General Information of the Cell Line
Cell Line ID
CL000007
Cell Line Name
HT-29
Synonyms
HT 29
HT29
Category
Cancer cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_0320
Tissue Information
Colon
Disease
Colon adenocarcinoma (NCIt: C4349)
Map of Molecular Bioactivity Related to the Cell Line
Map of Molecular Bioactivity Related to the Cell Line

Cell Line
Protein
Compound

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Cell Line
Protein ID: PT01223, Aurora kinase B
 Protein Info 
Compound ID Compound Name Compound Formula
CP0029006
 Compound Info 
4-[4-[7-amino-2-(1,2,3-benzothiadiazol-7-yl)furo[2,3-c]pyridin-4-yl]pyrazol-1-yl]cyclohexan-1-ol
   Show/Hide
C22H20N6O2S
  1
1
IC50 = 160 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0043422
 Compound Info 
4-[6-amino-7-[(1R)-1-(2,6-dichloro-3-fluorophenyl)ethoxy]furo[3,2-c]pyridin-3-yl]-3,6-dihydro-2H-pyridine-1-carboxamide
   Show/Hide
C21H19Cl2FN4O3
  2
1
IC50 = 1000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
2
IC50 > 10000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0017901
 Compound Info 
4-[4-[7-amino-2-(1,2,3-benzothiadiazol-7-yl)-3-(fluoromethyl)furo[2,3-c]pyridin-4-yl]pyrazol-1-yl]cyclohexan-1-ol
   Show/Hide
C23H21FN6O2S
  1
1
IC50 = 1500 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0018196
 Compound Info 
4-[4-[7-amino-2-(1,2,3-benzothiadiazol-7-yl)-3-(difluoromethyl)furo[2,3-c]pyridin-4-yl]pyrazol-1-yl]cyclohexan-1-ol
   Show/Hide
C23H20F2N6O2S
  1
1
IC50 = 1700 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0018308
 Compound Info 
4-[4-[7-amino-2-(1,2,3-benzothiadiazol-7-yl)-3-(1,3-thiazol-5-yl)furo[2,3-c]pyridin-4-yl]pyrazol-1-yl]cyclohexan-1-ol
   Show/Hide
C25H21N7O2S2
  1
1
IC50 = 1700 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0029005
 Compound Info 
4-(1-methylpyrazol-4-yl)-2-thieno[2,3-c]pyridin-3-ylfuro[2,3-c]pyridin-7-amine
   Show/Hide
C18H13N5OS
  1
1
IC50 = 3000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0018592
 Compound Info 
4-[4-[7-amino-2-(1,2,3-benzothiadiazol-7-yl)-3-chlorofuro[2,3-c]pyridin-4-yl]pyrazol-1-yl]cyclohexan-1-ol
   Show/Hide
C22H19ClN6O2S
  1
1
IC50 = 6500 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0018195
 Compound Info 
4-[4-[7-amino-2-(1,2,3-benzothiadiazol-7-yl)-3-pyridin-3-ylfuro[2,3-c]pyridin-4-yl]pyrazol-1-yl]cyclohexan-1-ol
   Show/Hide
C27H23N7O2S
  1
1
IC50 = 6900 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0025123
 Compound Info 
7-amino-2-(1,2,3-benzothiadiazol-7-yl)-4-[1-(4-hydroxycyclohexyl)pyrazol-4-yl]furo[2,3-c]pyridine-3-carbonitrile
   Show/Hide
C23H19N7O2S
  1
1
IC50 > 10000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0031772
 Compound Info 
4-(1,5-dimethylpyrazol-4-yl)-2-thieno[2,3-c]pyridin-3-ylfuro[2,3-c]pyridin-7-amine
   Show/Hide
C19H15N5OS
  1
1
IC50 = 17400 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0031773
 Compound Info 
4-(1,3-dimethylpyrazol-4-yl)-2-thieno[2,3-c]pyridin-3-ylfuro[2,3-c]pyridin-7-amine
   Show/Hide
C19H15N5OS
  1
1
IC50 > 20000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0031774
 Compound Info 
4-(3-methoxy-1-methylpyrazol-4-yl)-2-thieno[2,3-c]pyridin-3-ylfuro[2,3-c]pyridin-7-amine
   Show/Hide
C19H15N5O2S
  1
1
IC50 > 20000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0020413
 Compound Info 
2,4-Bisanilinopyrimidine, 9
   Show/Hide
C31H29ClFN7O3
  1
1
IC50 > 27000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0037005
 Compound Info 
2,4-Bisanilinopyrimidine, 10
   Show/Hide
C31H31ClFN7O2
  1
1
IC50 > 27000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0024021
 Compound Info 
2,4-Bisanilinopyrimidine, 13
   Show/Hide
C23H17ClFN5O2
  1
1
IC50 > 30000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0253748
 Compound Info 
2,4-Bisanilinopyrimidine, 14
   Show/Hide
C20H18FN5O2
  1
1
IC50 > 30000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0298941
 Compound Info 
2,4-Bisanilinopyrimidine, 5
   Show/Hide
C23H17ClFN5O2
  1
1
IC50 > 30000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
Protein ID: PT07381, Alpha-1-antitrypsin-related protein
 Protein Info 
Protein ID: PT01650, Alpha-2A adrenergic receptor
 Protein Info 
Protein ID: PT02059, C-X-C chemokine receptor type 4
 Protein Info 
Protein ID: PT00926, Cyclin-dependent kinase 1
 Protein Info 
Protein ID: PT01014, Cysteine protease CPP32
 Protein Info 
Protein ID: PT02536, Diacylglycerol O-acyltransferase 1
 Protein Info 
Protein ID: PT00955, DNA-dependent protein kinase catalytic subunit
 Protein Info 
Protein ID: PT00922, Epidermal growth factor receptor
 Protein Info 
Protein ID: PT01141, Focal adhesion kinase 1
 Protein Info 
Protein ID: PT04427, Free fatty acid receptor 4
 Protein Info 
Protein ID: PT03308, G-protein coupled receptor 35
 Protein Info 
Protein ID: PT03550, Interleukin-17A
 Protein Info 
Protein ID: PT00933, Macrophage-stimulating protein receptor
 Protein Info 
Protein ID: PT02429, Neurotensin receptor type 1
 Protein Info 
Protein ID: PT04124, Proteinase-activated receptor 2
 Protein Info 
Protein ID: PT00845, RAC-alpha serine/threonine-protein kinase
 Protein Info 
Protein ID: PT00954, Receptor-interacting protein 1
 Protein Info 
Protein ID: PT01902, Serine-protein kinase ATM
 Protein Info 
Protein ID: PT01934, Serine/threonine-protein kinase ATR
 Protein Info 
Protein ID: PT01381, Serine/threonine-protein kinase B-raf
 Protein Info 
Protein ID: PT00865, Serine/threonine-protein kinase Chk1
 Protein Info 
Protein ID: PT03805, Sodium/hydrogen exchanger 1
 Protein Info 
Protein ID: PT01466, Telomerase reverse transcriptase
 Protein Info 
Protein ID: PT01361, Vasoactive intestinal polypeptide receptor 1
 Protein Info 
Cell Viability or Cytotoxicity Assay
Compound ID Compound Name Compound Formula
CP0003317
 Compound Info 
(E)-N-hydroxy-3-[4-[2-[(E)-2-(2-methyl-1H-indol-3-yl)ethenyl]phenyl]phenyl]prop-2-enamide
   Show/Hide
 C26H22N2O2  1
1
IC50 = 2440 nM
   TI
   LI
   LO
   TS
CP0003580
 Compound Info 
Faridak
   Show/Hide
 C21H23N3O2  1
1
IC50 = 37.55 nM
   TI
   LI
   LO
   TS
CP0006369
 Compound Info 
6-[3-[4-[1-(5-cyanopentyl)indol-3-yl]-1-hydroxy-2,5-dioxopyrrol-3-yl]indol-1-yl]hexanenitrile
   Show/Hide
 C32H31N5O3  1
1
LC50 > 100000 nM
   TI
   LI
   LO
   TS
CP0007711
 Compound Info 
(E)-3-[4-[[2-(2-methyl-1H-indol-3-yl)ethylamino]methyl]phenyl]-N'-propylprop-2-enehydrazide;2,2,2-trifluoroacetic acid
   Show/Hide
 C26H31F3N4O3  1
1
GI50 = 32.4 nM
   TI
   LI
   LO
   TS
CP0013685
 Compound Info 
8-[5-(difluoromethyl)pyridin-3-yl]-1-(2,3,6,7-tetrahydrooxepin-4-yl)-[1,2,4]triazolo[4,3-a]quinoxaline
   Show/Hide
 C21H17F2N5O  1
1
IC50 = 2540 nM
   TI
   LI
   LO
   TS
CP0015738
 Compound Info 
(1S,4S,7Z,10S,16E,21R)-7-ethylidene-4,21-bis(propan-2-yl)-2-oxa-12,13-dithia-5,8,20,23-tetraazabicyclo[8.7.6]tricos-16-ene-3,6,9,19,22-pentone
   Show/Hide
 C24H36N4O6S2  1
1
GI50 = 3.3 nM
   TI
   LI
   LO
   TS
CP0018963
 Compound Info 
3-(4-{4-aminofuro[2,3-d]pyrimidin-5-yl}phenyl)-1-[2-fluoro-5-(trifluoromethyl)phenyl]urea
   Show/Hide
 C20H13F4N5O2  1
1
IC50 = 5084 nM
   TI
   LI
   LO
   TS
CP0019438
 Compound Info 
8-[3-(1-benzothiophen-2-yl)-5-chloropyridin-4-yl]-2,8-diazaspiro[4.5]decan-1-one
   Show/Hide
 C21H20ClN3OS  1
1
GI50 = 29280 nM
   TI
   LI
   LO
   TS
CP0019439
 Compound Info 
8-[3-(1-benzofuran-2-yl)-5-chloropyridin-4-yl]-2,8-diazaspiro[4.5]decan-1-one
   Show/Hide
 C21H20ClN3O2  1
1
GI50 = 44250 nM
   TI
   LI
   LO
   TS
CP0031182
 Compound Info 
Anilinoquinazoline deriv. 9
   Show/Hide
 C16H13ClFN3O2  1
1
IC50 = 5700 nM
   TI
   LI
   LO
   TS
CP0034470
 Compound Info 
(-)-combretastatin
   Show/Hide
 C18H20O5  1
1
IC50 = 720 nM
   TI
   LI
   LO
   TS
CP0036044
 Compound Info 
(+/-)-6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide
   Show/Hide
 C13H13ClN2O  1
1
IC50 > 100000 nM
   TI
   LI
   LO
   TS
CP0036082
 Compound Info 
N-(3-chloro-4-fluorophenyl)-7-methoxy-6-(3-morpholin-4-ylpropoxy)quinazolin-4-amine
   Show/Hide
 C22H24ClFN4O3  1
1
IC50 = 9800 nM
   TI
   LI
   LO
   TS
CP0036972
 Compound Info 
4-(2-chlorophenyl)-9-hydroxy-6-methyl-8-(3-pyrrolidin-1-ylpropoxy)pyrrolo[3,4-c]carbazole-1,3-dione
   Show/Hide
 C28H26ClN3O4  1
1
IC50 = 310 nM
   TI
   LI
   LO
   TS
CP0037781
 Compound Info 
3-[3-(azetidin-1-ylmethyl)cyclobutyl]-1-(2-phenylquinolin-7-yl)imidazo[1,5-a]pyrazin-8-amine
   Show/Hide
 C29H28N6  1
1
IC50 = 1260 nM
   TI
   LI
   LO
   TS
CP0038067
 Compound Info 
(S)-N-(1-(3-fluorobenzyl)-1H-indazol-5-yl)-5-((morpholin-2-ylmethoxy)methyl)pyrrolo[1,2-f][1,2,4]triazin-4-amine
   Show/Hide
 C26H26FN7O2  1
1
IC50 = 8700 nM
   TI
   LI
   LO
   TS
CP0039971
 Compound Info 
NSC-114945
   Show/Hide
 C30H48O3  1
1
LD50 = 180000 nM
   TI
   LI
   LO
   TS
CP0040472
 Compound Info 
tert-butyl 4-[6-(4-aminophenyl)-4-morpholin-4-ylpyrazolo[3,4-d]pyrimidin-1-yl]piperidine-1-carboxylate
   Show/Hide
 C25H33N7O3  1
1
IC50 = 3000 nM
   TI
   LI
   LO
   TS
CP0047127
 Compound Info 
5-chloro-N-(2-chloro-4-nitrophenyl)-2-hydroxybenzamide
   Show/Hide
 C13H8Cl2N2O4  1
1
IC50 = 7200 nM
   TI
   LI
   LO
   TS
CP0052751
 Compound Info 
diethyl 4-(4-chlorophenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate
   Show/Hide
 C19H22ClNO4  1
1
IC50 = 261700 nM
   TI
   LI
   LO
   TS
CP0057464
 Compound Info 
(2S)-2-(4-{2-[1,3-benzoxazol-2-yl(heptyl)amino]ethyl}phenoxy)-2-methylbutanoic acid
   Show/Hide
 C27H36N2O4  1
1
IC50 = 50000 nM
   TI
   LI
   LO
   TS
CP0058804
 Compound Info 
12-[4-(piperidin-1-ylmethyl)phenyl]-5,8,10-triazatricyclo[7.4.0.02,7]trideca-1(9),2(7),3,5,10,12-hexaene-4-carbonitrile
   Show/Hide
 C23H21N5  1
1
GI50 = 8700 nM
   TI
   LI
   LO
   TS
CP0064592
 Compound Info 
[(1S,2S,3R,4S,7R,9S,10S,12R,15S)-4,12-diacetyloxy-15-[(2R,3S)-3-benzamido-2-hydroxy-3-phenylpropanoyl]oxy-1,9-dihydroxy-10,14,17,17-tetramethyl-11-oxo-6-oxatetracyclo[11.3.1.03,10.04,7]heptadec-13-en-2-yl] benzoate
   Show/Hide
 C47H51NO14  1
1
GI50 = 5 nM
   TI
   LI
   LO
