-ynyl-amino]-benzoylamino}-butyric acid
Show/Hide
|
C36H36N6O8S
|
1
|
1 |
IC50 = 8200 nM
|
|
|
CP0175672
|
2-{4-[(2-Amino-4-oxo-1,4,5,6,7,8-hexahydro-quinazolin-6-ylmethyl)-amino]-benzoylamino}-pentanedioic acid
Show/Hide
|
C21H25N5O6
|
1
|
1 |
IC50 = 57.2 nM
|
|
|
CP0185067
|
2-{4-[2-(2,4-Diamino-pteridin-6-yl)-propyl]-benzoylamino}-pentanedioic acid
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|
C21H23N7O5
|
1
|
1 |
IC50 = 0.24 nM
|
|
|
CP0205751
|
2-[2-[[11-(3-aminopropylamino)-5,10-dioxonaphtho[2,3-f][1]benzothiol-4-yl]amino]ethyl]guanidine;hydrochloride
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|
C22H25ClN6O2S
|
1
|
1 |
IC50 = 10000 nM
|
|
|
CP0208036
|
2-{4-[(2-Methyl-4-oxo-4,6,7,8-tetrahydro-3H-cyclopenta[g]quinazolin-6-yl)-prop-2-ynyl-amino]-benzoylamino}-4-[1-(1H-tetrazol-5-yl)-ethylcarbamoyl]-butyric acid
Show/Hide
|
C30H31N9O5
|
2
|
1 |
IC50 = 640 nM
|
|
|
2 |
IC50 = 1600 nM
|
|
|
CP0244326
|
(R)-2-((S)-4-Carboxy-4-{4-[(2,7-dimethyl-4-oxo-3,4-dihydro-quinazolin-6-ylmethyl)-prop-2-ynyl-amino]-benzoylamino}-butyrylamino)-pentanedioic acid; TFA
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|
C31H33N5O9
|
1
|
1 |
IC50 = 14000 nM
|
|
|
CP0246021
|
2-{4-[2-(2,4-Diamino-pteridin-6-yl)-butyl]-benzoylamino}-pentanedioic acid
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|
C22H25N7O5
|
1
|
1 |
IC50 = 4.7 nM
|
|
|
CP0259513
|
(S)-2-{4-[(2-Methyl-4-oxo-4,6,7,8-tetrahydro-3H-cyclopenta[g]quinazolin-6-yl)-prop-2-ynyl-amino]-benzoylamino}-5-(1H-[1,2,4]triazole-3-sulfonyl)-pentanoic acid
Show/Hide
|
C29H29N7O6S
|
2
|
1 |
IC50 = 490 nM
|
|
|
2 |
IC50 = 680 nM
|
|
|
CP0268306
|
2-{4-[2-(2,4-Diamino-5-methyl-pyrido[2,3-d]pyrimidin-6-yl)-ethyl]-benzoylamino}-pentanedioic acid
Show/Hide
|
C22H24N6O5
|
1
|
1 |
IC50 = 23.2 nM
|
|
|
CP0297780
|
2-{4-[(4-Amino-2-methyl-pteridin-6-ylmethyl)-amino]-benzoylamino}-pentanedioic acid
Show/Hide
|
C20H21N7O5
|
1
|
1 |
IC50 = 130 nM
|
|
|
CP0299568
|
2-[[4-[(2,4-diaminopteridin-6-yl)methylamino]-3-fluorobenzoyl]amino]pentanedioic acid
Show/Hide
|
C30H30ClFN2O5
|
1
|
1 |
EC50 = 1 nM
|
|
|
CP0308127
|
4-[3-Carboxy-1-(1H-tetrazol-5-yl)-propylcarbamoyl]-2-{4-[(2-methyl-4-oxo-4,6,7,8-tetrahydro-3H-cyclopenta[g]quinazolin-6-yl)-prop-2-ynyl-amino]-benzoylamino}-butyric acid
Show/Hide
|
C32H33N9O7
|
2
|
1 |
IC50 = 1300 nM
|
|
|
2 |
IC50 = 1500 nM
|
|
|
CP0326126
|
2-[2-[(4-amino-5,10-dioxonaphtho[2,3-f][1]benzothiol-11-yl)amino]ethyl]guanidine;hydrochloride
Show/Hide
|
C19H18ClN5O2S
|
1
|
1 |
IC50 = 22000 nM
|
|
|
CP0358670
|
2-{4-[(4-Amino-pteridin-6-ylmethyl)-amino]-benzoylamino}-pentanedioic acid
Show/Hide
|
C19H19N7O5
|
3
|
1 |
IC50 = 82 nM
|
|
|
2 |
IC50 = 260 nM
|
|
|
3 |
IC50 > 100000 nM
|
|
|
CP0359177
|
2-(4-Carboxy-4-{4-[(2-methyl-4-oxo-4,6,7,8-tetrahydro-3H-cyclopenta[g]quinazolin-6-yl)-prop-2-ynyl-amino]-benzoylamino}-butyrylamino)-4-(1-carboxymethyl-1H-tetrazol-5-yl)-butyric acid
Show/Hide
|
C34H35N9O9
|
1
|
1 |
IC50 = 7200 nM
|
|
|
CP0372614
|
5-fluoro-1-[(6S)-5-methylidene-2H-pyran-6-yl]pyrimidine-2,4-dione
Show/Hide
|
C10H9FN2O3
|
1
|
1 |
IC50 = 18000 nM
|
|
|
CP0372615
|
1-[(2S,4S,5R)-4,5-dihydroxy-3-methylideneoxan-2-yl]-5-fluoropyrimidine-2,4-dione
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|
C10H11FN2O5
|
4
|
1 |
IC50 = 18000 nM
|
|
|
2 |
IC50 = 21000 nM
|
|
|
3 |
IC50 = 85000 nM
|
|
|
4 |
IC50 > 500000 nM
|
|
|
CP0372616
|
