Brief Information of the Cell Line and Protein
Cell Line ID: CL000266 , L1210
Synonyms
L 1210
L-1210
Leukemic 1210
Leukemia 1210
Leukemia L1210
Category Cancer cell line
Organism
Mus musculus (Mouse)
Cellosaurus ID
CVCL_0382
Protein ID: PT01883 , Thymidylate synthase
Gene Name TYMS
Organism Mus musculus, Mouse
Protein Classification Enzyme
Uniprot ID P07607
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000266  Protein ID: PT01883
 
Compound ID Compound Name Compound Formula
CP0683934
(R)-2-((S)-4-Carboxy-4-{4-[(2,7-dimethyl-4-oxo-3,4-dihydro-quinazolin-6-ylmethyl)-prop-2-ynyl-amino]-2-fluoro-benzoylamino}-butyrylamino)-pentanedioic acid TFA
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C33H33F4N5O11
 1
1
IC50 = 0.4 nM
   TI
   LI
   LO
   TS
CP0077456
1-(beta-D-2-deoxy-erythro-pentofuranosyl)-5-fluorouracil
   Show/Hide
C9H11FN2O5
 3
1
IC50 = 0.4 nM
   TI
   LI
   LO
   TS
2
IC50 = 0.6 nM
   TI
   LI
   LO
   TS
3
IC50 = 0.7 nM
   TI
   LI
   LO
   TS
CP0719695
(R)-2-((S)-4-Carboxy-4-{4-[(2,7-dimethyl-4-oxo-3,4-dihydro-quinazolin-6-ylmethyl)-prop-2-ynyl-amino]-2-fluoro-benzoylamino}-butyrylamino)-hexanedioic acid TFA
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C34H35F4N5O11
 1
1
IC50 = 0.56 nM
   TI
   LI
   LO
   TS
CP0914242
(R)-2-((S)-4-Carboxy-4-{4-[(2,7-dimethyl-4-oxo-3,4-dihydro-quinazolin-6-ylmethyl)-prop-2-ynyl-amino]-benzoylamino}-butyrylamino)-pentanedioic acid TFA
   Show/Hide
C33H34F3N5O11
 1
1
IC50 = 1.9 nM
   TI
   LI
   LO
   TS
CP0920687
(R)-2-((S)-4-Carboxy-4-{2-fluoro-4-[(2-methyl-4-oxo-3,4-dihydro-quinazolin-6-ylmethyl)-prop-2-ynyl-amino]-benzoylamino}-butyrylamino)-pentanedioic acid TFA
   Show/Hide
C32H31F4N5O11
 1
1
IC50 = 1.9 nM
   TI
   LI
   LO
   TS
CP0412173
(S)-2-((S)-4-Carboxy-4-{4-[(2-methyl-4-oxo-3,4-dihydro-quinazolin-6-ylmethyl)-prop-2-ynyl-amino]-benzoylamino}-butyrylamino)-pentanedioic acid
   Show/Hide
C30H31N5O9
 1
1
IC50 = 2 nM
   TI
   LI
   LO
   TS
CP0453122
(S)-2-((S)-4-Carboxy-4-{4-[(2-methyl-4-oxo-3,4-dihydro-quinazolin-6-ylmethyl)-prop-2-ynyl-amino]-benzoylamino}-butyrylamino)-hexanedioic acid
   Show/Hide
C31H33N5O9
 1
1
IC50 = 2 nM
   TI
   LI
   LO
   TS
CP0847562
(R)-2-((S)-4-Carboxy-4-{4-[(2,7-dimethyl-4-oxo-3,4-dihydro-quinazolin-6-ylmethyl)-methyl-amino]-2-fluoro-benzoylamino}-butyrylamino)-pentanedioic acid TFA
   Show/Hide
C31H33F4N5O11
 1
1
IC50 = 2 nM
   TI
   LI
   LO
   TS
CP0861557
(R)-2-((S)-4-Carboxy-4-{4-[(2-methyl-4-oxo-3,4-dihydro-quinazolin-6-ylmethyl)-prop-2-ynyl-amino]-benzoylamino}-butyrylamino)-pentanedioic acid TFA
   Show/Hide
C32H32F3N5O11
 1
1
IC50 = 4.6 nM
   TI
   LI
   LO
   TS
CP0900296
(R)-2-((S)-4-Carboxy-4-{4-[(2,7-dimethyl-4-oxo-3,4-dihydro-quinazolin-6-ylmethyl)-methyl-amino]-benzoylamino}-butyrylamino)-pentanedioic acid TFA
   Show/Hide
C31H34F3N5O11
 1
1
IC50 = 4.6 nM
   TI
   LI
   LO
   TS
CP0945051
(R)-2-((S)-4-Carboxy-4-{2-fluoro-4-[methyl-(2-methyl-4-oxo-3,4-dihydro-quinazolin-6-ylmethyl)-amino]-benzoylamino}-butyrylamino)-pentanedioic acid TFA
   Show/Hide
C30H31F4N5O11
 1
1
IC50 = 8.8 nM
   TI
   LI
   LO
   TS
CP0880586
(S)-4-((R)-1-Carboxy-ethylcarbamoyl)-2-{4-[(2-methyl-4-oxo-3,4-dihydro-quinazolin-6-ylmethyl)-prop-2-ynyl-amino]-benzoylamino}-butyric acid TFA
   Show/Hide
C30H30F3N5O9
 1
1
IC50 = 12 nM
   TI
   LI
   LO
   TS
CP0448989
(S)-4-((S)-1-Carboxy-ethylcarbamoyl)-2-{4-[(2-methyl-4-oxo-3,4-dihydro-quinazolin-6-ylmethyl)-prop-2-ynyl-amino]-benzoylamino}-butyric acid
   Show/Hide
C28H29N5O7
 1
1
IC50 = 13 nM
   TI
   LI
   LO
   TS
CP0039203
US9422297, PDDF
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C24H23N5O6
 2
1
IC50 = 14 nM
   TI
   LI
   LO
   TS
2
Ki = 20 nM
   TI
   LI
   LO
   TS
CP0916088
(R)-2-((S)-4-Carboxy-4-{4-[ethyl-(2-methyl-4-oxo-3,4-dihydro-quinazolin-6-ylmethyl)-amino]-benzoylamino}-butyrylamino)-pentanedioic acid TFA
   Show/Hide
C31H34F3N5O11
 1
1
IC50 = 17 nM
   TI
   LI
   LO
   TS
CP0511400
