| Compound ID |
Compound Name |
Compound Formula |
|
CP0114441
|
2-[[2-[3-(2-fluoroethoxy)-4-methoxyphenyl]-5-propyl-1,3-thiazol-4-yl]methylsulfanyl]pyrimidine-4,6-diamine
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|
C20H24FN5O2S2
|
1
|
| 1 |
IC50 = 3 nM
|
|
|
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CP0524790
|
2-[[5-ethyl-2-[3-(2-fluoroethoxy)-4-methoxyphenyl]-1,3-thiazol-4-yl]methylsulfanyl]pyrimidine-4,6-diamine
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|
C19H22FN5O2S2
|
1
|
| 1 |
IC50 = 30 nM
|
|
|
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CP0144043
|
2-[[2-[3-(2-fluoroethoxy)-4-methoxyphenyl]-5-methyl-1,3-thiazol-4-yl]methylsulfanyl]pyrimidine-4,6-diamine
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|
C18H20FN5O2S2
|
1
|
| 1 |
IC50 = 35 nM
|
|
|
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CP0515354
|
2-[[2-(4-fluorophenyl)-5-propyl-1,3-thiazol-4-yl]methylsulfanyl]pyrimidine-4,6-diamine
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|
C17H18FN5S2
|
1
|
| 1 |
IC50 = 170 nM
|
|
|
|
CP0396011
|
2-[[2-(3-fluorophenyl)-5-propyl-1,3-thiazol-4-yl]methylsulfanyl]pyrimidine-4,6-diamine
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|
C17H18FN5S2
|
1
|
| 1 |
IC50 = 175 nM
|
|
|
|
CP0375253
|
2-[[2-(3-fluorophenyl)-5-methyl-1,3-thiazol-4-yl]methylsulfanyl]pyrimidine-4,6-diamine
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|
C15H14FN5S2
|
1
|
| 1 |
IC50 = 255 nM
|
|
|
|
CP0385614
|
2-[[5-ethyl-2-(4-fluorophenyl)-1,3-thiazol-4-yl]methylsulfanyl]pyrimidine-4,6-diamine
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|
C16H16FN5S2
|
1
|
| 1 |
IC50 = 265 nM
|
|
|
|
CP0392032
|
2-[[2-[3-(3-fluoropropoxy)-4-methoxyphenyl]-1,3-thiazol-4-yl]methylsulfanyl]pyrimidine-4,6-diamine
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|
C18H20FN5O2S2
|
1
|
| 1 |
IC50 = 330 nM
|
|
|
|
CP0505043
|
2-[[2-(3,5-difluorophenyl)-5-propyl-1,3-thiazol-4-yl]methylsulfanyl]pyrimidine-4,6-diamine
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|
C17H17F2N5S2
|
1
|
| 1 |
IC50 = 385 nM
|
|
|
|
CP0524139
|
2-[[2-(4-fluorophenyl)-5-methyl-1,3-thiazol-4-yl]methylsulfanyl]pyrimidine-4,6-diamine
Show/Hide
|
C15H14FN5S2
|
1
|
| 1 |
IC50 = 395 nM
|
|
|
|
CP0524137
|
2-[[5-ethyl-2-(3-fluorophenyl)-1,3-thiazol-4-yl]methylsulfanyl]pyrimidine-4,6-diamine
Show/Hide
|
C16H16FN5S2
|
1
|
| 1 |
IC50 = 510 nM
|
|
|
|
CP0392034
|
2-[[2-[4-ethoxy-3-(2-fluoroethoxy)phenyl]-1,3-thiazol-4-yl]methylsulfanyl]pyrimidine-4,6-diamine
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|
C18H20FN5O2S2
|
1
|
| 1 |
IC50 = 513 nM
|
|
|
|
CP0447080
|
6-[[2-[3-(2-fluoroethoxy)-4-methoxyphenyl]-1,3-thiazol-4-yl]methylsulfanyl]-1,3,5-triazine-2,4-diamine
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|
C16H17FN6O2S2
|
1
|
| 1 |
IC50 = 528 nM
|
|
|
|
CP0432324
|
2-[[2-[3-(2-fluoroethoxy)-4-methoxyphenyl]-1,3-thiazol-4-yl]methylsulfanyl]pyrimidine-4,6-diamine
Show/Hide
|
C17H18FN5O2S2
|
1
|
| 1 |
IC50 = 538 nM
|
|
|
|
CP0426769
|
2-[[2-(3,5-difluorophenyl)-5-methyl-1,3-thiazol-4-yl]methylsulfanyl]pyrimidine-4,6-diamine
Show/Hide
|
C15H13F2N5S2
|
1
|
| 1 |
IC50 = 595 nM
|
|
|
|
CP0375252
|
