General Information of the Cell Line
Cell Line ID
CL000202
Cell Line Name
WiDr
Synonyms
WiDR
WIDR
WiDr/S
WiDr-TC
WiDrTC
LED-WiDr
Led-WiDr
Category
Cancer cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_2760
Tissue Information
Colon
Disease
Colon adenocarcinoma (NCIt: C4349)
Map of Molecular Bioactivity Related to the Cell Line
Map of Molecular Bioactivity Related to the Cell Line

Cell Line
Protein
Compound

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Cell Line
Protein ID: PT02429, Neurotensin receptor type 1
 Protein Info 
Compound ID Compound Name Compound Formula
CP0883489
 Compound Info 
Demotensin 1
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C48H85N17O10
  1
1
IC50 = 0.14 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0376388
 Compound Info 
(2S)-2-[[(2S,3S)-2-[[(2S)-2-[[(2S)-1-[(2S)-2-[[6-amino-2-[[2-[[3-(2-aminoethylamino)-2-[(2-aminoethylamino)methyl]propanoyl]amino]acetyl]amino]hexyl]amino]-5-(diaminomethylideneamino)pentanoyl]pyrrolidine-2-carbonyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]-3-methylpentanoyl]amino]-4-methylpentanoic acid
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C48H87N15O9
  1
1
IC50 = 0.18 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0064604
 Compound Info 
(2S)-2-[[(2S,3S)-2-[[(2S)-2-[[(2S)-1-[(2S)-2-[[(2S)-2-[[(2S)-1-[(2S)-6-amino-2-[[(2S)-4-amino-2-[[(2S)-4-carboxy-2-[[(2S)-3-(4-hydroxyphenyl)-2-[[(2S)-4-methyl-2-[[(2S)-5-oxopyrrolidine-2-carbonyl]amino]pentanoyl]amino]propanoyl]amino]butanoyl]amino]-4-oxobutanoyl]amino]hexanoyl]pyrrolidine-2-carbonyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]pyrrolidine-2-carbonyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]-3-methylpentanoyl]amino]-4-methylpentanoic acid
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C78H121N21O20
  1
1
IC50 = 0.46 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0058950
 Compound Info 
(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-1-[(2S)-2-[[2-[[2-[[3-(2-aminoethylamino)-2-[(2-aminoethylamino)methyl]propanoyl]amino]acetyl]amino]-5-(diaminomethylideneamino)pentyl]amino]-5-(diaminomethylideneamino)pentanoyl]pyrrolidine-2-carbonyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]-3,3-dimethylbutanoyl]amino]-4-methylpentanoic acid
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C48H87N17O9
  1
1
IC50 = 0.51 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0524385
 Compound Info 
(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-1-[(2S)-2-[[6-amino-2-[[2-[[3-(2-aminoethylamino)-2-[(2-aminoethylamino)methyl]propanoyl]amino]acetyl]amino]hexyl]amino]-5-(diaminomethylideneamino)pentanoyl]pyrrolidine-2-carbonyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]-3,3-dimethylbutanoyl]amino]-4-methylpentanoic acid
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C48H87N15O9
  1
1
IC50 = 0.66 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
Protein ID: PT04559, Splicing factor 3B subunit 3
 Protein Info 
Cell Viability or Cytotoxicity Assay
Compound ID Compound Name Compound Formula
CP0049207
 Compound Info 
(S)-2-{4-[3-(2,4-Diamino-6-oxo-1,6-dihydro-pyrimidin-5-yl)-propylamino]-benzoylamino}-pentanedioic acid
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 C19H24N6O6  1
1
IC50 = 45 nM
   TI
   LI
   LO
   TS
CP0154411
 Compound Info 
