General Information of the Cell Line
Cell Line ID
CL000046
Cell Line Name
HCA7
Synonyms
HCA-7
HCA 7
Category
Cancer cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_0289
Tissue Information
Colon
Disease
Colon adenocarcinoma (NCIt: C4349)
Map of Molecular Bioactivity Related to the Cell Line
Map of Molecular Bioactivity Related to the Cell Line

Cell Line
Protein
Compound

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Cell Line
Protein ID: PT00915, Peroxisome proliferator-activated receptor gamma
 Protein Info 
Compound ID Compound Name Compound Formula
CP0090691
 Compound Info 
(E)-2-(5-Fluoro-1-((4-fluoronaphthalen-1-yl)methylene)-1H-inden-3-yl)ethanoic acid
   Show/Hide
C22H14F2O2
  1
1
EC50 = 100 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0090696
 Compound Info 
(E)-2-(1-(Biphenyl-4-ylmethylene)-5-fluoro-1H-inden-3-yl)ethanoic acid
   Show/Hide
C24H17FO2
  1
1
EC50 = 100 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0091520
 Compound Info 
(E)-2-(5-Fluoro-1-(naphthalen-1-ylmethylene)-1H-inden-3-yl)-ethanoic acid
   Show/Hide
C22H15FO2
  1
1
EC50 = 100 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0137439
 Compound Info 
(E)-2-(1-((2,4-Difluorobiphenyl-4-yl)methylene)-5-fluoro-1H-inden-3-yl)ethanoic acid
   Show/Hide
C24H15F3O2
  1
1
EC50 = 100 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0091522
 Compound Info 
(E)-2-(5-Fluoro-1-(4-(trifluoromethylthio)benzylidene)-1H-inden-3-yl)ethanoic acid
   Show/Hide
C19H12F4O2S
  1
1
EC50 = 200 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0090694
 Compound Info 
(E)-2'-des-methyl sulindac sulfide
   Show/Hide
C19H15FO2S
  1
1
EC50 = 700 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0000254
 Compound Info 
(Z)-2-(3-(4-(methylthio)benzylidene)-6-fluoro-2-methyl-3H-inden-1-yl)acetic acid
   Show/Hide
C20H17FO2S
  1
1
EC50 = 800 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0090698
 Compound Info 
(E)-2-(1-(4-(Azidomethyl)benzylidene)-5-fluoro-1H-inden-3-yl)-ethanoic acid
   Show/Hide
C19H14FN3O2
  1
1
EC50 = 900 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0090699
 Compound Info 
(E)-2-(1-(4-Ethynylbenzylidene)-5-fluoro-1H-inden-3-yl)ethanoicacid
   Show/Hide
C20H13FO2
  1
1
EC50 = 1100 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0091523
 Compound Info 
(E)-2-(1-(4-Bromobenzylidene)-5-fluoro-1H-inden-3-yl)ethanoicacid
   Show/Hide
C18H12BrFO2
  1
1
EC50 = 1100 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0193004
 Compound Info 
(E)-2-(5-Fluoro-1-(naphthalen-2-ylmethylene)-1H-inden-3-yl)-ethanoic acid
   Show/Hide
C22H15FO2
  1
1
EC50 = 1200 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0193005
 Compound Info 
(E)-2-(5-Fluoro-1-(4-methoxybenzylidene)-1H-inden-3-yl)ethanoicacid
   Show/Hide
C19H15FO3
  1
1
EC50 = 1300 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0090690
 Compound Info 
(E)-2-(5-Fluoro-1-((4-(methylthio)biphenyl-4-yl)methylene)-1Hinden-3-yl)ethanoic acid
   Show/Hide
C25H19FO2S
  1
1
EC50 = 1500 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0158929
 Compound Info 
(E)-2-(5-Fluoro-1-(quinolin-8-ylmethylene)-1H-inden-3-yl)ethanoicacid
   Show/Hide
C21H14FNO2
  1
1
EC50 = 1500 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0090692
 Compound Info 
(E)-2-(1-Benzylidene-5-fluoro-1H-inden-3-yl)ethanoic acid
   Show/Hide
C18H13FO2