(S)-5-fluoro-4-hydroxy-1-(3-oxo-3,6-dihydro-2H-pyran-2-yl)pyrimidin-2(1H)-one
Show/Hide
|
C9H7FN2O4
|
6
|
1 |
IC50 = 1300 nM
|
|
|
2 |
IC50 = 2500 nM
|
|
|
3 |
IC50 = 3500 nM
|
|
|
4 |
IC50 = 63000 nM
|
|
|
5 |
IC50 = 75000 nM
|
|
|
6 |
IC50 = 294000 nM
|
|
|
CP0373630
|
4-(Adamantan-1-ylcarbamoyl)-2-{4-[(2,4-diamino-pteridin-6-ylmethyl)-amino]-benzoylamino}-butyric acid
Show/Hide
|
C29H35N9O4
|
1
|
1 |
IC50 = 510 nM
|
|
|
CP0377175
|
2-{4-[(2-Amino-4-thioxo-3,4-dihydro-quinazolin-6-ylmethyl)-prop-2-ynyl-amino]-benzoylamino}-pentanedioic acid
Show/Hide
|
C24H23N5O5S
|
1
|
1 |
IC50 = 18000 nM
|
|
|
CP0378540
|
7-tert-butylcarbonyloxy-4-hydroxybenzo[a]pyrrolo[3,4-c]carbazole-1,3(2H,8H)-dione
Show/Hide
|
C23H18N2O5
|
1
|
1 |
IC50 = 1950 nM
|
|
|
CP0378548
|
2-(4-{[(2,4-Diamino-quinazolin-6-yl)-formyl-amino]-methyl}-benzoylamino)-pentanedioic acid
Show/Hide
|
C22H22N6O6
|
1
|
1 |
IC50 > 103000 nM
|
|
|
CP0391320
|
(2S)-2-[[4-[[4-chloro-2-(fluoromethyl)quinolin-6-yl]methyl-prop-2-ynylamino]benzoyl]amino]pentanedioic acid
Show/Hide
|
C26H23ClFN3O5
|
1
|
1 |
IC50 > 100000 nM
|
|
|
CP0394263
|
(2S)-5-[[(1R)-1-carboxyethyl]amino]-2-[[4-[(2-methyl-4-oxo-3,6,7,8-tetrahydrocyclopenta[g]quinazolin-6-yl)-prop-2-ynylamino]benzoyl]amino]-5-oxopentanoic acid
Show/Hide
|
C30H31N5O7
|
1
|
1 |
IC50 = 420 nM
|
|
|
CP0395506
|
2-{4-[(2,4-Diamino-quinazolin-6-ylamino)-methyl]-benzoylamino}-pentanedioic acid
Show/Hide
|
C21H22N6O5
|
1
|
1 |
IC50 = 1500 nM
|
|
|
CP0405929
|
4-(Benzo[1,3]dioxol-5-ylcarbamoyl)-2-{4-[(2,4-diamino-pteridin-6-ylmethyl)-methyl-amino]-benzoylamino}-butyric acid
Show/Hide
|
C27H27N9O6
|
2
|
1 |
IC50 = 2.9 nM
|
|
|
2 |
IC50 = 25000 nM
|
|
|
CP0409799
|
2-{4-[(4-Chloro-2-methyl-quinolin-6-ylmethyl)-prop-2-ynyl-amino]-2-fluoro-benzoylamino}-pentanedioic acid
Show/Hide
|
C26H23ClFN3O5
|
1
|
1 |
IC50 = 420 nM
|
|
|
CP0412551
|
10-Benzyloxy-1H-pyrido[3'4':4,5]pyrrolo[2,3-a]-pyrrolo[3,4-c]carbazole-5,7-(6H,12H)-dione
Show/Hide
|
C26H16N4O3
|
1
|
1 |
IC50 = 1100 nM
|
|
|
CP0424055
|
(2S)-4-[2-(carboxymethyl)tetrazol-5-yl]-2-[[4-[(2-methyl-4-oxo-3,6,7,8-tetrahydrocyclopenta[g]quinazolin-6-yl)-prop-2-ynylamino]benzoyl]amino]butanoic acid
Show/Hide
|
C29H28N8O6
|
2
|
1 |
IC50 = 180 nM
|
|
|
2 |
IC50 = 1300 nM
|
|
|
CP0424299
|
3-(4-Carboxy-4-{4-[(2,4-diamino-pteridin-6-ylmethyl)-methyl-amino]-benzoylamino}-butyrylamino)-benzoic acid
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|
C27H27N9O6
|
1
|
1 |
IC50 = 1.6 nM
|
|
|
CP0426809
|
4-(Benzo[1,3]dioxol-5-ylcarbamoyl)-2-{4-[(2,4-diamino-pteridin-6-ylmethyl)-amino]-benzoylamino}-butyric acid
Show/Hide
|
C26H25N9O6
|
2
|
1 |
IC50 = 0.39 nM
|
|
|
2 |
IC50 = 3.2 nM
|
|
|
CP0427269
|
2-{4-[(4-Chloro-2-methyl-quinolin-6-ylmethyl)-ethyl-amino]-benzoylamino}-pentanedioic acid ; hydrate
Show/Hide
|
C25H26ClN3O5
|
1
|
1 |
IC50 = 23000 nM
|
|
|
CP0429035
|
2-{4-[(2,4-Diamino-pteridin-6-ylmethyl)-amino]-benzoylamino}-3-phosphono-propionic acid
Show/Hide
|
C17H19N8O6P
|
1
|
1 |
IC50 = 390000 nM
|
|
|
CP0430475
|
2-{4-[(2,4-Diamino-pteridin-6-ylmethyl)-amino]-benzoylamino}-4-phosphono-butyric acid
Show/Hide
|
C18H21N8O6P
|
1
|
1 |
IC50 = 67 nM
|
|
|
CP0431009
|
2-{4-[(2,4-Dichloro-quinolin-6-ylmethyl)-prop-2-ynyl-amino]-2-fluoro-benzoylamino}-pentanedioic acid ; hydrate
Show/Hide
|
C25H20Cl2FN3O5
|
1
|
1 |
IC50 = 1000 nM
|
|
|
CP0432445
|
2-{4-[(2,4-Diamino-pteridin-6-ylmethyl)-amino]-benzoylamino}-4-(3,4-dichloro-benzylcarbamoyl)-butyric acid