4-keto-8-nitro-1H-quinoline-3-carboxylic acid
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 C10H6N2O5  1
1
IC50 = 52600 nM
   TI
   LI
   LO
   TS
CP0845437
 Compound Info 
pladienolides D
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 C30H50O9  1
1
IC50 = 6 nM
   TI
   LI
   LO
   TS
CP0846153
 Compound Info 
pladienolide B
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 C30H50O8  1
1
IC50 = 0.86 nM
   TI
   LI
   LO
   TS
CP0849647
 Compound Info 
(3R,6R,7S,8E,10S,11S,12E,14E,16S,18R,19R,20R,21S)-3,6,21-trihydroxy-6,10,12,16,20-pentamethyl-7-{N-[(5S)-6-{N-methyl-N-[2-(N-methyl-N-{5-[(3aR,4R,6aS)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl]pentanoyl}amino)ethyl]amino}-6-oxo-5-(N-{4-[3-(trifluoromethyl)-3H-diaziren-3-yl]benzoyl}amino)hexyl]carbamoyloxy}-18,19-epoxytricosa-8,12,14-triene-11-olide
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 C58H87F3N8O12S  1
1
IC50 = 595 nM
   TI
   LI
   LO
   TS
CP0850965
 Compound Info 
(3R,6R,7S,8E,10S,11S,12E,14E,16R,18R,19R,20R,21S)-7-[(4-cycloheptylpiperazin-1-yl)carbonyl]oxy-3,6,16,21-tetrahydroxy-6,10,12,16,20-pentamethyl-18,19-epoyxtrichosa-8,12,14-trien-11-olide
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 C40H68N2O9  1
1
IC50 = 3.2 nM
   TI
   LI
   LO
   TS
CP0852132
 Compound Info 
(3R,6R,7S,8E,10S,11S,12E,14E,16S,18R,19R,20R,21S)-7-(N-[G-3H]-ethylcarbamoyloxy)-3,6,21-trihydroxy-6,10,12,16,20-pentamethyl-18,19-epoxytricosa-8,12,14-triene-11-olide
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 C31H53NO8  1
1
IC50 = 6.1 nM
   TI
   LI
   LO
   TS
Protein family and CMB statistics Related to the Cell Line
Cell Lines Derived from the same Tissue Source (Colon)
Cell Line Name Organism Disease
HT-29
 Cell Line Info 
Homo sapiens (Human) Colon adenocarcinoma
SW480
 Cell Line Info 
Homo sapiens (Human) Colon adenocarcinoma
Caco-2
 Cell Line Info 
Homo sapiens (Human) Colon adenocarcinoma
HCA7
 Cell Line Info 
Homo sapiens (Human) Colon adenocarcinoma
LS174T
 Cell Line Info 
Homo sapiens (Human) Colon adenocarcinoma
LS180
 Cell Line Info 
Homo sapiens (Human) Colon adenocarcinoma
SW1116
 Cell Line Info 
Homo sapiens (Human) Colon adenocarcinoma
S1-M1-80
 Cell Line Info 
Homo sapiens (Human) Colon adenocarcinoma
SW48
 Cell Line Info 
Homo sapiens (Human) Colon adenocarcinoma
S1
 Cell Line Info 
Homo sapiens (Human) Colon adenocarcinoma
Caco-2/TC-7
 Cell Line Info 
Homo sapiens (Human) Colon adenocarcinoma
COLO 320DM
 Cell Line Info 
Homo sapiens (Human) Colon adenocarcinoma
COLO 320
 Cell Line Info 
Homo sapiens (Human) Colon adenocarcinoma
HCT 116
 Cell Line Info 
Homo sapiens (Human) Colon carcinoma
RKO
 Cell Line Info 
Homo sapiens (Human) Colon carcinoma
KM12-Luc
 Cell Line Info 
Homo sapiens (Human) Colon carcinoma
TC71
 Cell Line Info 
Homo sapiens (Human) Colon carcinoma
KM12
 Cell Line Info 
Homo sapiens (Human) Colon carcinoma
KM12-L4A
 Cell Line Info 
Homo sapiens (Human) Colon carcinoma
HCA2
 Cell Line Info 
Homo sapiens (Human) Rectosigmoid adenocarcinoma
CT26
 Cell Line Info 
Mus musculus (Mouse) Mouse colon adenocarcinoma
51B LiM-1
 Cell Line Info 
Mus musculus (Mouse) Mouse colon adenocarcinoma
GLUTag
 Cell Line Info 
Mus musculus (Mouse) Neuroendocrine cell carcinoma of the mouse intestinal tract
CC531
 Cell Line Info 
Rattus norvegicus (Rat) Adenocarcinoma of the rat colon