General Information of the Cell Line
Cell Line ID
CL000015
Cell Line Name
SW480
Synonyms
SW-480
SW 480
SW480E
Category
Cancer cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_0546
Tissue Information
Colon
Disease
Colon adenocarcinoma (NCIt: C4349)
Map of Molecular Bioactivity Related to the Cell Line
Map of Molecular Bioactivity Related to the Cell Line

Cell Line
Protein
Compound

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Cell Line
Protein ID: PT06089, Axis inhibition protein 2
 Protein Info 
Compound ID Compound Name Compound Formula
CP0053018
 Compound Info 
2-(4-(Trifluoromethyl)phenyl)-7,8-dihydro-5H-thiopyrano-[4,3-d]pyrimidin-4-ol
   Show/Hide
C14H11F3N2OS
  1
1
EC50 = 371 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0056588
 Compound Info 
3-(3,4-dimethoxyphenyl)-5-[[4-(4-methoxyphenyl)-5-methyl-1,2,4-triazol-3-yl]sulfanylmethyl]-1,2,4-oxadiazole
   Show/Hide
C21H21N5O4S
  1
1
EC50 = 375 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0064177
 Compound Info 
5-[[4-(4-methoxyphenyl)-5-pyridin-4-yl-1,2,4-triazol-3-yl]sulfanylmethyl]-3-(4-methylphenyl)-1,2,4-oxadiazole
   Show/Hide
C24H20N6O2S
  1
1
EC50 = 566 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0070829
 Compound Info 
3-(4-methoxyphenyl)-5-[[4-(4-methoxyphenyl)-5-methyl-1,2,4-triazol-3-yl]sulfanylmethyl]-1,2,4-oxadiazole
   Show/Hide
C20H19N5O3S
  1
1
EC50 = 709 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
Protein ID: PT01975, Cyclin-dependent kinase 8
 Protein Info 
Protein ID: PT06109, Geminin
 Protein Info 
Protein ID: PT01425, Poly [ADP-ribose] polymerase tankyrase-2
 Protein Info 
Protein ID: PT03418, Protein Tat
 Protein Info 
Protein ID: PT02896, Tryptophan 2,3-dioxygenase
 Protein Info 
Cell Viability or Cytotoxicity Assay
Compound ID Compound Name Compound Formula
CP0017774
 Compound Info 
4-[[7-[2,6-bis(fluoranyl)phenyl]-9-chloranyl-5H-pyrimido[5,4-d][2]benzazepin-2-yl]amino]benzoic acid
   Show/Hide
 C25H15ClF2N4O2  1
1
IC50 = 860 nM
   TI
   LI
   LO
   TS
CP0075213
 Compound Info 
2-[3-[5-bromo-2-[4-[(3S)-3,4-dimethylpiperazin-1-yl]-3-methoxyanilino]pyrimidin-4-yl]phenyl]acetonitrile
   Show/Hide
 C25H27BrN6O  1
1
EC50 = 2225 nM
   TI
   LI
   LO
   TS
CP0139017
 Compound Info 
2-[10-(2-methoxyethyl)-13-oxa-3,4,6,7,10-pentazatricyclo[7.4.0.02,6]trideca-1(9),2,4,7-tetraen-5-yl]-N-(piperidin-4-ylmethyl)quinolin-8-amine
   Show/Hide
 C25H30N8O2  1
1
GI50 = 8170 nM
   TI
   LI
   LO
   TS
CP0148303
 Compound Info 
6,7-bis(3-morpholin-4-ylpropoxy)-N-[4-[(E)-prop-1-enyl]phenyl]quinazolin-4-amine
   Show/Hide
 C31H41N5O4  1
1
IC50 = 6080 nM
   TI
   LI
   LO
   TS
CP0237742