Show/Hide
|
C26H25Cl2N9O4
|
2
|
1 |
IC50 = 34 nM
|
|
|
2 |
IC50 = 46 nM
|
|
|
CP0434007
|
6-Amino-2-[6-amino-2-(4-carboxy-4-{4-[(2,4-diamino-pteridin-6-ylmethyl)-methyl-amino]-benzoylamino}-butyrylamino)-hexanoylamino]-hexanoic acid
Show/Hide
|
C32H46N12O7
|
1
|
1 |
IC50 = 1800 nM
|
|
|
CP0434649
|
2-{4-[(2,4-Diamino-quinazolin-6-ylmethyl)-methyl-amino]-benzoylamino}-pentanedioic acid
Show/Hide
|
C22H24N6O5
|
1
|
1 |
IC50 = 17 nM
|
|
|
CP0435748
|
10-Hydroxy-1H-pyrido[3'4':4,5]pyrrolo[2,3-a]pyrrolo[3,4-c]carbazole-5,7-(6H,12H)-dione
Show/Hide
|
C19H10N4O3
|
1
|
1 |
IC50 = 3300 nM
|
|
|
CP0436458
|
1H-pyrido[3'4':4,5]pyrrolo[2,3-a]pyrrolo[3,4-c]-carbazole-5,7-(6H,12H)-dione
Show/Hide
|
C19H10N4O2
|
1
|
1 |
IC50 = 600 nM
|
|
|
CP0437651
|
2-{4-[(2,4-Diamino-pteridin-6-ylmethyl)-amino]-benzoylamino}-4-(2,6-dichloro-benzylcarbamoyl)-butyric acid
Show/Hide
|
C26H25Cl2N9O4
|
3
|
1 |
IC50 = 2 nM
|
|
|
2 |
IC50 = 3.7 nM
|
|
|
3 |
IC50 = 61000 nM
|
|
|
CP0437855
|
2-{4-[(4-Chloro-2-trifluoromethyl-quinolin-6-ylmethyl)-prop-2-ynyl-amino]-benzoylamino}-pentanedioic acid ; hydrate
Show/Hide
|
C26H21ClF3N3O5
|
1
|
1 |
IC50 > 100000 nM
|
|
|
CP0440214
|
2-{4-[(2-Carbamoyl-4-chloro-quinolin-6-ylmethyl)-prop-2-ynyl-amino]-benzoylamino}-pentanedioic acid ; hydrate
Show/Hide
|
C26H23ClN4O6
|
1
|
1 |
IC50 > 100000 nM
|
|
|
CP0440223
|
2-{4-[(4-Cyano-2-methyl-quinolin-6-ylmethyl)-prop-2-ynyl-amino]-benzoylamino}-pentanedioic acid ; hydrate
Show/Hide
|
C27H24N4O5
|
1
|
1 |
IC50 = 75000 nM
|
|
|
CP0441711
|
2-{4-[(4-Chloro-2-methyl-quinolin-6-ylmethyl)-amino]-benzoylamino}-pentanedioic acid ; hydrate
Show/Hide
|
C23H22ClN3O5
|
1
|
1 |
IC50 > 100000 nM
|
|
|
CP0444084
|
2-{4-[(2-Amino-4-methyl-quinolin-6-ylmethyl)-prop-2-ynyl-amino]-benzoylamino}-pentanedioic acid ; hydrate
Show/Hide
|
C26H26N4O5
|
1
|
1 |
IC50 = 4000 nM
|
|
|
CP0448244
|
2-{4-[(2,4-Diamino-pteridin-6-ylmethyl)-prop-2-ynyl-amino]-benzoylamino}-pentanedioic acid
Show/Hide
|
C22H22N8O5
|
1
|
1 |
IC50 = 1.4 nM
|
|
|
CP0448989
|
(S)-4-((S)-1-Carboxy-ethylcarbamoyl)-2-{4-[(2-methyl-4-oxo-3,4-dihydro-quinazolin-6-ylmethyl)-prop-2-ynyl-amino]-benzoylamino}-butyric acid
Show/Hide
|
C28H29N5O7
|
2
|
1 |
IC50 = 620 nM
|
|
|
2 |
IC50 = 790 nM
|
|
|
CP0453077
|
2-{4-[1-(2,4-Diamino-pyrido[2,3-d]pyrimidin-6-ylmethyl)-propyl]-benzoylamino}-pentanedioic acid
Show/Hide
|
C23H26N6O5
|
1
|
1 |
IC50 = 12.1 nM
|
|
|
CP0453649
|
2-{4-[(2,4-Dimethyl-quinolin-6-ylmethyl)-prop-2-ynyl-amino]-benzoylamino}-pentanedioic acid ; hydrate
Show/Hide
|
C27H27N3O5
|
1
|
1 |
IC50 > 100000 nM
|
|
|
CP0454354
|
4-tert-Butylcarbamoyl-2-{4-[(2,4-diamino-pteridin-6-ylmethyl)-amino]-benzoylamino}-butyric acid
Show/Hide
|
C23H29N9O4
|
2
|
1 |
IC50 = 120 nM
|
|
|
2 |
IC50 = 22000 nM
|
|
|
CP0454692
|
2-{4-[(2,4-Diamino-pteridin-6-ylmethyl)-methyl-amino]-benzoylamino}-3-ureido-propionic acid
Show/Hide
|
C19H22N10O4
|
1
|
1 |
IC50 = 9.4 nM
|
|
|
CP0457476
|
9-Benzyloxy-1H-pyrido[3'4':4,5]pyrrolo[2,3-a]pyrrolo[3,4-c]carbazole-5,7(6H,12H)-dione
Show/Hide
|
C26H16N4O3
|
1
|
1 |
IC50 = 1500 nM
|
|
|
CP0458868
|
5-(2-Chloro-acetylamino)-2-{4-[(2,4-diamino-pteridin-6-ylmethyl)-methyl-amino]-benzoylamino}-pentanoic acid
Show/Hide
|
C22H26ClN9O4
|
1
|
1 |
IC50 = 105 nM
|
|
|
CP0460781
|
2-{4-[(4-Chloro-2-methyl-quinolin-6-ylmethyl)-methyl-amino]-benzoylamino}-pentanedioic acid ; hydrate
Show/Hide
|
C24H24ClN3O5
|
1
|
1 |
