Brief Information of the Cell Line and Protein
Cell Line ID: CL000202 , WiDr
 Cell Line Info 
Synonyms
WiDR
WIDR
WiDr/S
WiDr-TC
WiDrTC
LED-WiDr
Led-WiDr
Category Cancer cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_2760
Protein ID: PT04559 , Splicing factor 3B subunit 3
 Protein Info 
Gene Name SF3B3
Organism Homo sapiens, Human
Protein Classification Other nuclear protein
Uniprot ID Q15393
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000202
 Cell Line Info 
 Protein ID: PT04559
 Protein Info 
 
Compound ID Compound Name Compound Formula
CP0846153
 Compound Info 
pladienolide B
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C30H50O8
  1
1
IC50 = 1 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0850965
 Compound Info 
(3R,6R,7S,8E,10S,11S,12E,14E,16R,18R,19R,20R,21S)-7-[(4-cycloheptylpiperazin-1-yl)carbonyl]oxy-3,6,16,21-tetrahydroxy-6,10,12,16,20-pentamethyl-18,19-epoyxtrichosa-8,12,14-trien-11-olide
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C40H68N2O9
  1
1
IC50 = 3.2 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0845437
 Compound Info 
pladienolides D
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C30H50O9
  1
1
IC50 = 4.3 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0852132
 Compound Info 
(3R,6R,7S,8E,10S,11S,12E,14E,16S,18R,19R,20R,21S)-7-(N-[G-3H]-ethylcarbamoyloxy)-3,6,21-trihydroxy-6,10,12,16,20-pentamethyl-18,19-epoxytricosa-8,12,14-triene-11-olide
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C31H53NO8
  1
1
IC50 = 4.9 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0852133
 Compound Info 
pladienolide C
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C30H48O8
  1
1
IC50 = 7.4 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0666814
 Compound Info 
FK-506
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C44H69NO12
  1
1
IC50 = 10.9 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0849646
 Compound Info 
pladienolide E
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C30H50O9
  1
1
IC50 = 65.2 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0849645
 Compound Info 
pladienolide A
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C28H48O7
  1
1
IC50 = 418.1 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0005479
 Compound Info 
CHEBI:46024
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C17H22N2O3
  1
1
IC50 = 577.6 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0877427
 Compound Info 
pladienolide F
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C28H48O8
  1
1
IC50 = 2894.2 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0009077
 Compound Info 
LACTACYSTIN
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C15H24N2O7S
  1
1
IC50 > 10000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS