| Compound ID |
Compound Name |
Compound Formula |
|
CP0528901
|
4-(1-acetylpiperidin-4-yl)-N-(diaminomethylidene)-2-methyl-5-(trifluoromethyl)benzamide
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|
C17H21F3N4O2
|
1
|
| 1 |
IC50 = 5 nM
|
|
|
|
CP0024264
|
4-(1-acetylpiperidin-4-yl)-N-(diaminomethylidene)-3-(trifluoromethyl)benzamide
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|
C16H19F3N4O2
|
1
|
| 1 |
IC50 = 6 nM
|
|
|
|
CP0412885
|
N-(diaminomethylidene)-4-[1-(2-methoxyacetyl)piperidin-4-yl]-3-(trifluoromethyl)benzamide
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|
C17H21F3N4O3
|
1
|
| 1 |
IC50 = 10 nM
|
|
|
|
CP0412886
|
N-(diaminomethylidene)-4-(1-propanoylpiperidin-4-yl)-3-(trifluoromethyl)benzamide
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|
C17H21F3N4O2
|
1
|
| 1 |
IC50 = 11 nM
|
|
|
|
CP0410381
|
N-(diaminomethylidene)-4-[1-(1-methylimidazole-2-carbonyl)piperidin-4-yl]-3-(trifluoromethyl)benzamide
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|
C19H21F3N6O2
|
1
|
| 1 |
IC50 = 14 nM
|
|
|
|
CP0426695
|
N-(diaminomethylidene)-4-[1-(4-sulfamoylbenzoyl)piperidin-4-yl]-3-(trifluoromethyl)benzamide
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|
C21H22F3N5O4S
|
1
|
| 1 |
IC50 = 14 nM
|
|
|
|
CP0385540
|
N-(diaminomethylidene)-4-[1-(4-methylsulfonylbenzoyl)piperidin-4-yl]-3-(trifluoromethyl)benzamide
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|
C22H23F3N4O4S
|
1
|
| 1 |
IC50 = 15 nM
|
|
|
|
CP0487978
|
4-(1-acetylpiperidin-4-yl)-N-(diaminomethylidene)-2-methyl-5-methylsulfonylbenzamide
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|
C17H24N4O4S
|
1
|
| 1 |
IC50 = 15 nM
|
|
|
|
CP0542310
|
N-(diaminomethylidene)-2-methyl-5-methylsulfonyl-4-(1-propanoylpiperidin-4-yl)benzamide
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|
C18H26N4O4S
|
1
|
| 1 |
IC50 = 15 nM
|
|
|
|
CP0528902
|
4-[1-(cyclopropanecarbonyl)piperidin-4-yl]-N-(diaminomethylidene)-3-(trifluoromethyl)benzamide
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|
C18H21F3N4O2
|
1
|
| 1 |
IC50 = 16 nM
|
|
|
|
CP0385539
|
N-(diaminomethylidene)-4-[1-(pyridine-2-carbonyl)piperidin-4-yl]-3-(trifluoromethyl)benzamide
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|
C20H20F3N5O2
|
1
|
| 1 |
IC50 = 18 nM
|
|
|
|
CP0443902
|
N-(diaminomethylidene)-4-[1-(pyridine-3-carbonyl)piperidin-4-yl]-3-(trifluoromethyl)benzamide
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|
C20H20F3N5O2
|
1
|
| 1 |
IC50 = 18 nM
|
|
|
|
CP0488523
|
N-(diaminomethylidene)-4-[1-(pyridine-4-carbonyl)piperidin-4-yl]-3-(trifluoromethyl)benzamide
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|
C20H20F3N5O2
|
1
|
| 1 |
IC50 = 18 nM
|
|
|
|
CP0493521
|
N-(diaminomethylidene)-4-[1-(3-methylimidazole-4-carbonyl)piperidin-4-yl]-3-(trifluoromethyl)benzamide
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|
C19H21F3N6O2
|
1
|
| 1 |
IC50 = 18 nM
|
|
|
|
CP0522526
|
N-(diaminomethylidene)-4-[1-(6-oxo-1H-pyridine-3-carbonyl)piperidin-4-yl]-3-(trifluoromethyl)benzamide
Show/Hide
|
C20H20F3N5O3
|
1
|
| 1 |
IC50 = 19 nM
|
|
|
|
CP0544261
|