IC50 = 24000 nM
|
|
|
CP0462832
|
2-{4-[(2-Chloro-4-methyl-quinolin-6-ylmethyl)-prop-2-ynyl-amino]-benzoylamino}-pentanedioic acid ; hydrate
Show/Hide
|
C26H24ClN3O5
|
1
|
1 |
IC50 > 100000 nM
|
|
|
CP0463413
|
2-{4-[1-(2-Amino-4-hydroxy-5,6,7,8-tetrahydro-pyrido[2,3-d]pyrimidin-6-ylmethyl)-propyl]-benzoylamino}-pentanedioic acid
Show/Hide
|
C23H29N5O6
|
1
|
1 |
IC50 = 34.6 nM
|
|
|
CP0475992
|
6-(2-Bromo-acetylamino)-2-{4-[(2,4-diamino-pteridin-6-ylmethyl)-methyl-amino]-benzoylamino}-hexanoic acid
Show/Hide
|
C23H28BrN9O4
|
1
|
1 |
IC50 = 0.096 nM
|
|
|
CP0480410
|
2-({4-[(2,4-Diamino-pyrido[2,3-d]pyrimidin-6-ylmethyl)-amino]-5,6,7,8-tetrahydro-naphthalene-1-carbonyl}-amino)-pentanedioic acid
Show/Hide
|
C24H27N7O5
|
1
|
1 |
IC50 = 16 nM
|
|
|
CP0483239
|
2-{4-[Ethyl-(4-thioxo-3,4-dihydro-quinazolin-6-ylmethyl)-amino]-benzoylamino}-pentanedioic acid
Show/Hide
|
C23H24N4O5S
|
1
|
1 |
IC50 = 31000 nM
|
|
|
CP0493425
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2-[4-(1,3-Diamino-7,8,9,10-tetrahydro-pyrimido[4,5-c]isoquinolin-8-yl)-benzoylamino]-pentanedioic acid
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C23H24N6O5
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1
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1 |
IC50 = 4.5 nM
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CP0493566
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2-{4-[(2,4-Dichloro-quinolin-6-ylmethyl)-prop-2-ynyl-amino]-benzoylamino}-pentanedioic acid ; hydrate
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C25H21Cl2N3O5
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1
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1 |
IC50 = 8000 nM
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CP0497674
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2-{4-[(2-Methyl-4-thioxo-3,4-dihydro-quinazolin-6-ylmethyl)-prop-2-ynyl-amino]-benzoylamino}-pentanedioic acid
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C25H24N4O5S
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1
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1 |
IC50 = 8000 nM
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CP0502292
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2-{4-[(4-Methoxy-2-methyl-quinolin-6-ylmethyl)-prop-2-ynyl-amino]-benzoylamino}-pentanedioic acid ; hydrate
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C27H27N3O6
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1
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1 |
IC50 > 100000 nM
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CP0502698
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2-{4-[(4-Chloro-2-methoxy-quinolin-6-ylmethyl)-prop-2-ynyl-amino]-benzoylamino}-pentanedioic acid ; hydrate
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C26H24ClN3O6
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1
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1 |
IC50 > 100000 nM
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CP0505526
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2-{4-[(4-Bromo-2-methyl-quinolin-6-ylmethyl)-prop-2-ynyl-amino]-benzoylamino}-pentanedioic acid ; hydrate
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C26H24BrN3O5
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1
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1 |
IC50 = 14000 nM
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CP0505693