(S)-4-((S)-1-Carboxy-2-phenyl-ethylcarbamoyl)-2-{4-[(2-methyl-4-oxo-3,4-dihydro-quinazolin-6-ylmethyl)-prop-2-ynyl-amino]-benzoylamino}-butyric acid
   Show/Hide
C34H33N5O7
 1
1
IC50 = 18 nM
   TI
   LI
   LO
   TS
CP0786904
2-{2-Fluoro-4-[(2-methyl-4-oxo-3,4-dihydro-quinazolin-6-ylmethyl)-prop-2-ynyl-amino]-benzoylamino}-pentanedioic acid hydrate
   Show/Hide
C25H23FN4O6
 1
1
IC50 = 20 nM
   TI
   LI
   LO
   TS
CP0046656
(2S)-2-[(4-{[(2-amino-4-oxo-1,4-dihydroquinazolin-6-yl)methyl](prop-2-yn-1-yl)amino}phenyl)formamido]pentanedioic acid
   Show/Hide
C24H23N5O6
 1
1
IC50 = 20 nM
   TI
   LI
   LO
   TS
CP0014938
(5-fluorouracil)5-Fluoro-1H-pyrimidine-2,4-dione
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C4H3FN2O2
 6
1
IC50 = 20 nM
   TI
   LI
   LO
   TS
2
IC50 = 60 nM
   TI
   LI
   LO
   TS
3
IC50 = 220 nM
   TI
   LI
   LO
   TS
4
IC50 = 600 nM
   TI
   LI
   LO
   TS
5
IC50 = 7000 nM
   TI
   LI
   LO
   TS
6
IC50 >= 10000 nM
   TI
   LI
   LO
   TS
CP0431009
2-{4-[(2,4-Dichloro-quinolin-6-ylmethyl)-prop-2-ynyl-amino]-2-fluoro-benzoylamino}-pentanedioic acid ; hydrate
   Show/Hide
C25H20Cl2FN3O5
 1
1
IC50 = 23 nM
   TI
   LI
   LO
   TS
CP0895064
(R)-2-((R)-4-Carboxy-4-{4-[(2-methyl-4-oxo-3,4-dihydro-quinazolin-6-ylmethyl)-prop-2-ynyl-amino]-benzoylamino}-butyrylamino)-pentanedioic acid TFA
   Show/Hide
C32H32F3N5O11
 1
1
IC50 = 27 nM
   TI
   LI
   LO
   TS
CP0885990
2-(4-Carboxy-4-{4-[(2-methyl-4-oxo-3,4-dihydro-quinazolin-6-ylmethyl)-prop-2-ynyl-amino]-benzoylamino}-butyrylamino)-pentanedioic acidTFA. 0.7 Et2O
   Show/Hide
C36H34F3N5O9
 1
1
IC50 = 30 nM
   TI
   LI
   LO
   TS
CP0507634
2-(4-{[(2,4-Diamino-quinazolin-6-yl)-methyl-amino]-methyl}-benzoylamino)-pentanedioic acid
   Show/Hide
C22H24N6O5
 1
1
IC50 = 33 nM
   TI
   LI
   LO
   TS
CP0897235
(R)-2-((S)-4-Carboxy-4-{4-[methyl-(2-methyl-4-oxo-3,4-dihydro-quinazolin-6-ylmethyl)-amino]-benzoylamino}-butyrylamino)-pentanedioic acid TFA
   Show/Hide
C30H32F3N5O11
 1
1
IC50 = 34 nM
   TI
   LI
   LO
   TS
CP0907047
(S)-2-((S)-4-Carboxy-4-{4-[(2-methyl-4-oxo-3,4-dihydro-quinazolin-6-ylmethyl)-prop-2-ynyl-amino]-benzoylamino}-butyrylamino)-pentanedioic acid TFA
   Show/Hide
C32H32F3N5O11
 1
1
IC50 = 37 nM
   TI
   LI
   LO
   TS
CP0060771
(S)-2-(4-(((2-methyl-4-oxo-3,4-dihydroquinazolin-6-yl)methyl)(prop-2-ynyl)amino)benzamido)pentanedioic acid
   Show/Hide
C25H24N4O6
 1
1
IC50 = 40 nM
   TI
   LI
   LO
   TS
CP0897090
2-{4-[(2-Amino-4-chloro-quinolin-6-ylmethyl)-prop-2-ynyl-amino]-2-fluoro-benzoylamino}-pentanedioic acid hydrochloride hydrate
   Show/Hide
C25H23Cl2FN4O5
 1
1
IC50 = 48 nM
   TI
   LI
   LO
   TS
CP0372616
(S)-5-fluoro-4-hydroxy-1-(3-oxo-3,6-dihydro-2H-pyran-2-yl)pyrimidin-2(1H)-one
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C9H7FN2O4
 6
1
IC50 = 63 nM
   TI
   LI
   LO
   TS
2
IC50 = 71 nM
   TI
   LI
   LO
   TS
3
IC50 = 830 nM
   TI
   LI
   LO
   TS
4
IC50 = 950 nM
   TI
   LI
   LO
   TS
5
IC50 = 8100 nM
   TI
   LI
   LO
   TS
6
IC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0493566
2-{4-[(2,4-Dichloro-quinolin-6-ylmethyl)-prop-2-ynyl-amino]-benzoylamino}-pentanedioic acid ; hydrate
   Show/Hide
C25H21Cl2N3O5
 1
1
IC50 = 64 nM
   TI
   LI
   LO
   TS
CP0409799
2-{4-[(4-Chloro-2-methyl-quinolin-6-ylmethyl)-prop-2-ynyl-amino]-2-fluoro-benzoylamino}-pentanedioic acid
   Show/Hide
C26H23ClFN3O5
 1
1
IC50 = 66 nM
   TI
   LI
   LO
   TS
CP0916072
2-{2,6-Difluoro-4-[(2-methyl-4-oxo-3,4-dihydro-quinazolin-6-ylmethyl)-prop-2-ynyl-amino]-benzoylamino}-pentanedioic acid hydrate (H2O)
   Show/Hide
C25H22F2N4O6
 1
1
IC50 = 80 nM
   TI
   LI
   LO
   TS
CP0416016
2-{4-[(2-Amino-4-chloro-quinolin-6-ylmethyl)-prop-2-ynyl-amino]-benzoylamino}-pentanedioic acid ; hydrate
   Show/Hide
C25H23ClN4O5
 1
1
IC50 = 96 nM
   TI
   LI
   LO
   TS
CP0497895
2-{4-[(4-Bromo-2-methyl-quinolin-6-ylmethyl)-prop-2-ynyl-amino]-2-fluoro-benzoylamino}-pentanedioic acid ; hydrate
   Show/Hide
C26H23BrFN3O5
