General Information of the Compound
| Compound ID |
CP0063297
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| Compound Name |
(R)-5-Fluoro-1-((4S,5R)-4-hydroxy-5-methylphosphate-tetrahydro-furan-2-yl)-1H-pyrimidine-2,4-dione
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| Synonyms |
134-46-3
5'-Uridylic acid, 2'-deoxy-5-fluoro-
5'-Uridylic acid,2'-deoxy-5-fluoro-, homopolymer
5-FLUORO-2-DEOXYURIDINE MONOPHOSPHATE (FDUMP)
5-Fluoro-2'-Deoxyuridine-5'-Monophosphate
5-fluoro-2'-deoxyuridine-5'-monophosphate
5-fluorodeoxyuridine monophosphate
5FdUMP
7CJ707H131
88410-68-8
AC1L1RES
CHEBI:2129
CHEMBL886
DB03761
F-dUMP
FLUORODEOXYURIDYLATE
FdUMP
Poly(5'-FU)
Poly(5-fluoro-2'-deoxyuridylic acid)
Poly(dF5U)
UFP
UNII-7CJ707H131
[(2R,3S,5R)-5-(5-fluoro-2,4-dioxo-pyrimidin-1-yl)-3-hydroxy-tetrahydrofuran-2-yl]methyl dihydrogen phosphate
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| Structure |
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| Formula |
C9H12FN2O8P
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| Molecular Weight |
326.173
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| Canonical SMILES |
O[C@H]1C[C@@H](O[C@@H]1COP(O)(O)=O)n1cc(F)c(=O)[nH]c1=O
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| InChI |
InChI=1S/C9H12FN2O8P/c10-4-2-12(9(15)11-8(4)14)7-1-5(13)6(20-7)3-19-21(16,17)18/h2,5-7,13H,1,3H2,(H,11,14,15)(H2,16,17,18)/t5-,6+,7+/m0/s1
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| InChIKey |
HFEKDTCAMMOLQP-RRKCRQDMSA-N
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| CAS |
134-46-3
13932-36-0
144923-92-2
18453-22-0
35225-15-1
4660-71-3
88410-68-8
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| Physicochemical Property |
"RO5" indicates the cutoff set by lipinski's rule of five: (1) Molecular weight less than 500 Dalton; (2) xlogp less than 5; (3) No more than 5 hbonddonor (Hydrogen Bond Donor Count); (4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count); (5) No more than 10 rotbonds (Rotatable Bond Count). Show/Hide
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Map of Molecular Bioactivity Related to the Compound
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Map of Molecular Bioactivity Related to the Compound Compound Cell Line Protein Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity |
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Table of Molecular Bioactivities Related to the Compound
Clinical Information about the Compound
Drug 1 ( 5-Fluoro-2'-Deoxyuridine-5'-Monophosphate )
| Drug Name | 5-Fluoro-2'-Deoxyuridine-5'-Monophosphate | ||
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