General Information of the Compound
| Compound ID |
CP0077456
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| Compound Name |
1-(beta-D-2-deoxy-erythro-pentofuranosyl)-5-fluorouracil
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| Synonyms |
Sterile fudr (TN)
2'-Deoxy-5-fluorouridine
5 Fluorodeoxyuridine
5-FdUrd
5-Fluoro-2'-deoxyuridine
5-Fluoro-2-deoxyuridine
5-Fluoro-2-desoxyuridine
5-Fluorodeoxyuridine
5-Fluorouracil deoxyriboside
5-fluoro-1-((2r,4s,5r)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidine-2,4(1h,3h)-dione
50-91-9
5FdU
Deoxyfluorouridine
FDUR
FUDR
FdUrd
Floxiridina
Floxiridina [INN-Spanish]
Floxuridin
Floxuridine
Floxuridine/5-fluorouracil
Floxuridinum
Floxuridinum [INN-Latin]
Fluorodeoxyuridine
Fluoruridine deoxyribose
beta-5-Fluoro-2'-deoxyuridine
floxuridine
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| Structure |
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| Formula |
C9H11FN2O5
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| Molecular Weight |
246.194
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| Canonical SMILES |
OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O
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| InChI |
InChI=1S/C9H11FN2O5/c10-4-2-12(9(16)11-8(4)15)7-1-5(14)6(3-13)17-7/h2,5-7,13-14H,1,3H2,(H,11,15,16)/t5-,6+,7+/m0/s1
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| InChIKey |
ODKNJVUHOIMIIZ-RRKCRQDMSA-N
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| CAS |
50-91-9
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| Physicochemical Property |
"RO5" indicates the cutoff set by lipinski's rule of five: (1) Molecular weight less than 500 Dalton; (2) xlogp less than 5; (3) No more than 5 hbonddonor (Hydrogen Bond Donor Count); (4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count); (5) No more than 10 rotbonds (Rotatable Bond Count). Show/Hide
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Map of Molecular Bioactivity Related to the Compound
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Map of Molecular Bioactivity Related to the Compound Compound Cell Line Protein Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity |
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Table of Molecular Bioactivities Related to the Compound
Protein ID: PT06109, Geminin
Protein ID: PT02997, Isocitrate dehydrogenase [NADP] cytoplasmic
Protein ID: PT01883, Thymidylate synthase
Cell Viability or Cytotoxicity Assay
Clinical Information about the Compound