 1
1
IC50 = 96 nM
   TI
   LI
   LO
   TS
CP0880998
2-{4-[(2,4-Diamino-5-chloro-quinazolin-6-ylamino)-methyl]-benzoylamino}-pentanedioic acid
   Show/Hide
C21H21ClN6O5
 1
1
IC50 = 98 nM
   TI
   LI
   LO
   TS
CP0677498
2-{2-Fluoro-4-[methyl-(2-methyl-4-oxo-3,4-dihydro-quinazolin-6-ylmethyl)-amino]-benzoylamino}-pentanedioic acid ;hydrate (H2O)
   Show/Hide
C23H23FN4O6
 1
1
IC50 = 120 nM
   TI
   LI
   LO
   TS
CP0462832
2-{4-[(2-Chloro-4-methyl-quinolin-6-ylmethyl)-prop-2-ynyl-amino]-benzoylamino}-pentanedioic acid ; hydrate
   Show/Hide
C26H24ClN3O5
 1
1
IC50 = 120 nM
   TI
   LI
   LO
   TS
CP0064255
2-{4-[(2-Amino-4-hydroxy-quinazolin-6-ylmethyl)-methyl-amino]-benzoylamino}-pentanedioic acid
   Show/Hide
C22H23N5O6
 2
1
IC50 = 130 nM
   TI
   LI
   LO
   TS
2
IC50 = 360 nM
   TI
   LI
   LO
   TS
CP0672452
2-(4-((2,4-diamino-5-methylquinazolin-6-ylamino)methyl)benzamido)pentanedioic acid
   Show/Hide
C22H24N6O5
 1
1
IC50 = 150 nM
   TI
   LI
   LO
   TS
CP0437855
2-{4-[(4-Chloro-2-trifluoromethyl-quinolin-6-ylmethyl)-prop-2-ynyl-amino]-benzoylamino}-pentanedioic acid ; hydrate
   Show/Hide
C26H21ClF3N3O5
 1
1
IC50 = 150 nM
   TI
   LI
   LO
   TS
CP0505805
2-{4-[(2-Chloro-4-methoxy-quinolin-6-ylmethyl)-prop-2-ynyl-amino]-benzoylamino}-pentanedioic acid ; hydrate
   Show/Hide
C26H24ClN3O6
 1
1
IC50 = 150 nM
   TI
   LI
   LO
   TS
CP0805382
2-(4-((2,4-diamino-5-chloroquinazolin-6-yl)methylamino)benzamido)pentanedioic acid
   Show/Hide
C21H21ClN6O5
 1
1
IC50 = 190 nM
   TI
   LI
   LO
   TS
CP0853666
2-(4-{[(2-Amino-4-hydroxy-quinazolin-6-yl)-methyl-amino]-methyl}-benzoylamino)-pentanedioic acid
   Show/Hide
C22H23N5O6
 1
1
IC50 = 200 nM
   TI
   LI
   LO
   TS
CP0686586
2-(4-((2-amino-4-hydroxyquinazolin-6-yl)methylthio)benzamido)pentanedioic acid
   Show/Hide
C21H20N4O6S
 1
1
IC50 = 220 nM
   TI
   LI
   LO
   TS
CP0505526
2-{4-[(4-Bromo-2-methyl-quinolin-6-ylmethyl)-prop-2-ynyl-amino]-benzoylamino}-pentanedioic acid ; hydrate
   Show/Hide
C26H24BrN3O5
 1
1
IC50 = 220 nM
   TI
   LI
   LO
   TS
CP0502410
2-{4-[(4-Chloro-2-methyl-quinolin-6-ylmethyl)-prop-2-ynyl-amino]-benzoylamino}-pentanedioic acid ; hydrate
   Show/Hide
C26H24ClN3O5
 1
1
IC50 = 250 nM
   TI
   LI
   LO
   TS
CP0503649
2-{4-[Allyl-(2-amino-4-oxo-3,4-dihydro-quinazolin-6-ylmethyl)-amino]-benzoylamino}-pentanedioic acid
   Show/Hide
C24H25N5O6
 1
1
IC50 = 280 nM
   TI
   LI
   LO
   TS
CP0039704
(S)-2-(4-(methyl((2-methyl-4-oxo-3,4-dihydroquinazolin-6-yl)methyl)amino)benzamido)pentanedioic acid
   Show/Hide
C23H24N4O6
 1
1
IC50 = 300 nM
   TI
   LI
   LO
   TS
CP0444084
2-{4-[(2-Amino-4-methyl-quinolin-6-ylmethyl)-prop-2-ynyl-amino]-benzoylamino}-pentanedioic acid ; hydrate
   Show/Hide
C26H26N4O5
 1
1
IC50 = 350 nM
   TI
   LI
   LO
   TS
CP0372614
5-fluoro-1-[(6S)-5-methylidene-2H-pyran-6-yl]pyrimidine-2,4-dione
   Show/Hide
C10H9FN2O3
 5
1
IC50 = 430 nM
   TI
   LI
   LO
   TS
2
IC50 = 2200 nM
   TI
   LI
   LO
   TS
3
IC50 = 8700 nM
   TI
   LI
   LO
   TS
4
IC50 = 9300 nM
   TI
   LI
   LO
   TS
5
IC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0395506
2-{4-[(2,4-Diamino-quinazolin-6-ylamino)-methyl]-benzoylamino}-pentanedioic acid
   Show/Hide
C21H22N6O5
 1
1
IC50 = 550 nM
   TI
   LI
   LO
   TS
CP0372615
1-[(2S,4S,5R)-4,5-dihydroxy-3-methylideneoxan-2-yl]-5-fluoropyrimidine-2,4-dione
   Show/Hide
C10H11FN2O5
 6
1
IC50 = 570 nM
   TI
   LI
   LO
   TS
2
IC50 = 3600 nM
   TI
   LI
   LO
   TS
3
IC50 = 5400 nM
   TI
   LI
   LO
   TS
4
IC50 = 5500 nM
   TI
   LI
   LO
   TS
5
IC50 = 8200 nM
   TI
   LI
   LO
   TS
6
IC50 >= 10000 nM
   TI
   LI
   LO
   TS
CP0434649
2-{4-[(2,4-Diamino-quinazolin-6-ylmethyl)-methyl-amino]-benzoylamino}-pentanedioic acid
   Show/Hide
C22H24N6O5
 1
1
IC50 = 600 nM
   TI
   LI
   LO
   TS
CP0920912
2-{2,5-Difluoro-4-[(2-methyl-4-oxo-3,4-dihydro-quinazolin-6-ylmethyl)-prop-2-ynyl-amino]-benzoylamino}-pentanedioic acid ;hydrate (0.5H2O)
   Show/Hide