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2-{4-[(2,4-Diamino-pteridin-6-ylmethyl)-amino]-benzoylamino}-5-phosphono-pentanoic acid
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C19H23N8O6P
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1
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1 |
IC50 = 120 nM
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CP0511400
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(S)-4-((S)-1-Carboxy-2-phenyl-ethylcarbamoyl)-2-{4-[(2-methyl-4-oxo-3,4-dihydro-quinazolin-6-ylmethyl)-prop-2-ynyl-amino]-benzoylamino}-butyric acid
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C34H33N5O7
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1
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1 |
IC50 = 4400 nM
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CP0514256
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2-{4-[(2,4-Diamino-pteridin-6-ylmethyl)-methyl-amino]-benzoylamino}-4-(3,4-dihydroxy-phenylcarbamoyl)-butyric acid
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C26H27N9O6
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1
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1 |
IC50 = 38000 nM
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CP0515183
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2-[2-[[11-[2-(methylamino)ethylamino]-5,10-dioxonaphtho[2,3-f][1]benzothiol-4-yl]amino]ethyl]guanidine;hydrochloride
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C22H25ClN6O2S
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1
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1 |
IC50 = 23000 nM
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CP0518169
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5-(2-Bromo-acetylamino)-2-{4-[(2,4-diamino-pteridin-6-ylmethyl)-methyl-amino]-benzoylamino}-pentanoic acid
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C22H26BrN9O4
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1
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1 |
IC50 = 0.126 nM
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CP0523970
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(2S)-4-[1-(3-carboxypropyl)tetrazol-5-yl]-2-[[4-[(2-methyl-4-oxo-3,6,7,8-tetrahydrocyclopenta[g]quinazolin-6-yl)-prop-2-ynylamino]benzoyl]amino]butanoic acid
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C31H32N8O6
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1
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1 |
IC50 = 2700 nM
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CP0525400
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3-(4-Carboxy-4-{4-[(2,4-diamino-pteridin-6-ylmethyl)-methyl-amino]-benzoylamino}-butyrylamino)-benzene m-boronalide(methotrexate gama-(m-boronalide))
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C26H28BN9O6
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1
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1 |
IC50 = 0.7 nM
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CP0527642
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2-{4-[(4-Chloro-2-hydroxymethyl-quinolin-6-ylmethyl)-ethyl-amino]-benzoylamino}-pentanedioic acid ; hydrate
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C25H26ClN3O6
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1
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1 |
