General Information of the Cell Line
Cell Line ID
CL000171
Cell Line Name
SW1116
Synonyms
SW-1116
SW 1116
Category
Cancer cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_0544
Tissue Information
Colon
Disease
Colon adenocarcinoma (NCIt: C4349)
Map of Molecular Bioactivity Related to the Cell Line
Map of Molecular Bioactivity Related to the Cell Line

Cell Line
Protein
Compound

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Cell Line
Protein ID: PT01466, Telomerase reverse transcriptase
Compound ID Compound Name Compound Formula
CP0496031
2-(2,3-dihydro-1,4-benzodioxin-6-yl)-5-[(2-methylphenyl)methylsulfanyl]-1,3,4-oxadiazole
   Show/Hide
C18H16N2O3S
 1
1
IC50 = 1270 nM
   TI
   LI
   LO
   TS
CP0525019
2-[(4-bromophenyl)methylsulfanyl]-5-(2,3-dihydro-1,4-benzodioxin-6-yl)-1,3,4-oxadiazole
   Show/Hide
C17H13BrN2O3S
 1
1
IC50 = 1660 nM
   TI
   LI
   LO
   TS
CP0392064
2-(2,3-dihydro-1,4-benzodioxin-6-yl)-5-[(2-iodophenyl)methylsulfanyl]-1,3,4-oxadiazole
   Show/Hide
C17H13IN2O3S
 1
1
IC50 = 1830 nM
   TI
   LI
   LO
   TS
CP0461809
2-[(2-bromophenyl)methylsulfanyl]-5-(2,3-dihydro-1,4-benzodioxin-6-yl)-1,3,4-oxadiazole
   Show/Hide
C17H13BrN2O3S
 1
1
IC50 = 2020 nM
   TI
   LI
   LO
   TS
CP0459327
2-[(3-chlorophenyl)methylsulfanyl]-5-(2,3-dihydro-1,4-benzodioxin-6-yl)-1,3,4-oxadiazole
   Show/Hide
C17H13ClN2O3S
 1
1
IC50 = 2340 nM
   TI
   LI
   LO
   TS
CP0475434
2-[(2,4-difluorophenyl)methylsulfanyl]-5-(2,3-dihydro-1,4-benzodioxin-6-yl)-1,3,4-oxadiazole
   Show/Hide
C17H12F2N2O3S
 1
1
IC50 = 2440 nM
   TI
   LI
   LO
   TS
CP0475433
2-[(3-bromophenyl)methylsulfanyl]-5-(2,3-dihydro-1,4-benzodioxin-6-yl)-1,3,4-oxadiazole
   Show/Hide
C17H13BrN2O3S
 1
1
IC50 = 2450 nM
   TI
   LI
   LO
   TS
CP0525017
2-(2,3-dihydro-1,4-benzodioxin-6-yl)-5-[(4-nitrophenyl)methylsulfanyl]-1,3,4-oxadiazole
   Show/Hide
C17H13N3O5S
 1
1
IC50 = 2710 nM
   TI
   LI
   LO
   TS
CP0459326
2-[(4-chlorophenyl)methylsulfanyl]-5-(2,3-dihydro-1,4-benzodioxin-6-yl)-1,3,4-oxadiazole
   Show/Hide
C17H13ClN2O3S
 1
1
IC50 = 2910 nM
   TI
   LI
   LO
   TS
CP0418893
2-(2,3-dihydro-1,4-benzodioxin-6-yl)-5-[(2-fluorophenyl)methylsulfanyl]-1,3,4-oxadiazole
   Show/Hide
C17H13FN2O3S
 1
1
IC50 = 2930 nM
   TI
   LI
   LO
   TS
CP0394833
2-(2,3-dihydro-1,4-benzodioxin-6-yl)-5-[(3-methylphenyl)methylsulfanyl]-1,3,4-oxadiazole
   Show/Hide
C18H16N2O3S
 1
1
IC50 = 3260 nM
   TI
   LI
   LO
   TS
CP0513365
2-(2,3-dihydro-1,4-benzodioxin-6-yl)-5-[(4-iodophenyl)methylsulfanyl]-1,3,4-oxadiazole
   Show/Hide
C17H13IN2O3S
 1
1
IC50 = 3660 nM
   TI
   LI
   LO
   TS
CP0525018
2-(2,3-dihydro-1,4-benzodioxin-6-yl)-5-[(4-fluorophenyl)methylsulfanyl]-1,3,4-oxadiazole
   Show/Hide
C17H13FN2O3S