C25H22F2N4O6
 1
1
IC50 = 600 nM
   TI
   LI
   LO
   TS
CP0391320
(2S)-2-[[4-[[4-chloro-2-(fluoromethyl)quinolin-6-yl]methyl-prop-2-ynylamino]benzoyl]amino]pentanedioic acid
   Show/Hide
C26H23ClFN3O5
 1
1
IC50 = 620 nM
   TI
   LI
   LO
   TS
CP0886430
2-(4-{[(2-Amino-4-hydroxy-5-methyl-quinazolin-6-yl)-methyl-amino]-methyl}-benzoylamino)-pentanedioic acid
   Show/Hide
C23H25N5O6
 1
1
IC50 = 700 nM
   TI
   LI
   LO
   TS
CP0427269
2-{4-[(4-Chloro-2-methyl-quinolin-6-ylmethyl)-ethyl-amino]-benzoylamino}-pentanedioic acid ; hydrate
   Show/Hide
C25H26ClN3O5
 1
1
IC50 = 740 nM
   TI
   LI
   LO
   TS
CP0453649
2-{4-[(2,4-Dimethyl-quinolin-6-ylmethyl)-prop-2-ynyl-amino]-benzoylamino}-pentanedioic acid ; hydrate
   Show/Hide
C27H27N3O5
 1
1
IC50 = 800 nM
   TI
   LI
   LO
   TS
CP0947325
2-{2,6-Difluoro-4-[methyl-(2-methyl-4-oxo-3,4-dihydro-quinazolin-6-ylmethyl)-amino]-benzoylamino}-pentanedioic acid ;hydrate (1.25H2O)
   Show/Hide
C23H22F2N4O6
 1
1
IC50 = 950 nM
   TI
   LI
   LO
   TS
CP0495172
2-{4-[(4-Chloro-2-ethyl-quinolin-6-ylmethyl)-prop-2-ynyl-amino]-benzoylamino}-pentanedioic acid ; hydrate
   Show/Hide
C27H26ClN3O5
 1
1
IC50 = 990 nM
   TI
   LI
   LO
   TS
CP0947321
2-{2,3-Difluoro-4-[methyl-(2-methyl-4-oxo-3,4-dihydro-quinazolin-6-ylmethyl)-amino]-benzoylamino}-pentanedioic acid ;hydrate (0.75H2O)
   Show/Hide
C23H22F2N4O6
 1
1
IC50 = 1000 nM
   TI
   LI
   LO
   TS
CP0527642
2-{4-[(4-Chloro-2-hydroxymethyl-quinolin-6-ylmethyl)-ethyl-amino]-benzoylamino}-pentanedioic acid ; hydrate
   Show/Hide
C25H26ClN3O6
 1
1
IC50 = 1050 nM
   TI
   LI
   LO
   TS
CP0507481
2-{4-[Methyl-(4-oxo-3,4-dihydro-quinazolin-6-ylmethyl)-amino]-benzoylamino}-pentanedioic acid
   Show/Hide
C22H22N4O6
 1
1
IC50 = 1060 nM
   TI
   LI
   LO
   TS
CP0899706
2-{2,5-Difluoro-4-[methyl-(2-methyl-4-oxo-3,4-dihydro-quinazolin-6-ylmethyl)-amino]-benzoylamino}-pentanedioic acid ;hydrate (H2O)
   Show/Hide
C23H22F2N4O6
 1
1
IC50 = 1100 nM
   TI
   LI
   LO
   TS
CP0517114
2-{4-[Allyl-(4-oxo-3,4-dihydro-quinazolin-6-ylmethyl)-amino]-benzoylamino}-pentanedioic acid
   Show/Hide
C24H24N4O6
 1
1
IC50 = 1120 nM
   TI
   LI
   LO
   TS
CP0917677
2-{4-[(4-Chloro-quinolin-6-ylmethyl)-ethyl-amino]-benzoylamino}-pentanedioic acid; compound with formic acid hydrate
   Show/Hide
C25H26ClN3O7
 1
1
IC50 = 1130 nM
   TI
   LI
   LO
   TS
CP0772248
2-{3-Fluoro-4-[methyl-(2-methyl-4-oxo-3,4-dihydro-quinazolin-6-ylmethyl)-amino]-benzoylamino}-pentanedioic acid ;hydrate (H2O)
   Show/Hide
C23H23FN4O6
 1
1
IC50 = 1140 nM
   TI
   LI
   LO
   TS
CP0903163
2-{4-[(2-Acetylamino-4-chloro-quinolin-6-ylmethyl)-prop-2-ynyl-amino]-benzoylamino}-pentanedioic acid TFA with hydrate
   Show/Hide
C29H26ClF3N4O8
 1
1
IC50 = 1200 nM
   TI
   LI
   LO
   TS
CP0760762
SID144917
   Show/Hide
C21H21N5O6
 1
1
IC50 = 1300 nM
   TI
   LI
   LO
   TS
CP0678039
2-{3-Fluoro-4-[(2-methyl-4-oxo-3,4-dihydro-quinazolin-6-ylmethyl)-prop-2-ynyl-amino]-benzoylamino}-pentanedioic acid ;hydrate (H2O)
   Show/Hide
C25H23FN4O6
 1
1
IC50 = 1430 nM
   TI
   LI
   LO
   TS
CP0440223
2-{4-[(4-Cyano-2-methyl-quinolin-6-ylmethyl)-prop-2-ynyl-amino]-benzoylamino}-pentanedioic acid ; hydrate
   Show/Hide
C27H24N4O5
 1
1
IC50 = 1500 nM
   TI
   LI
   LO
   TS
CP0847326
2-{2,3-Difluoro-4-[(2-methyl-4-oxo-3,4-dihydro-quinazolin-6-ylmethyl)-prop-2-ynyl-amino]-benzoylamino}-pentanedioic acid ;hydrate (2H2O)
   Show/Hide
C25H22F2N4O6
 1
1
IC50 = 1700 nM
   TI
   LI
   LO
   TS
CP0440214
2-{4-[(2-Carbamoyl-4-chloro-quinolin-6-ylmethyl)-prop-2-ynyl-amino]-benzoylamino}-pentanedioic acid ; hydrate
   Show/Hide
C26H23ClN4O6
 1
1
IC50 = 1900 nM
   TI
   LI
   LO
   TS
CP0528125
2-{4-[(2-Amino-4-methoxy-quinolin-6-ylmethyl)-ethyl-amino]-benzoylamino}-pentanedioic acid ; hydrate
   Show/Hide
C25H28N4O6
 1
1
IC50 = 1900 nM
   TI
   LI
   LO
   TS
CP0672453
2-{4-[(2-Amino-4-hydroxy-5-methyl-quinazolin-6-ylamino)-methyl]-benzoylamino}-pentanedioic acid
   Show/Hide
