Brief Information of the Compound and Protein
Compound Name
(6RS) 2-{4-[2-(2-Amino-5-ethyl-4-oxo-3,4,5,6,7,8-hexahydro-pyrido[2,3-d]pyrimidin-6-yl)-ethyl]-benzoylamino}-pentanedioic acid
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PubChem ID
CID: 136044127
Canonical SMILES
CCC1C(CCc2ccc(cc2)C(=O)NC(CCC(O)=O)C(O)=O)CNc2nc(N)[nH]c(=O)c12
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Compound Formula C23H29N5O6
Compound Structure
Protein Name
Dihydrofolate reductase
Protein Classification
Enzyme
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Oxidoreductase
Uniprot ID
P00375
Gene Name
DHFR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000266 L1210 Mus musculus (Mouse)  1
1
Ki > 1 nM
   TI
   LI
   LO
   TS