   TS
CP0068085
 Compound Info 
2-chloro-N-(4-chloro-3-(pyridin-2-yl)phenyl)-4-(methylsulfonyl)benzamide
   Show/Hide
 C19H14Cl2N2O3S  1
1
IC50 = 1080 nM
   TI
   LI
   LO
   TS
CP0071290
 Compound Info 
9-chloro-2-[[5-[3-(dimethylamino)propyl]-2-methylpyridin-3-yl]amino]-5,7-dihydropyrimido[5,4-d][1]benzazepine-6-thione
   Show/Hide
 C23H25ClN6S  1
1
LD50 = 17000 nM
   TI
   LI
   LO
   TS
CP0076082
 Compound Info 
N-(6-methyl-1,3-benzothiazol-2-yl)-2-[(4-oxo-3-phenyl-6,7-dihydrothieno[3,2-d]pyrimidin-2-yl)sulfanyl]acetamide
   Show/Hide
 C22H18N4O2S3  1
1
EC50 = 4670 nM
   TI
   LI
   LO
   TS
CP0078293
 Compound Info 
N-[(9R)-4-(3H-imidazo[4,5-c]pyridin-2-yl)-9H-fluoren-9-yl]-1H-pyrrolo[2,3-b]pyridine-4-carboxamide
   Show/Hide
 C27H18N6O  1
1
IC50 = 20 nM
   TI
   LI
   LO
   TS
CP0082019
 Compound Info 
(2R)-2-amino-3-[(triphenylmethyl)sulfanyl]propanoic acid
   Show/Hide
 C22H21NO2S  1
1
GI50 = 3980 nM
   TI
   LI
   LO
   TS
CP0083030
 Compound Info 
11H-2,5,11-triaza-benzo[a]trindene-1,3,4,6-tetraone
   Show/Hide
 C16H7N3O4  1
1
IC50 = 9700 nM
   TI
   LI
   LO
   TS
CP0090639
 Compound Info 
N-benzyl-2-[2-[methyl(5-pyrrolidin-1-ylpentyl)amino]-3-(4-phenylphenyl)-4H-quinazolin-4-yl]acetamide
   Show/Hide
 C39H45N5O  1
1
GI50 = 610 nM
   TI
   LI
   LO
   TS
CP0103138
 Compound Info 
4-(2-chlorophenyl)-8-(3-(dimethylamino)propoxy)-9-hydroxy-6-methylpyrrolo[3,4-c]carbazole-1,3(2H,6H)-dione
   Show/Hide
 C26H24ClN3O4  1
1
IC50 = 230 nM
   TI
   LI
   LO
   TS
CP0124520
 Compound Info 
(1S,5S,6R,9S,15E,20R)-5-hydroxy-20-(2-methylsulfanylethyl)-6-propan-2-yl-2-oxa-11,12-dithia-7,19,22-triazabicyclo[7.7.6]docos-15-ene-3,8,18,21-tetrone
   Show/Hide
 C22H35N3O6S3  1
1
GI50 = 0.65 nM
   TI
   LI
   LO
   TS
CP0127573
 Compound Info 
N-hydroxy-4-[(3-methyl-2-phenylbutanoyl)amino]benzamide
   Show/Hide
 C18H20N2O3  1
1
IC50 = 600 nM
   TI
   LI
   LO
   TS
CP0128439
 Compound Info 
2-Amino-N-(2-aminoethyl)-5-(2,3-dihydrothieno[3,4-b][1,4]dioxin-5-yl)nicotinamide
   Show/Hide
 C14H16N4O3S  1
1
GI50 = 28000 nM
   TI
   LI
   LO
   TS
CP0135381
 Compound Info 
4-hexyl-11-methyl-1H-furo[3,4-b]oxanthren-3-one
   Show/Hide
 C21H22O4  1
1
IC50 = 1330 nM
   TI
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CP0142470
 Compound Info 
US10266537, Compound 93
   Show/Hide
 C29H27F3N6O2  1
1
IC50 = 231 nM
   TI
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CP0144722
 Compound Info 
4,7-dihydroxybenzo[a]pyrrolo[3,4-c]carbazole-1,3(2H,8H)-dione
   Show/Hide
 C18H10N2O4  1
1
IC50 = 5600 nM
   TI
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   TS
CP0145292
 Compound Info 
4-methyl-N-[4-[(1-methylpiperidin-4-yl)methoxy]-3-(trifluoromethyl)phenyl]-3-[[1-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)cyclopropanecarbonyl]amino]benzamide
   Show/Hide
 C32H33F3N6O3  1
1
IC50 = 2200 nM
   TI
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   TS
CP0145317
 Compound Info 
9-chloro-2-[[5-[3-(dimethylamino)propyl]pyridin-3-yl]amino]-5,7-dihydropyrimido[5,4-d][1]benzazepine-6-thione
   Show/Hide
 C22H23ClN6S  1
1
LD50 = 34000 nM
   TI
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   TS
CP0148456
 Compound Info 
(2R)-2-amino-3-[(4-methoxyphenyl)-diphenylmethyl]sulfanylpropan-1-ol
   Show/Hide
 C23H25NO2S  1
1
GI50 = 340 nM
   TI
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   TS
CP0151098
 Compound Info 
N-(3-chloro-4-fluorophenyl)-7-[2-(diethylamino)ethoxy]-6-methoxyquinazolin-4-amine
   Show/Hide
 C21H24ClFN4O2  1
1
IC50 = 5900 nM
   TI
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   TS
CP0157630
 Compound Info 
N-cyclopropyl-4-[7-[(3-hydroxy-3-methylcyclobutyl)methylamino]-5-pyridin-3-yloxypyrazolo[1,5-a]pyrimidin-3-yl]-2-methylbenzamide
   Show/Hide
 C28H30N6O3  1
1
IC50 = 557 nM
   TI
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   TS
CP0159148
 Compound Info 
5-[(3-hydroxypropyl)sulfanyl]-3-methyl-1-(2-methylpropyl)-6-(naphthalen-1-ylmethyl)-1H,2H,3H,4H-thieno[2,3-d]pyrimidine-2,4-dione
   Show/Hide
 C25H28N2O3S2  1
1
IC50 > 1000 nM
   TI
   LI
   LO
   TS
CP0165922
 Compound Info 
N-[3-[3-[4-[(dimethylamino)methyl]phenyl]pyrazolo[1,5-a]pyrimidin-7-yl]phenyl]-3-(trifluoromethyl)benzamide
   Show/Hide
 C29H24F3N5O  1
1
IC50 = 920 nM
   TI
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CP0166540
 Compound Info 
N-benzyl-2-[5-[4-(2-morpholin-4-ylethoxy)phenyl]pyridin-2-yl]acetamide
   Show/Hide
 C26H29N3O3  2
1
GI50 = 25 nM
   TI
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   TS
2
IC50 = 5 nM
   TI
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CP0171017
 Compound Info 
1-(3-chloro-4-fluorophenyl)-3-(4-(6,7-dimethoxyquinazolin-4-ylamino)phenyl)urea
   Show/Hide
 C23H19ClFN5O3  1
1
IC50 = 6200 nM
   TI
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   TS
CP0176598
 Compound Info 
N-[4-[2-[(2S,3S,5R)-2-[[tert-butyl(dimethyl)silyl]oxymethyl]-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-3-yl]-1,3-dithian-2-yl]phenyl]-N'-hydroxyoctanediamide
