| Compound ID |
Compound Name |
Compound Formula |
|
CP0100081
|
3-[[7-[5-chloro-3-methyl-2-[[(2R)-morpholin-2-yl]methyl]phenyl]thieno[3,2-b]pyridin-2-yl]methyl]-6,6-dimethyl-3-azabicyclo[3.1.0]hexane-2,4-dione
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|
C27H28ClN3O3S
|
1
|
| 1 |
EC50 = 25 nM
|
|
|
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CP0367316
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3-[[7-[5-chloro-3-methyl-2-(piperidin-3-ylamino)phenyl]thieno[3,2-b]pyridin-2-yl]methyl]-6,6-dimethyl-3-azabicyclo[3.1.0]hexane-2,4-dione
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|
C27H29ClN4O2S
|
1
|
| 1 |
EC50 = 33 nM
|
|
|
|
CP0368600
|
3-[[7-[5-chloro-3-methyl-2-[[(2R)-morpholin-2-yl]methyl]phenyl]thieno[3,2-b]pyridin-2-yl]methyl]-3-azabicyclo[3.1.0]hexane-2,4-dione
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|
C25H24ClN3O3S
|
1
|
| 1 |
EC50 = 35 nM
|
|
|
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CP0125761
|
3-[[7-[5-chloro-3-methyl-2-[(3S,4R)-3-methylpiperidin-4-yl]oxyphenyl]thieno[3,2-b]pyridin-2-yl]methyl]-1-(2,2,2-trifluoroethyl)pyrimidine-2,4-dione
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|
C27H26ClF3N4O3S
|
1
|
| 1 |
EC50 = 42 nM
|
|
|
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CP0330144
|
3-[[7-[5-chloro-3-methyl-2-[[(2R,6R)-6-methylmorpholin-2-yl]methyl]phenyl]thieno[3,2-b]pyridin-2-yl]methyl]-3-azabicyclo[3.1.0]hexane-2,4-dione
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|
C26H26ClN3O3S
|
1
|
| 1 |
EC50 = 60 nM
|
|
|
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CP0368599
|
1-[[7-[5-chloro-2-[[(2S,6S)-2,6-dimethylpiperazin-1-yl]methyl]-3-methylphenyl]thieno[3,2-b]pyridin-2-yl]methyl]pyrrolidine-2,5-dione
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|
C26H29ClN4O2S
|
1
|
| 1 |
EC50 = 60 nM
|
|
|
|
CP0127566
|
3-[[7-[5-chloro-3-methyl-2-[(3S,4R)-3-methylpiperidin-4-yl]oxyphenyl]thieno[3,2-b]pyridin-2-yl]methyl]-6,6-dimethyl-3-azabicyclo[3.1.0]hexane-2,4-dione
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|
C28H30ClN3O3S
|
1
|
| 1 |
EC50 = 65 nM
|
|
|
|
CP0533397
|
3-[[7-[5-chloro-3-methyl-2-(piperidin-3-ylmethyl)phenyl]thieno[3,2-b]pyridin-2-yl]methyl]-6,6-dimethyl-3-azabicyclo[3.1.0]hexane-2,4-dione
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|
C28H30ClN3O2S
|
1
|
| 1 |
EC50 = 130 nM
|
|
|
|
CP0100079
|
1-[[7-[2-(3-aminocyclobutyl)oxy-5-chloro-3-methylphenyl]thieno[3,2-b]pyridin-2-yl]methyl]pyrrolidine-2,5-dione
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|
C23H22ClN3O3S
|
1
|
| 1 |
EC50 = 150 nM
|
|
|
|
CP0357846
|
1-[[7-[5-chloro-3-methyl-2-[(3S,4R)-3-methylpiperidin-4-yl]oxyphenyl]thieno[3,2-b]pyridin-2-yl]methyl]pyrrolidine-2,5-dione
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|
C25H26ClN3O3S
|
1
|
| 1 |
EC50 = 150 nM
|
|
|
|
CP0339426
|
3-[[7-[5-chloro-3-methyl-2-[(3S,4R)-3-methylpiperidin-4-yl]oxyphenyl]thieno[3,2-b]pyridin-2-yl]methyl]-3-azabicyclo[3.1.0]hexane-2,4-dione
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|
C26H26ClN3O3S
|
1
|
| 1 |
EC50 = 170 nM
|
|
|
|
CP0207780
|
1-[[7-[5-chloro-3-methyl-2-[(3S)-piperidin-3-yl]oxyphenyl]thieno[3,2-b]pyridin-2-yl]methyl]pyrrolidine-2,5-dione
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|
C24H24ClN3O3S
|
1
|
| 1 |
EC50 = 180 nM
|
|
|
|
CP0517573
|
3-[[7-[5-chloro-3-methyl-2-[[(2R,3R)-3-methylmorpholin-2-yl]methyl]phenyl]thieno[3,2-b]pyridin-2-yl]methyl]-3-azabicyclo[3.1.0]hexane-2,4-dione
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|
C26H26ClN3O3S
|
1
|
| 1 |
EC50 = 210 nM
|
|
|
|
CP0207782
|
3-[[7-(5-chloro-3-methyl-2-piperidin-3-yloxyphenyl)thieno[3,2-b]pyridin-2-yl]methyl]-6,6-dimethyl-3-azabicyclo[3.1.0]hexane-2,4-dione
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|
C27H28ClN3O3S
|
1
|
| 1 |
EC50 = 250 nM
|
|
|
|
CP0207781
|
1-[[7-[5-chloro-3-methyl-2-[[(2S)-2-methylpiperazin-1-yl]methyl]phenyl]thieno[3,2-b]pyridin-2-yl]methyl]pyrrolidine-2,5-dione
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|
C25H27ClN4O2S
|
1
|
| 1 |
EC50 = 280 nM
|
|
|
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CP0354704
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1-[[7-[5-chloro-2-[(3-fluoroazetidin-3-yl)methoxy]-3-methylphenyl]thieno[3,2-b]pyridin-2-yl]methyl]pyrrolidine-2,5-dione
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|
C23H21ClFN3O3S
|
1
|
| 1 |
EC50 = 320 nM
|
|
|
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CP0367315
|
1-[[7-(5-chloro-3-methyl-2-piperidin-4-yloxyphenyl)thieno[3,2-b]pyridin-2-yl]methyl]pyrrolidine-2,5-dione
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|
C24H24ClN3O3S
|
1
|
| 1 |
EC50 = 400 nM
|
|
|
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CP0340635
|
1-[[7-[5-chloro-2-[(3R,4S)-4-fluoropyrrolidin-3-yl]oxy-3-methylphenyl]thieno[3,2-b]pyridin-2-yl]methyl]pyrrolidine-2,5-dione
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|
C23H21ClFN3O3S
|
1
|
| 1 |
EC50 = 560 nM
|
|
|
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CP0339427
|
1-[[7-[5-chloro-3-methyl-2-(piperazin-1-ylmethyl)phenyl]thieno[3,2-b]pyridin-2-yl]methyl]pyrrolidine-2,5-dione
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|
C24H25ClN4O2S
|
1
|
| 1 |
EC50 = 1200 nM
|
|
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