 1
1
IC50 = 3670 nM
   TI
   LI
   LO
   TS
CP0475432
2-(2,3-dihydro-1,4-benzodioxin-6-yl)-5-[(3-nitrophenyl)methylsulfanyl]-1,3,4-oxadiazole
   Show/Hide
C17H13N3O5S
 1
1
IC50 = 4650 nM
   TI
   LI
   LO
   TS
CP0394834
2-(2,3-dihydro-1,4-benzodioxin-6-yl)-5-[(4-methylphenyl)methylsulfanyl]-1,3,4-oxadiazole
   Show/Hide
C18H16N2O3S
 1
1
IC50 = 5040 nM
   TI
   LI
   LO
   TS
CP0522153
2-[(2-chlorophenyl)methylsulfanyl]-5-(2,3-dihydro-1,4-benzodioxin-6-yl)-1,3,4-oxadiazole
   Show/Hide
C17H13ClN2O3S
 1
1
IC50 = 5890 nM
   TI
   LI
   LO
   TS
CP0461807
2-benzylsulfanyl-5-(2,3-dihydro-1,4-benzodioxin-6-yl)-1,3,4-oxadiazole
   Show/Hide
C17H14N2O3S
 1
1
IC50 = 8210 nM
   TI
   LI
   LO
   TS
CP0004106
(2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-29-oxa-1,7,17-triazaoctacyclo[12.12.2.1^{2,6}.0^{7,28}.0^{8,13}.0^{15,19}.0^{20,27}.0^{21,26}]nonacosa-8(13),9,11,14(28),15(19),20(27),21(26),22,24-nonaen-16-one
   Show/Hide
C28H26N4O3
 1
1
IC50 = 8320 nM
   TI
   LI
   LO
   TS
CP0506093
2-(2,3-dihydro-1,4-benzodioxin-6-yl)-5-[(2-nitrophenyl)methylsulfanyl]-1,3,4-oxadiazole
   Show/Hide
C17H13N3O5S
 1
1
IC50 = 12150 nM
   TI
   LI
   LO
   TS
CP0513366
2-[(2,6-difluorophenyl)methylsulfanyl]-5-(2,3-dihydro-1,4-benzodioxin-6-yl)-1,3,4-oxadiazole
   Show/Hide
C17H12F2N2O3S
 1
1
IC50 = 15780 nM
   TI
   LI
   LO
   TS
Protein family and CMB statistics Related to the Cell Line
Cell Lines Derived from the same Tissue Source (Colon)
Cell Line Name Organism Disease
HT-29 Homo sapiens (Human) Colon adenocarcinoma
SW480 Homo sapiens (Human) Colon adenocarcinoma
Caco-2 Homo sapiens (Human) Colon adenocarcinoma
HCA7 Homo sapiens (Human) Colon adenocarcinoma
LS174T Homo sapiens (Human) Colon adenocarcinoma
LS180 Homo sapiens (Human) Colon adenocarcinoma
WiDr Homo sapiens (Human) Colon adenocarcinoma
S1-M1-80 Homo sapiens (Human) Colon adenocarcinoma
SW48 Homo sapiens (Human) Colon adenocarcinoma
S1 Homo sapiens (Human) Colon adenocarcinoma
Caco-2/TC-7 Homo sapiens (Human) Colon adenocarcinoma
COLO 320DM Homo sapiens (Human) Colon adenocarcinoma
COLO 320 Homo sapiens (Human) Colon adenocarcinoma
HCT 116 Homo sapiens (Human) Colon carcinoma
RKO Homo sapiens (Human) Colon carcinoma
KM12-Luc Homo sapiens (Human) Colon carcinoma
TC71 Homo sapiens (Human) Colon carcinoma
KM12 Homo sapiens (Human) Colon carcinoma
KM12-L4A Homo sapiens (Human) Colon carcinoma
HCA2 Homo sapiens (Human) Rectosigmoid adenocarcinoma
CT26 Mus musculus (Mouse) Mouse colon adenocarcinoma
51B LiM-1 Mus musculus (Mouse) Mouse colon adenocarcinoma
GLUTag Mus musculus (Mouse) Neuroendocrine cell carcinoma of the mouse intestinal tract
CC531 Rattus norvegicus (Rat) Adenocarcinoma of the rat colon