   Show/Hide
 C34H52N4O7S2Si  1
1
GI50 = 3630.78 nM
   TI
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CP0189379
 Compound Info 
3-benzyl-10-ethyl-8-(trifluoromethyl)-2H-pyrazino[1,2-a]indol-1-one
   Show/Hide
 C21H17F3N2O  1
1
IC50 = 900 nM
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CP0209615
 Compound Info 
5-((1,4-diazepan-1-yl)methyl)-N-(1-(3-fluorobenzyl)-1H-indazol-5-yl)pyrrolo[1,2-f][1,2,4]triazin-4-amine
   Show/Hide
 C26H27FN8  1
1
IC50 = 3600 nM
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CP0219184
 Compound Info 
1-(4-(6,7-dimethoxyquinazolin-4-ylamino)phenyl)-3-phenylurea
   Show/Hide
 C23H21N5O3  1
1
IC50 = 5800 nM
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CP0237627
 Compound Info 
ethyl N-[4-[[6-butoxy-7-[2-(diethylamino)ethoxy]quinazolin-4-yl]amino]-2-chlorophenyl]carbamate
   Show/Hide
 C27H36ClN5O4  1
1
IC50 = 2500 nM
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CP0324893
 Compound Info 
(2E,6E)-4-hydroxy-2,6-bis[(4-nitrophenyl)methylidene]cyclohexan-1-one
   Show/Hide
 C20H16N2O6  1
1
IC50 = 7600 nM
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CP0335787
 Compound Info 
(4-(1-(3-fluorobenzyl)-1H-indazol-5-ylamino)pyrrolo[1,2-f][1,2,4]triazin-5-yl)methanol
   Show/Hide
 C21H17FN6O  1
1
IC50 > 10000 nM
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CP0345034
 Compound Info 
[(2R)-1-(4-tert-butylphenoxy)-3-(2-nitroimidazol-1-yl)propan-2-yl] 4-[(2-hydroxy-5-oxocyclopenta-1,3-dien-1-yl)methylideneamino]benzoate
   Show/Hide
 C29H28N4O7  1
1
GI50 = 13000 nM
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CP0345050
 Compound Info 
4,7,11-trihydroxybenzo[a]pyrrolo[3,4-c]carbazole-1,3(2H,8H)-dione
   Show/Hide
 C18H10N2O5  1
1
IC50 = 26400 nM
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CP0361809
 Compound Info 
(NE)-N-[(3E,5E)-3-[(2-bromo-4,5-dimethoxyphenyl)methylidene]-1-propan-2-yl-5-[(3,5,6-trimethylpyrazin-2-yl)methylidene]piperidin-4-ylidene]hydroxylamine
   Show/Hide
 C25H31BrN4O3  1
1
IC50 = 40 nM
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CP0370065
 Compound Info 
5-(4-chlorophenyl)-2-(4-methoxyphenyl)-[1,3]thiazolo[3,2-b][1,2,4]triazole
   Show/Hide
 C17H12ClN3OS  2
1
GI50 = 2960 nM
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2
LC50 > 50000 nM
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CP0373357
 Compound Info 
2-(3-ethyl-2-(piperidin-1-yl)-3,4-dihydroquinazolin-4-yl)-N-(4-(4-fluorophenylsulfonamido)benzyl)acetamide
   Show/Hide
 C30H34FN5O3S  1
1
GI50 = 13940 nM
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CP0378540
 Compound Info 
7-tert-butylcarbonyloxy-4-hydroxybenzo[a]pyrrolo[3,4-c]carbazole-1,3(2H,8H)-dione
   Show/Hide
 C23H18N2O5  1
1
IC50 = 7280 nM
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CP0378571
 Compound Info 
methyl 2-[2-[5-(dimethylamino)pentyl-methylamino]-3-(4-phenylphenyl)-4H-quinazolin-4-yl]acetate
   Show/Hide
 C31H38N4O2  1
1
GI50 = 520 nM
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CP0378573
 Compound Info 
N-benzyl-2-[2-[5-(dimethylamino)pentyl-methylamino]-3-(4-phenylphenyl)-4H-quinazolin-4-yl]acetamide
   Show/Hide
 C37H43N5O  1
1
GI50 = 40 nM
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CP0390395
 Compound Info 
2-(2-(dimethylamino)-3-phenyl-3,4-dihydroquinazolin-4-yl)-N-(4-nitrobenzyl)acetamide
   Show/Hide
 C25H25N5O3  1
1
GI50 = 22310 nM
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CP0409402
 Compound Info 
5-((4-aminopiperidin-1-yl)methyl)-N-(3-chloro-4-(pyrazin-2-ylmethoxy)phenyl)pyrrolo[1,2-f][1,2,4]triazin-4-amine
   Show/Hide
 C23H25ClN8O  1
1
IC50 = 3500 nM
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CP0409406
 Compound Info 
(S)-N-(1-(3-fluorobenzyl)-1H-indazol-5-yl)-5-((3-aminopyrrolidin-1-yl)methyl)pyrrolo[1,2-f][1,2,4]triazin-4-amine
   Show/Hide
 C25H25FN8  1
1
IC50 = 6500 nM
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CP0412551
 Compound Info 
10-Benzyloxy-1H-pyrido[3'4':4,5]pyrrolo[2,3-a]-pyrrolo[3,4-c]carbazole-5,7-(6H,12H)-dione
   Show/Hide
 C26H16N4O3  1
1
IC50 = 32400 nM
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CP0415101
 Compound Info 
N-dodecyl-2-(5-hydroxy-4-oxo-2-phenylchromen-7-yl)oxyacetamide
   Show/Hide
 C29H37NO5  1
1
IC50 = 16000 nM
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CP0421175
 Compound Info 
methyl 2-[2-[5-[(2-methylpropan-2-yl)oxycarbonylamino]pentylimino]-3-(4-phenylphenyl)-1,4-dihydroquinazolin-4-yl]acetate
   Show/Hide
 C33H40N4O4  1
1
GI50 = 2080 nM
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CP0423570
 Compound Info 
nonyl 2-(5-hydroxy-4-oxo-2-phenylchromen-7-yl)oxyacetate
   Show/Hide
 C26H30O6  1
1
IC50 = 43000 nM
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CP0425261
 Compound Info 
N-(1-benzofuran-5-yl)-N,2,6-trimethylfuro[2,3-d]pyrimidin-4-amine
   Show/Hide
 C17H15N3O2  1
1
GI50 = 51.9 nM
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CP0430674