  1
1
EC50 = 1700 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0167793
 Compound Info 
(E)-2-(1-(4-tert-Butoxybenzylidene)-5-fluoro-1H-inden-3-yl)ethanoicacid
   Show/Hide
C22H21FO3
  1
1
EC50 = 1900 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0163947
 Compound Info 
(E)-2-(5-Fluoro-1-(4-methylbenzylidene)-1H-inden-3-yl)ethanoicacid
   Show/Hide
C19H15FO2
  1
1
EC50 = 2400 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0193007
 Compound Info 
(E)-2-(5-Fluoro-1-(4-(trifluoromethyl)benzylidene)-1H-inden-3-yl)ethanoic acid
   Show/Hide
C19H12F4O2
  1
1
EC50 = 2500 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0090700
 Compound Info 
2-(5-Fluoro-1H-inden-3-yl)ethanoic acid
   Show/Hide
C11H9FO2
  1
1
EC50 > 10000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0134572
 Compound Info 
(E)-2-(5-Fluoro-1-(4-(methylsulfonyl)benzylidene)-1H-inden-3-yl)ethanoic acid
   Show/Hide
C19H15FO4S
  1
1
EC50 > 10000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0137436
 Compound Info 
(E)-4-((3-(Carboxymethyl)-5-fluoro-1H-inden-1-ylidene)methyl)-benzoic acid
   Show/Hide
C19H13FO4
  1
1
EC50 > 10000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0137440
 Compound Info 
(E)-2-(5-Fluoro-1-(quinoxalin-6-ylmethylene)-1H-inden-3-yl)-ethanoic acid
   Show/Hide
C20H13FN2O2
  1
1
EC50 > 10000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0230435
 Compound Info 
(E)-2-(5-Fluoro-1-(4-(methylsulfinyl)benzylidene)-1H-inden-3-yl)ethanoic acid
   Show/Hide
C19H15FO3S
  1
1
EC50 > 10000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
Protein family and CMB statistics Related to the Cell Line
Cell Lines Derived from the same Tissue Source (Colon)
Cell Line Name Organism Disease
HT-29
 Cell Line Info 
Homo sapiens (Human) Colon adenocarcinoma
SW480
 Cell Line Info 
Homo sapiens (Human) Colon adenocarcinoma
Caco-2
 Cell Line Info 
Homo sapiens (Human) Colon adenocarcinoma
LS174T
 Cell Line Info 
Homo sapiens (Human) Colon adenocarcinoma
LS180
 Cell Line Info 
Homo sapiens (Human) Colon adenocarcinoma
SW1116
 Cell Line Info 
Homo sapiens (Human) Colon adenocarcinoma
WiDr
 Cell Line Info 
Homo sapiens (Human) Colon adenocarcinoma
S1-M1-80
 Cell Line Info 
Homo sapiens (Human) Colon adenocarcinoma
SW48
 Cell Line Info 
Homo sapiens (Human) Colon adenocarcinoma
S1
 Cell Line Info 
Homo sapiens (Human) Colon adenocarcinoma
Caco-2/TC-7
 Cell Line Info 
Homo sapiens (Human) Colon adenocarcinoma
COLO 320DM
 Cell Line Info 
Homo sapiens (Human) Colon adenocarcinoma
COLO 320
 Cell Line Info 
Homo sapiens (Human) Colon adenocarcinoma
HCT 116
 Cell Line Info 
Homo sapiens (Human) Colon carcinoma
RKO
 Cell Line Info 
Homo sapiens (Human) Colon carcinoma
KM12-Luc
 Cell Line Info 
Homo sapiens (Human) Colon carcinoma
TC71
 Cell Line Info 
Homo sapiens (Human) Colon carcinoma
KM12
 Cell Line Info 
Homo sapiens (Human) Colon carcinoma
KM12-L4A
 Cell Line Info 
Homo sapiens (Human) Colon carcinoma
HCA2
 Cell Line Info 
Homo sapiens (Human) Rectosigmoid adenocarcinoma
CT26
 Cell Line Info 
Mus musculus (Mouse) Mouse colon adenocarcinoma
51B LiM-1
 Cell Line Info 
Mus musculus (Mouse) Mouse colon adenocarcinoma
GLUTag
 Cell Line Info 
Mus musculus (Mouse) Neuroendocrine cell carcinoma of the mouse intestinal tract
CC531
 Cell Line Info 
Rattus norvegicus (Rat) Adenocarcinoma of the rat colon