C22H23N5O6
 1
1
IC50 = 2200 nM
   TI
   LI
   LO
   TS
CP0460781
2-{4-[(4-Chloro-2-methyl-quinolin-6-ylmethyl)-methyl-amino]-benzoylamino}-pentanedioic acid ; hydrate
   Show/Hide
C24H24ClN3O5
 1
1
IC50 = 2300 nM
   TI
   LI
   LO
   TS
CP0527743
2-{4-[(2-Chloro-quinolin-6-ylmethyl)-prop-2-ynyl-amino]-benzoylamino}-pentanedioic acid ; hydrate
   Show/Hide
C25H22ClN3O5
 1
1
IC50 = 2600 nM
   TI
   LI
   LO
   TS
CP0887123
2-(4-{[Allyl-(2,4-diamino-quinazolin-6-yl)-amino]-methyl}-benzoylamino)-pentanedioic acid
   Show/Hide
C24H26N6O5
 1
1
IC50 = 3200 nM
   TI
   LI
   LO
   TS
CP0040464
2-{4-[(2-Amino-4-hydroxy-quinazolin-6-ylmethyl)-amino]-benzoylamino}-pentanedioic acid
   Show/Hide
C21H21N5O6
 1
1
IC50 = 3400 nM
   TI
   LI
   LO
   TS
CP0913490
2-{4-[(2-Amino-5-chloro-4-hydroxy-quinazolin-6-ylamino)-methyl]-benzoylamino}-pentanedioic acid
   Show/Hide
C21H20ClN5O6
 1
1
IC50 = 4000 nM
   TI
   LI
   LO
   TS
CP0867763
2-(4-{[(2,4-Diamino-quinazolin-6-yl)-prop-2-ynyl-amino]-methyl}-benzoylamino)-pentanedioic acid
   Show/Hide
C24H24N6O5
 1
1
IC50 = 4400 nM
   TI
   LI
   LO
   TS
CP0056680
2-{4-[(2,4-Diamino-quinazolin-6-ylmethyl)-amino]-benzoylamino}-pentanedioic acid
   Show/Hide
C21H22N6O5
 1
1
IC50 = 5000 nM
   TI
   LI
   LO
   TS
CP0502292
2-{4-[(4-Methoxy-2-methyl-quinolin-6-ylmethyl)-prop-2-ynyl-amino]-benzoylamino}-pentanedioic acid ; hydrate
   Show/Hide
C27H27N3O6
 1
1
IC50 = 6000 nM
   TI
   LI
   LO
   TS
CP0881005
2-(4-{[Allyl-(2-amino-4-hydroxy-quinazolin-6-yl)-amino]-methyl}-benzoylamino)-pentanedioic acid
   Show/Hide
C24H25N5O6
 1
1
IC50 = 6100 nM
   TI
   LI
   LO
   TS
CP0535758
2-{4-[(4-Hydroxy-2-methyl-quinolin-6-ylmethyl)-prop-2-ynyl-amino]-benzoylamino}-pentanedioic acid ; hydrate
   Show/Hide
C26H25N3O6
 1
1
IC50 = 6300 nM
   TI
   LI
   LO
   TS
CP0469280
2-{4-[(2-Methyl-quinolin-6-ylmethyl)-prop-2-ynyl-amino]-benzoylamino}-pentanedioic acid ; hydrate
   Show/Hide
C26H25N3O5
 1
1
IC50 = 7900 nM
   TI
   LI
   LO
   TS
CP0859541
2-(4-{[(2-Amino-4-hydroxy-quinazolin-6-yl)-prop-2-ynyl-amino]-methyl}-benzoylamino)-pentanedioic acid
   Show/Hide
C24H23N5O6
 1
1
IC50 = 8600 nM
   TI
   LI
   LO
   TS
CP0543962
; hydrate2-{4-[(2-Methyl-4-methylsulfanyl-quinolin-6-ylmethyl)-prop-2-ynyl-amino]-benzoylamino}-pentanedioic acid ; hydrate
   Show/Hide
C27H27N3O5S
 1
1
IC50 = 8900 nM
   TI
   LI
   LO
   TS
CP0502698
2-{4-[(4-Chloro-2-methoxy-quinolin-6-ylmethyl)-prop-2-ynyl-amino]-benzoylamino}-pentanedioic acid ; hydrate
   Show/Hide
C26H24ClN3O6
 1
1
IC50 = 9000 nM
   TI
   LI
   LO
   TS
CP0080967
2-{4-[(2-Amino-4-hydroxy-quinazolin-6-ylmethyl)-formyl-amino]-benzoylamino}-pentanedioic acid
   Show/Hide
C22H21N5O7
 1
1
IC50 = 9800 nM
   TI
   LI
   LO
   TS
CP0163000
2-{4-[(2,4-Diamino-quinazolin-6-ylmethyl)-formyl-amino]-benzoylamino}-pentanedioic acid
   Show/Hide
C22H22N6O6
 1
1
IC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0378548
2-(4-{[(2,4-Diamino-quinazolin-6-yl)-formyl-amino]-methyl}-benzoylamino)-pentanedioic acid
   Show/Hide
C22H22N6O6
 1
1
IC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0920223
2-(4-{[(2-Amino-4-hydroxy-quinazolin-6-yl)-formyl-amino]-methyl}-benzoylamino)-pentanedioic acid
   Show/Hide
C22H21N5O7
 1
1
IC50 = 11000 nM
   TI
   LI
   LO
   TS
CP0688707
2-(4-((2-amino-4-hydroxyquinazolin-6-yl)methoxy)benzamido)pentanedioic acid
   Show/Hide
C21H20N4O7
 1
1
IC50 = 12000 nM
   TI
   LI
   LO
   TS
CP0036197
2-[(4-{[(2,4-diaminopteridin-6-yl)methyl](methyl)amino}phenyl)formamido]pentanedioic acid
   Show/Hide
C20H22N8O5
 1
1
IC50 = 20000 nM
   TI
   LI
   LO
   TS
CP0449422
2-{4-[(2-Carboxy-4-chloro-quinolin-6-ylmethyl)-prop-2-ynyl-amino]-benzoylamino}-pentanedioic acid ; hydrate
   Show/Hide
C26H22ClN3O7
 1
1
IC50 = 31000 nM
   TI
   LI
   LO
   TS
CP0441711
2-{4-[(4-Chloro-2-methyl-quinolin-6-ylmethyl)-amino]-benzoylamino}-pentanedioic acid ; hydrate
   Show/Hide
C23H22ClN3O5
 1
1
IC50 = 38000 nM
   TI