 Compound Info 
N-[3-[3-[4-[2-(dimethylamino)ethyl]phenyl]pyrazolo[1,5-a]pyrimidin-7-yl]phenyl]-3-(trifluoromethyl)benzamide
   Show/Hide
 C30H26F3N5O  1
1
IC50 = 740 nM
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CP0430758
 Compound Info 
N-(4-bromo-2-fluorophenyl)-7-[2-(diethylamino)ethoxy]-6-methoxyquinazolin-4-amine
   Show/Hide
 C21H24BrFN4O2  1
1
IC50 = 7500 nM
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CP0430799
 Compound Info 
hexadecyl 2-(5-hydroxy-4-oxo-2-phenylchromen-7-yl)oxyacetate
   Show/Hide
 C33H44O6  1
1
IC50 = 8700 nM
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CP0432017
 Compound Info 
N-(6-chloro-1,3-benzothiazol-2-yl)-3-(4-chlorophenyl)-1-phenylpyrazole-4-carboxamide
   Show/Hide
 C23H14Cl2N4OS  1
1
IC50 = 4550 nM
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CP0432230
 Compound Info 
N-(2,3-dihydro-1-benzofuran-5-yl)-N,2,6-trimethylfuro[2,3-d]pyrimidin-4-amine
   Show/Hide
 C17H17N3O2  1
1
GI50 = 32.4 nM
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CP0435748
 Compound Info 
10-Hydroxy-1H-pyrido[3'4':4,5]pyrrolo[2,3-a]pyrrolo[3,4-c]carbazole-5,7-(6H,12H)-dione
   Show/Hide
 C19H10N4O3  1
1
IC50 > 100000 nM
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CP0436503
 Compound Info 
10-Hydroxy-6-methyl-1H-pyrido[3'4':4,5]pyrrolo-[2,3-a]pyrrolo[3,4-c]carbazole-5,7-(6H,12H)-dione
   Show/Hide
 C20H12N4O3  1
1
IC50 = 16200 nM
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CP0437416
 Compound Info 
US9512130, 2
   Show/Hide
 C27H24F5N5O3  1
1
IC50 = 62 nM
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CP0437743
 Compound Info 
N-(4-chlorophenyl)sulfonyl-2-methyl-2-[4-[2-(4-phenyldiazenylphenoxy)ethyl]phenoxy]propanamide
   Show/Hide
 C30H28ClN3O5S  1
1
CC50 > 24000 nM
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CP0438926
 Compound Info 
N-[4-fluoro-3-[3-(1H-pyrazol-4-yl)pyrazolo[1,5-a]pyrimidin-7-yl]phenyl]-3-(trifluoromethyl)benzamide
   Show/Hide
 C23H14F4N6O  1
1
IC50 = 6600 nM
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CP0447763
 Compound Info 
N-[3-[3-[1-(2-pyrrolidin-1-ylethyl)pyrazol-4-yl]pyrazolo[1,5-a]pyrimidin-7-yl]phenyl]-3-(trifluoromethyl)benzamide
   Show/Hide
 C29H26F3N7O  1
1
IC50 = 3300 nM
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CP0451721
 Compound Info 
(1S,7R,10S,16E,21R)-7-benzyl-21-propan-2-yl-2-oxa-12,13-dithia-5,8,20,23-tetrazabicyclo[8.7.6]tricos-16-ene-3,6,9,19,22-pentone
   Show/Hide
 C26H34N4O6S2  1
1
GI50 = 3 nM
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CP0452241
 Compound Info 
N-[3-[3-[2-[2-(dimethylamino)ethyl]phenyl]pyrazolo[1,5-a]pyrimidin-7-yl]phenyl]-3-(trifluoromethyl)benzamide
   Show/Hide
 C30H26F3N5O  1
1
IC50 = 2600 nM
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CP0452778
 Compound Info 
5-((4-aminopiperidin-1-yl)methyl)-N-(3-chloro-4-((5-methylpyridin-3-yl)methoxy)phenyl)pyrrolo[1,2-f][1,2,4]triazin-4-amine
   Show/Hide
 C25H28ClN7O  1
1
IC50 = 3500 nM
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CP0452779
 Compound Info 
5-((4-aminopiperidin-1-yl)methyl)-N-(3-chloro-4-(pyridin-2-ylmethoxy)phenyl)pyrrolo[1,2-f][1,2,4]triazin-4-amine
   Show/Hide
 C24H26ClN7O  1
1
IC50 = 2000 nM
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CP0453059
 Compound Info 
2-(5-hydroxy-4-oxo-2-phenylchromen-7-yl)oxy-N-octadecylacetamide
   Show/Hide
 C35H49NO5  1
1
IC50 = 11000 nM
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CP0453899
 Compound Info 
N-[1-[(3-fluorophenyl)methyl]indazol-5-yl]-5-[[4-(methylamino)piperidin-1-yl]methyl]pyrrolo[2,1-f][1,2,4]triazin-4-amine
   Show/Hide
 C27H29FN8  1
1
IC50 = 7300 nM
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CP0461401
 Compound Info 
2-(2-(dimethylamino)-3-phenyl-3,4-dihydroquinazolin-4-yl)-N-(4-(4-methylphenylsulfonamido)benzyl)acetamide
   Show/Hide
 C32H33N5O3S  1
1
GI50 = 3150 nM
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CP0464497
 Compound Info 
2-[(1E,5E,7E,9R,10R,11E)-10-hydroxy-3,7,9,11-tetramethyltrideca-1,5,7,11-tetraenyl]-6-methoxy-3,5-dimethylpyran-4-one
   Show/Hide
 C25H36O4  2
1
GI50 = 10800 nM
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2
LC50 = 11500 nM
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CP0464652
 Compound Info 
5-[(4-amino-4-methylpiperidin-1-yl)methyl]-N-[1-[(3-fluorophenyl)methyl]indazol-5-yl]pyrrolo[2,1-f][1,2,4]triazin-4-amine
   Show/Hide
 C27H29FN8  1
1
IC50 = 6100 nM
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CP0465282
 Compound Info 
4-N-(4-methoxyphenyl)-4-N-methyl-9H-pyrimido[4,5-b]indole-2,4-diamine
   Show/Hide
 C18H17N5O  1
1
GI50 = 31 nM
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CP0467822
 Compound Info 
2-(1-((4-(1-(3-fluorobenzyl)-1H-indazol-5-ylamino)pyrrolo[1,2-f][1,2,4]triazin-5-yl)methyl)piperidin-4-ylamino)ethanol
   Show/Hide
 C28H31FN8O  1
1
IC50 = 5400 nM
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CP0470150
 Compound Info 