 Compound Info 
N-[1-[3-cyano-7-(cyclopropylamino)pyrazolo[1,5-a]pyrimidin-5-yl]indol-6-yl]acetamide
   Show/Hide
 C20H17N7O  1
1
GI50 = 1000 nM
   TI
   LI
   LO
   TS
CP0281834
 Compound Info 
N-[1-[3-cyano-7-(cyclopropylamino)pyrazolo[1,5-a]pyrimidin-5-yl]indazol-6-yl]acetamide
   Show/Hide
 C19H16N8O  1
1
GI50 = 5000 nM
   TI
   LI
   LO
   TS
CP0372605
 Compound Info 
(E)-1-[4-amino-3-(3,4-dimethoxyphenyl)phenyl]-3-(2,4-dimethoxyphenyl)prop-2-en-1-one
   Show/Hide
 C25H25NO5  1
1
IC50 = 9300 nM
   TI
   LI
   LO
   TS
CP0385531
 Compound Info 
CHEBI:67291
   Show/Hide
 C28H38O5  1
1
IC50 = 11200 nM
   TI
   LI
   LO
   TS
CP0417061
 Compound Info 
(E)-1-[4-amino-3-(3,4-dimethoxyphenyl)phenyl]-3-(2,3-dimethoxyphenyl)prop-2-en-1-one
   Show/Hide
 C25H25NO5  1
1
IC50 = 8330 nM
   TI
   LI
   LO
   TS
CP0420806
 Compound Info 
(5Z)-3-[4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butyl]-5-[(3,4-dimethoxyphenyl)methylidene]imidazolidine-2,4-dione
   Show/Hide
 C26H30Cl2N4O4  1
1
IC50 = 255470 nM
   TI
   LI
   LO
   TS
CP0420972
 Compound Info 
N-[3-[3-cyano-7-(cyclopropylamino)pyrazolo[1,5-a]pyrimidin-5-yl]-1-(2-hydroxyethyl)indol-5-yl]acetamide
   Show/Hide
 C22H21N7O2  1
1
GI50 = 4500 nM
   TI
   LI
   LO
   TS
CP0437743
 Compound Info 
N-(4-chlorophenyl)sulfonyl-2-methyl-2-[4-[2-(4-phenyldiazenylphenoxy)ethyl]phenoxy]propanamide
   Show/Hide
 C30H28ClN3O5S  1
1
CC50 > 24000 nM
   TI
   LI
   LO
   TS
CP0443743
 Compound Info 
N-[1-[3-cyano-7-[(1-methylpyrazol-3-yl)amino]pyrazolo[1,5-a]pyrimidin-5-yl]indol-6-yl]acetamide
   Show/Hide
 C21H17N9O  1
1
GI50 = 560 nM
   TI
   LI
   LO
   TS
CP0459790
 Compound Info 
(E)-1-[3-(3-fluorophenyl)phenyl]-3-(2-methoxyphenyl)prop-2-en-1-one
   Show/Hide
 C22H17FO2  1
1
IC50 = 16640 nM
   TI
   LI
   LO
   TS
CP0459792
 Compound Info 
(E)-1-[4-amino-3-(3,4-dimethoxyphenyl)phenyl]-3-(4-fluorophenyl)prop-2-en-1-one
   Show/Hide
 C23H20FNO3  1
1
IC50 = 14700 nM
   TI
   LI
   LO
   TS
CP0473305
 Compound Info 
2-methoxy-N-(6-morpholin-4-yl-7H-purin-2-yl)benzamide
   Show/Hide
 C17H18N6O3  1
1
IC50 = 14620 nM
   TI
   LI
   LO
   TS
CP0479178
 Compound Info 
5-chloro-N-[[4-(hydroxymethyl)phenyl]methyl]-1H-indole-3-carboxamide
   Show/Hide
 C17H15ClN2O2  1
1
IC50 = 16000 nM
   TI
   LI
   LO
   TS
CP0482075
 Compound Info 
N-[1-[3-cyano-7-(3-pyrrolidin-1-ylpropylamino)pyrazolo[1,5-a]pyrimidin-5-yl]indol-6-yl]acetamide
   Show/Hide
 C24H26N8O  1
1
GI50 = 13000 nM
   TI
   LI
   LO
   TS
CP0489848
 Compound Info 
N-[1-[3-cyano-7-(oxetan-3-ylamino)pyrazolo[1,5-a]pyrimidin-5-yl]indol-6-yl]acetamide
   Show/Hide
 C20H17N7O2  1
1
GI50 = 2500 nM
   TI
   LI
   LO
   TS