   LI
   LO
   TS
CP0506674
(2S)-5-[[(1R)-3-carboxy-1-(2H-tetrazol-5-yl)propyl]amino]-2-[[4-[[(6S)-2-methyl-4-oxo-3,6,7,8-tetrahydrocyclopenta[g]quinazolin-6-yl]-prop-2-ynylamino]benzoyl]amino]-5-oxopentanoic acid
   Show/Hide
C32H33N9O7
 1
1
Ki = 0.17 nM
   TI
   LI
   LO
   TS
CP0308127
4-[3-Carboxy-1-(1H-tetrazol-5-yl)-propylcarbamoyl]-2-{4-[(2-methyl-4-oxo-4,6,7,8-tetrahydro-3H-cyclopenta[g]quinazolin-6-yl)-prop-2-ynyl-amino]-benzoylamino}-butyric acid
   Show/Hide
C32H33N9O7
 1
1
Ki = 0.2 nM
   TI
   LI
   LO
   TS
CP0891269
(S)-4-[3-Carboxy-1-(1H-tetrazol-5-yl)-propylcarbamoyl]-2-{4-[(2-methyl-4-oxo-4,6,7,8-tetrahydro-3H-cyclopenta[g]quinazolin-6-yl)-prop-2-ynyl-amino]-benzoylamino}-butyric acid
   Show/Hide
C32H33N9O7
 1
1
Ki = 0.2 nM
   TI
   LI
   LO
   TS
CP0448847
(2S)-2-[[(2S)-4-carboxy-2-[[4-[(2,7-dimethyl-4-oxo-3H-quinazolin-6-yl)methyl-prop-2-ynylamino]-2-fluorobenzoyl]amino]butanoyl]-prop-2-ynylamino]pentanedioic acid
   Show/Hide
C34H34FN5O9
 1
1
Ki = 0.21 nM
   TI
   LI
   LO
   TS
CP0359177
2-(4-Carboxy-4-{4-[(2-methyl-4-oxo-4,6,7,8-tetrahydro-3H-cyclopenta[g]quinazolin-6-yl)-prop-2-ynyl-amino]-benzoylamino}-butyrylamino)-4-(1-carboxymethyl-1H-tetrazol-5-yl)-butyric acid
   Show/Hide
C34H35N9O9
 1
1
Ki = 0.26 nM
   TI
   LI
   LO
   TS
CP0402081
(2R)-2-[[(4S)-4-carboxy-4-[[4-[[(6S)-2-methyl-4-oxo-3,6,7,8-tetrahydrocyclopenta[g]quinazolin-6-yl]-prop-2-ynylamino]benzoyl]amino]butanoyl]amino]pentanedioic acid
   Show/Hide
C32H33N5O9
 1
1
Ki = 0.33 nM
   TI
   LI
   LO
   TS
CP0448997
(2S)-2-[[(2S)-4-carboxy-2-[[4-[(2,7-dimethyl-4-oxo-3H-quinazolin-6-yl)methyl-prop-2-ynylamino]-2-fluorobenzoyl]amino]butanoyl]-ethylamino]pentanedioic acid
   Show/Hide
C33H36FN5O9
 1
1
Ki = 0.35 nM
   TI
   LI
   LO
   TS
CP0280456
2-(4-Carboxy-4-{4-[(2-methyl-4-oxo-4,6,7,8-tetrahydro-3H-cyclopenta[g]quinazolin-6-yl)-prop-2-ynyl-amino]-benzoylamino}-butyrylamino)-pentanedioic acid
   Show/Hide
C32H33N5O9
 1
1
Ki = 0.42 nM
   TI
   LI
   LO
   TS
CP0880980
2-((S)-4-Carboxy-4-{4-[(2-methyl-4-oxo-4,6,7,8-tetrahydro-3H-cyclopenta[g]quinazolin-6-yl)-prop-2-ynyl-amino]-benzoylamino}-butyrylamino)-pentanedioic acid
   Show/Hide
C32H33N5O9
 1
1
Ki = 0.42 nM
   TI
   LI
   LO
   TS
CP0535643
(2S)-2-[[4-[[(6S)-2-methyl-4-oxo-3,6,7,8-tetrahydrocyclopenta[g]quinazolin-6-yl]-prop-2-ynylamino]benzoyl]amino]-5-(1H-1,2,4-triazol-5-ylsulfonyl)pentanoic acid
   Show/Hide
C29H29N7O6S
 1
1
Ki = 0.71 nM
   TI
   LI
   LO
   TS
CP0259513
(S)-2-{4-[(2-Methyl-4-oxo-4,6,7,8-tetrahydro-3H-cyclopenta[g]quinazolin-6-yl)-prop-2-ynyl-amino]-benzoylamino}-5-(1H-[1,2,4]triazole-3-sulfonyl)-pentanoic acid
   Show/Hide
C29H29N7O6S
 1
1
Ki = 0.78 nM
   TI
   LI
   LO
   TS
CP0545267
(2R)-2-[[(4S)-4-carboxy-4-[[4-[(2-methyl-4-oxo-3,6,7,8-tetrahydrocyclopenta[g]quinazolin-6-yl)-prop-2-ynylamino]benzoyl]amino]butanoyl]-methylamino]pentanedioic acid
   Show/Hide
C33H35N5O9
 1
1
Ki = 0.78 nM
   TI
   LI
   LO
   TS
CP0514962
(2S)-2-[[(2S)-4-carboxy-2-[[4-[(2,7-dimethyl-4-oxo-3H-quinazolin-6-yl)methyl-prop-2-ynylamino]-2-fluorobenzoyl]amino]butanoyl]-methylamino]pentanedioic acid
   Show/Hide
C32H34FN5O9
 1
1
Ki = 1.1 nM
   TI
   LI
   LO
   TS
CP0394263
(2S)-5-[[(1R)-1-carboxyethyl]amino]-2-[[4-[(2-methyl-4-oxo-3,6,7,8-tetrahydrocyclopenta[g]quinazolin-6-yl)-prop-2-ynylamino]benzoyl]amino]-5-oxopentanoic acid
   Show/Hide
C30H31N5O7
 1
1
Ki = 1.1 nM
   TI
   LI
   LO
   TS
CP0424055
(2S)-4-[2-(carboxymethyl)tetrazol-5-yl]-2-[[4-[(2-methyl-4-oxo-3,6,7,8-tetrahydrocyclopenta[g]quinazolin-6-yl)-prop-2-ynylamino]benzoyl]amino]butanoic acid
   Show/Hide
C29H28N8O6
 1
1
Ki = 1.7 nM
   TI
   LI
   LO
   TS
CP0383747
(2S)-2-[[(2S)-4-carboxy-2-[[4-[(2-methyl-4-oxo-3H-quinazolin-6-yl)methyl-prop-2-ynylamino]benzoyl]amino]butanoyl]amino]pentanedioic acid
   Show/Hide
C30H31N5O9
 1
1
Ki = 2 nM
   TI
   LI
   LO
   TS
CP0244326
(R)-2-((S)-4-Carboxy-4-{4-[(2,7-dimethyl-4-oxo-3,4-dihydro-quinazolin-6-ylmethyl)-prop-2-ynyl-amino]-benzoylamino}-butyrylamino)-pentanedioic acid; TFA