N-[3-[3-[5-[(4-ethylpiperazin-1-yl)methyl]furan-3-yl]pyrazolo[1,5-a]pyrimidin-7-yl]phenyl]-3-(trifluoromethyl)benzamide
   Show/Hide
 C31H29F3N6O2  1
1
IC50 = 2900 nM
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CP0472553
 Compound Info 
2-methoxy-3,5-dimethyl-6-[(1E,5E,7E,11E)-3,7,9,11-tetramethyl-10-[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxytrideca-1,5,7,11-tetraenyl]pyran-4-one
   Show/Hide
 C31H46O9  1
1
GI50 = 690 nM
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CP0480154
 Compound Info 
N-[3-[3-[4-(dimethylamino)phenyl]pyrazolo[1,5-a]pyrimidin-7-yl]phenyl]-3-(trifluoromethyl)benzamide
   Show/Hide
 C28H22F3N5O  1
1
IC50 > 10000 nM
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CP0480155
 Compound Info 
N-[3-[3-[6-(4-methylpiperazin-1-yl)pyridin-3-yl]pyrazolo[1,5-a]pyrimidin-7-yl]phenyl]-3-(trifluoromethyl)benzamide
   Show/Hide
 C30H26F3N7O  1
1
IC50 = 740 nM
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CP0484796
 Compound Info 
6-methoxy-N-[4-[(E)-3-(3-methoxyphenyl)prop-2-enoyl]phenyl]thieno[2,3-b]quinoline-2-carboxamide
   Show/Hide
 C29H22N2O4S  1
1
IC50 = 6700 nM
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CP0487026
 Compound Info 
(1S,5R,6S,9S,15E,20S)-5-hydroxy-20-(2-methylsulfanylethyl)-6-propan-2-yl-2-oxa-11,12-dithia-7,19,22-triazabicyclo[7.7.6]docos-15-ene-3,8,18,21-tetrone
   Show/Hide
 C22H35N3O6S3  1
1
GI50 = 1400 nM
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CP0492010
 Compound Info 
N-(6-chloro-1,3-benzothiazol-2-yl)-3-(4-methoxyphenyl)-1-phenylpyrazole-4-carboxamide
   Show/Hide
 C24H17ClN4O2S  1
1
IC50 = 6570 nM
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CP0492738
 Compound Info 
4-[[(6R)-7-cyano-6-ethyl-5-propan-2-yl-6H-imidazo[1,5-f]pteridin-3-yl]amino]-3-methoxy-N-(1-methylpiperidin-4-yl)benzamide
   Show/Hide
 C28H35N9O2  1
1
EC50 = 6 nM
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CP0493873
 Compound Info 
6-methoxy-N-[4-[(E)-3-(3,4,5-trimethoxyphenyl)prop-2-enoyl]phenyl]thieno[2,3-b]quinoline-2-carboxamide
   Show/Hide
 C31H26N2O6S  1
1
IC50 = 1400 nM
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CP0497053
 Compound Info 
decyl 2-(5-hydroxy-4-oxo-2-phenylchromen-7-yl)oxyacetate
   Show/Hide
 C27H32O6  1
1
IC50 = 31000 nM
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CP0497054
 Compound Info 
dodecyl 2-(5-hydroxy-4-oxo-2-phenylchromen-7-yl)oxyacetate
   Show/Hide
 C29H36O6  1
1
IC50 = 24000 nM
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CP0497857
 Compound Info 
N-[(4-aminophenyl)methyl]-2-[2-(dimethylamino)-3-phenyl-4H-quinazolin-4-yl]acetamide
   Show/Hide
 C25H27N5O  1
1
GI50 = 28280 nM
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CP0499468
 Compound Info 
3-(3-hydroxyphenyl)-2-(pyridin-4-yl)pyrazolo[1,5-a]pyrimidine
   Show/Hide
 C30H28N6O  1
1
IC50 = 270 nM
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CP0500227
 Compound Info 
octyl 2-(5-hydroxy-4-oxo-2-phenylchromen-7-yl)oxyacetate
   Show/Hide
 C25H28O6  1
1
IC50 = 51000 nM
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CP0502039
 Compound Info 
2-(5-hydroxy-4-oxo-2-phenylchromen-7-yl)oxy-N-tetradecylacetamide
   Show/Hide
 C31H41NO5  1
1
IC50 = 8000 nM
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CP0504824
 Compound Info 
2-(5-hydroxy-4-oxo-2-phenylchromen-7-yl)oxy-N-icosylacetamide
   Show/Hide
 C37H53NO5  1
1
IC50 = 19000 nM
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CP0506173
 Compound Info 
N-[3-[3-[4-(pyrrolidin-1-ylmethyl)phenyl]pyrazolo[1,5-a]pyrimidin-7-yl]phenyl]-3-(trifluoromethyl)benzamide
   Show/Hide
 C31H26F3N5O  1
1
IC50 = 2100 nM
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CP0507154
 Compound Info 
3-[7-[3-[[3-(trifluoromethyl)benzoyl]amino]phenyl]pyrazolo[1,5-a]pyrimidin-3-yl]benzamide
   Show/Hide
 C27H18F3N5O2  1
1
IC50 = 3700 nM
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CP0507155
 Compound Info 
N-[3-[3-[4-[[2-(2-methoxyethoxy)acetyl]amino]phenyl]pyrazolo[1,5-a]pyrimidin-7-yl]phenyl]-3-(trifluoromethyl)benzamide
   Show/Hide
 C31H26F3N5O4  1
1
IC50 > 10000 nM
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CP0511625
 Compound Info 
5-[(4-aminopiperidin-1-yl)methyl]-N-[3-chloro-4-[(1-oxidopyridin-1-ium-2-yl)methoxy]phenyl]pyrrolo[2,1-f][1,2,4]triazin-4-amine
   Show/Hide
 C24H26ClN7O2  1
1
IC50 > 5000 nM
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CP0514581
 Compound Info 
N-[3-(3-pyridin-3-ylpyrazolo[1,5-a]pyrimidin-7-yl)phenyl]-3-(trifluoromethyl)benzamide
   Show/Hide
 C25H16F3N5O  1
1
IC50 = 3700 nM
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CP0517556
 Compound Info 
icosyl 2-(5-hydroxy-4-oxo-2-phenylchromen-7-yl)oxyacetate
   Show/Hide
 C37H52O6  1
1
IC50 = 20000 nM
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CP0517983
 Compound Info 
N-[4-[2-[(2S,3S,5S)-2-[[tert-butyl(dimethyl)silyl]oxymethyl]-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-3-yl]-1,3-dithian-2-yl]phenyl]-N'-hydroxyoctanediamide