4-(1-acetylpiperidin-4-yl)-N-(diaminomethylidene)-2-methoxy-5-(trifluoromethyl)benzamide
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|
C17H21F3N4O3
|
1
|
| 1 |
IC50 = 19 nM
|
|
|
|
CP0508500
|
N-(diaminomethylidene)-4-[1-(4-hydroxybenzoyl)piperidin-4-yl]-3-(trifluoromethyl)benzamide
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|
C21H21F3N4O3
|
1
|
| 1 |
IC50 = 21 nM
|
|
|
|
CP0547751
|
4-(1-acetylpiperidin-4-yl)-N-(diaminomethylidene)-3-methylsulfonylbenzamide
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|
C16H22N4O4S
|
1
|
| 1 |
IC50 = 22 nM
|
|
|
|
CP0453555
|
4-[1-(4-cyanobenzoyl)piperidin-4-yl]-N-(diaminomethylidene)-3-(trifluoromethyl)benzamide
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|
C22H20F3N5O2
|
1
|
| 1 |
IC50 = 24 nM
|
|
|
|
CP0540923
|
4-[1-(4-carbamoylbenzoyl)piperidin-4-yl]-N-(diaminomethylidene)-3-(trifluoromethyl)benzamide
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|
C22H22F3N5O3
|
1
|
| 1 |
IC50 = 26 nM
|
|
|
|
CP0470441
|
N-(diaminomethylidene)-4-[1-(1,5-dimethylpyrazole-3-carbonyl)piperidin-4-yl]-3-(trifluoromethyl)benzamide
Show/Hide
|
C20H23F3N6O2
|
1
|
| 1 |
IC50 = 27 nM
|
|
|
|
CP0381155
|
N-(diaminomethylidene)-4-[1-(2-methylpropanoyl)piperidin-4-yl]-3-(trifluoromethyl)benzamide
Show/Hide
|
C18H23F3N4O2
|
1
|
| 1 |
IC50 = 28 nM
|
|
|
|
CP0540926
|
SABIPORIDE
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|
C18H19F3N6O2
|
1
|
| 1 |
IC50 = 28 nM
|
|
|
|
CP0453556
|
N-(diaminomethylidene)-3-methylsulfonyl-4-(1-propanoylpiperidin-4-yl)benzamide
Show/Hide
|
C17H24N4O4S
|
1
|
| 1 |
IC50 = 29 nM
|
|
|
|
CP0534112
|
4-(1-butanoylpiperidin-4-yl)-N-(diaminomethylidene)-3-(trifluoromethyl)benzamide
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|
C18H23F3N4O2
|
1
|
| 1 |
IC50 = 29 nM
|
|
|
|
CP0397552
|
N-(diaminomethylidene)-4-[1-[4-(methylsulfamoyl)benzoyl]piperidin-4-yl]-3-(trifluoromethyl)benzamide
Show/Hide
|
C22H24F3N5O4S
|
1
|
| 1 |
IC50 = 30 nM
|
|
|
|
CP0540924
|
N-(diaminomethylidene)-4-[1-[3-(1,3-oxazol-5-yl)benzoyl]piperidin-4-yl]-3-(trifluoromethyl)benzamide
Show/Hide
|
C24H22F3N5O3
|
1
|
| 1 |
IC50 = 33 nM
|
|
|
|
CP0381144
|
4-[1-(3-cyanobenzoyl)piperidin-4-yl]-N-(diaminomethylidene)-3-(trifluoromethyl)benzamide
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|
C22H20F3N5O2
|
1
|
| 1 |
IC50 = 35 nM
|
|
|
|
CP0488169
|
N-[1-[4-(diaminomethylidenecarbamoyl)-2-(trifluoromethyl)phenyl]pyrrolidin-3-yl]-1H-pyrrole-2-carboxamide
Show/Hide
|
C18H19F3N6O2
|
1
|
| 1 |
IC50 = 36 nM
|
|
|
|
CP0547753
|
N-(diaminomethylidene)-4-[1-[4-(dimethylsulfamoyl)benzoyl]piperidin-4-yl]-3-(trifluoromethyl)benzamide
Show/Hide
|
C23H26F3N5O4S
|
1
|
| 1 |
IC50 = 36 nM
|
|
|
|
CP0443905
|
N-[1-[4-(diaminomethylidenecarbamoyl)-2-(trifluoromethyl)phenyl]piperidin-4-yl]-1H-pyrrole-2-carboxamide
Show/Hide
|
C19H21F3N6O2
|
1
|
| 1 |
IC50 = 41 nM
|
|
|
|
CP0540925
|
N-(diaminomethylidene)-4-[1-(1H-pyrrole-2-carbonyl)piperidin-4-yl]-3-(trifluoromethyl)benzamide
Show/Hide
|
C19H20F3N5O2
|
1
|
| 1 |
IC50 = 45 nM
|
|
|
|
CP0507316
|
N-(diaminomethylidene)-4-[1-(3-methylbutanoyl)piperidin-4-yl]-3-(trifluoromethyl)benzamide
Show/Hide
|