   Show/Hide
C31H33N5O9
 1
1
Ki = 2 nM
   TI
   LI
   LO
   TS
CP0523970
(2S)-4-[1-(3-carboxypropyl)tetrazol-5-yl]-2-[[4-[(2-methyl-4-oxo-3,6,7,8-tetrahydrocyclopenta[g]quinazolin-6-yl)-prop-2-ynylamino]benzoyl]amino]butanoic acid
   Show/Hide
C31H32N8O6
 1
1
Ki = 2 nM
   TI
   LI
   LO
   TS
CP0449416
(2S)-5-[[(1R)-3-carboxy-1-(2H-tetrazol-5-yl)propyl]amino]-2-[[4-[[(6R)-2-methyl-4-oxo-3,6,7,8-tetrahydrocyclopenta[g]quinazolin-6-yl]-prop-2-ynylamino]benzoyl]amino]-5-oxopentanoic acid
   Show/Hide
C32H33N9O7
 1
1
Ki = 2.1 nM
   TI
   LI
   LO
   TS
CP0208036
2-{4-[(2-Methyl-4-oxo-4,6,7,8-tetrahydro-3H-cyclopenta[g]quinazolin-6-yl)-prop-2-ynyl-amino]-benzoylamino}-4-[1-(1H-tetrazol-5-yl)-ethylcarbamoyl]-butyric acid
   Show/Hide
C30H31N9O5
 1
1
Ki = 2.2 nM
   TI
   LI
   LO
   TS
CP0487363
(2S)-4-[1-[2-[[(1R)-1-carboxyethyl]amino]-2-oxoethyl]tetrazol-5-yl]-2-[[4-[(2-methyl-4-oxo-3,6,7,8-tetrahydrocyclopenta[g]quinazolin-6-yl)-prop-2-ynylamino]benzoyl]amino]butanoic acid
   Show/Hide
C32H33N9O7
 1
1
Ki = 2.2 nM
   TI
   LI
   LO
   TS
CP0111571
4-(2-Benzenesulfonylamino-1-methyl-2-oxo-ethylcarbamoyl)-2-{4-[(2-methyl-4-oxo-4,6,7,8-tetrahydro-3H-cyclopenta[g]quinazolin-6-yl)-prop-2-ynyl-amino]-benzoylamino}-butyric acid
   Show/Hide
C36H36N6O8S
 1
1
Ki = 2.4 nM
   TI
   LI
   LO
   TS
CP0565389
(2S)-4-[1-(carboxymethyl)tetrazol-5-yl]-2-[[4-[(2-methyl-4-oxo-3,6,7,8-tetrahydrocyclopenta[g]quinazolin-6-yl)-prop-2-ynylamino]benzoyl]amino]butanoic acid
   Show/Hide
C29H28N8O6
 1
1
Ki = 2.4 nM
   TI
   LI
   LO
   TS
CP0460988
(2S)-2-[[(2S)-4-carboxy-2-[[4-[(2,7-dimethyl-4-oxo-3H-quinazolin-6-yl)methyl-prop-2-ynylamino]benzoyl]amino]butanoyl]-methylamino]pentanedioic acid
   Show/Hide
C32H35N5O9
 1
1
Ki = 2.6 nM
   TI
   LI
   LO
   TS
CP0538229
(2S)-2-[[4-[(2-methyl-4-oxo-3,6,7,8-tetrahydrocyclopenta[g]quinazolin-6-yl)-prop-2-ynylamino]benzoyl]amino]-5-oxo-5-[[(1R)-1-(2H-tetrazol-5-yl)butyl]amino]pentanoic acid
   Show/Hide
C32H35N9O5
 1
1
Ki = 2.6 nM
   TI
   LI
   LO
   TS
CP0535306
(2S)-2-[[(2S)-4-carboxy-2-[[4-[(2,7-dimethyl-4-oxo-3H-quinazolin-6-yl)methyl-methylamino]-2-fluorobenzoyl]amino]butanoyl]-methylamino]pentanedioic acid
   Show/Hide
C30H34FN5O9
 1
1
Ki = 3 nM
   TI
   LI
   LO
   TS
CP0403730
(2R)-2-[[(4S)-4-carboxy-4-[[4-[[(6R)-2-methyl-4-oxo-3,6,7,8-tetrahydrocyclopenta[g]quinazolin-6-yl]-prop-2-ynylamino]benzoyl]amino]butanoyl]amino]pentanedioic acid
   Show/Hide
C32H33N5O9
 1
1
Ki = 3.5 nM
   TI
   LI
   LO
   TS
CP0448983
(2S)-2-[[(2S)-4-carboxy-2-[[2-fluoro-4-[(2-methyl-4-oxo-3H-quinazolin-6-yl)methyl-prop-2-ynylamino]benzoyl]amino]butanoyl]-methylamino]pentanedioic acid
   Show/Hide
C31H32FN5O9
 1
1
Ki = 4 nM
   TI
   LI
   LO
   TS
CP0510624
(2S)-2-[[(2S)-4-carboxy-2-[[4-[(2,7-dimethyl-4-oxo-3H-quinazolin-6-yl)methyl-methylamino]benzoyl]amino]butanoyl]-methylamino]pentanedioic acid
   Show/Hide
C30H35N5O9
 1
1
Ki = 8.2 nM
   TI
   LI
   LO
   TS
CP0394523
(2S)-2-[[(2S)-4-carboxy-2-[[4-[(2-methyl-4-oxo-3H-quinazolin-6-yl)methyl-prop-2-ynylamino]benzoyl]amino]pentanoyl]amino]pentanedioic acid
   Show/Hide
C31H33N5O9
 1
1
Ki = 8.6 nM
   TI
   LI
   LO
   TS
CP0376733
(2S)-2-[[(2S)-4-carboxy-2-[[4-[(2-methyl-4-oxo-3H-quinazolin-6-yl)methyl-prop-2-ynylamino]benzoyl]amino]butanoyl]-methylamino]pentanedioic acid
   Show/Hide
C31H33N5O9
 1
1
Ki = 11 nM
   TI
   LI
   LO
   TS
CP0459333
(2S)-2-[[(2S)-4-carboxy-4-methyl-2-[[4-[(2-methyl-4-oxo-3H-quinazolin-6-yl)methyl-prop-2-ynylamino]benzoyl]amino]pentanoyl]amino]pentanedioic acid
   Show/Hide
C32H35N5O9
 1
1
Ki = 18 nM
   TI
   LI
   LO
   TS
CP0063297
(R)-5-Fluoro-1-((4S,5R)-4-hydroxy-5-methylphosphate-tetrahydro-furan-2-yl)-1H-pyrimidine-2,4-dione
   Show/Hide
C9H12FN2O8P
 2
1
Ki = 20 nM
   TI
   LI
   LO
   TS
2
Ki = 30 nM
   TI
   LI
   LO
   TS
CP0457012
(2S)-2-[[(2S)-4-carboxy-2-[[2-fluoro-4-[methyl-[(2-methyl-4-oxo-3H-quinazolin-6-yl)methyl]amino]benzoyl]amino]butanoyl]-methylamino]pentanedioic acid
