Brief Information of the Compound and Protein
Compound Name
4-(Benzo[1,3]dioxol-5-ylcarbamoyl)-2-{4-[(2,4-diamino-pteridin-6-ylmethyl)-amino]-benzoylamino}-butyric acid
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PubChem ID
CID: 44292274
Canonical SMILES
Nc1nc(N)c2nc(CNc3ccc(cc3)C(=O)NC(CCC(=O)Nc3ccc4OCOc4c3)C(O)=O)cnc2n1
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Compound Formula C26H25N9O6
Compound Structure
Protein Name
Dihydrofolate reductase
Protein Classification
Enzyme
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Oxidoreductase
Uniprot ID
P00375
Gene Name
DHFR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000266 L1210 Mus musculus (Mouse)  1
1
IC50 = 45 nM
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