6-[[2-[3-(3-fluoropropoxy)-4-methoxyphenyl]-1,3-thiazol-4-yl]methylsulfanyl]-1,3,5-triazine-2,4-diamine
Show/Hide
|
C17H19FN6O2S2
|
1
|
| 1 |
IC50 = 603 nM
|
|
|
|
CP0538953
|
2-[[2-(3,5-difluorophenyl)-5-ethyl-1,3-thiazol-4-yl]methylsulfanyl]pyrimidine-4,6-diamine
Show/Hide
|
C16H15F2N5S2
|
1
|
| 1 |
IC50 = 620 nM
|
|
|
|
CP0544884
|
2-[[2-[4-(2-fluoroethoxy)-3-methoxyphenyl]-1,3-thiazol-4-yl]methylsulfanyl]pyrimidine-4,6-diamine
Show/Hide
|
C17H18FN5O2S2
|
1
|
| 1 |
IC50 = 808 nM
|
|
|
|
CP0524140
|
2-[[2-(4-ethoxy-3-methoxyphenyl)-1,3-thiazol-4-yl]methylsulfanyl]pyrimidine-4,6-diamine
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|
C17H19N5O2S2
|
1
|
| 1 |
IC50 = 1120 nM
|
|
|
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CP0524138
|
6-[[2-[4-ethoxy-3-(2-fluoroethoxy)phenyl]-1,3-thiazol-4-yl]methylsulfanyl]-1,3,5-triazine-2,4-diamine
Show/Hide
|
C17H19FN6O2S2
|
1
|
| 1 |
IC50 = 1226 nM
|
|
|
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CP0397095
|
2-[[2-[5-(2-fluoroethoxy)-2-methoxyphenyl]-1,3-thiazol-4-yl]methylsulfanyl]pyrimidine-4,6-diamine
Show/Hide
|
C17H18FN5O2S2
|
1
|
| 1 |
IC50 = 1445 nM
|
|
|
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CP0538954
|
6-[[2-[4-(2-fluoroethoxy)-3-methoxyphenyl]-1,3-thiazol-4-yl]methylsulfanyl]-1,3,5-triazine-2,4-diamine
Show/Hide
|
C16H17FN6O2S2
|
1
|
| 1 |
IC50 = 1612 nM
|
|
|
|
CP0544886
|
2-[[2-(3-methoxyphenyl)-1,3-thiazol-4-yl]methylsulfanyl]pyrimidine-4,6-diamine
Show/Hide
|
C15H15N5OS2
|
1
|
| 1 |
IC50 = 1670 nM
|
|
|
|
CP0540623
|
2-[[2-(5-bromo-2-methoxyphenyl)-1,3-thiazol-4-yl]methylsulfanyl]pyrimidine-4,6-diamine
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|
C15H14BrN5OS2
|
1
|
| 1 |
IC50 = 1760 nM
|
|
|
|
CP0396012
|
2-[[2-(4-methoxyphenyl)-1,3-thiazol-4-yl]methylsulfanyl]pyrimidine-4,6-diamine
Show/Hide
|
C15H15N5OS2
|
1
|
| 1 |
IC50 = 2020 nM
|
|
|
|
CP0540624
|
2-[[2-(4-methylphenyl)-1,3-thiazol-4-yl]methylsulfanyl]pyrimidine-4,6-diamine
Show/Hide
|
C15H15N5S2
|
1
|
| 1 |
IC50 = 2320 nM
|
|
|
|
CP0515355
|
2-[[2-[3-(2-fluoroethoxy)-4-methylphenyl]-1,3-thiazol-4-yl]methylsulfanyl]pyrimidine-4,6-diamine
Show/Hide
|
C17H18FN5OS2
|
1
|
| 1 |
IC50 = 2381 nM
|
|
|
|
CP0420297
|
6-[[2-[5-(2-fluoroethoxy)-2-methoxyphenyl]-1,3-thiazol-4-yl]methylsulfanyl]-1,3,5-triazine-2,4-diamine
Show/Hide
|
C16H17FN6O2S2
|
1
|
| 1 |
IC50 = 2649 nM
|
|
|
|
CP0524991
|
6-[[2-[3-(2-fluoroethoxy)-4-methylphenyl]-1,3-thiazol-4-yl]methylsulfanyl]-1,3,5-triazine-2,4-diamine
Show/Hide
|
C16H17FN6OS2
|
1
|
| 1 |
IC50 = 3201 nM
|
|
|
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CP0526565
|
2-[[2-[4-(2-fluoroethoxy)-2-methoxyphenyl]-1,3-thiazol-4-yl]methylsulfanyl]pyrimidine-4,6-diamine
Show/Hide
|
C17H18FN5O2S2
|
1
|
| 1 |
IC50 = 5469 nM
|
|
|
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CP0524141
|
2-(4-methoxyphenyl)-4-(pyrimidin-2-ylsulfanylmethyl)-1,3-thiazole
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|
C15H13N3OS2
|
1
|
| 1 |
IC50 > 100000 nM
|
|
|
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CP0526566
|
2-phenyl-4-(pyrimidin-2-ylsulfanylmethyl)-1,3-thiazole
Show/Hide
|
C14H11N3S2
|
1
|
| 1 |
IC50 > 100000 nM
|
|
|