   Show/Hide
C29H32FN5O9
 1
1
Ki = 23 nM
   TI
   LI
   LO
   TS
CP0457287
1-[(2S)-4-carboxy-2-[[4-[(2-methyl-4-oxo-3H-quinazolin-6-yl)methyl-prop-2-ynylamino]benzoyl]amino]butanoyl]pyrrolidine-2-carboxylic acid
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C30H31N5O7
 1
1
Ki = 35 nM
   TI
   LI
   LO
   TS
CP0530002
(4S)-5-(2-carboxypropan-2-ylamino)-4-[[4-[(2-methyl-4-oxo-3H-quinazolin-6-yl)methyl-prop-2-ynylamino]benzoyl]amino]-5-oxopentanoic acid
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C29H31N5O7
 1
1
Ki = 42 nM
   TI
   LI
   LO
   TS
CP0453345
(4S)-5-[carboxymethyl(methyl)amino]-4-[[4-[(2-methyl-4-oxo-3H-quinazolin-6-yl)methyl-prop-2-ynylamino]benzoyl]amino]-5-oxopentanoic acid
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C28H29N5O7
 1
1
Ki = 50 nM
   TI
   LI
   LO
   TS
CP0124670
[(2R,3S,5R)-5-(5-chloro-2,4-dioxopyrimidin-1-yl)-3-hydroxyoxolan-2-yl]methyl dihydrogen phosphate
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C9H12ClN2O8P
 2
1
Ki = 150 nM
   TI
   LI
   LO
   TS
2
Ki = 300 nM
   TI
   LI
   LO
   TS
CP0083302
[(2R,3S,5R)-5-(5-bromo-2,4-dioxopyrimidin-1-yl)-3-hydroxyoxolan-2-yl]methyl dihydrogen phosphate
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C9H12BrN2O8P
 2
1
Ki = 460 nM
   TI
   LI
   LO
   TS
2
Ki = 1500 nM
   TI
   LI
   LO
   TS
CP0857718
1-(beta-D-2-Deoxyribofuranosyl)-4-hydroxyamino-5-fluoropyrimidin-2(1H)-one 5'-monophosphate
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C9H13FN3O8P
 2
1
Ki = 800 nM
   TI
   LI
   LO
   TS
2
Ki = 1400 nM
   TI
   LI
   LO
   TS
CP0673433
((2R,3S,5R)-3-hydroxy-5-(5-(hydroxymethyl)-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)tetrahydrofuran-2-yl)methyl phosphate
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C10H15N2O9P
 2
1
Ki = 900 nM
   TI
   LI
   LO
   TS
2
Ki = 3700 nM
   TI
   LI
   LO
   TS
CP0503592
(2S)-2-[[4-[[(6R)-2-methyl-4-oxo-3,6,7,8-tetrahydrocyclopenta[g]quinazolin-6-yl]-prop-2-ynylamino]benzoyl]amino]-5-(1H-1,2,4-triazol-5-ylsulfonyl)pentanoic acid
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C29H29N7O6S
 1
1
Ki = 1200 nM
   TI
   LI
   LO
   TS
CP0723209
1-(beta-D-2-Deoxyribofuranosyl)-4-hydroxyaminopyrimidin-2(1H)-one 5'-monophosphate
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C9H14N3O8P
 2
1
Ki = 1700 nM
   TI
   LI
   LO
   TS
2
Ki = 9300 nM
   TI
   LI
   LO
   TS
CP0847443
1-(beta-D-2-Deoxyribofuranosyl)-4-hydroxyamino-5-hydroxymethylpyrimidin-2(1H)-one 5'-monophosphate
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C10H16N3O9P
 2
1
Ki = 1910 nM
   TI
   LI
   LO
   TS
2
Ki = 2180 nM
   TI
   LI
   LO
   TS
CP0849895
1-(beta-D-2-Deoxyribofuranosyl)-4-hydroxyamino-5-iodopyrimidin-2(1H)-one 5'-monophosphate
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C9H13IN3O8P
 2
1
Ki = 5700 nM
   TI
   LI
   LO
   TS
2
Ki = 7460 nM
   TI
   LI
   LO
   TS
CP0124669
[(2R,3S,5R)-3-hydroxy-5-(5-iodo-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methyl dihydrogen phosphate
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C9H12IN2O8P
 2
1
Ki = 6990 nM
   TI
   LI
   LO
   TS
2
Ki = 7680 nM
   TI
   LI
   LO
   TS
CP0731897
Phosphoric acid mono-[5-(4-amino-5-methyl-2-oxo-2H-pyrimidin-1-yl)-3-hydroxy-tetrahydro-furan-2-ylmethyl] ester
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C8H13N5OS2
 1
1
Ki = 7300 nM
   TI
   LI
   LO
   TS
CP0845706
1-(beta-D-2-Deoxyribofuranosyl)-4-hydroxyamino-5-chloropyrimidin-2(1H)-one 5'-monophosphate
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C9H13ClN3O8P
 2
1
Ki = 8400 nM
   TI
   LI
   LO
   TS
2
Ki = 8500 nM
   TI
   LI
   LO
   TS
CP0849982
1-(beta-D-2-Deoxyribofuranosyl)-4-hydroxyamino-5-bromopyrimidin-2(1H)-one 5'-monophosphate
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C9H13BrN3O8P
 2
1
Ki = 32100 nM
   TI
   LI
   LO
   TS
2
Ki = 36600 nM
   TI
   LI
   LO
   TS