General Information of the Cell Line
Cell Line ID
CL000189
Cell Line Name
RKO
Category
Cancer cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_0504
Tissue Information
Colon
Disease
Colon carcinoma (NCIt: C4910)
Map of Molecular Bioactivity Related to the Cell Line
Map of Molecular Bioactivity Related to the Cell Line

Cell Line
Protein
Compound

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Cell Line
Protein ID: PT00962, Glycogen synthase kinase-3 beta
 Protein Info 
Compound ID Compound Name Compound Formula
CP0203751
 Compound Info 
N-[3-[4-(3,4-dimethylphenyl)piperazin-1-yl]propyl]-3-pyridin-3-yl-1,2,4-oxadiazole-5-carboxamide
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C23H28N6O2
  1
1
IC50 = 16000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0156497
 Compound Info 
N-[3-[2-methyl-4-(3-methylphenyl)piperazin-1-yl]propyl]-3-pyridin-3-yl-1,2,4-oxadiazole-5-carboxamide
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C23H28N6O2
  1
1
IC50 = 17000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0185912
 Compound Info 
N-[3-[3-methyl-4-(3-methylphenyl)piperazin-1-yl]propyl]-3-pyridin-3-yl-1,2,4-oxadiazole-5-carboxamide
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C23H28N6O2
  1
1
IC50 = 19150 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0156498
 Compound Info 
N-[3-[4-(2-methoxyphenyl)piperazin-1-yl]propyl]-3-pyridin-3-yl-1,2,4-oxadiazole-5-carboxamide
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C22H26N6O3
  1
1
IC50 = 23000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0205656
 Compound Info 
N-[3-[3-methyl-4-(3-methylphenyl)piperazin-1-yl]propyl]-3-pyridin-4-yl-1,2,4-oxadiazole-5-carboxamide
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C23H28N6O2
  1
1
IC50 > 50000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
Protein ID: PT03462, GTPase KRas
 Protein Info 
Protein ID: PT02499, Ubiquitin carboxyl-terminal hydrolase 7
 Protein Info 
Cell Viability or Cytotoxicity Assay
Compound ID Compound Name Compound Formula
CP0095287
 Compound Info 
[4-(3-chloroanilino)thieno[2,3-d]pyrimidin-6-yl]-(1H-indol-2-yl)methanone
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 C21H13ClN4OS  1
1
IC50 = 18100 nM
   TI
   LI
   LO
   TS
CP0145985
 Compound Info 
4-[5-[(E)-2-[4-(2-chlorophenyl)-5-(5-methylsulfonylpyridin-2-yl)-1,2,4-triazol-3-yl]ethenyl]-1,3,4-oxadiazol-2-yl]benzonitrile
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 C25H16ClN7O3S  1
1
GI50 = 8900 nM
   TI
   LI
   LO
   TS
CP0384974
 Compound Info 
2-ethylsulfanylcarbothioylsulfanyl-1-(4-methoxyphenyl)ethanone
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 C12H14O2S3  1
1
IC50 = 1995.26 nM
   TI
   LI
   LO
   TS
CP0961810
 Compound Info 
(E)-3-(3-chlorophenyl)-N-(2-((1,1-dioxidotetrahydro-2H-thiopyran-4-yl)(methyl)amino)-2-oxoethyl)acrylamide
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 C17H21ClN2O4S  1
1
IC50 = 11720 nM
   TI
   LI
   LO
   TS
Protein family and CMB statistics Related to the Cell Line
Cell Lines Derived from the same Tissue Source (Colon)
Cell Line Name Organism Disease
HT-29
 Cell Line Info 
Homo sapiens (Human) Colon adenocarcinoma
SW480
 Cell Line Info 
Homo sapiens (Human) Colon adenocarcinoma
Caco-2
 Cell Line Info 
Homo sapiens (Human) Colon adenocarcinoma
HCA7
 Cell Line Info 
Homo sapiens (Human) Colon adenocarcinoma
LS174T
 Cell Line Info 
Homo sapiens (Human) Colon adenocarcinoma
LS180
 Cell Line Info 
Homo sapiens (Human) Colon adenocarcinoma
SW1116
 Cell Line Info 
Homo sapiens (Human) Colon adenocarcinoma
WiDr
 Cell Line Info 
Homo sapiens (Human) Colon adenocarcinoma
S1-M1-80
 Cell Line Info 
Homo sapiens (Human) Colon adenocarcinoma
SW48
 Cell Line Info 
Homo sapiens (Human) Colon adenocarcinoma
S1
 Cell Line Info 
Homo sapiens (Human) Colon adenocarcinoma
Caco-2/TC-7
 Cell Line Info 
Homo sapiens (Human) Colon adenocarcinoma
COLO 320DM
 Cell Line Info 
Homo sapiens (Human) Colon adenocarcinoma
COLO 320
 Cell Line Info 
Homo sapiens (Human) Colon adenocarcinoma
HCT 116
 Cell Line Info 
Homo sapiens (Human) Colon carcinoma
KM12-Luc
 Cell Line Info 
Homo sapiens (Human) Colon carcinoma
TC71
 Cell Line Info 
Homo sapiens (Human) Colon carcinoma
KM12
 Cell Line Info 
Homo sapiens (Human) Colon carcinoma
KM12-L4A
 Cell Line Info 
Homo sapiens (Human) Colon carcinoma
HCA2
 Cell Line Info 
Homo sapiens (Human) Rectosigmoid adenocarcinoma
CT26
 Cell Line Info 
Mus musculus (Mouse) Mouse colon adenocarcinoma
51B LiM-1
 Cell Line Info 
Mus musculus (Mouse) Mouse colon adenocarcinoma
GLUTag
 Cell Line Info 
Mus musculus (Mouse) Neuroendocrine cell carcinoma of the mouse intestinal tract
CC531
 Cell Line Info 
Rattus norvegicus (Rat) Adenocarcinoma of the rat colon