Brief Information of the Compound and Protein
Compound Name
FK-506
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PubChem ID
CID: 445643
SID: 14889261
Canonical SMILES
C=CC[C@@H]1/C=C(\C)C[C@H](C)C[C@H](OC)[C@H]2O[C@@](O)(C(=O)C(=O)N3CCCC[C@H]3C(=O)O[C@H](/C(C)=C/[C@@H]3CC[C@@H](O)[C@H](OC)C3)[C@H](C)[C@@H](O)CC1=O)[C@H](C)C[C@@H]2OC
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Compound Formula C44H69NO12
Compound Structure
Protein Name
Splicing factor 3B subunit 3
Protein Classification
Other nuclear protein
Uniprot ID
Q15393
Gene Name
SF3B3
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000118 U-251MG Homo sapiens (Human)  1
1
IC50 = 13.8 nM
   TI
   LI
   LO
   TS
CL000202 WiDr Homo sapiens (Human)  1
1
IC50 = 10.9 nM
   TI
   LI
   LO
   TS