IC50 > 100000 nM
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CP0528439
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9-Hydroxy-1H-pyrido[3'4':4,5]pyrrolo[2,3-a]pyrrolo[3,4-c]carbazole-5,7-(6H,12H)-dione
Show/Hide
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C19H10N4O3
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1
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1 |
IC50 = 80700 nM
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CP0529728
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4-hydroxy-11-methyl-7-hydroxysulfonyloxybenzo[a]pyrrolo-[3,4-c]carbazole-1,3(2H,8H)-dione
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C19H12N2O7S
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1
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1 |
IC50 = 25600 nM
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CP0529872
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2-{4-[(2,4-Diamino-pteridin-6-ylmethyl)-amino]-benzoylamino}-6-phosphono-hexanoic acid
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C20H25N8O6P
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1
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1 |
IC50 = 130 nM
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CP0532708
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2--[3-(2-Carboxy-2-{4-[(2,4-diamino-pteridin-6-ylmethyl)-methyl-amino]-benzoylamino}-ethylchloro) -n-nitraso]-ethyl ester
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C23H28ClN11O5
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1
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1 |
IC50 = 2900 nM
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CP0535593
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2-{4-[(2,4-Diamino-pteridin-6-ylmethyl)-amino]-benzoylamino}-4-phenylcarbamoyl-butyric acid
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C25H25N9O4
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3
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1 |
IC50 = 3.5 nM
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2 |
IC50 = 3.6 nM
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3 |
IC50 = 10000 nM
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CP0535758
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2-{4-[(4-Hydroxy-2-methyl-quinolin-6-ylmethyl)-prop-2-ynyl-amino]-benzoylamino}-pentanedioic acid ; hydrate
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C26H25N3O6
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1
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1 |
IC50 > 100000 nM
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CP0543962
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; hydrate2-{4-[(2-Methyl-4-methylsulfanyl-quinolin-6-ylmethyl)-prop-2-ynyl-amino]-benzoylamino}-pentanedioic acid ; hydrate
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C27H27N3O5S
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1
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1 |
IC50 = 100000 nM
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CP0545267
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(2R)-2-[[(4S)-4-carboxy-4-[[4-[(2-methyl-4-oxo-3,6,7,8-tetrahydrocyclopenta[g]quinazolin-6-yl)-prop-2-ynylamino]benzoyl]amino]butanoyl]-methylamino]pentanedioic acid
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C33H35N5O9
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1
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1 |
IC50 = 2300 nM
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CP0553495
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N'-[2-[[11-[2-(1-aminoethylideneamino)ethylamino]-5,10-dioxonaphtho[2,3-f][1]benzothiol-4-yl]amino]ethyl]ethanimidamide;hydrochloride
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C24H27ClN6O2S
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1
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1 |
IC50 = 36000 nM
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CP0565389
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(2S)-4-[1-(carboxymethyl)tetrazol-5-yl]-2-[[4-[(2-methyl-4-oxo-3,6,7,8-tetrahydrocyclopenta[g]quinazolin-6-yl)-prop-2-ynylamino]benzoyl]amino]butanoic acid
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C29H28N8O6
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1
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1 |
IC50 = 4100 nM
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CP0573415
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2-{4-[(2,4-Diamino-pteridin-6-ylmethyl)-methyl-amino]-benzoylamino}-3-(3-methyl-ureido)-propionic acid
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C20H24N10O4
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1
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1 |
IC50 = 34.3 nM
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CP0719695
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(R)-2-((S)-4-Carboxy-4-{4-[(2,7-dimethyl-4-oxo-3,4-dihydro-quinazolin-6-ylmethyl)-prop-2-ynyl-amino]-2-fluoro-benzoylamino}-butyrylamino)-hexanedioic acid TFA
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C34H35F4N5O11
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1
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1 |
IC50 = 130 nM
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CP0786904
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2-{2-Fluoro-4-[(2-methyl-4-oxo-3,4-dihydro-quinazolin-6-ylmethyl)-prop-2-ynyl-amino]-benzoylamino}-pentanedioic acid hydrate
Show/Hide
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C25H23FN4O6
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1
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1 |
IC50 = 27 nM
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CP0847326
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2-{2,3-Difluoro-4-[(2-methyl-4-oxo-3,4-dihydro-quinazolin-6-ylmethyl)-prop-2-ynyl-amino]-benzoylamino}-pentanedioic acid ;hydrate (2H2O)
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C25H22F2N4O6
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1
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1 |
IC50 = 280 nM
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CP0869934
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6-[(3,4,5-Trimethoxy-phenylamino)-methyl]-3H-quinazolin-4-one
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C18H19N3O4
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1
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1 |
IC50 > 10000 nM
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CP0897235
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(R)-2-((S)-4-Carboxy-4-{4-[methyl-(2-methyl-4-oxo-3,4-dihydro-quinazolin-6-ylmethyl)-amino]-benzoylamino}-butyrylamino)-pentanedioic acid TFA