C19H25F3N4O2
|
1
|
| 1 |
IC50 = 47 nM
|
|
|
|
CP0446233
|
N-(diaminomethylidene)-4-[1-[4-(dimethylcarbamoyl)benzoyl]piperidin-4-yl]-3-(trifluoromethyl)benzamide
Show/Hide
|
C24H26F3N5O3
|
1
|
| 1 |
IC50 = 50 nM
|
|
|
|
CP0544263
|
N-(diaminomethylidene)-4-[1-[4-(methylcarbamoyl)benzoyl]piperidin-4-yl]-3-(trifluoromethyl)benzamide
Show/Hide
|
C23H24F3N5O3
|
1
|
| 1 |
IC50 = 52 nM
|
|
|
|
CP0500296
|
N-(diaminomethylidene)-4-[1-(2-methylsulfonylbenzoyl)piperidin-4-yl]-3-(trifluoromethyl)benzamide
Show/Hide
|
C22H23F3N4O4S
|
1
|
| 1 |
IC50 = 58 nM
|
|
|
|
CP0381143
|
N-(diaminomethylidene)-4-[1-(3-methylsulfonylbenzoyl)piperidin-4-yl]-3-(trifluoromethyl)benzamide
Show/Hide
|
C22H23F3N4O4S
|
1
|
| 1 |
IC50 = 60 nM
|
|
|
|
CP0413694
|
4-[1-(2-cyanobenzoyl)piperidin-4-yl]-N-(diaminomethylidene)-3-(trifluoromethyl)benzamide
Show/Hide
|
C22H20F3N5O2
|
1
|
| 1 |
IC50 = 61 nM
|
|
|
|
CP0547752
|
4-[1-(cyclopentanecarbonyl)piperidin-4-yl]-N-(diaminomethylidene)-3-(trifluoromethyl)benzamide
Show/Hide
|
C20H25F3N4O2
|
1
|
| 1 |
IC50 = 64 nM
|
|
|
|
CP0426696
|
N-(diaminomethylidene)-4-[1-(4-imidazol-1-ylbenzoyl)piperidin-4-yl]-3-(trifluoromethyl)benzamide
Show/Hide
|
C24H23F3N6O2
|
1
|
| 1 |
IC50 = 65 nM
|
|
|
|
CP0470438
|
4-(1-benzoylpiperidin-4-yl)-N-(diaminomethylidene)-3-(trifluoromethyl)benzamide
Show/Hide
|
C21H21F3N4O2
|
1
|
| 1 |
IC50 = 68 nM
|
|
|
|
CP0479543
|
N-(diaminomethylidene)-4-[1-(2,2-dimethylpropanoyl)piperidin-4-yl]-3-(trifluoromethyl)benzamide
Show/Hide
|
C19H25F3N4O2
|
1
|
| 1 |
IC50 = 72 nM
|
|
|
|
CP0381145
|
N-(diaminomethylidene)-4-[1-[4-(1,3-oxazol-5-yl)benzoyl]piperidin-4-yl]-3-(trifluoromethyl)benzamide
Show/Hide
|
C24H22F3N5O3
|
1
|
| 1 |
IC50 = 102 nM
|
|
|
|
CP0443903
|
4-[1-(2-chlorobenzoyl)piperidin-4-yl]-N-(diaminomethylidene)-3-(trifluoromethyl)benzamide
Show/Hide
|
C21H20ClF3N4O2
|
1
|
| 1 |
IC50 = 108 nM
|
|
|
|
CP0453794
|
N-(diaminomethylidene)-4-[1-(4-fluorobenzoyl)piperidin-4-yl]-3-(trifluoromethyl)benzamide
Show/Hide
|
C21H20F4N4O2
|
1
|
| 1 |
IC50 = 109 nM
|
|
|
|
CP0542311
|
N-(diaminomethylidene)-4-[1-(4-methoxybenzoyl)piperidin-4-yl]-3-(trifluoromethyl)benzamide
Show/Hide
|
C22H23F3N4O3
|
1
|
| 1 |
IC50 = 132 nM
|
|
|
|
CP0488524
|
N-[1-[4-(diaminomethylidenecarbamoyl)-2-(trifluoromethyl)phenyl]piperidin-3-yl]-1H-pyrrole-2-carboxamide
Show/Hide
|
C19H21F3N6O2
|
1
|
| 1 |
IC50 = 172 nM
|
|
|
|
CP0381146
|
4-[1-(4-chlorobenzoyl)piperidin-4-yl]-N-(diaminomethylidene)-3-(trifluoromethyl)benzamide
Show/Hide
|
C21H20ClF3N4O2
|
1
|
| 1 |
IC50 = 306 nM
|
|
|
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CP0453793
|
N-(diaminomethylidene)-3-(trifluoromethyl)-4-[1-[4-(trifluoromethyl)benzoyl]piperidin-4-yl]benzamide
Show/Hide
|
C22H20F6N4O2
|
1
|
| 1 |
IC50 = 320 nM
|
|
|
|
CP0443904
|
4-[1-(3-chlorobenzoyl)piperidin-4-yl]-N-(diaminomethylidene)-3-(trifluoromethyl)benzamide
Show/Hide
|
C21H20ClF3N4O2
|
1
|
| 1 |
IC50 = 385 nM
|
|
|
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CP0470442
|
N-(diaminomethylidene)-4-[1-(4-phenylbenzoyl)piperidin-4-yl]-3-(trifluoromethyl)benzamide
Show/Hide
|
C27H25F3N4O2
|
1
|
| 1 |
IC50 = 4705 nM
|
|
|