   Show/Hide
 C34H52N4O7S2Si  1
1
GI50 = 7079.46 nM
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CP0518741
 Compound Info 
hexyl 2-(5-hydroxy-4-oxo-2-phenylchromen-7-yl)oxyacetate
   Show/Hide
 C23H24O6  1
1
IC50 = 77000 nM
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CP0523269
 Compound Info 
2-[4-[[5-fluoro-4-[3-(prop-2-enoylamino)anilino]pyrimidin-2-yl]amino]phenoxy]ethyl N-(pyridin-3-ylmethyl)carbamodithioate
   Show/Hide
 C28H26FN7O2S2  1
1
IC50 = 10200 nM
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CP0525790
 Compound Info 
N-cyclopropyl-4-[5-(2,3-difluoro-4-methoxyphenoxy)-7-(3,3,3-trifluoropropylamino)pyrazolo[1,5-a]pyrimidin-3-yl]-2-methylbenzamide
   Show/Hide
 C27H24F5N5O3  1
1
IC50 = 183 nM
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CP0533498
 Compound Info 
2-chloro-1-[2,4-diamino-6-[2-(4-ethylphenyl)ethyl]-7,8-dihydro-6H-pyrido[3,2-d]pyrimidin-5-yl]ethanone
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 C19H24ClN5O  1
1
IC50 = 3020 nM
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CP0537256
 Compound Info 
(3E,5E)-1-propan-2-yl-3,5-bis[(3,5,6-trimethylpyrazin-2-yl)methylidene]piperidin-4-one
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 C24H31N5O  1
1
IC50 = 900 nM
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CP0537788
 Compound Info 
N-[3-[3-(1H-pyrazol-4-yl)pyrazolo[1,5-a]pyrimidin-7-yl]phenyl]-3-(trifluoromethyl)benzamide
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 C23H15F3N6O  1
1
IC50 = 3700 nM
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CP0538989
 Compound Info 
1-(4-chlorophenyl)-3-[(E)-spiro[3H-chromene-2,1'-cyclopentane]-4-ylideneamino]urea
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 C20H20ClN3O2  1
1
IC50 = 2750 nM
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CP0541956
 Compound Info 
2-(5-hydroxy-4-oxo-2-phenylchromen-7-yl)oxy-N-nonylacetamide
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 C26H31NO5  1
1
IC50 = 39000 nM
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CP0541957
 Compound Info 
N-decyl-2-(5-hydroxy-4-oxo-2-phenylchromen-7-yl)oxyacetamide
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 C27H33NO5  1
1
IC50 = 25000 nM
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CP0542490
 Compound Info 
2-chloro-1-[2,4-diamino-6-[2-(4-propan-2-ylphenyl)ethyl]-7,8-dihydro-6H-pyrido[3,2-d]pyrimidin-5-yl]ethanone
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 C20H26ClN5O  1
1
IC50 = 3430 nM
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CP0543117
 Compound Info 
N-[3-[3-(6-aminopyridin-3-yl)pyrazolo[1,5-a]pyrimidin-7-yl]phenyl]-3-(trifluoromethyl)benzamide
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 C25H17F3N6O  1
1
IC50 = 3400 nM
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CP0543179
 Compound Info 
(3S)-3-(2-benzyl-3-chloro-7-oxo-4,5-dihydropyrazolo[3,4-c]pyridin-6-yl)-5-methyl-4-oxo-2,3-dihydro-1,5-benzoxazepine-8-carbonitrile
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 C24H20ClN5O3  1
1
IC50 = 2 nM
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CP0557086
 Compound Info 
(1S,7S,10S,16E,21R)-7-benzyl-21-propan-2-yl-2-oxa-12,13-dithia-5,8,20,23-tetrazabicyclo[8.7.6]tricos-16-ene-3,6,9,19,22-pentone
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 C26H34N4O6S2  1
1
GI50 = 570 nM
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CP0558747
 Compound Info 
2-(4-methoxyphenyl)-5-phenyl-[1,3]thiazolo[3,2-b][1,2,4]triazole
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 C17H13N3OS  1
1
IC50 = 6600 nM
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CP0569759
 Compound Info 
5-phenyl-2-(3,4,5-trimethoxyphenyl)-[1,3]thiazolo[3,2-b][1,2,4]triazole
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 C19H17N3O3S  1
1
IC50 = 4900 nM
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CP0575901
 Compound Info 
(6R)-5-cyclopentyl-6-ethyl-N-hydroxy-3-[2-methoxy-4-[(1-methylpiperidin-4-yl)carbamoyl]anilino]-N-methyl-6H-imidazo[1,5-f]pteridine-7-carboxamide
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 C31H41N9O4  1
1
EC50 = 60 nM
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CP0578732
 Compound Info 
N-[3-fluoro-4-[6-methoxy-7-[3-(4-methylpiperidin-1-yl)propoxy]quinolin-4-yl]oxyphenyl]-2-[5-(4-fluorophenyl)-1,3,4-oxadiazol-2-yl]propanamide
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 C36H37F2N5O5  1
1
IC50 = 1460 nM
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CP0639539
 Compound Info 
2-[(3R)-3-Methylmorpholin-4-yl]-4-(1-methyl-1H-pyrazol-5-yl)-8-(1H-pyrazol-5-yl)-1,7-naphthyridine
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 C20H21N7O  1
1
IC50 = 160 nM
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CP0669285
 Compound Info 
US8552004, 2.03
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 C21H27N7O2S  1
1
GI50 = 1200 nM
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CP0684598
 Compound Info 