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C30H32F3N5O11
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1
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1 |
IC50 = 3200 nM
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CP0899706
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2-{2,5-Difluoro-4-[methyl-(2-methyl-4-oxo-3,4-dihydro-quinazolin-6-ylmethyl)-amino]-benzoylamino}-pentanedioic acid ;hydrate (H2O)
Show/Hide
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C23H22F2N4O6
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1
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1 |
IC50 = 75 nM
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CP0902152
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SID536072
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C25H28ClFN3O9P
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2
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1 |
IC50 = 0.63 nM
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2 |
IC50 = 16 nM
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CP0903163
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2-{4-[(2-Acetylamino-4-chloro-quinolin-6-ylmethyl)-prop-2-ynyl-amino]-benzoylamino}-pentanedioic acid TFA with hydrate
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C29H26ClF3N4O8
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1
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1 |
IC50 > 100000 nM
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CP0916072
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2-{2,6-Difluoro-4-[(2-methyl-4-oxo-3,4-dihydro-quinazolin-6-ylmethyl)-prop-2-ynyl-amino]-benzoylamino}-pentanedioic acid hydrate (H2O)
Show/Hide
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C25H22F2N4O6
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1
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1 |
IC50 = 62 nM
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CP0920687
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(R)-2-((S)-4-Carboxy-4-{2-fluoro-4-[(2-methyl-4-oxo-3,4-dihydro-quinazolin-6-ylmethyl)-prop-2-ynyl-amino]-benzoylamino}-butyrylamino)-pentanedioic acid TFA
Show/Hide
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C32H31F4N5O11
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1
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1 |
IC50 = 210 nM
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CP0945051
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(R)-2-((S)-4-Carboxy-4-{2-fluoro-4-[methyl-(2-methyl-4-oxo-3,4-dihydro-quinazolin-6-ylmethyl)-amino]-benzoylamino}-butyrylamino)-pentanedioic acid TFA
Show/Hide
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C30H31F4N5O11
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1
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1 |
IC50 = 650 nM
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CP0947325
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2-{2,6-Difluoro-4-[methyl-(2-methyl-4-oxo-3,4-dihydro-quinazolin-6-ylmethyl)-amino]-benzoylamino}-pentanedioic acid ;hydrate (1.25H2O)
Show/Hide
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C23H22F2N4O6
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1
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1 |
IC50 = 50 nM
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