CP0497545
 Compound Info 
(E)-1-[3-(3-fluorophenyl)phenyl]-3-(4-methoxyphenyl)prop-2-en-1-one
   Show/Hide
 C22H17FO2  1
1
IC50 = 4510 nM
   TI
   LI
   LO
   TS
CP0497547
 Compound Info 
(E)-1-[4-amino-3-(4-fluorophenyl)phenyl]-3-(4-methoxyphenyl)prop-2-en-1-one
   Show/Hide
 C22H18FNO2  1
1
IC50 = 7230 nM
   TI
   LI
   LO
   TS
CP0497549
 Compound Info 
(E)-1-[4-amino-3-(4-fluorophenyl)phenyl]-3-(3-fluoro-4-hydroxyphenyl)prop-2-en-1-one
   Show/Hide
 C21H15F2NO2  1
1
IC50 = 31700 nM
   TI
   LI
   LO
   TS
CP0499661
 Compound Info 
(E)-1-[4-amino-3-(4-fluorophenyl)phenyl]-3-(4-hydroxy-3-methoxyphenyl)prop-2-en-1-one
   Show/Hide
 C22H18FNO3  1
1
IC50 = 8350 nM
   TI
   LI
   LO
   TS
CP0521661
 Compound Info 
7-(cyclopropylamino)-5-(4-methoxypyridin-3-yl)pyrazolo[1,5-a]pyrimidine-3-carbonitrile
   Show/Hide
 C16H14N6O  1
1
GI50 = 15000 nM
   TI
   LI
   LO
   TS
Protein family and CMB statistics Related to the Cell Line
Cell Lines Derived from the same Tissue Source (Colon)
Cell Line Name Organism Disease
HT-29
 Cell Line Info 
Homo sapiens (Human) Colon adenocarcinoma
Caco-2
 Cell Line Info 
Homo sapiens (Human) Colon adenocarcinoma
HCA7
 Cell Line Info 
Homo sapiens (Human) Colon adenocarcinoma
LS174T
 Cell Line Info 
Homo sapiens (Human) Colon adenocarcinoma
LS180
 Cell Line Info 
Homo sapiens (Human) Colon adenocarcinoma
SW1116
 Cell Line Info 
Homo sapiens (Human) Colon adenocarcinoma
WiDr
 Cell Line Info 
Homo sapiens (Human) Colon adenocarcinoma
S1-M1-80
 Cell Line Info 
Homo sapiens (Human) Colon adenocarcinoma
SW48
 Cell Line Info 
Homo sapiens (Human) Colon adenocarcinoma
S1
 Cell Line Info 
Homo sapiens (Human) Colon adenocarcinoma
Caco-2/TC-7
 Cell Line Info 
Homo sapiens (Human) Colon adenocarcinoma
COLO 320DM
 Cell Line Info 
Homo sapiens (Human) Colon adenocarcinoma
COLO 320
 Cell Line Info 
Homo sapiens (Human) Colon adenocarcinoma
HCT 116
 Cell Line Info 
Homo sapiens (Human) Colon carcinoma
RKO
 Cell Line Info 
Homo sapiens (Human) Colon carcinoma
KM12-Luc
 Cell Line Info 
Homo sapiens (Human) Colon carcinoma
TC71
 Cell Line Info 
Homo sapiens (Human) Colon carcinoma
KM12
 Cell Line Info 
Homo sapiens (Human) Colon carcinoma
KM12-L4A
 Cell Line Info 
Homo sapiens (Human) Colon carcinoma
HCA2
 Cell Line Info 
Homo sapiens (Human) Rectosigmoid adenocarcinoma
CT26
 Cell Line Info 
Mus musculus (Mouse) Mouse colon adenocarcinoma
51B LiM-1
 Cell Line Info 
Mus musculus (Mouse) Mouse colon adenocarcinoma
GLUTag
 Cell Line Info 
Mus musculus (Mouse) Neuroendocrine cell carcinoma of the mouse intestinal tract
CC531
 Cell Line Info 
Rattus norvegicus (Rat) Adenocarcinoma of the rat colon