benzo[a]pyrrolo[3,4-c]carbazole-1,3,4,7(2H,8H)-tetraone
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 C18H8N2O4  1
1
IC50 = 17400 nM
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CP0689377
 Compound Info 
SPEBRUTINIB
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 C22H22FN5O3  1
1
IC50 = 18900 nM
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CP0807912
 Compound Info 
((2S,3S)-2-{(R)-4-[4-((R)-2,3-dihydroxy-propoxy)-phenyl]-2,5-dioxo-imidazolidin-1-yl}-N-(2-fluoro-4-iodo-phenyl)-3-phenylbutyramide
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 C28H27FIN3O6  1
1
IC50 = 110 nM
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CP0808811
 Compound Info 
CERALASERTIB
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 C20H24N6O2S  1
1
GI50 = 2600 nM
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CP0863011
 Compound Info 
N,N,N-trimethyl-3-(octadec-1-en-2-ylsulfonyl)propan-1-aminium chloride
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 C24H50ClNO2S  1
1
IC50 = 2110 nM
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CP0885299
 Compound Info 
N-(3-(1H-benzo[d]imidazol-2-yl)-4-chlorophenylcarbamoyl)-4-(2-fluorobenzyloxy)benzamide
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 C28H20ClFN4O3  1
1
IC50 = 590 nM
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CP0895134
 Compound Info 
2-[(3R)-3-Methylmorpholin-4-yl]-8-(1H-pyrazol-5-yl)-4-(pyridin-3-ylethynyl)-1,7-naphthyridine
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 C23H20N6O  1
1
IC50 = 405 nM
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CP0896650
 Compound Info 
9-Chloro-2-(3,4-dimethoxyphenylamino)-5H-benzo[b]-pyrimido[4,5-d]azepin-6(7H)-one
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 C20H17ClN4O3  1
1
LD50 = 3300 nM
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CP0901624
 Compound Info 
4-(6,7-Dihydro-5H-pyrrolo[1,2-a]imidazol-3-yl)-2-[(3R)-3-methylmorpholin-4-yl]-8-(1H-pyrazol-5-yl)-1,7-naphthyridine
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 C22H23N7O  1
1
IC50 = 125 nM
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CP0906523
 Compound Info 
7-Benzyl-N-(4-methoxyphenyl)-N,2,5-trimethyl-5H-pyrrolo[3,2-d]pyrimidin-4-amine hydrochloride
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 C23H25ClN4O  1
1
GI50 = 35.1 nM
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CP0911977
 Compound Info 
N-(4-Methoxyphenyl)-N,2-dimethyl-6,7-dihydro-5H-cyclopenta-[d]pyrimidin-4-aminium Chloride
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 C16H20ClN3O  1
1
GI50 < 10 nM
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CP0917967
 Compound Info 
2,2'-[{8-[(2-{4-[(2,4-dDioxo-1,3-thiazolidin-5-yl)methyl]phenoxy}-ethyl)(methyl)amino]-8-oxooctane-1,3-diyl}bis(thio)]bis(2-oxoethanaminium) dichloride
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 C25H38Cl2N4O6S3  1
1
IC50 = 8000 nM
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CP0958488
 Compound Info 
4-Isopropoxy-2-[(3R)-3-methylmorpholin-4-yl]-8-(1H-pyrazol-5-yl)-1,7-naphthyridine
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 C19H23N5O2  1
1
IC50 = 929 nM
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Protein family and CMB statistics Related to the Cell Line
Cell Lines Derived from the same Tissue Source (Colon)
Cell Line Name Organism Disease
SW480
 Cell Line Info 
Homo sapiens (Human) Colon adenocarcinoma
Caco-2
 Cell Line Info 
Homo sapiens (Human) Colon adenocarcinoma
HCA7
 Cell Line Info 
Homo sapiens (Human) Colon adenocarcinoma
LS174T
 Cell Line Info 
Homo sapiens (Human) Colon adenocarcinoma
LS180
 Cell Line Info 
Homo sapiens (Human) Colon adenocarcinoma
SW1116
 Cell Line Info 
Homo sapiens (Human) Colon adenocarcinoma
WiDr
 Cell Line Info 
Homo sapiens (Human) Colon adenocarcinoma
S1-M1-80
 Cell Line Info 
Homo sapiens (Human) Colon adenocarcinoma
SW48
 Cell Line Info 
Homo sapiens (Human) Colon adenocarcinoma
S1
 Cell Line Info 
Homo sapiens (Human) Colon adenocarcinoma
Caco-2/TC-7
 Cell Line Info 
Homo sapiens (Human) Colon adenocarcinoma
COLO 320DM
 Cell Line Info 
Homo sapiens (Human) Colon adenocarcinoma
COLO 320
 Cell Line Info 
Homo sapiens (Human) Colon adenocarcinoma
HCT 116
 Cell Line Info 
Homo sapiens (Human) Colon carcinoma
RKO
 Cell Line Info 
Homo sapiens (Human) Colon carcinoma
KM12-Luc
 Cell Line Info 
Homo sapiens (Human) Colon carcinoma
TC71
 Cell Line Info 
Homo sapiens (Human) Colon carcinoma
KM12
 Cell Line Info 
Homo sapiens (Human) Colon carcinoma
KM12-L4A
 Cell Line Info 
Homo sapiens (Human) Colon carcinoma
HCA2
 Cell Line Info 
Homo sapiens (Human) Rectosigmoid adenocarcinoma
CT26
 Cell Line Info 
Mus musculus (Mouse) Mouse colon adenocarcinoma
51B LiM-1
 Cell Line Info 
Mus musculus (Mouse) Mouse colon adenocarcinoma
GLUTag
 Cell Line Info 
Mus musculus (Mouse) Neuroendocrine cell carcinoma of the mouse intestinal tract
CC531
 Cell Line Info 
Rattus norvegicus (Rat) Adenocarcinoma of the rat colon